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1. Full Text Zoonotic transmission of hepatitis E virus from deer to human beings
by Tei, Shuchin and Kitajima, Naoto and Takahashi, Kazuaki and Mishiro, Shunji
The Lancet, ISSN 0140-6736, 08/2003, Volume 362, Issue 9381, pp. 371 - 373
Zoonosis has been suggested for hepatitis E virus (HEV) infection, but so far is based only on indirect evidence. We experienced a series of cases of HEV... 
MEDICINE, GENERAL & INTERNAL | Animals | Hepatitis E virus - immunology | Humans | RNA, Viral - analysis | Deer - virology | Hepatitis E - veterinary | RNA, Viral - immunology | Hepatitis E virus - genetics | Hepatitis E - transmission | Meat - virology | Zoonoses - transmission | Communicable diseases | Development and progression | Research | Deer | Risk factors | Hepatitis E virus | Diseases | Zoonoses | Hepatitis | Infections | Meat | Hypotheses | Immunoglobulins | Nucleotide sequence | Industrialized nations | Viruses | Ribonucleic acid--RNA | Patients
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2. Full Text Celiac disease in non-clinical populations of Japan
by Fukunaga, Mai and Ishimura, Norihisa and Fukuyama, Chika and Izumi, Daisuke and Ishikawa, Nahoko and Araki, Asuka and Oka, Akihiko and Mishiro, Tomoko and Ishihara, Shunji and Maruyama, Riruke and Adachi, Kyoichi and Kinoshita, Yoshikazu
Journal of Gastroenterology, ISSN 0944-1174, 2/2018, Volume 53, Issue 2, pp. 208 - 214
Celiac disease is a chronic autoimmune enteropathy caused by gluten ingestion. While its prevalence in Western countries is reported to be as high as 1%, the... 
Anti-tissue transglutaminase IgA | Celiac disease | Medicine & Public Health | Colorectal Surgery | Antibody | Hepatology | Gastroenterology | Abdominal Surgery | HLA | Surgical Oncology | DIAGNOSIS | MANAGEMENT | SUSCEPTIBILITY | GUIDELINES | SMALL-INTESTINE | PREVALENCE | HLA-DQ | GLUTEN SENSITIVITY | GASTROENTEROLOGY & HEPATOLOGY | IRRITABLE-BOWEL-SYNDROME | BRITISH SOCIETY | Japan - epidemiology | Abdominal Pain - etiology | Age Distribution | Prevalence | Comorbidity | Autoantibodies - blood | Humans | Middle Aged | Diarrhea - epidemiology | Male | Transglutaminases - immunology | Abdominal Pain - epidemiology | Celiac Disease - pathology | Duodenoscopy | Celiac Disease - immunology | Duodenum - pathology | Celiac Disease - complications | Immunoglobulin A - blood | Adult | Diarrhea - etiology | Female | Aged | Celiac Disease - epidemiology | Intestinal Mucosa - pathology | Medicine, Experimental | Medical research | Medical screening | Immunoglobulin A | Typing | Biopsy | Mucosa | Population studies | Histocompatibility antigen HLA | Tissue typing | Gluten | Small intestine | Transglutaminase 2
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3. Full Text Severe Hepatitis E Virus Infection after Ingestion of Uncooked Liver from a Wild Boar
by Hiroyuki Matsuda and Katsuo Okada and Kazuaki Takahashi and Shunji Mishiro
The Journal of Infectious Diseases, ISSN 0022-1899, 9/2003, Volume 188, Issue 6, pp. 944 - 944
Hepatitis | RNA | Swine | Liver | Written correspondence | Correspondence | Infections | Hepatitis E virus | Zoonoses | INFECTIOUS DISEASES | Liver - virology | Food Contamination | Humans | Japan | Middle Aged | Hepatitis E - virology | Male | Zoonoses - transmission | Animals | Hepatitis E - veterinary | Aged | Hepatitis E - transmission | Sus scrofa
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4. Full Text Complete or near-complete nucleotide sequences of hepatitis E virus genome recovered from a wild boar, a deer, and four patients who ate the deer
by Takahashi, Kazuaki and Kitajima, Naoto and Abe, Natsumi and Mishiro, Shunji
Virology, ISSN 0042-6822, 2004, Volume 330, Issue 2, pp. 501 - 505
Zoonosis has been implicated in hepatitis E virus (HEV) transmission. We examined wild boar living in a forest of Hyogo prefecture, Japan, and found HEV RNA in... 
