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1. Full Text Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
by Daniel F. Egan and David B. Shackelford and Maria M. Mihaylova and Sara Gelino and Rebecca A. Kohnz and William Mair and Debbie S. Vasquez and Aashish Joshi and Dana M. Gwinn and Rebecca Taylor and John M. Asara and James Fitzpatrick and Andrew Dillin and Benoit Viollet and Mondira Kundu and Malene Hansen and Reuben J. Shaw
Science (American Association for the Advancement of Science), ISSN 0036-8075, 1/2011, Volume 331, Issue 6016, pp. 456 - 461
Birds of prey | Medical research | Phosphorylation | Starvation | Mitochondria | Hepatocytes | Complementary DNA | Liver | REPORTS | Cell lines | Vehicles | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Classical genetics, quantitative genetics, hybrids | Biological and medical sciences | Animals | Genetics of eukaryotes. Biological and molecular evolution | AMP-Activated Protein Kinases - metabolism | Mitochondria, Liver - metabolism | Sequestosome-1 Protein | Humans | Caenorhabditis elegans Proteins - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Hepatocytes - metabolism | Autophagy | Autophagy-Related Protein-1 Homolog | Intracellular Signaling Peptides and Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Cell Line | Caenorhabditis elegans - metabolism | Signal Transduction | Cell Survival | Liver - metabolism | Metformin - pharmacology | Protein-Serine-Threonine Kinases - genetics | Phenformin - pharmacology | Transcription Factors - metabolism | Insulin - metabolism | Energy Metabolism | Intracellular Signaling Peptides and Proteins - chemistry | Mitochondria, Liver - ultrastructure | Cell Line, Tumor | Mice | Protein-Serine-Threonine Kinases - chemistry | Adaptor Proteins, Signal Transducing - metabolism | Caenorhabditis elegans Proteins - genetics | Autophagy (Cytology) | Research | Properties | Protein kinases | Index Medicus | Proteins | Yeast | Adenosines | Homeostasis | Nutrients | Kinases | Survival
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2. Full Text The AMPK signalling pathway coordinates cell growth, autophagy and metabolism
by Mihaylova, Maria M and Shaw, Reuben J
Nature cell biology, ISSN 1465-7392, 09/2011, Volume 13, Issue 9, pp. 1016 - 1023
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Eukaryota - cytology | AMP-Activated Protein Kinases - metabolism | Animals | Cell Proliferation | Models, Biological | Humans | Cell Polarity - physiology | Signal Transduction - physiology | Autophagy - physiology | Eukaryota - metabolism | Protein Subunits - metabolism | Physiological aspects | Cellular signal transduction | Research | Metabolism | Protein kinases | Index Medicus
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3. Full Text Phagocyte-specific S100 proteins and high-sensitivity C reactive protein as biomarkers for a risk-adapted treatment to maintain remission in juvenile idiopathic arthritis: a comparative study
by Gerss, Joachim and Roth, Johannes and Holzinger, Dirk and Ruperto, Nicolino and Wittkowski, Helmut and Frosch, Michael and Wulffraat, Nico and Wedderburn, Lucy and Stanevicha, Valda and Mihaylova, Dimitrina and Harjacek, Miroslav and Len, Claudio and Toppino, Claudia and Masi, Massimo and Minden, Kirsten and Saurenmann, Traudel and Uziel, Yosef and Vesely, Richard and Apaz, Maria Teresa and Kuester, Rolf-Michael and Elorduy, Maria Jesus Rua and Burgos-Vargas, Ruben and Ioseliani, Maka and Magni-Manzoni, Silvia and Unsal, Erbil and Anton, Jordi and Balogh, Zsolt and Hagelberg, Stefan and Mazur-Zielinska, Henryka and Tauber, Tsivia and Martini, Alberto and Foell, Dirk and Paediat Rheumatology Int Trials and Paediatric Rheumatology International Trials Organization (PRINTO) and for the Paediatric Rheumatology International Trials Organization (PRINTO)
