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by Armangue, Thaís and Spatola, Marianna and Vlagea, Alexandru and Mattozzi, Simone and Cárceles-Cordon, Marc and Martinez-Heras, Eloy and Llufriu, Sara and Muchart, Jordi and Erro, María Elena and Abraira, Laura and Moris, German and Monros-Giménez, Luis and Corral-Corral, Íñigo and Montejo, Carmen and Toledo, Manuel and Bataller, Luis and Secondi, Gabriela and Ariño, Helena and Martínez-Hernández, Eugenia and Juan, Manel and Marcos, Maria Angeles and Alsina, Laia and Saiz, Albert and Rosenfeld, Myrna R and Graus, Francesc and Dalmau, Josep and Aguilera-Albesa, Sergio and Amado-Puentes, Alfonso and Arjona-Padillo, Antonio and Arrabal, Luisa and Arratibel, Izascun and Aznar-Laín, Gemma and Bellas-Lamas, Paula and Bermejo, Teresa and Boyero-Durán, Sabas and Camacho, Ana and Campo, Andrea and Campos, Dulce and Cantarín-Extremera, Verónica and Carnero, Cristóbal and Conejo-Moreno, David and Dapena, Marta and Dacruz-Álvarez, David and Delgadillo-Chilavert, Verónica and Deyà, Angela and Estela-Herrero, Jordi and Felipe, Anna and Fernández-Cooke, Elisa and Fernández-Ramos, Joaquín and Fortuny, Claudia and García-Monco, Juan C and Gili, Teresa and González-Álvarez, Verónica and Guerri, Robert and Guillén, Sara and Hedrera-Fernández, Antonio and López, María and López-Laso, Eduardo and Lorenzo-Ruiz, María and Madruga, Marcos and Málaga-Diéguez, Ignacio and Martí-Carrera, Itxaso and Martínez-Lacasa, Xavier and Martín-Viota, Lucía and Martín Gil, Leticia and Martínez-González, María-Jesús and Moreira, Antia and Miranda-Herrero, María C and Monge, Lorena and Muñoz-Cabello, Beatriz and Navarro-Morón, Juan and Neth, Olaf and Noguera-Julian, Antoni and Nuñez-Enamorado, Noemí and Pomar, Virginia and Portillo-Cuenca, Juan C and Poyato, María and Prieto, Luis and Querol, Luis and Rodríguez-Rodríguez, Eloy and Sarria-Estrada, Silvana and Sierra, Concepción and Soler-Palacín, Pere and Soto-Insuga, Víctor and Toledo-Bravo, Laura and Tomás, Miguel and Torres-Torres, Carmen and Turón, Eulàlia and Zabalza, Ana and Spanish Herpes Simplex Encephalitis Study Group and Spanish Herpes Simplex
The Lancet Neurology, ISSN 1474-4422, 09/2018, Volume 17, Issue 9, pp. 760 - 772
Herpes simplex encephalitis can trigger autoimmune encephalitis that leads to neurological worsening. We aimed to assess the frequency, symptoms, risk factors,... 
ANTIBODIES | STROKE | RELAPSE | VIRUS ENCEPHALITIS | SERIES | ADULTS | D-ASPARTATE RECEPTOR | CLINICAL NEUROLOGY | CHILDREN | Autoantibodies - metabolism | Encephalitis, Herpes Simplex - diagnostic imaging | Encephalitis - diagnostic imaging | Humans | Middle Aged | Child, Preschool | Male | Encephalitis, Herpes Simplex - epidemiology | Encephalitis, Herpes Simplex - complications | Young Adult | Hashimoto Disease - epidemiology | Statistics, Nonparametric | Adult | Female | Child | Receptors, N-Methyl-D-Aspartate - immunology | Hashimoto Disease - etiology | Encephalitis - epidemiology | Encephalitis, Herpes Simplex - cerebrospinal fluid | Risk Factors | Rats | Hippocampus - pathology | Hashimoto Disease - diagnostic imaging | Hippocampus - metabolism | Magnetic Resonance Imaging | Animals | Adolescent | Encephalitis - cerebrospinal fluid | Glutamate Decarboxylase - metabolism | Aged | Hashimoto Disease - cerebrospinal fluid | Cohort Studies | Encephalitis - etiology | Demography | Glutamic acid receptors (ionotropic) | Epilepsy | Herpes simplex | Antibodies | Glutamic acid receptors | Risk factors | Apathy | Psychosis | Immunotherapy | Dysphagia | Amnesia | Children | Age | Seizures | Encephalitis | Antigens | Immunoglobulins | Consciousness | N-Methyl-D-aspartic acid receptors | Regression analysis | Patients | Choreoathetosis | Infectious diseases | Insomnia | Herpes viruses | Autoimmune diseases | Viral infections | Autoimmunity | Herpes | Autoimmunitat | Herpesvirus diseases | Encefalitis
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 11/2018, Volume 83, Issue 21, pp. 13019 - 13029
Latent electrophiles are nowadays very attractive chemical entities for drug discovery, as they are unreactive unless activated upon binding with the specific... 