Single-stranded RNA virus | Interspecies transmission | Zoonosis | Hepatitis E virus (HEV) | CROSS-SPECIES INFECTION | single-stranded RNA virus | hepatitis E virus (HEV) | VIROLOGY | interspecies transmission | JAPAN | HEV | zoonosis | Genome, Viral | Swine Diseases - virology | Humans | Japan | Molecular Sequence Data | Hepatitis E - virology | Hepatitis E virus - genetics | Phylogeny | Sus scrofa - virology | DNA, Complementary - isolation & purification | Sequence Analysis, DNA | Zoonoses - virology | Sequence Homology | Animals | Base Sequence | Deer - virology | Hepatitis E - veterinary | RNA, Viral - metabolism | DNA, Complementary - chemistry | Hepatitis E - transmission | RNA, Viral - isolation & purification | Hepatitis E virus - isolation & purification
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5. Full Text High prevalence of hepatitis B infections in Burkina Faso (1996-2017): A systematic review with meta-analysis of epidemiological studies
by Lingani, Moussa and Akita, Tomoyuki and Ouoba, Serge and Sanou, Armel Moumini and Sugiyama, Aya and Tarnagda, Zekiba and Ohisa, Masayuki and Tinto, Halidou and Mishiro, Shunji and Tanaka, Junko
BMC Public Health, ISSN 1471-2458, 04/2018, Volume 18, Issue 1, pp. 551 - 11
Background: Hepatitis B virus (HBV) infection was long considered an important public health concern in Burkina Faso and still represents a major cause of... 
Burkina Faso | Epidemiology | Viral infection | Hepatitis B | Meta-analysis | GLOBAL BURDEN | SUB-SAHARAN AFRICA | PREVENTION | BLOOD-DONORS | HUMAN-IMMUNODEFICIENCY-VIRUS | C VIRUSES | SEROPREVALENCE | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | CAMILLE MEDICAL-CENTER | HIV | PREGNANT-WOMEN | Infection | Medical research | Liver cancer | National health insurance | Pregnant women | Analysis | Liver | Medicine, Experimental | Health aspects | Liver cirrhosis | Health care | Immunization | Hepatitis B surface antigen | Rural areas | Urban areas | Vaccination | Viruses | Systematic review | Cortex (visual) | Infections | Blood donors | Scientific papers | Pregnancy | Hepatitis | Cirrhosis | Womens health | Human immunodeficiency virus--HIV | Hepatitis B virus | Public health | Cancer
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6. Full Text Oral microbiome alterations of healthy volunteers with proton pump inhibitor
by Mishiro, Tsuyoshi and Oka, Kentaro and Kuroki, Yasutoshi and Takahashi, Motomichi and Tatsumi, Kasumi and Saitoh, Tsukasa and Tobita, Hiroshi and Ishimura, Norihisa and Sato, Shuichi and Ishihara, Shunji and Sekine, Joji and Wada, Koichiro and Kinoshita, Yoshikazu
Journal of Gastroenterology and Hepatology, ISSN 0815-9319, 05/2018, Volume 33, Issue 5, pp. 1059 - 1066
Background and Aim Acid suppressive agents including proton pump inhibitors (PPIs) are used as first‐line treatment for various acid‐related gastrointestinal... 
microbiome | proton pump inhibitor | 16S rRNA sequence | ALTER | COMMUNITY-ACQUIRED PNEUMONIA | ROBUSTNESS | ADULTS | RISK | GUT MICROBIOTA | TRIAL | THERAPY | GASTROESOPHAGEAL-REFLUX DISEASE | GASTROENTEROLOGY & HEPATOLOGY | LIFE | Microbiota (Symbiotic organisms) | RNA | Gastrointestinal diseases | Gastrointestinal system | Biological diversity | Periodontics | rRNA 16S | Gastrointestinal tract diseases | Digestive system | Secretion | Microbiomes | Gastrointestinal tract | Acid production | Omeprazole | Microbiota | Microorganisms | Acids | Bacteria | Feces | Digestive tract | Saliva | Species richness | Gastric juice
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7. Full Text Butyric acid attenuates intestinal inflammation in murine DSS-induced colitis model via milk fat globule-EGF factor 8
by Mishiro, Tsuyoshi and Kusunoki, Ryusaku and Otani, Aya and Ansary, Md Mesbah Uddin and Tongu, Miki and Harashima, Nanae and Yamada, Takaya and Sato, Shuichi and Amano, Yuji and Itoh, Kazuhito and Ishihara, Shunji and Kinoshita, Yoshikazu
Laboratory Investigation, ISSN 0023-6837, 07/2013, Volume 93, Issue 7, pp. 834 - 843
Butyric acid, a short-chain fatty acid and one of the main metabolites of intestinal microbial fermentation of dietary fiber, has been shown to have an... 
