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by Gusarova, Viktoria and O'Dushlaine, Colm and Teslovich, Tanya M and Benotti, Peter N and Mirshahi, Tooraj and Gottesman, Omri and Van Hout, Cristopher V and Murray, Michael F and Mahajan, Anubha and Nielsen, Jonas B and Fritsche, Lars and Wulff, Anders Berg and Gudbjartsson, Daniel F and Sjögren, Marketa and Emdin, Connor A and Scott, Robert A and Lee, Wen-Jane and Small, Aeron and Kwee, Lydia C and Dwivedi, Om Prakash and Prasad, Rashmi B and Bruse, Shannon and Lopez, Alexander E and Penn, John and Marcketta, Anthony and Leader, Joseph B and Still, Christopher D and Kirchner, H. Lester and Mirshahi, Uyenlinh L and Wardeh, Amr H and Hartle, Cassandra M and Habegger, Lukas and Fetterolf, Samantha N and Tusie-Luna, Teresa and Morris, Andrew P and Holm, Hilma and Steinthorsdottir, Valgerdur and Sulem, Patrick and Thorsteinsdottir, Unnur and Rotter, Jerome I and Chuang, Lee-Ming and Damrauer, Scott and Birtwell, David and Brummett, Chad M and Khera, Amit V and Natarajan, Pradeep and Orho-Melander, Marju and Flannick, Jason and Lotta, Luca A and Willer, Cristen J and Holmen, Oddgeir L and Ritchie, Marylyn D and Ledbetter, David H and Murphy, Andrew J and Borecki, Ingrid B and Reid, Jeffrey G and Overton, John D and Hansson, Ola and Groop, Leif and Shah, Svati H and Kraus, William E and Rader, Daniel J and Chen, Yii-Der I and Hveem, Kristian and Wareham, Nicholas J and Kathiresan, Sekar and Melander, Olle and Stefansson, Kari and Nordestgaard, Børge G and Tybjærg-Hansen, Anne and Abecasis, Goncalo R and Altshuler, David and Florez, Jose C and Boehnke, Michael and McCarthy, Mark I and Yancopoulos, George D and Carey, David J and Shuldiner, Alan R and Baras, Aris and Dewey, Frederick E and Gromada, Jesper and Diabetes - Cardiovascular Disease and Kardiovaskulär forskning - hypertoni and Cardiovascular Research - Hypertension and Diabetes - kardiovaskulär sjukdom and Lund University and Genomics, Diabetes and Endocrinology and EpiHealth: Epidemiology for Health and Genomik, diabetes och endokrinologi and Institutionen för kliniska vetenskaper, Malmö and Lunds universitet and Department of Clinical Sciences, Malmö
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2252 - 11
Angiopoietin-like 4 (ANGPTL4) is an endogenous inhibitor of lipoprotein lipase that modulates lipid levels, coronary atherosclerosis risk, and nutrient... 
HEART-DISEASE | REMNANT CHOLESTEROL | PLASMA-LIPIDS | MULTIDISCIPLINARY SCIENCES | MICE | ANGIOPOIETIN-LIKE PROTEIN-4 | LIPOPROTEIN-LIPASE | HAN CHINESE | CHINESE POPULATION | GENOME-WIDE ASSOCIATION | ADIPOSE-TISSUE | Diabetes Mellitus, Type 2 - genetics | Humans | Homeostasis | Male | Diabetes Mellitus, Type 2 - metabolism | Case-Control Studies | Genetic Variation | Diabetes Mellitus, Type 2 - etiology | Female | Lipoprotein Lipase - metabolism | Genetic Association Studies | Mice, Inbred C57BL | Risk Factors | Gene Silencing | Angiopoietin-like 4 Protein - deficiency | Mice, Knockout | Whole Exome Sequencing | Animals | Insulin Resistance - genetics | Angiopoietin-like 4 Protein - metabolism | Heterozygote | Mice | Blood Glucose - metabolism | Amino Acid Substitution | Angiopoietin-like 4 Protein - genetics | Deactivation | Angiopoietin | Diabetes mellitus | Health risks | Risk reduction | Risk | Lipoprotein lipase | Glucose | Lipase | Inactivation | Insulin | Proteins | Confidence intervals | Sensitivity | Nutrient loss | Rodents | Arteriosclerosis | Atherosclerosis | Genetics | Diabetes | Diabetes mellitus (non-insulin dependent) | Medicinsk genetik | Basic Medicine | Medical Genetics | Clinical Medicine | Medical and Health Sciences | Endokrinologi och diabetes | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Klinisk medicin | Endocrinology and Diabetes
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 03/2018, Volume 378, Issue 12, pp. 1096 - 1106
Journal Article
Genetics in Medicine, ISSN 1098-3600, 06/2019, Volume 21, Issue 6, pp. 1417 - 1424
Precision health initiatives and reduced sequencing costs are driving large-scale human genome analyses. Genetic variant curation is a bottleneck in clinical... 
exome sequencing | secondary findings | sequence scaling | variant curation | genomic screening
Journal Article
Biophysical Journal, ISSN 0006-3495, 02/2018, Volume 114, Issue 3, pp. 123a - 123a
Journal Article
Diabetes, ISSN 0012-1797, 06/2019, Volume 68, Issue Supplement 1, p. 238
Journal Article
Biophysical Journal, ISSN 0006-3495, 01/2013, Volume 104, Issue 2, pp. 274a - 274a
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 02/2015, Volume 372, Issue 9, pp. 881 - 883
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2014, Volume 9, Issue 4, p. e93629
Journal Article
The New England journal of medicine, ISSN 0028-4793, 02/2015, Volume 372, Issue 9, pp. 881 - 882
Journal Article
Journal Article
BMC Genomics, ISSN 1471-2164, 06/2016, Volume 17, Issue Suppl 2
Alzheimer's disease (AD) represents the most common form of dementia in elder populations with approximately 30 million cases worldwide. Genome wide genotyping... 
Analysis | Genetic aspects | Diagnosis | Research | Homozygosity | Alzheimer's disease | Risk factors | Dementia
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2012, Volume 287, Issue 10, pp. 7121 - 7133
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/2010, Volume 285, Issue 53, pp. 41290 - 41299
G protein-activated inwardly rectifying potassium (GIRK or Kir3) channels are directly gated by the βγ subunits of G proteins and contribute to inhibitory... 
Potassium Channels | G Protein-coupled Receptors (GPCR) | Neurotransmitters | Signal Transduction | Anesthetic | G Proteins | Neurobiology | Gating
Journal Article