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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2011, Volume 108, Issue 49, pp. 19725 - 19730
Acute myocardial infarction (AMI) initiates an intense inflammatory response that promotes cardiac dysfunction, cell death, and ventricular remodeling. The... 
Heart | Myocardial infarction | Granulation tissue | Receptors | Ischemia | Cell death | Myocardium | Small interfering RNA | Renovations | Endothelial cells | NLRP3 | Interleukin-1 | Pyroptosis | NALP3 | EXTRACELLULAR ATP | CELLS | interleukin-1 | CASPASE-1 | MULTIDISCIPLINARY SCIENCES | HEART-FAILURE | RECEPTOR | pyroptosis | RESPONSES | DANGER SIGNALS | IN-VIVO | LIPOPOLYSACCHARIDE | Myocardial Infarction - genetics | Inflammasomes - metabolism | Apoptosis - drug effects | Cytoskeletal Proteins - genetics | NLR Family, Pyrin Domain-Containing 3 Protein | Caspase 1 - metabolism | Male | Myocardial Infarction - diagnostic imaging | Receptors, Purinergic P2X7 - genetics | Ventricular Remodeling | RNA Interference | Cytoskeletal Proteins - metabolism | Pyridoxal Phosphate - analogs & derivatives | Disease Models, Animal | Cell Line | Gene Expression | Echocardiography | Pyridoxal Phosphate - pharmacology | Myocardial Infarction - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Inflammasomes - genetics | Carrier Proteins - genetics | Myocytes, Cardiac - pathology | Animals | Apoptosis Regulatory Proteins | Carrier Proteins - metabolism | Myocytes, Cardiac - drug effects | Caspase 1 - genetics | CARD Signaling Adaptor Proteins | Fluorescent Antibody Technique | Lipopolysaccharides - pharmacology | Myocytes, Cardiac - metabolism | Receptors, Purinergic P2X7 - metabolism | Mice | Oligomers | Care and treatment | Heart cells | Physiological aspects | Development and progression | Health aspects | Heart attack | Biological Sciences
Journal Article
Circulation, ISSN 0009-7322, 11/2018, Volume 138, Issue Suppl_1 Suppl 1, pp. A10771 - A10771
IntroductionDonation after circulatory death (DCD) donors can expand the donor pool for heart transplantation, which presently depends on brain death (DBD)... 
Journal Article
PLoS One, ISSN 1932-6203, 2012, Volume 7, Issue 3, p. e33438
BACKGROUND: Heart failure (HF) is a complex clinical syndrome characterized by impaired cardiac function and poor exercise tolerance. Enhanced inflammation is... 
STATEMENT | CAPACITY | THERAPY | PERFORMANCE | MULTIDISCIPLINARY SCIENCES | ACUTE MYOCARDIAL-INFARCTION | MICE | ECHOCARDIOGRAPHY | ANAKINRA | BETA-ADRENERGIC RESPONSIVENESS | LEFT-VENTRICULAR FUNCTION | Humans | Middle Aged | Myocardial Contraction - physiology | Myocardial Contraction - drug effects | Male | Exercise Tolerance - drug effects | Exercise Test | C-Reactive Protein - metabolism | Adult | Female | Interleukin 1 Receptor Antagonist Protein - pharmacology | Cytokines - blood | Disease Models, Animal | Interleukin-1beta - antagonists & inhibitors | Interleukin-1beta - physiology | Heart Failure, Systolic - drug therapy | Inflammation Mediators - blood | Ventricular Dysfunction, Left - etiology | Biomarkers - blood | Mice, Inbred ICR | Recombinant Proteins - administration & dosage | Ventricular Dysfunction, Left - physiopathology | Animals | Interleukin-1beta - administration & dosage | Ventricular Dysfunction, Left - drug therapy | Oxygen Consumption - drug effects | Exercise Tolerance - physiology | Heart Failure, Systolic - physiopathology | Mice | Heart failure | Heart | Development and progression | Inflammation | Interleukins | Heart attacks | Working groups | Interleukin | Isoproterenol | Epidemiology | Beta blockers | Reduction | Efficiency | Interleukin 1 | Pretreatment | Drug therapy | Cardiology | Heart diseases | Drug dosages | Physical therapy | Medical research | Task forces | Cytokines | Medicare | Internal medicine | Interleukin 1 receptor antagonist | Oxygen consumption | Pharmacology | Interdisciplinary aspects | Patients | Disease prevention | Intolerance | Signaling | Physical fitness | Exercise physiology | Councils | Pharmacy | Flow velocity | Rehabilitation | Ventricle
Journal Article
American Journal of Cardiology, The, ISSN 0002-9149, 2013, Volume 112, Issue 7, pp. 1005 - 1012
Journal Article
EXPERIMENTAL PHYSIOLOGY, ISSN 0958-0670, 03/2013, Volume 98, Issue 3, pp. 734 - 745
New Findings center dot What is the central question of this study? The formation of the cryopyrin inflammasome in the heart induces an intense inflammatory... 
