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1. Full Text Tumor MicroRNA expression profiling identifies circulating MicroRNAs for early breast cancer detection
by Matamala, Nerea and Vargas, María Teresa and González-Cámpora, Ricardo and Miñambres, Rebeca and Arias, JoséIgnacio and Menéndez, Primitiva and Andrés-León, Eduardo and Mez-López, Gonzalo Gómez and Yanowsky, Kira and Calvete-Candenas, Julio and Inglada-Pérez, Lucía and Martínez-Delgado, Beatriz and Benítez, Javier
Clinical Chemistry, ISSN 0009-9147, 08/2015, Volume 61, Issue 8, pp. 1098 - 1106
BACKGROUND: The identification of novel biomarkers for early breast cancer detection would be a great advance. Because of their role in tumorigenesis and... 
MAMMOGRAPHY | BIOMARKERS | CELLS | SUPPRESSOR | SOLID TUMORS | RECOGNITION | GENE-EXPRESSION | MARKERS | SERUM | MEDICAL LABORATORY TECHNOLOGY | CLINICAL-SIGNIFICANCE | Reproducibility of Results | Breast Neoplasms - genetics | Oligonucleotide Array Sequence Analysis | Breast Neoplasms - pathology | Early Detection of Cancer | Humans | Gene Expression Regulation, Neoplastic | Female | Reference Values | Biomarkers, Tumor - genetics | MicroRNAs - blood | MicroRNAs - genetics | MicroRNA | Analysis | Breast cancer | Genetic aspects | Diagnosis | Risk factors | Cancer | Antigens | Medical research | Plasma | Funding | Mortality | Mammography | Gene expression | Cancer therapies | Studies | Womens health | Surgery | Medical prognosis | MicroRNAs | Biomarkers | Tumors
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2. Full Text Glycosuria and hyperglycemia in the neonatal period as the first clinical sign of Fanconi‐Bickel syndrome
by Bahíllo‐Curieses, María Pilar and Garrote‐Molpeceres, Rebeca and Miñambres‐Rodríguez, María and del Real‐Llorente, M Rosa and Tobar‐Mideros, Cristina and Rellán‐Rodríguez, Sara
Pediatric Diabetes, ISSN 1399-543X, 02/2018, Volume 19, Issue 1, pp. 180 - 183
Fanconi‐Bickel syndrome is a rare inherited disease characterized by the combination of hepatorenal glycogen accumulation, proximal renal tubular dysfunction... 
hyperglycemia | hepatomegaly | renal tubular dysfunction | fasting hypoglycemia | inherited | GLUT2 | MUTATION | ENDOCRINOLOGY & METABOLISM | PEDIATRICS | SLC2A2 GENE | Infants (Newborn) | Hyperglycemia | Vitamin D | Blood sugar monitoring | Glycogen | Calcifediol | Alfacalcidol | Neonates | Alkaline phosphatase | Renal function | Kidneys | Dietary supplements | Glucose | Hypoglycemia | Calcium phosphates | Bicarbonate | Rickets | Diagnosis | Galactose | Milk
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3. Full Text In Search of ‘Omics'-Based Biomarkers to Predict Risk of Frailty and Its Consequences in Older Individuals: The FRAILOMIC Initiative
by Erusalimsky, Jorge D and Grillari, Johannes and Grune, Tilman and Jansen-Duerr, Pidder and Lippi, Giuseppe and Sinclair, Alan J and Tegnér, Jesper and Viña, Jose and Durrance-Bagale, Anna and Miñambres, Rebeca and Viegas, Marcelo and Rodríguez-Mañas, Leocadio and FRAILOMIC Consortium and on behalf of the FRAILOMIC Consortium
Gerontology, ISSN 0304-324X, 02/2016, Volume 62, Issue 2, pp. 182 - 190
An increase in the number of older people experiencing disability and dependence is a critical aspect of the demographic change that will emerge within Europe... 
