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Nature, ISSN 0028-0836, 2014, Volume 511, Issue 7508, pp. 184 - 190
Journal Article
Science, ISSN 0036-8075, 9/2010, Volume 329, Issue 5997, pp. 1345 - 1348
Although practiced clinically for more than 40 years, the use of hematopoietic stem cell (HSC) transplants remains limited by the ability to expand these cells... 
Hep G2 cells | Cytokines | REPORTS | Stem cells | Multipotent stem cells | Bone marrow | Cultured cells | Transplantation | Aryl hydrocarbon receptors | Hematopoietic stem cells | Blood | EX-VIVO EXPANSION | ENGRAFTMENT | MULTIDISCIPLINARY SCIENCES | BONE-MARROW | BIOLOGY | MICE | UMBILICAL-CORD BLOOD | BINDING | TRANSPLANTATION | Antigens, CD34 - analysis | Cell Proliferation | Receptors, Aryl Hydrocarbon - antagonists & inhibitors | Species Specificity | Cell Count | Humans | Aryl Hydrocarbon Hydroxylases - genetics | Antigens, CD - analysis | Multipotent Stem Cells - drug effects | Hematopoiesis | Polychlorinated Dibenzodioxins - pharmacology | Hematopoietic Stem Cells - physiology | Receptors, Aryl Hydrocarbon - metabolism | Multipotent Stem Cells - physiology | Hematopoietic Stem Cells - drug effects | Signal Transduction | Purines - metabolism | Purines - pharmacology | Cells, Cultured | Hematopoietic Stem Cell Transplantation | Hematopoietic Stem Cells - metabolism | Mice, SCID | AC133 Antigen | Aryl Hydrocarbon Hydroxylases - metabolism | Cell Lineage | Animals | Multipotent Stem Cells - cytology | Small Molecule Libraries | Hematopoietic Stem Cells - cytology | Cytochrome P-450 CYP1B1 | Mice, Inbred NOD | Mice | Glycoproteins - analysis | Cytokines - pharmacology | Peptides - analysis | Physiological aspects | Arylation | Human | Receptors | Aromatic compounds | Modulation | Hydrocarbons | Derivatives | Culture | Index Medicus
Journal Article
Environmental Science and Technology, ISSN 0013-936X, 12/2015, Volume 49, Issue 24, pp. 14614 - 14624
Journal Article
Environmental Health Perspectives, ISSN 0091-6765, 9/2008, Volume 116, Issue 9, pp. 1203 - 1210
Background: Concerns have been raised about the biological and toxicologic effects of the anti-microbials triclocarban (TCC) and triclosan (TCS) in personal... 
Testosterone | Receptors | Bioassay | Antimicrobials | Cell lines | Environmental health | Reporter genes | Carbanilides | Transitional cell carcinoma | Research | Gene expression | Antimicrobial | Aryl hydrocarbon receptor | Estrogen receptor | Carbanilide analog | Androgen receptor | Ryanodine receptor | Bioactivity | Sensitization | Triclosan | Signal amplification | Triclocarbon | carbanilide analog | antimicrobial | PERSONAL CARE PRODUCTS | MECHANISM | estrogen receptor | signal amplification | triclosan | RECOMBINANT CELL BIOASSAYS | IDENTIFICATION | triclocarban | aryl hydrocarbon receptor | BREAST-CANCER | ENVIRONMENTAL SCIENCES | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | androgen receptor | bioactivity | CHEMICALS | WASTE-WATER | RYANODINE RECEPTORS | ESTROGEN | ryanodine receptor | sensitization | Animals | Receptors, Cell Surface - drug effects | Humans | Carbanilides - pharmacology | Models, Molecular | Biological Assay | Anti-Bacterial Agents - pharmacology | Triclosan - pharmacology | Tumor Cells, Cultured | In Vitro Techniques | Triclocarban | Drugs | Measurement | Biological assay | Health aspects | Methods | Index Medicus | Binding | Human | Calcium | Health | Estrogens | Hydrocarbons | In vitro testing | Activation | Biological | Screens | Analogs | Elevation | Animal health | Aromatic compounds | Copyrights | Bills
Journal Article
Environmental Toxicology and Chemistry, ISSN 0730-7268, 02/2018, Volume 37, Issue 2, pp. 385 - 397
Developed relative potency factors for VM7luc4E2 transactivation assay in the present study were used in mass‐balance analysis to investigate estrogenic... 