apoptosis | butyric acid | 16S rRNA sequence | intestinal inflammation | milk fat globule-epidermal growth factor 8 | MEDICINE, RESEARCH & EXPERIMENTAL | CONTROLLED-TRIAL | GROWTH-FACTOR 8 | FACTOR-VIII | ENEMAS | MICROBIOTA | PATHOLOGY | BOWEL-DISEASE | ROLES | APOPTOTIC CELLS | HEALTH | DISTAL ULCERATIVE-COLITIS | Milk Proteins - metabolism | Cell Line | Dextran Sulfate | Promoter Regions, Genetic | Up-Regulation | Metagenome - drug effects | Mice, Inbred C57BL | Administration, Rectal | Male | Histamine Antagonists - therapeutic use | Mice, Knockout | Butyric Acid - therapeutic use | Animals | Colitis - microbiology | Colitis - chemically induced | Colitis - metabolism | Antigens, Surface - metabolism | Histamine Antagonists - pharmacology | Butyric Acid - pharmacology | Colitis - drug therapy | Mice | Histones - metabolism | Disease Models, Animal
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8. Full Text Hepatitis e epidemic, Biratnagar, Nepal, 2014
by Shrestha, Ananta and Lama, Thupten K and Karki, Sneha and Sigdel, Deepak R and Rai, Utsav and Rauniyar, Shyam K and Al-Mahtab, Mamun and Takahashi, Kazuaki and Arai, Masahiro and Akbar, Sheikh M.F and Mishiro, Shunji
Emerging Infectious Diseases, ISSN 1080-6040, 2015, Volume 21, Issue 4, pp. 711 - 713
INFECTIOUS DISEASES | IMMUNOLOGY | Hepatitis E - epidemiology | Hepatitis E virus - classification | Hepatitis E virus - immunology | Hepatitis Antibodies - immunology | Humans | RNA, Viral | Hepatitis E - immunology | Hepatitis E virus - genetics | Phylogeny | Nepal - epidemiology | Population Surveillance | viruses | open reading frame 2 | epidemic | water | Letter | Hepatitis E Epidemic, Biratnagar, Nepal, 2014 | hepatitis E virus | phylogenetic analysis | acute icteric hepatitis E | Biratnagar | HEV | Letters to the Editor | Nepal
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9. Full Text Detection of the GBV-C hepatitis virus genome in serum from patients with fulminant hepatitis of unknown aetiology
by Yoshiba, M and Okamoto, H and Mishiro, S
The Lancet, ISSN 0140-6736, 1995, Volume 346, Issue 8983, pp. 1131 - 1132
Hepatitis viruses A, B, C, D, and E have not accounted for all cases of hepatitis, hence ''non A-E'' agent(s) might be implicated. A set of new viruses (GBV-A,... 
MEDICINE, GENERAL & INTERNAL | Genome, Viral | Humans | Middle Aged | Flavivirus - genetics | Molecular Sequence Data | Male | RNA, Viral - genetics | Base Sequence | Hepatitis, Viral, Human - virology | Adolescent | Polymerase Chain Reaction | Adult | Female | Flavivirus Infections - virology | Aged | Polymerase chain reaction | Hepatitis, Viral | Genomes | Genetic aspects | Hepatitis | Hepatology
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10. Full Text Persistent infection of hepatitis E virus transmitted by blood transfusion in a patient with T‐cell lymphoma
by Tamura, Akinori and Shimizu, Yohko K and Tanaka, Torahiko and Kuroda, Kazumichi and Arakawa, Yasuyuki and Takahashi, Kazuaki and Mishiro, Shunji and Shimizu, Kazufumi and Moriyama, Mitsuhiko
Hepatology Research, ISSN 1386-6346, 02/2007, Volume 37, Issue 2, pp. 113 - 120
Aim:  With advent of reverse‐transcription (RT)/polymerase chain reaction (PCR) for detection of the hepatitis E viral genome, we carried out retrospective... 
persistent infection | hepatitis E virus | transfusion‐transmitted hepatitis E | Transfusion-transmitted hepatitis E | Persistent infection | Hepatitis E virus | transfusion-transmitted hepatitis E | GASTROENTEROLOGY & HEPATOLOGY | SWINE | JAPAN
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11. Full Text Retained Rice Cake: A Unique Upper Gastrointestinal Foreign Body: Case Report and a Literature Review
by Oka, A and Ishihara, S and Mikami, H and Sonoyama, H and Mishiro, T and Tobita, H and Kawashima, K and Miyake, T and Ishimura, N and Furuta, K and Kinoshita, Y and Nishina, M
INTERNAL MEDICINE, ISSN 0918-2918, 2019, Volume 58, Issue 17, pp. 2485 - 2494
As a rarely recognized foreign body in the upper gastrointestinal tract, rice cake frequently requires endoscopic removal. We herein report six patients with... 