APOPTOSIS | PHYSIOLOGY | ARTERY-OCCLUSION | CARDIOVASCULAR EVENTS | HEART-FAILURE | PREVENTION | MICE | ECHOCARDIOGRAPHY | PHARMACOLOGICAL INHIBITION | NEUTRALIZATION | MODULATION | Interleukins | Heart attack
Journal Article
Journal Article
Radiation Research, ISSN 0033-7587, 11/2016, Volume 186, Issue 5, pp. 478 - 488
There is an ongoing and significant need for radiation countermeasures to reduce morbidities and mortalities associated with exposure of the heart and lungs... 
TGF-BETA | MYOCARDIAL-INFARCTION | LUNG INJURY | INDUCED CARDIOMYOPATHY | FACTOR-ALPHA | HEART | BIOPHYSICS | INDUCED PULMONARY-FIBROSIS | SIGNALING PATHWAY | BIOLOGY | ANIMAL-MODELS | THORACIC IRRADIATION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Radiation-Protective Agents - pharmacokinetics | Half-Life | Male | Cardiomyopathies - etiology | Radiation Injuries, Experimental - etiology | Radiation Injuries, Experimental - drug therapy | Myocardium - metabolism | Respiration - drug effects | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Radiation-Protective Agents - pharmacology | Female | Lung - radiation effects | Lung - metabolism | Signal Transduction - radiation effects | Radiation Injuries, Experimental - metabolism | Cardiomyopathies - drug therapy | Cardiomyopathies - pathology | Respiration - radiation effects | Radiation Injuries, Experimental - pathology | Collagen - metabolism | Animals | Receptors, Transforming Growth Factor beta - antagonists & inhibitors | Signal Transduction - drug effects | Cardiomyopathies - metabolism | Lung - drug effects | Survival Analysis | Radiation-Protective Agents - therapeutic use | Mice | Transforming Growth Factor beta - metabolism | Development and progression | Care and treatment | Enzyme inhibitors | Health aspects | Lung diseases | Radiation effects | Mortality | Fibrosis | Irradiation | Countermeasures | Exposure | Thorax | Survival
Journal Article
Journal of Cardiovascular Pharmacology, ISSN 0160-2446, 09/2019, Volume 74, Issue 3, pp. 175 - 187
Acute myocardial infarction (AMI) is associated with the induction of a sterile inflammatory response that leads to further injury. The NACHT, leucine-rich... 
Journal Article
Circulation, ISSN 0009-7322, 11/2018, Volume 138, Issue Suppl_1 Suppl 1, pp. A11488 - A11488
IntroductionLow dose angiotensin II (ATII) infusion promotes the development of a heart failure with preserved ejection fraction (HFpEF) in the mouse,... 
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 11/2017, Volume 112, pp. 150 - 150
Journal Article