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Journal Article
MOLECULAR PHARMACOLOGY, ISSN 0026-895X, 08/2019, Volume 96, Issue 2, pp. 128 - 137
Drug transporters play a crucial role in pharmacokinetics. One subfamily of transporters with proven clinical relevance are the OATP1 B transporters. Recently... 
ORGANIC ANION TRANSPORTER | BIOTRANSFORMATION | POLYMORPHISMS | ACID | GLUCURONIDE METABOLITE | TROGLITAZONE | PHARMACOLOGY & PHARMACY | HEPATIC-UPTAKE | CLINICAL PHARMACOKINETICS | IDENTIFICATION | STATINS
Journal Article
BBA - Gene Regulatory Mechanisms, ISSN 1874-9399, 04/2019, Volume 1862, Issue 4, pp. 447 - 456
PDZK1 (NHERF3) interacts with membrane proteins whereby modulating their spatial arrangement, membrane stability, and function. One of the membrane proteins... 
HDL | PDZ domain | PDZK1 | PXR | Scaffold protein | LXR | SR-BI | DOMAIN | B TYPE-I | SURFACE LOCALIZATION | LIPID-METABOLISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | PREGNANE-X-RECEPTOR | HEPATIC SCAVENGER RECEPTOR | BIOPHYSICS | CHOLESTEROL TRANSPORT | LIVER | DENSITY-LIPOPROTEIN RECEPTOR
Journal Article
Molecular Pharmaceutics, ISSN 1543-8384, 12/2018, Volume 15, Issue 12, pp. 5501 - 5513
The organic anion transporting polypeptide (OATP) 2B1 is ubiquitously expressed and known to facilitate cellular entry. It is widely accepted that transport... 
organic anion transport | competitive counterflow | drug transporter | substrate identification | OATP2B1 | MEDICINE, RESEARCH & EXPERIMENTAL | PEPTIDE 2B1 | OATP-B | ATORVASTATIN | IN-VITRO | DRUG TRANSPORTERS | EFFLUX | GRAPEFRUIT JUICE | PHARMACOLOGY & PHARMACY | INHIBITORS | VECTORIAL TRANSPORT | EXPRESSION
Journal Article
European Journal of Clinical Pharmacology, ISSN 0031-6970, 3/2018, Volume 74, Issue 3, pp. 275 - 283
Methylenedioxymethamphetamine (MDMA, ecstasy) is used recreationally and frequently leads to sympathomimetic toxicity. MDMA produces cardiovascular and... 
Pharmacogenetics | Biomedicine | Norepinephrine transporter | Pharmacology/Toxicology | SLC6A2 | Cardiostimulation | MDMA | POSTTRAUMATIC-STRESS-DISORDER | HEALTHY-SUBJECTS | HUMANS | SEROTONIN TRANSPORTERS | BLOOD-PRESSURE | RESPONSES | ECSTASY | POLYMORPHISMS | PHARMACOKINETICS | 3,4-METHYLENEDIOXYMETHAMPHETAMINE | PHARMACOLOGY & PHARMACY | Cardiotoxins - toxicity | Humans | Male | Young Adult | Heart Rate - drug effects | Norepinephrine Plasma Membrane Transport Proteins - genetics | Adult | Cardiovascular Physiological Phenomena - drug effects | Female | Blood Pressure - drug effects | Pharmacogenetics - methods | Double-Blind Method | Genetic Association Studies | Gene Frequency | Switzerland | Cross-Over Studies | Adolescent | Alleles | Heterozygote | N-Methyl-3,4-methylenedioxyamphetamine - toxicity | Polymorphism, Single Nucleotide | Psychotropic Drugs - toxicity | Street Drugs - toxicity | Norepinephrine Plasma Membrane Transport Proteins - metabolism | Adrenergic Uptake Inhibitors - toxicity | Genetic research | Heart beat | Single nucleotide polymorphisms | Analysis | Genes | Toxicity | Stimulation | Single-nucleotide polymorphism | Carriers | Heart rate | Genetic variance | Genotype & phenotype | Receptors | Adrenergic receptors | Blood pressure | Norepinephrine | Transporter | Receptors (physiology) | Polymorphism | Index Medicus
Journal Article
Molecular Pharmaceutics, ISSN 1543-8384, 11/2018, Volume 15, Issue 11, pp. 4884 - 4897
Journal Article
Molecular and Cellular Endocrinology, ISSN 0303-7207, 02/2018, Volume 461, p. 215
Genome wide association studies revealed single nucleotide polymorphisms (SNP) located within the promoter of PDZ domain containing protein 1 (PDZK1) to be... 
Drug resistance in microorganisms | RNA | Genes | Estrogen | Calcifediol | Cystic fibrosis | Genetic transcription | Uric acid | Membrane proteins | Vitamin D | Alfacalcidol | Single nucleotide polymorphisms | Thyroid hormones
Journal Article
ACS Chemical Neuroscience, ISSN 1948-7193, 2019, Volume 10, Issue 7, pp. 3120 - 3131
Methylenedioxymethamphetamine (MDMA; ecstasy) is used recreationally and has been investigated as an adjunct to psychotherapy. Most acute effects of MDMA can... 
pharmacogenetics | serotonin system | MDMA | POSTTRAUMATIC-STRESS-DISORDER | FUNCTIONAL POLYMORPHISM | CHEMISTRY, MEDICINAL | EMOTIONAL EMPATHY | BIOCHEMISTRY & MOLECULAR BIOLOGY | MULTIFACETED EMPATHY | NEUROSCIENCES | 5-HTTLPR POLYMORPHISM | ECSTASY | PHARMACOKINETICS | MOOD DISORDERS | 3,4-METHYLENEDIOXYMETHAMPHETAMINE MDMA | PROMOTER REGION
Journal Article
European Journal of Pharmaceutical Sciences, ISSN 0928-0987, 07/2018, Volume 120, pp. 181 - 190
The protein family of Organic Anion Transporting Polypeptides (OATPs) summarizes various transporters known to facilitate cellular uptake of xenobiotics. One... 
Posttranslational modulation | NHERF | PDZK1 | PDZ-domain | Transporter | OATP2B1 | Sulfates | Analysis | Liver | Membrane proteins | Index Medicus
Journal Article
Molecular Human Reproduction, ISSN 1360-9947, 04/2013, Volume 19, Issue 4, pp. 227 - 236
Journal Article
ACS chemical neuroscience, 12/2018
Methylenedioxymethamphetamine (MDMA; ecstasy) is used recreationally and has been investigated as an adjunct to psychotherapy. Most acute effects of MDMA can... 
Journal Article
British journal of clinical pharmacology, 12/2018
The anthelminthic ivermectin is receiving new attention as it is being repurposed for new indications such as mass drug administrations for the treatment of... 
Journal Article
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