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06/2014, Methods in Molecular Biology Ser., ISBN 9781493908813, Volume 1169
Annotation Innate DNA and RNA Recognition: Method and Protocols presents validated experimental strategies to dissect nucleic acid sensing in-vitro and in-vivo... 
Science | Biology
Web Resource
Structure, ISSN 0969-2126, 09/2017, Volume 25, Issue 9, pp. 1360 - 1370.e4
Journal Article
Methods in molecular biology (Clifton, N.J.), ISSN 1064-3745, 2014, Volume 1169, pp. 77 - 86
Foreign nucleic acids are recognized by germ-line-encoded receptors expressed in immune and nonimmune cells. Activation of the nucleic acid-specific pattern... 
Flow cytometry | Cell death | Annexin | Apoptosis | Necrosis | Receptors, Pattern Recognition - metabolism | Animals | Flow Cytometry | Apoptosis - drug effects | Nucleic Acids - pharmacology | Cells, Cultured | Mice | Cell Death - drug effects | In Vitro Techniques | Index Medicus
Journal Article
Nature Reviews Endocrinology, ISSN 1759-5029, 12/2016, Volume 12, Issue 12, p. 695
  Although β-cell heterogeneity was discovered more than 50 years ago, the underlying principles have been explored only during the past decade. Islet-cell... 
Molecular targeted therapy | Pancreatic beta cells | Innovations | Genetic aspects | Health aspects | Methods | Diabetes therapy
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2014, Volume 1169, p. v
Journal Article
The Journal of Pathology, ISSN 0022-3417, 12/2012, Volume 228, Issue 4, pp. 482 - 494
Journal Article
Diabetes, ISSN 0012-1797, 05/2017, Volume 66, Issue 5, pp. 1247 - 1257
In pancreatic -cells, mitochondrial bioenergetics control glucose-stimulated insulin secretion. Mitochondrial dynamics are generally associated with quality... 
FUSION | BETA-CELL APOPTOSIS | DISEASE | ENDOCRINOLOGY & METABOLISM | DYNAMIN-RELATED PROTEIN-1 | DYSFUNCTION | STRESS | GTPASE | DIVISION | DRP1 | PROTECTS | Dynamins - antagonists & inhibitors | Microtubule-Associated Proteins - genetics | Mitochondrial Dynamics - genetics | Humans | Mitochondrial Proteins - antagonists & inhibitors | Mitochondria - metabolism | Mitochondrial Proteins - genetics | GTP Phosphohydrolases - antagonists & inhibitors | Microtubule-Associated Proteins - antagonists & inhibitors | Mitochondria - pathology | Gene Knockdown Techniques | Microscopy, Confocal | Insulin - metabolism | Insulin-Secreting Cells - metabolism | Animals | Insulin-Secreting Cells - drug effects | GTP Phosphohydrolases - genetics | Islets of Langerhans - metabolism | Adenosine Triphosphate - metabolism | Glucose - metabolism | Mice | Energy Metabolism - genetics | Insulin Secretion | Pyruvic Acid - pharmacology | Energy metabolism | Mitochondrial biogenesis | Research | Bioenergetics | Mitochondria | Phosphorylation | Oxidative phosphorylation | Secretion | Quality control | Pyruvic acid | Glucose | Islets of Langerhans | Pancreas | Insulin | Cells | Index Medicus | Abridged Index Medicus | Clinical Medicine | Medical and Health Sciences | Endokrinologi och diabetes | Klinisk medicin | Medicin och hälsovetenskap | Endocrinology and Diabetes
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 01/2013, Volume 123, Issue 1, pp. 236 - 246
Nephrocalcinosis, acute calcium oxalate (CaOx) nephropathy, and renal stone disease can lead to inflammation and subsequent renal failure, but the underlying... 
