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Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 5345 - 9
The assay for transposase-accessible chromatin using sequencing (ATAC-seq) is widely used to identify regulatory regions throughout the genome. However, very... 
MEMORY | T-BET | MULTIDISCIPLINARY SCIENCES | TRANSPOSITION | TRANSCRIPTION | Transcription factors | Chromatin | Profiling | Accessibility | Cryopreservation | Splenocytes | Tagging | Genomes | Regulatory sequences | Transposase | Gene sequencing | Immune system
Journal Article
ISSN 1548-7091, 2017
Single-cell RNA sequencing (scRNA-seq) has become an established and powerful method to investigate transcriptomic cell-to-cell variation, thereby revealing... 
Animals | Sequence Analysis, RNA | Sensitivity and Specificity | Workflow | Mice | Embryonic Stem Cells | Single-Cell Analysis | RNA, Messenger | Freezing | Poly A
Journal Article
Methods in molecular biology (Clifton, N.J.), 2019, Volume 1979, p. 9
The starting material for all single-cell protocols is a cell suspension. The particular functions and spatial distribution of immune cells generally make them... 
Journal Article
Journal Article
Nature, ISSN 0028-0836, 11/2018, Volume 563, Issue 7730, pp. 197 - 202
Journal Article
Current Opinion in Systems Biology, ISSN 2452-3100, 10/2017, Volume 5, pp. 63 - 71
Our body is composed of a diverse set of cells that together perform numerous functions in a highly coordinated manner, allowing a timely response to external... 
Pseudotime | Cell differentiation | Immunity | Cell heterogeneity | Single-cell
Journal Article
Cell, ISSN 0092-8674, 02/2019, Volume 176, Issue 4, pp. 882 - 896.e18
T helper type 2 (Th2) cells are important regulators of mammalian adaptive immunity and have relevance for infection, autoimmunity, and tumor immunology. Using... 
pooled screen | knockout | CD4 T helper cell | mouse | CRISPR | retrovirus | overexpression | ChIP-seq | Cas9 | ATAC-seq | CD4 T helper cell | BET | REGULATOR | ENHANCER LANDSCAPE | CHROMATIN | RNA-SEQ | SEQUENCE ALIGNMENT | QUANTIFICATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | IL-4 | TRANSCRIPTION FACTOR GATA-3 | CYTOKINE GENE-EXPRESSION | CELL BIOLOGY
Journal Article
Frontiers in cardiovascular medicine, ISSN 2297-055X, 2018, Volume 5, p. 167
The recent development of single cell gene expression technologies, and especially single cell transcriptomics, have revolutionized the way biologists and... 
Heart | Usage | Research | Nucleotide sequencing | Gene expression | Health aspects | DNA sequencing | transcriptomics | single cell | cellular landscape | heart | gene expression | qRT-PCR
Journal Article
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