Annals of the rheumatic diseases, ISSN 0003-4967, 12/2012, Volume 71, Issue 12, pp. 1991 - 1997
Life Sciences & Biomedicine | Rheumatology | Science & Technology | Biomarkers - metabolism | Recurrence | Calgranulin B - metabolism | Calgranulin A - metabolism | Humans | Leukocyte L1 Antigen Complex - metabolism | Risk Factors | Kaplan-Meier Estimate | Male | S100 Proteins - metabolism | Drug Monitoring - methods | Phagocytes - metabolism | Remission Induction | Arthritis, Juvenile - drug therapy | Arthritis, Juvenile - metabolism | S100A12 Protein | C-Reactive Protein - metabolism | Sensitivity and Specificity | ATP-Binding Cassette Transporters - metabolism | Female | Arthritis, Juvenile - epidemiology | Child | Antirheumatic Agents - therapeutic use | Control | Care and treatment | C-reactive protein | Juvenile arthritis | Physiological aspects | Inflammation | Research | Diagnosis | Biological markers | Health aspects | Immune system | Proteins | Immunology | Statistical analysis | Cytokines | Granulocytes | Laboratories | Bowel disease | Neutrophils | Biomarkers | Arthritis | Patients | Index Medicus | Medicin och hälsovetenskap
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4. Full Text Dietary and Metabolic Control of Stem Cell Function in Physiology and Cancer
by Mihaylova, Maria M and Sabatini, David M and Yilmaz, Ömer H
Cell stem cell, ISSN 1934-5909, 03/2014, Volume 14, Issue 3, pp. 292 - 305
Cell & Tissue Engineering | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Neoplasms - metabolism | Animals | Diet | Signal Transduction | Humans | Homeostasis | Neoplasms - physiopathology | Cell Transformation, Neoplastic - pathology | Stem Cells - metabolism | Index Medicus
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5. Full Text Class IIa Histone Deacetylases Are Hormone-Activated Regulators of FOXO and Mammalian Glucose Homeostasis
by Mihaylova, Maria M and Vasquez, Debbie S and Ravnskjaer, Kim and Denechaud, Pierre-Damien and Yu, Ruth T and Alvarez, Jacqueline G and Downes, Michael and Evans, Ronald M and Montminy, Marc and Shaw, Reuben J
Cell (Cambridge), ISSN 0092-8674, 2011, Volume 145, Issue 4, pp. 607 - 621
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Phosphorylation | Signal Transduction | Homeostasis | Histone Deacetylases - metabolism | Diabetes Mellitus, Type 2 - metabolism | Animals | Cell Nucleus - metabolism | Forkhead Transcription Factors - metabolism | Glucose - metabolism | Glucagon - metabolism | Forkhead Box Protein O1 | Mice | Acetylation | Protein-Serine-Threonine Kinases - metabolism | Gluconeogenesis | Type 2 diabetes | Hyperglycemia | Glucagon | Blood sugar | Glycogen | Analysis | Genetic research | DNA binding proteins | Gene expression | Phosphotransferases | Animal models | Index Medicus
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6. Full Text High-fat diet enhances stemness and tumorigenicity of intestinal progenitors
by Beyaz, Semir and Mana, Miyeko D and Roper, Jatin and Kedrin, Dmitriy and Saadatpour, Assieh and Hong, Sue-Jean and Bauer-Rowe, Khristian E and Xifaras, Michael E and Akkad, Adam and Arias, Erika and Pinello, Luca and Katz, Yarden and Shinagare, Shweta and Abu-Remaileh, Monther and Mihaylova, Maria M and Lamming, Dudley W and Dogum, Rizkullah and Guo, Guoji and Bell, George W and Selig, Martin and Nielsen, G. Petur and Gupta, Nitin and Ferrone, Cristina R and Deshpande, Vikram and Yuan, Guo-Cheng and Orkin, Stuart H and Sabatini, David M and Yilmaz, Ömer H
