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Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 134, Issue 2, pp. 314 - 322.e9
Background Glucocorticoid functions are markedly impaired in patients with chronic obstructive pulmonary disease (COPD). The phosphodiesterase 4 inhibitor... 
Allergy and Immunology | dexamethasone | Roflumilast | corticosteroid resistance | neutrophil | chronic obstructive pulmonary disease | HISTONE DEACETYLASE ACTIVITY | BRONCHIAL EPITHELIAL-CELLS | MECHANISM | MIGRATION INHIBITORY FACTOR | AIRWAY INFLAMMATION | IMMUNOLOGY | SYSTEMIC INFLAMMATION | ALLERGY | GLUCOCORTICOID-RECEPTOR BETA | ENDOTHELIAL-CELLS | PDE4 INHIBITOR | EXPRESSION | Gene Expression - drug effects | Humans | Middle Aged | Macrophage Migration-Inhibitory Factors - metabolism | Male | Phosphatidylinositol 3-Kinases - metabolism | Pulmonary Disease, Chronic Obstructive - pathology | Matrix Metalloproteinase 9 - metabolism | Dexamethasone - pharmacology | Complex Mixtures - isolation & purification | Complex Mixtures - pharmacology | Female | Benzamides - pharmacology | Interleukin-8 - metabolism | Pulmonary Disease, Chronic Obstructive - metabolism | Intramolecular Oxidoreductases - metabolism | Neutrophils - metabolism | Cyclopropanes - pharmacology | Neutrophils - pathology | Biomarkers - metabolism | Neutrophils - drug effects | Adrenal Cortex Hormones - pharmacology | Histone Deacetylases - metabolism | Drug Resistance - drug effects | Phosphodiesterase 4 Inhibitors - pharmacology | Drug Synergism | Aminopyridines - pharmacology | Lipopolysaccharides - pharmacology | Tobacco - chemistry | Aged | Primary Cell Culture | Mitogen-Activated Protein Kinase Phosphatases - metabolism | Metabolites | Lung diseases, Obstructive | Corticosteroids | Chronic obstructive pulmonary disease | Kinases | Drug therapy | Gene expression | Mortality
Journal Article
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 135, Issue 2, pp. 470 - 476
Journal Article
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