Experimental Section / Viewpoint | Disability | Biomarkers | Frailty | Senescence | FRAILOMIC Initiative | Omics | POPULATION | ASSOCIATIONS | ADULTS | PREVENTION | PREVALENCE | TOLEDO | GERIATRICS & GERONTOLOGY | CARDIOVASCULAR-DISEASE | PEOPLE | Biomarkers - metabolism | Prognosis | Risk Assessment | Europe | Genomics | Humans | Proteomics | Aged, 80 and over | Aged | Frail Elderly | Gene Expression Profiling | Aging - metabolism | Demographics | Older people
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4. Full Text MicroRNA deregulation in triple negative breast cancer reveals a role of miR-498 in regulating BRCA1 expression
by Matamala, Nerea and Vargas, Maria Teresa and González-Cámpora, Ricardo and Arias, Jose Ignacio and Menéndez, Primitiva and Andrés-León, Eduardo and Yanowsky, Kira and Llaneza-Folgueras, Ana and Miñambres, Rebeca and Martínez-Delgado, Beatriz and Benítez, Javier
Oncotarget, ISSN 1949-2553, 04/2016, Volume 7, Issue 15, pp. 20068 - 20079
Emerging evidence suggests that BRCA1 pathway contributes to the behavior of sporadic triple negative breast cancer (TNBC), but little is known about the... 
Triple negative breast cancer | MicroRNA | BRCA1 | Cell Proliferation | Humans | Cells, Cultured | Gene Expression Regulation, Neoplastic | Case-Control Studies | BRCA1 Protein - genetics | Triple Negative Breast Neoplasms - genetics | Triple Negative Breast Neoplasms - metabolism | BRCA1 Protein - metabolism | Triple Negative Breast Neoplasms - pathology | Female | Biomarkers, Tumor - genetics | MicroRNAs - genetics | Apoptosis
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5. Full Text RhoE interferes with Rb inactivation and regulates the proliferation and survival of the U87 human glioblastoma cell line
by Poch, Enric and Miñambres, Rebeca and Mocholí, Enric and Ivorra, Carmen and Pérez-Aragó, Amparo and Guerri, Consuelo and Pérez-Roger, Ignacio and Guasch, Rosa M
Experimental Cell Research, ISSN 0014-4827, 2007, Volume 313, Issue 4, pp. 719 - 731
Rho GTPases are important regulators of actin cytoskeleton, but they are also involved in cell proliferation, transformation and oncogenesis. One of this... 
Retinoblastoma protein | RhoE | Proliferation | Cyclin D1 | Apoptosis | ERK | retinoblastoma protein | D1 EXPRESSION | PROTEIN | proliferation | RAS | GENE-EXPRESSION PATTERNS | ROCK-I | apoptosis | G1 PHASE | CELL BIOLOGY | CYCLIN-DEPENDENT KINASES | GTPASES | ONCOLOGY | PROSTATE-CANCER | cyclin D1 | G PHASE | Cyclin D1 - metabolism | Cell Proliferation | Cell Survival | rho GTP-Binding Proteins - genetics | Humans | Retinoblastoma Protein - metabolism | Actin Cytoskeleton - chemistry | Apoptosis - genetics | rho GTP-Binding Proteins - physiology | Transfection | Glioblastoma - genetics | Glioblastoma - pathology | Cell Line, Tumor | Glioblastoma - metabolism | Cytoskeleton - chemistry | Oncology | Cellular biology | Molecular biology | Brain cancer | GLIOMAS | APOPTOSIS | LARGE INTESTINE | ACTIN | MICROTUBULES | PHOSPHORYLATION | CELL PROLIFERATION | MELANOMAS | TUMOR CELLS | 60 APPLIED LIFE SCIENCES | ADENOVIRUS
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6. Full Text The RhoA/ROCK-I/MLC pathway is involved in the ethanol-induced apoptosis by anoikis in astrocytes
by Miñambres, Rebeca and Guasch, Rosa M and Perez-Aragó, Amparo and Guerri, Consuelo
Journal of Cell Science, ISSN 0021-9533, 01/2006, Volume 119, Issue 2, pp. 271 - 282
Anoikis is a programmed cell death induced by loss of anchorage that is involved in tissue homeostasis and disease. Ethanol is an important teratogen that... 