KIDNEY-DISEASE | NEPHROLITHIASIS | MEDICINE, RESEARCH & EXPERIMENTAL | DANGER | ACTIVATION | DENDRITIC CELLS | NLRP3 INFLAMMASOME | STONE FORMATION | FAILURE | NEPHROPATHY | NALP3 INFLAMMASOME | Interleukin-18 - immunology | Cytoskeletal Proteins - genetics | NLR Family, Pyrin Domain-Containing 3 Protein | Dendritic Cells - immunology | Nephrocalcinosis - immunology | Receptors, Interleukin-1 - genetics | Interleukin-1beta - genetics | Inflammation - metabolism | Nephrocalcinosis - metabolism | Myeloid Differentiation Factor 88 - immunology | Cytoskeletal Proteins - metabolism | Kidney Tubules - pathology | Immunologic Deficiency Syndromes - immunology | Kidney Tubules - metabolism | Carrier Proteins - immunology | Dendritic Cells - metabolism | Interleukin-1beta - secretion | Kidney Tubules - immunology | Calcium Oxalate - immunology | Receptors, Interleukin-1 - immunology | Myeloid Differentiation Factor 88 - genetics | Interleukin-1beta - immunology | Inflammation - immunology | Calcium Oxalate - metabolism | Mice, Knockout | Receptors, Interleukin-1 - metabolism | Carrier Proteins - genetics | Nephrocalcinosis - pathology | Animals | Apoptosis Regulatory Proteins | Carrier Proteins - metabolism | Cytoskeletal Proteins - immunology | Nephrocalcinosis - genetics | CARD Signaling Adaptor Proteins | Immunologic Deficiency Syndromes - genetics | Immunologic Deficiency Syndromes - metabolism | Inflammation - genetics | Mice | Interleukin-18 - genetics | Myeloid Differentiation Factor 88 - metabolism | Interleukin-18 - metabolism | Phagocytosis | Index Medicus | Abridged Index Medicus
Journal Article
Molecular Metabolism, ISSN 2212-8778, 2015, Volume 4, Issue 5, pp. 365 - 366
Journal Article
The Journal of Pathology, ISSN 0022-3417, 07/2013, Volume 230, Issue 3, pp. 322 - 335
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 5, pp. e20118 - e20118
The long pentraxin PTX3 has multiple roles in innate immunity. For example, PTX3 regulates C1q binding to pathogens and dead cells and regulates their uptake... 
C-REACTIVE PROTEIN | LPR MICE | DENDRITIC CELLS | COMPLEMENT ACTIVATION | APOPTOTIC CELLS | PULMONARY INFLAMMATION | MRL-(FAS)LPR MICE | BIOLOGY | SERUM-AMYLOID-P | PRONE MICE | INNATE IMMUNITY | Antibody Formation - immunology | Lung - pathology | Cell Proliferation | Nerve Tissue Proteins - deficiency | Gene Expression Regulation | Glomerulonephritis - immunology | CD4-Positive T-Lymphocytes - immunology | Lung Diseases - immunology | Nerve Tissue Proteins - metabolism | Autoantibodies - immunology | Mice, Inbred MRL lpr | Animals | B-Lymphocytes - immunology | C-Reactive Protein - metabolism | Glomerulonephritis - pathology | C-Reactive Protein - deficiency | Mice | Lung Diseases - pathology | CD8-Positive T-Lymphocytes - immunology | Lupus Erythematosus, Systemic - pathology | Lung - immunology | Phagocytosis | Apoptosis | Lupus | Autoimmunity | Systemic lupus erythematosus | Autoantibodies | Lung diseases | Development and progression | Kidney diseases | B cells | T cells | Macrophages | Glomerulonephritis | Flow cytometry | Nephritis | Leukocyte migration | Pathogenesis | CD8 antigen | Lung | Hydrocarbons | Innate immunity | Lymphocytes T | Infections | Lupus nephritis | Leukocytes | Immunity | Experiments | Risk factors | Recruitment | Phagocytes | Lymphocytes | Deoxyribonucleic acid--DNA | Pentraxins | Immune system | Kidneys | Cytokines | Dendritic cells | Immunoregulation | Inflammation | CD3 antigen | CD4 antigen | White blood cells | Chronic conditions | Lungs | Mutation | Autoimmune diseases | P-selectin | Peritoneum | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 2016, Volume 535, Issue 7612, pp. 430 - 434
Journal Article
Nature, ISSN 0028-0836, 07/2016, Volume 535, Issue 7612, p. 430
Insulin-dependent diabetes is a complex multifactorial disorder characterized by loss or dysfunction of β-cells. Pancreatic β-cells differ in size, glucose... 
