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Nature Immunology, ISSN 1529-2908, 04/2011, Volume 12, Issue 4, pp. 304 - 311
Journal Article
Nature Immunology, ISSN 1529-2908, 2013, Volume 14, Issue 11, pp. 1155 - 1165
Journal Article
Cell Death and Differentiation, ISSN 1350-9047, 03/2017, Volume 24, Issue 3, pp. 481 - 491
Peptido-mimetic inhibitor of apoptosis protein (IAP) antagonists (Smac mimetics (SMs)) can kill tumour cells by depleting endogenous IAPs and thereby inducing... 
TUMOR-NECROSIS-FACTOR | INTERFERON-GAMMA | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | ALPHA-DEPENDENT APOPTOSIS | RECEPTOR | FAS-MEDIATED APOPTOSIS | TNF-ALPHA | NF-KAPPA-B | SIGNALING COMPLEXES | EXPRESSION | CELL BIOLOGY | Protein Kinases - metabolism | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Caspase Inhibitors - pharmacology | Apoptosis - drug effects | Humans | Caspase 8 - metabolism | Caspase 8 - chemistry | Cytokine TWEAK - pharmacology | Interferon-gamma - metabolism | Receptors, Tumor Necrosis Factor, Type I - metabolism | Recombinant Proteins - biosynthesis | Caspase 8 - genetics | Recombinant Proteins - isolation & purification | Receptors, Tumor Necrosis Factor, Type I - deficiency | Inhibitor of Apoptosis Proteins - antagonists & inhibitors | Pentanoic Acids - pharmacology | Inhibitor of Apoptosis Proteins - metabolism | Protein Kinases - deficiency | Interferon-gamma - genetics | Cell Line | Caspase 10 - metabolism | Recombinant Proteins - pharmacology | Receptors, Tumor Necrosis Factor, Type I - genetics | CRISPR-Cas Systems - genetics | Mice, Knockout | Drug Synergism | HT29 Cells | Receptor-Interacting Protein Serine-Threonine Kinases - genetics | Animals | Caspase 10 - genetics | Caspase 10 - chemistry | Mice | Receptor-Interacting Protein Serine-Threonine Kinases - deficiency | Interferon-gamma - pharmacology | Index Medicus | Original Paper
Journal Article
Nature Cell Biology, ISSN 1465-7392, 11/2008, Volume 10, Issue 11, pp. 1309 - 1317
The covalent attachment of ubiquitin to target proteins influences various cellular processes, including DNA repair, NF-κB signalling and cell survival. The... 
UBA DOMAIN | ACTIVATION | SIGNALING PATHWAY | STRUCTURAL BASIS | ALPHA-DEPENDENT APOPTOSIS | LINKED INHIBITOR | XIAP | PROTEIN LIGASE | BCL10 | MALT LYMPHOMA | CELL BIOLOGY
Journal Article
Cell Death and Differentiation, ISSN 1350-9047, 03/2017, Volume 24, Issue 3, p. 481
  Peptido-mimetic inhibitor of apoptosis protein (IAP) antagonists (Smac mimetics (SMs)) can kill tumour cells by depleting endogenous IAPs and thereby... 
Journal Article
Current Cancer Drug Targets, ISSN 1568-0096, 03/2008, Volume 8, Issue 2, pp. 118 - 123
Ubiquitylation is an essential cellular process, and yet many cancer cells appear to be more reliant upon it than normal cells as they are surprisingly... 
MULTIPLE-MYELOMA | MDM2-DEFICIENT MICE | ONCOLOGY | UBIQUITIN-PROTEIN LIGASE | MYELOMA CELLS | SQUAMOUS-CELL CARCINOMA | TUMOR-SUPPRESSOR | EMBRYONIC LETHALITY | NF-KAPPA-B | PROTEASOME INHIBITORS | BH3-ONLY PROTEINS
Journal Article
Nature Cell Biology, ISSN 1465-7392, 11/2008, Volume 10, Issue 11, pp. 1309 - 1317
  The covalent attachment of ubiquitin to target proteins influences various cellular processes, including DNA repair, NF-kappaB signalling and cell survival.... 
Ubiquitin | Control | Genetic aspects | Cellular signal transduction | Research | Carcinogenesis | Health aspects
Journal Article
Current Biology, ISSN 0960-9822, 2009, Volume 19, Issue 1, pp. R15 - R17
TNFα can activate pathways leading to caspase-8-mediated apoptosis, as well as inflammatory pathways signaled by transcription factors. The adaptor protein... 
APOPTOSIS | ACTIVATION | C-IAP1 | UBIQUITIN LIGASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | DEGRADATION | MICE | CIAP1 | RIP1 | CELL-DEATH | Proteins | Ubiquitin-Protein Ligases | Life Sciences | Animals | Apoptosis Regulatory Proteins | NF-kappa B | GTPase-Activating Proteins | Mice | Development Biology | Tumor Necrosis Factor-alpha | Cell Cycle Proteins | Mice, Knockout
Journal Article
Current cancer drug targets, 03/2008, Volume 8, Issue 2, p. 118
Journal Article
Journal Article
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