Anoikis | Ethanol | Blebbing | Astrocytes | RhoA | ROCK-1 | SIGNALING PATHWAYS | blebbing | ROCK-I | BRAIN-DEVELOPMENT | ethanol | LIGHT-CHAIN PHOSPHORYLATION | FOCAL ADHESIONS | CELL BIOLOGY | BINDING PROTEIN RHO | anoikis | ACTIN STRESS FIBERS | NEURAL STEM-CELLS | EPITHELIAL-CELLS | ENDOTHELIAL-CELLS | astrocytes | MYOSIN PHOSPHATASE | Astrocytes - cytology | Astrocytes - drug effects | Myosin Light Chains - genetics | Actins - metabolism | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Intracellular Signaling Peptides and Proteins | Rats | rhoA GTP-Binding Protein - metabolism | rhoA GTP-Binding Protein - genetics | Astrocytes - physiology | Ethanol - pharmacology | Animals | Caspases - metabolism | Cell Shape | rho-Associated Kinases | Caspase 3 | Anoikis - drug effects | Myosins - metabolism | Anoikis - physiology | Myosin Light Chains - metabolism | Enzyme Activation | Protein-Serine-Threonine Kinases - metabolism
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7. Full Text The application of cognitive computing technology in genomics in precision oncological medicine: The Sistemas Genomicos Experience
by Pérez, Lucía and Cantalapiedra, Diego and Valero-Hervas, Diana and Duran, Ignacio and Calvete, Oriol and Wang, Ching-Kun and Martinez-Laperche, Carolina and Gonzalez-Neira, Anna and Felipe-Ponce, Vanesa and Lois Olmo, Sergio and Garcia, Jaime and Collado Mico, Carmen and Fernandez Pedrosa, Victoria and Miñambres, Rebeca and Buño Borde, Ismael and Santillan, Sonia and Urman, Alexandra and Suarez Saiz, Fernando Jose and Moya, Christian Martin
Journal of Clinical Oncology, ISSN 0732-183X, 05/2018, Volume 36, Issue 15_suppl, pp. e18544 - e18544
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8. Full Text Glycosuria and hyperglycemia in the neonatal period as the first clinical sign of Fanconi-Bickel syndrome
: Bahíllo-Curieseset al
by Bahíllo-Curieses, María Pilar and Garrote-Molpeceres, Rebeca and Miñambres-Rodríguez, María and del Real-Llorente, M Rosa and Tobar-Mideros, Cristina and Rellán-Rodríguez, Sara
Pediatric Diabetes, ISSN 1399-543X, 02/2018, Volume 19, Issue 1, pp. 180 - 183
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9. Full Text RhoE participates in the stimulation of the inflammatory response induced by ethanol in astrocytes
by Guasch, Rosa M and Blanco, Ana M and Pérez-Aragó, Amparo and Miñambres, Rebeca and Talens-Visconti, Raquel and Peris, Blanca and Guerri, Consuelo
Experimental Cell Research, ISSN 0014-4827, 2007, Volume 313, Issue 17, pp. 3779 - 3788
Astroglial cells are involved in the neuropathogenesis of several inflammatory diseases of the brain, where the activation of inflammatory mediators and... 
Inflammation | RhoE/Rnd3 | Astrocyte | Ethanol | ROCK-I | ethanol | CELL-DEATH | FAMILY | CELL BIOLOGY | GTPASES | ONCOLOGY | inflammation | PATHWAY | CULTURED ASTROCYTES | ACTIN CYTOSKELETON | INTERLEUKIN-1 RECEPTOR | astrocyte | BRAIN | INNATE IMMUNITY | Astrocytes - drug effects | Encephalitis - enzymology | Ethanol - toxicity | rho GTP-Binding Proteins - genetics | Actins - metabolism | Maleimides - pharmacology | rac GTP-Binding Proteins - deficiency | Encephalitis - pathology | Rats | Protein Kinase C - antagonists & inhibitors | Astrocytes - enzymology | rho GTP-Binding Proteins - physiology | Astrocytes - ultrastructure | Animals | Transfection | Cytoskeleton - metabolism | Cytoskeletal Proteins - metabolism | Indoles - pharmacology | Encephalitis - chemically induced | rho-Associated Kinases - deficiency | rhoA GTP-Binding Protein - deficiency | Alcohol | Alcohol, Denatured | Brain | Biomedical research | Cellular biology | Cytokines | Inflammatory diseases
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10. Full Text Diversity in sequences, post-translational modifications and expected pharmacological activities of toxins from four Conus species revealed by the combination of cutting-edge proteomics, transcriptomics and bioinformatics
by Degueldre, Michel and Verdenaud, Marion and Legarda, Garikoitz and Minambres, Rebeca and Zuniga, Sheila and Leblanc, Mathieu and Gilles, Nicolas and Ducancel, Frederic and De Pauw, Edwin and Quinton, Loic
Toxicon, ISSN 0041-0101, 05/2017, Volume 130, pp. 116 - 125
Venomous animals have developed a huge arsenal of reticulated peptides for defense and predation. Based on various scaffolds, they represent a colossal... 
