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Journal of Physical Chemistry B, ISSN 1520-6106, 07/2016, Volume 120, Issue 28, pp. 6939 - 6950
Chaotropes like urea and guanidinium chloride (GdmCl) tend to destabilize, and kosmotropes like proline tend to stabilize folded structures of peptides and... 
HYDROPHOBIC INTERACTIONS | OSMOLYTE | PROTEIN DENATURATION | AQUEOUS GUANIDINIUM CHLORIDE | AMINO-ACIDS | CHEMISTRY, PHYSICAL | FORCE-FIELD | UREA DENATURATION | MOLECULAR-DYNAMICS SIMULATIONS | ANISOTROPY | WATER | Chemical properties | Research | Peptides | Protein folding | Guanidine | Diffusion rate | Solvation | Nata | Proline | Molecular dynamics | Ureas | Mathematical models
Journal Article
Journal of Pharmaceutical Sciences, ISSN 0022-3549, 02/2016, Volume 105, Issue 2, pp. 602 - 612
Biosimilarity assessments are performed to decide whether 2 preparations of complex biomolecules can be considered "highly similar." In this work, a machine... 
Journal Article
Journal of Pharmaceutical Sciences, ISSN 0022-3549, 04/2016, Volume 105, Issue 4, pp. 1444 - 1453
Human fibroblast growth factor-1 (FGF-1) has broad therapeutic potential in regenerative medicine but has undesirable biophysical properties of low... 
Journal Article
Journal of Physical Chemistry B, ISSN 1520-6106, 01/2014, Volume 118, Issue 2, pp. 639 - 647
Journal Article
Journal of Pharmaceutical Sciences, ISSN 0022-3549, 02/2016, Volume 105, Issue 2, pp. 588 - 601
As part of a series of articles in this special issue describing 4 well-defined IgG1-Fc glycoforms as a model system for biosimilarity analysis (high... 
Journal Article
Journal of Pharmaceutical Sciences, ISSN 0022-3549, 02/2016, Volume 105, Issue 2, pp. 559 - 574
Four different well-defined IgG1 Fc glycoforms are proposed as a model system to examine important biological and physicochemical features for protein drug... 
Journal Article