Islands of Langerhans | Physiological aspects | Identification and classification | Cells | Studies | Rodents | Insulin resistance | Glucose | Diabetes | Metabolism | Gene expression | Insulin
Journal Article
by Grilo, Clara and Coimbra, Michely R and Cerqueira, Rafaela C and Barbosa, Priscilla and Dornas, Rubem A. P and Gonçalves, Larissa O and Teixeira, Fernanda Z and Coelho, Igor Pfeifer and Schmidt, Brenda R and Pacheco, Diana L. K and Schuck, Gabriela and Esperando, Isadora B and Anza, Juan A and Beduschi, Júlia and Oliveira, Nicole R and Pinheiro, Paula F and Bager, Alex and Secco, Helio and Guerreiro, Marcello and Carvalho, Carine F and Veloso, Aline C and Custódio, Ana E. I and Marçal, Oswaldo and Ciocheti, Giordano and Assis, Julia and Ribeiro, Milton Cezar and Francisco, Beatriz S. S and Cherem, Jorge J and Trigo, Tatiane C and Jardim, Márcia M. A and Franceschi, Ingridi C and Espinosa, Caroline and Tirelli, Flávia P and Rocha, Vlamir J and Sekiama, Margareth L and Barbosa, Gedimar P and Rossi, Helen R and Moreira, Tainah C and Cervini, Marcelo and Rosa, Clarissa Alves and Silva, Lucas Gonçalves and Ferreira, Claudia M. M and César, Augusto and Casella, Janaina and Mendes, Sérgio L and Zina, Juliana and Bastos, Deivson F. O and Souza, Ricardo A. T and Hartmann, Paulo A and Deffaci, Angela C. G and Mulinari, Jéssica and Luzzi, Siane C and Rezzadori, Tiago and Kolcenti, Cassiane and Reis, Tiago Xavier and Fonseca, Vanessa S. C and Giorgi, Camilo F and Migliorini, Raissa P and Kasper, Carlos Benhur and Bueno, Cecília and Sobanski, Marcela and Pereira, Ana P. F. G and Andrade, Fernanda A. G and Fernandes, Marcus E. B and Corrêa, Luiz L. C and Nepomuceno, Adriana and Banhos, Aureo and Hannibal, Wellington and Fonseca, Rogério and Costa, Lizit A and Medici, Emilia P and Croce, Aline and Werther, Karin and Oliveira, Juliana P and Ribeiro, Julia M and Santi, Mariele and Kawanami, Aline E and Perles, Livia and Couto, Caroline and Figueiró, Daniela S and Eizirik, Eduardo and Correia, Antonio A and Corrêa, Fabio M and Queirolo, Diego and Quagliatto, André L and Saranholi, Bruno H and Galetti, Pedro M and Rodriguez‐Castro, Karen G and Braz, Vivian S and França, Frederico G. R and Buss, Gerson and Rezini, Josias A and Lion, Marília B and Cheida, Carolina C and Lacerda, Ana C. R and Freitas, Carlos Henrique and Venâncio, Fernando and Adania, Cristina H and Batisteli, Augusto F and Hegel, Carla G. Z and ...
Ecology, ISSN 0012-9658, 11/2018, Volume 99, Issue 11, pp. 2625 - 2625
Journal Article