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Neuron, ISSN 0896-6273, 04/2016, Volume 90, Issue 2, pp. 245 - 260
Journal Article
Nature Medicine, ISSN 1078-8956, 09/2014, Volume 20, Issue 10, pp. 1157 - 1164
Haploinsufficiency of the progranulin (PGRN) gene (GRN) causes familial frontotemporal lobar degeneration (FTLD) and modulates an innate immune response in... 
MEDICINE, RESEARCH & EXPERIMENTAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | NEURON LOSS | MICROGLIAL PHAGOCYTOSIS | NEUROINFLAMMATION | INFLAMMATION | MUTATIONS | ACCUMULATION | DYSFUNCTION | EXPRESSION | BRAIN | TRANSGENIC MICE | Microglia - metabolism | Up-Regulation | Humans | Male | Brain - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | Frontotemporal Lobar Degeneration - metabolism | Amyloid beta-Peptides - genetics | Immunity, Innate - physiology | Amyloid beta-Peptides - metabolism | Cognition - physiology | Frontotemporal Lobar Degeneration - therapy | Microglia - pathology | Female | Intercellular Signaling Peptides and Proteins - deficiency | Disease Models, Animal | Plaque, Amyloid - pathology | Mice, Inbred C57BL | Alzheimer Disease - therapy | Gene Expression Regulation | Intercellular Signaling Peptides and Proteins - genetics | Rats | Mice, Transgenic | Mice, Knockout | Animals | Alzheimer Disease - metabolism | Brain - pathology | Plaque, Amyloid - metabolism | Mice | Frontotemporal Lobar Degeneration - genetics | Alzheimer Disease - genetics | Phagocytosis | Index Medicus | Biological Sciences | Basic Medicine | Neurosciences | Naturvetenskap | Medical and Health Sciences | Medicin och hälsovetenskap | Biologiska vetenskaper | Medicinska och farmaceutiska grundvetenskaper | Natural Sciences | Neurovetenskaper
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 01/2013, Volume 124, Issue 1, pp. 59 - 68
Several epidemiological and preclinical studies suggest that non‐steroidal anti‐inflammatory drugs ( NSAID s), which inhibit cyclooxygenase ( COX ), reduce the... 
3 × Tg | SC | A | lzheimer's disease | 1 | AD | mice | COX | microglia | 560 | 3 × Tg-AD mice | COX-1 | SC-560 | Alzheimer's disease | BIOCHEMISTRY & MOLECULAR BIOLOGY | MONOCLONAL-ANTIBODY | 3 Tg-AD mice | KAPPA-B | TAU PATHOLOGY | SYNAPTIC PLASTICITY | NEUROSCIENCES | A-BETA | CONTROL BRAIN | INFLAMMATORY RESPONSE | EXPRESSION | TRANSGENIC MICE | Pyrazoles - therapeutic use | Alzheimer Disease - complications | Humans | Glycogen Synthase Kinase 3 beta | Male | Glial Fibrillary Acidic Protein - metabolism | Alzheimer Disease - pathology | tau Proteins - genetics | Phosphorylation - drug effects | Disease Models, Animal | Microglia - drug effects | Gene Expression Regulation - genetics | Phagocytes - drug effects | Mice, Inbred C57BL | Presenilin-1 - genetics | Mice, Transgenic | Glycogen Synthase Kinase 3 - metabolism | Maze Learning - drug effects | Mutation - genetics | Gene Expression Regulation - drug effects | Amyloidogenic Proteins - metabolism | Amyloid beta-Protein Precursor - genetics | Animals | Memory Disorders - drug therapy | Memory Disorders - etiology | Mice | Alzheimer Disease - genetics | Cyclooxygenase Inhibitors - therapeutic use | COX-2 inhibitors | Genetic engineering | Fluocinolone acetonide | Amyloid beta-protein | Inhibitor drugs | Alzheimers disease | Memory | Neurobiology | Index Medicus
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2018, Volume 14, Issue 7, pp. P1083 - P1083
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2018, Volume 14, Issue 7, pp. P1080 - P1080
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 05/2017, Volume 114, Issue 19, pp. 5029 - 5034
Frontotemporal dementia (FTD) is the second most common dementia before 65 years of age. Haploinsufficiency in the progranulin (GRN) gene accounts for 10% of... 
OCD | Progranulin | TNF | FTD | Microglia | CELLS | STIMULATION | LOBAR DEGENERATION | MULTIDISCIPLINARY SCIENCES | TAU | SOCIAL-BEHAVIOR | MUTANT MICE | NEUROINFLAMMATION | IN-VIVO | DISEASE | progranulin | microglia | BRAIN | Index Medicus | Biological Sciences
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2017, Volume 13, Issue 7, pp. P1242 - P1243
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2018, Volume 14, Issue 7, pp. P691 - P691
Journal Article
Brain Research, ISSN 0006-8993, 2008, Volume 1216, pp. 92 - 103
Journal Article
Journal of Neuroinflammation, ISSN 1742-2094, 01/2012, Volume 9, Issue 1, pp. 22 - 22
Journal Article