Nature (London), ISSN 0028-0836, 03/2016, Volume 531, Issue 7592, pp. 53 - 58
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Intestines - pathology | Obesity - chemically induced | Organoids - pathology | Cell Count | Humans | Diet, High-Fat - adverse effects | Male | Stem Cells - metabolism | beta Catenin - metabolism | Cell Self Renewal - drug effects | Genes, APC | Obesity - pathology | Animals | Signal Transduction - drug effects | Colonic Neoplasms - pathology | Organoids - metabolism | Organoids - drug effects | Stem Cells - drug effects | Stem Cells - pathology | Female | Mice | Stem Cell Niche - drug effects | Cell Transformation, Neoplastic - drug effects | PPAR delta - metabolism | Research | Health aspects | Carcinogenesis | Oncology, Experimental | Ketogenic diet | Cancer | Obesity | Diet | Stem cells | Ligands | Oils & fats | Colon | Small intestine | Tumors | Index Medicus
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7. Full Text Efficacy and safety of LDL-lowering therapy among men and women: meta-analysis of individual data from 174 000 participants in 27 randomised trials
by Fulcher, Jordan and O'Connell, Rachel and Voysey, Merryn and Emberson, Jonathan and Blackwell, Lisa and Mihaylova, Borislava and Collins, Rory and Kirby, Adrienne and Colhoun, Helen and La Rosa, John and Davis, Barry and Franzosi, Maria Grazia and Baigent, Colin and Keech, Anthony and De Lemos, J and Braunwald, E and Blazing, M and Murphy, S and Holdaas, H and Gordon, D and Davis, B and Koren, M and Poulter, N and Sever, P and Knopp, R.H and Holdaas, H and Jardine, A and Schmieder, R and Zannad, F and Goldbourt, U and Colhoun, H.M and Betteridge, D.J and Durrington, P.N and Fuller, J and Neil, A and Sacks, F and Pfeffer, M and Hawkins, C.M and Braunwald, E and Kjekshus, J and Wedel, H and Wikstrand, J and Barter, P and Tavazzi, L and Bloomfield, H and Robins, S and Collins, R and Parish, S and Peto, R and Sleight, P and Pedersen, T.R and Ridker, P.M and Holman, R and Meade, T and Simes, J and MacMahon, S and Marschner, I and Tonkin, A and Shaw, J and Serruys, P.W and Nakamura, H and Furberg, C and Byington, R and Ford, I and Blauw, G.J and Packard, C and Shepherd, J and Pedersen, T and Wilhelmsen, L and Braunwald, E and Cannon, C and Murphy, S and Collins, R and Armitage, J and Bowman, L and Parish, S and Sleight, P and Baigent, C and Collins, R and Rossouw, J and Probstfield, J and Shepherd, J and Cobbe, S and Macfarlane, P and Ford, I and Flather, M and Kastelein, J and Newman, C and Shear, C and Tobert, J and White, H and Keech, A.C and Marschner, I.C and Simes, J and Baigent, C and Blackwell, L and Collins, R and Emberson, J and Holland, L.E and Reith, C and Cholesterol Treatment Trialists' (CTT) Collaboration and Cholesterol Treatment Trialists' C
The Lancet (British edition), ISSN 0140-6736, 2015, Volume 385, Issue 9976, pp. 1397 - 1405
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage | Stroke - prevention & control | Cardiovascular Diseases - prevention & control | Humans | Proportional Hazards Models | Male | Treatment Outcome | Coronary Disease - prevention & control | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Sex Factors | Cholesterol, LDL - blood | Female | Percutaneous Coronary Intervention - statistics & numerical data | Databases, Factual | Low density lipoproteins | Analysis | Studies | Heart attacks | Drug therapy | Low density lipoprotein | Cholesterol | Statins | Index Medicus | Abridged Index Medicus
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