Relative potency | Metabolite | Estrogen receptor–mediated activity | VM7Luc4E2 transactivation assay | Mass‐balance analysis | Mass-balance analysis | ASSAY | Estrogen receptor-mediated activity | RECEPTOR-ALPHA | REPORTER | ESTROGENIC/ANTIESTROGENIC ACTIVITIES | ENVIRONMENTAL SCIENCES | CELL BIOASSAYS | ENDOCRINE DISRUPTORS | GENE-EXPRESSION | H4IIE-LUC BIOASSAY | RIVER SEDIMENTS | TOXICOLOGY | MCF-7 CELLS | Estradiol - analogs & derivatives | Luciferases - metabolism | Polycyclic Aromatic Hydrocarbons - toxicity | Humans | Metabolome | Estrogens - toxicity | Cytochrome P-450 CYP1A1 - metabolism | Fulvestrant | Soil Pollutants - toxicity | Animals | Estradiol - toxicity | Polycyclic Aromatic Hydrocarbons - metabolism | Polycyclic Aromatic Hydrocarbons - analysis | Soil - chemistry | Benzoflavones - toxicity | Cell Line, Tumor | Methylation | Acridine | Chemical analysis | Estrogens | Bioassays | Cytochrome P450 | Estrogen | Soil investigations | Estrogen receptors | Sediment pollution | Industrial areas | Alkylation | Inhibitors | Xenoestrogens | Metabolites | Polycyclic aromatic hydrocarbons | Aromatic compounds | Soil analysis | Naphthoflavone | Estrogenic activity | Soil contamination | Index Medicus | Miljövetenskap | Naturvetenskap | Estrogen receptor–mediated activity; Relative potency; Metabolite; VM7Luc4E2 transactivation assay; Mass-balance analysis | Natural Sciences | Earth and Related Environmental Sciences | Environmental Sciences | Geovetenskap och miljövetenskap
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 09/2018, Volume 19, Issue 9, p. 2692
The aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor that modulates gene expression following its binding and activation by... 
TCDD | Ah receptor | In silico | AhR | Indirubin | In vitro | ACTIVATION | PROMISCUITY | DNA RECOGNITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | DIOXIN RECEPTOR | in silico | SITE-DIRECTED MUTAGENESIS | CHEMISTRY, MULTIDISCIPLINARY | HEAT-SHOCK-PROTEIN | indirubin | ARYL-HYDROCARBON RECEPTOR | in vitro | FUNCTIONAL-ANALYSIS | GENE-EXPRESSION | LIGAND-BINDING DOMAIN | Basic Helix-Loop-Helix Transcription Factors - agonists | Basic Helix-Loop-Helix Transcription Factors - genetics | Mutagenesis, Site-Directed | Protein Structure, Secondary | Species Specificity | Receptors, Aryl Hydrocarbon - chemistry | Humans | Receptors, Aryl Hydrocarbon - genetics | Models, Molecular | Receptors, Aryl Hydrocarbon - agonists | Animals | Basic Helix-Loop-Helix Transcription Factors - metabolism | Polychlorinated Dibenzodioxins - pharmacology | Computer Simulation | Protein Binding - drug effects | Receptors, Aryl Hydrocarbon - metabolism | Indoles - pharmacology | Mice | Molecular Docking Simulation | In Vitro Techniques | Binding Sites | Basic Helix-Loop-Helix Transcription Factors - chemistry | Binding | Residues | Transformation | Animal models | Amino acids | Homology | Functional analysis | Gene expression | Organic chemistry | Molecular modelling | Mutagenesis | Aromatic compounds | Dioxin | Site-directed mutagenesis | Infrared radiation | Docking | Ligands | Transformations | Mutation | Deoxyribonucleic acid--DNA | Hydrocarbons | Proteins | Binding sites | Index Medicus
Journal Article
Journal Article