TRIFLUOROMETHYL-SUBSTITUTED PHENOLS | MOLECULAR-DYNAMICS | PHOTOCHEMICAL REACTIVITY | COVALENT INHIBITORS | STRUCTURAL BASIS | HUMAN SERUM-ALBUMIN | DRUG DISCOVERY | CHEMISTRY, ORGANIC | FORCE-FIELD | PROTEINS | SELECTIVITY
Journal Article
Journal Article
Annals of Neurology, ISSN 0364-5134, 05/2019, Volume 85, Issue 5, pp. 740 - 751
Journal Article
Journal of Inherited Metabolic Disease, ISSN 0141-8955, 9/2017, Volume 40, Issue 5, pp. 753 - 754
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1007/s10545-017-0056-0 (6)... 
Human Genetics | Biochemistry, general | Pediatrics | Internal Medicine | Medicine & Public Health | Metabolic Diseases | Medicine, Experimental | Medical research | Medical colleges | Children | Analysis | Diseases | Atrophy | Cerebellum | Phosphomannomutase
Journal Article
Chemical science, ISSN 2041-6520, 04/2017, Volume 8, Issue 4, pp. 2621 - 2628
A multidisciplinary strategy to obtain structural information on the intraprotein region is described here. As probe ligands, ( )- and ( )- (the methyl esters... 
Journal Article
FRONTIERS IN PHARMACOLOGY, ISSN 1663-9812, 09/2019, Volume 10
Triflusal is a platelet antiaggregant employed for the treatment and prevention of thromboembolic diseases. After administration, it is biotransformed into its... 
DRUG | docking and molecular dynamics | PHOTOALLERGY | PHOTOSENSITIVITY | triflusal metabolite | ESTERASE-ACTIVITY | proteomic analysis | AMBER | fluorescence | 2-HYDROXY-4-TRIFLUOROMETHYLBENZOIC ACID | FORCE-FIELD | PHARMACOLOGY & PHARMACY | MOLECULAR-DYNAMICS SIMULATIONS | human serum albumin | BINDING | METABOLITE | Albumin | Molecular dynamics | Fluorescence | Analysis | Investigations
Journal Article
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, ISSN 1386-1425, 02/2020, Volume 226, p. 117652
Transient absorption spectroscopy in combination with in silico methods has been employed to study the interactions between human serum albumin (HSA) and the... 
Human serum albumin | Docking | Molecular dynamics simulations | Carprofen | Laser flash photolysis | DRUG-BINDING | SERUM-ALBUMIN | PHOTOIONIZATION | CHLORPROMAZINE | SPECTROSCOPY | PROMAZINE | TRIPLET EXCITED-STATES | PHENOTHIAZINE | PHOTOOXIDATION
Journal Article
AJIC: American Journal of Infection Control, ISSN 0196-6553, 2012, Volume 40, Issue 5, pp. 396 - 407
The results of a surveillance study conducted by the International Nosocomial Infection Control Consortium (INICC) from January 2004 through December 2009 in... 
Infectious Disease | Infection Control | Nosocomial infection | Ventilator-associated pneumonia | Low-income countries | Bloodstream infection | Developing countries | Central line-associated bloodstream infection | Limited-resources countries | Health care-associated infection | Urinary tract infection | Catheter-associated urinary tract infection | Network | Antibiotic resistance | Hospital infection | Device-associated infection | MORTALITY | INTENSIVE-CARE UNITS | CONTROL PROGRAM | RATES | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | PERFORMANCE FEEDBACK | SAFETY NETWORK | INFECTIOUS DISEASES | LENGTH-OF-STAY | ARGENTINEAN HOSPITALS | BLOOD-STREAM INFECTIONS | Africa - epidemiology | Prevalence | Prospective Studies | Humans | Middle Aged | Cross Infection - mortality | Child, Preschool | Infant | Male | Young Adult | Aged, 80 and over | Bacteria - classification | Adult | Female | Child | Infant, Newborn | Cross Infection - epidemiology | Latin America - epidemiology | Intensive Care Units | Europe - epidemiology | International Cooperation | Asia - epidemiology | Bacteria - isolation & purification | Adolescent | Bacterial Infections - epidemiology | Aged | Bacterial Infections - mortality | Consortia | Medical colleges | Pneumonia | Hotels and motels | Bacterial pneumonia | Staphylococcus aureus infections | Urinary tract infections | Health aspects | Antibacterial agents | Public health | Infection control
Journal Article