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Journal of Biological Chemistry, ISSN 0021-9258, 11/2013, Volume 288, Issue 46, pp. 32979 - 32990
Journal Article
Cell Death and Differentiation, ISSN 1350-9047, 2019, Volume 26, Issue 10, pp. 1942 - 1954
Journal Article
Journal Article
Journal Article
CANCERS, ISSN 2072-6694, 08/2019, Volume 11, Issue 8, p. 1211
The small GTPase RAC1B functions as a powerful inhibitor of transforming growth factor (TGF)-beta 1-induced epithelial-mesenchymal transition, cell motility,... 
EPITHELIAL-MESENCHYMAL TRANSITION | MIGRATION | TGF-beta | RNA interference | PAR2 | pancreatic carcinoma | ONCOLOGY | RAC1B | cell migration | ALK5 | EMT | TGF-β
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 06/2018, Volume 175, Issue 11, pp. 2063 - 2076
Background and Purpose Previously, we demonstrated that exogenous heat shock protein 27 (HSP27/gene, HSPB1) treatment of human endothelial progenitor cells... 
ARTERIES | CONCISE GUIDE | HYPERPOLARIZING FACTOR | ESTROGEN | ATHEROSCLEROSIS | RELAXATION | PHARMACOLOGY & PHARMACY | HEAT-SHOCK-PROTEIN-27 | EXPRESSION | CELL | VASCULAR SMOOTH-MUSCLE | Receptor, PAR-2 - metabolism | Endothelium, Vascular - drug effects | Male | Receptors, Muscarinic - metabolism | Structure-Activity Relationship | Endothelium, Vascular - enzymology | Dose-Response Relationship, Drug | Quinoxalines - pharmacology | Receptor, PAR-2 - antagonists & inhibitors | Oxadiazoles - pharmacology | Enzyme Inhibitors - chemistry | Female | HSP27 Heat-Shock Proteins - antagonists & inhibitors | Nitric Oxide Synthase Type III - metabolism | Oxadiazoles - chemistry | NG-Nitroarginine Methyl Ester - pharmacology | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Quinoxalines - chemistry | Mice, Knockout | Nitric Oxide Synthase Type III - antagonists & inhibitors | NG-Nitroarginine Methyl Ester - chemistry | Animals | HSP27 Heat-Shock Proteins - metabolism | Mice | Vasodilation - drug effects | Acetylcholine receptors (muscarinic) | Proteinase | Males | Vasodilation | Proteins | Receptors | Synthesis | Rodents | Phenylephrine | Aorta | Vascular endothelial growth factor | Recombinant | Bioassay | Ovariectomy | Secretion | Bioassays | Heat shock proteins | Sex differences | Biological assays | Progenitor cells | Nitric-oxide synthase | Endothelial cells | Sensitivity | Hsp27 protein | Coronary vessels | Nitric oxide | Stem cells | Cells (biology) | Females | Cell migration | Heat shock | Research Papers | Research Paper
Journal Article
Cancer Research, ISSN 0008-5472, 07/2017, Volume 77, Issue 13 Supplement, pp. 2014 - 2014
Journal Article
Cancers, ISSN 2072-6694, 05/2019, Volume 11, Issue 5, p. 691
The small GTPase Ras-related C3 botulinum toxin substrate 1B (RAC1B) has been shown previously by RNA interference-mediated knockdown (KD) to function as a... 
RNA interference | pancreatic carcinoma | CRISPR/Cas9 | RAC1B | cell migration | TGF-β | ALK5
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2011, Volume 286, Issue 28, pp. 24638 - 24648
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/2014, Volume 289, Issue 49, pp. 34366 - 34377
Background: Inflammatory bowel disease management lacks therapies that heal the epithelial barrier. Results: PAR2 activation increases activities of MEK1/2 and... 
FACTOR VIIA | CROHNS-DISEASE | Mitogen-activated Protein Kinase (MAPK) | BIOCHEMISTRY & MOLECULAR BIOLOGY | ULCERATIVE-COLITIS | HUMAN-TISSUES | Intestinal Epithelium | BAD PHOSPHORYLATION | Protease | SIGNALING PATHWAY | EPIDERMAL-GROWTH-FACTOR | INFLAMMATORY BOWEL DISEASES | EXPRESSION | G Protein-coupled Receptor (GPCR) | Apoptosis | ARRESTIN-DEPENDENT ENDOCYTOSIS | Colon - cytology | Phosphatidylserines | RNA, Small Interfering - genetics | Epithelial Cells - metabolism | Apoptosis - drug effects | Epithelial Cells - drug effects | Humans | Receptor, PAR-2 - metabolism | Colon - drug effects | Apoptosis - genetics | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | MAP Kinase Kinase 1 - genetics | Receptor, PAR-2 - antagonists & inhibitors | Caspases - metabolism | Trypsin - pharmacology | Homeostasis - drug effects | Epithelial Cells - cytology | MAP Kinase Kinase 2 - genetics | Calcium Signaling | Receptor, PAR-2 - genetics | MAP Kinase Kinase 1 - antagonists & inhibitors | Caspases - genetics | Gene Expression Regulation | MAP Kinase Kinase 1 - metabolism | MAP Kinase Kinase 2 - metabolism | Colon - metabolism | Phosphatidylinositol 3-Kinases - genetics | Tumor Necrosis Factor-alpha - pharmacology | Poly(ADP-ribose) Polymerases - metabolism | Poly(ADP-ribose) Polymerases - genetics | MAP Kinase Kinase 2 - antagonists & inhibitors | Cell Line, Tumor | Oligopeptides - pharmacology | Interferon-gamma - pharmacology | RNA, Small Interfering - metabolism | Cell Biology
Journal Article