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The New England Journal of Medicine, ISSN 0028-4793, 09/2014, Volume 371, Issue 11, pp. 1005 - 1015
About 25% of young adults with ALL have Ph-like genotypes, which are associated with poor outcomes with conventional treatment. In this gene-expression study,... 
MEDICINE, GENERAL & INTERNAL | MODELS | B-CELL PRECURSOR | INHIBITOR THERAPY | IMATINIB | PEDIATRIC ACUTE LEUKEMIAS | GENE FUSION | EXPRESSION | ETV6-NTRK3 FUSION TRANSCRIPTS | CRLF2 | DELETION | Oligonucleotide Array Sequence Analysis | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Humans | Child, Preschool | Infant | Male | Young Adult | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Heterografts | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - mortality | Adult | Female | DNA, Neoplasm - analysis | Receptors, Cytokine - metabolism | Child | Philadelphia Chromosome | Receptors, Cytokine - genetics | Signal Transduction - genetics | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Animals | Protein Kinase Inhibitors - therapeutic use | Adolescent | Survival Analysis | Mice | Polymorphism, Single Nucleotide | Genome, Human | Protein-Tyrosine Kinases - antagonists & inhibitors | Development and progression | Care and treatment | Genetic aspects | Research | Lymphocytic leukemia | Tyrosine metabolism | Cell proliferation | Adolescence | Tyk2 protein | Leukemia | Genes | Clinical trials | Oncology | Genomes | Kinases | Cell activation | Janus kinase 2 | Xenografts | Teenagers | Children | Protein-tyrosine kinase | Age | Tyrosine | Young adults | Genomic analysis | Acute lymphatic leukemia | Stat5 protein | Lymphatic leukemia | Gene expression | Philadelphia chromosome | Interleukin 7 receptors | Thymic stromal lymphopoietin | Lymphocytes B | Cell lines
Journal Article
Nature, ISSN 0028-0836, 01/2012, Volume 481, Issue 7380, pp. 157 - 163
Journal Article
Nature Genetics, ISSN 1061-4036, 08/2017, Volume 49, Issue 8, pp. 1211 - 1218
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2009, Volume 106, Issue 23, pp. 9414 - 9418
Journal Article
Nature Genetics, ISSN 1061-4036, 03/2013, Volume 45, Issue 3, pp. 242 - 252
The genetic basis of hypodiploid acute lymphoblastic leukemia (ALL), a subtype of ALL characterized by aneuploidy and poor outcome, is unknown. Genomic... 
P53 MUTATIONS | NEUROFIBROMATOSIS TYPE-1 GENE | TRANSMEMBRANE ADAPTER | IKAROS | GENETICS & HEREDITY | JUVENILE MYELOMONOCYTIC LEUKEMIA | REGULATORY T-CELLS | MUTANT P53 | HUMAN CANCERS | HEMATOLOGIC MALIGNANCIES | CHILDHOOD | Humans | Gene Expression Regulation, Neoplastic | Molecular Sequence Data | Aneuploidy | Transplantation, Heterologous | Phosphatidylinositol 3-Kinases - metabolism | Tumor Suppressor Protein p53 - genetics | Ikaros Transcription Factor - genetics | Haploidy | Precursor Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Base Sequence | Ikaros Transcription Factor - metabolism | Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology | Signal Transduction | Retinoblastoma Protein - metabolism | Tumor Suppressor Protein p53 - metabolism | Treatment Outcome | Phosphatidylinositol 3-Kinases - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Animals | Retinoblastoma Protein - genetics | Chromosome Aberrations | Cell Line, Tumor | Mice | Mutation | Care and treatment | Genomics | Physiological aspects | Genetic aspects | Research | Acute lymphocytic leukemia | Cancer | Medical research | Pediatrics | Cloning | Genetics | Genomes | Kinases | Chromosomes | Medicinsk genetik | Basic Medicine | Medical Genetics | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
Nature, ISSN 0028-0836, 11/2016, Volume 539, Issue 7628, pp. 304 - 308
Journal Article
Nature Communications, ISSN 2041-1723, 11/2016, Volume 7, Issue 1, p. 13331
Journal Article