Venomics | Cone snail | Transcriptomics | Bioinformatics | Proteomics | Diversity | CONOSERVER | CONTRYPHAN | INTERROGATION | CONOTOXIN | VENOM DUCT | PEPTIDE | CONOPEPTIDES | ION-CHANNEL | SUPERFAMILY | PHARMACOLOGY & PHARMACY | TOXICOLOGY | RECEPTORS | Mollusk Venoms - pharmacology | Computational Biology - methods | Gene Expression Profiling | Phylogeny | Tandem Mass Spectrometry | Animals | Sequence Analysis, RNA | Mollusk Venoms - metabolism | Protein Isoforms | Chromatography, Liquid | Conus Snail - metabolism | Mollusk Venoms - chemistry | Protein Processing, Post-Translational | Proteomics - methods | Peptides | Mass spectrometry | Computational biology | Venom | Index Medicus
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11. The RhoA/ROCK-I/MLC pathway is involved in the ethanol-induced apoptosis by anoikis in astrocytes
by Minambres, Rebeca and Guasch, Rosa M and Perez-Arago, Amparo and Guerri, Consuelo
Journal of Cell Science, ISSN 0021-9533, 01/2006, Volume 119, Issue 2, pp. 271 - 282
Anoikis is a programmed cell death induced by loss of anchorage that is involved in tissue homeostasis and disease. Ethanol is an important teratogen that... 
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12. Full Text Molecular characterization and recuperation of bacteriocins produced by lactic acid bacteria isolated from dry cured-meat products
by Miñambres, Rebeca and Rodrigo, Alejandro and Villa-Carvajal, Mercedes and García-Reverter, José and Tomás, David
Journal of Biotechnology, ISSN 0168-1656, 2007, Volume 131, Issue 2, pp. S235 - S235
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13. Full Text DIAGNÓSTICO MOLECULAR DE ENFERMEDADES GENÉTICAS: DEL DIAGNÓSTICO GENÉTICO AL DIAGNÓSTICO GENÓMICO CON LA SECUENCIACIÓN MASIVA
by Sonia Santillán-Garzón Md., PhD and Dan Diego-Álvarez, PhD and Celia Buades, PhD and Alejandro Romera-López, PhD and Lucía Pérez-Cabornero, PhD and Diana Valero-Hervás, PhD and Diego Cantalapiedra, HGBSC and Bioinformatics, MSc and Vanesa Felipe-Ponce and Gracia Hernández-Poveda and María José Roca and Clara Casañs and Victoria Fernández-Pedrosa, PhD and Carmen Collado M and Ángela Arilla C and Juan Carlos Triviño P and Óscar RodrÍguez C and Guillermo Marco and Mayte Gil, PhD and Rebeca Miñambres, PhD and Alida Ballester, PhD
Revista Médica Clínica Las Condes, ISSN 0716-8640, 07/2015, Volume 26, Issue 4, pp. 458 - 469
En la actualidad se conocen 8.000 enfermedades genéticas monogénicas. La mayoría de ellas son heterogéneas, por lo que el diagnóstico molecular por técnicas... 
análisis de metilación | diagnóstico molecular genómico | genoma | paneles de genes | exoma | Enfermedades genéticas heterogéneas | Secuenciación Sanger | análisis de fragmentos | secuenciación masiva | arrays de hibridación genómica comparada | diagnóstico molecular genético | amplificación múltiple de sondas dependientes de ligación
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