mucosal injury | MEDICINE, GENERAL & INTERNAL | obstruction | MANAGEMENT | upper gastrointestinal tract | rice cake | foreign body | BODIES | thermal injury | Medical personnel | Spectroscopy | Physicians | Mucosa | Gastrointestinal tract | Bleeding | Esophagus | Literature reviews | Queens | Endoscopes | Pain | Computed tomography | Thermal injury | Gastrointestinal system | Endoscopy | Rice
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12. Full Text Inter‐genotypic recombinant hepatitis C virus strains in Japan noted by discrepancies between immunoassay and sequencing
by Hoshino, Hiromi and Hino, Kunihiko and Miyakawa, Hiroshi and Takahashi, Kazuaki and Akbar, Sheikh Mohammad Fazle and Mishiro, Shunji
Journal of Medical Virology, ISSN 0146-6615, 07/2012, Volume 84, Issue 7, pp. 1018 - 1024
Genetic recombination plays a significant role in the survival and evolution of hepatitis C virus (HCV), but methodological limitations have hindered the... 
serogroup | HCV recombination | Japan | genotype | Genotype | Serogroup | THERAPY | VIROLOGY | INFECTION | Immunoassay | Japan - epidemiology | Hepacivirus - immunology | Humans | Middle Aged | Open Reading Frames | Hepacivirus - genetics | Hepatitis C, Chronic - virology | Molecular Sequence Data | Viral Nonstructural Proteins - genetics | Male | Sequence Analysis, DNA | Molecular Epidemiology | Recombination, Genetic | Viral Core Proteins - genetics | Female | Aged | Hepatitis C, Chronic - epidemiology | Genotype & phenotype | Hepatitis | Amino acid sequence
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13. Full Text Hepatitis E virus infection in wild mongooses of Okinawa, Japan: Demonstration of anti-HEV antibodies and a full-genome nucleotide sequence
by Nakamura, Masaji and Takahashi, Kazuaki and Taira, Katsuya and Taira, Masakatsu and Ohno, Atsushi and Sakugawa, Hiroshi and Arai, Masahiro and Mishiro, Shunji
Hepatology Research, ISSN 1386-6346, 2006, Volume 34, Issue 3, pp. 137 - 140
Hepatitis E virus (HEV), a single-strand RNA virus, has been recovered not only from human beings but also from various species of animals. Here we report our... 
Single-stranded RNA virus | Interspecies transmission | Zoonosis | Hepatitis E virus (HEV) | Mongoose | DEER | single-stranded RNA virus | hepatitis E virus (HEV) | interspecies transmission | mongoose | SWINE | GASTROENTEROLOGY & HEPATOLOGY | zoonosis
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14. Recent progress in the research of Eosinophilic GastroIntestinal Diseases (EGIDs)
by Mishiro, Tsuyoshi and Ishimura, Norihisa and Ishihara, Shunji and Kinoshita, Yoshikazu
Nihon yakurigaku zasshi. Folia pharmacologica Japonica, ISSN 0015-5691, 2018, Volume 152, Issue 4, p. 175
Eosinophilic esophagitis (EoE) and eosinophilic gastroenteritis (EGE), which are included in eosinophilic gastrointestinal disorders (EGIDs), are allergic... 
Eosinophilia - pathology | Gastritis - diagnosis | Enteritis - diagnosis | Eosinophilic Esophagitis - diagnosis | Gastritis - pathology | Humans | Eosinophilic Esophagitis - pathology | Enteritis - pathology | Eosinophilia - diagnosis
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15. Recent progress in the research of Eosinophilic GastroIntestinal Diseases (EGIDs)
by Mishiro, Tsuyoshi and Mishiro, Tsuyoshi and Ishimura, Norihisa and Ishihara, Shunji and Kinoshita, Yoshikazu
Nihon yakurigaku zasshi. Folia pharmacologica Japonica, ISSN 0015-5691, 2018, Volume 152, Issue 4, pp. 175 - 180
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16. Full Text A Subclone of HuH-7 with Enhanced Intracellular Hepatitis C Virus Production and Evasion of Virus Related-Cell Cycle Arrest
by Murayama, Asako and Sugiyama, Nao and Yoshimura, Seiko and Ishihara-Sugano, Mitsuko and Masaki, Takahiro and Kim, Sulyi and Wakita, Takaji and Mishiro, Shunji and Kato, Takanobu
PLoS ONE, ISSN 1932-6203, 12/2012, Volume 7, Issue 12, p. e52697
Hepatitis C virus (HCV) cell culture system with JFH-1 strain and HuH-7 cells enabled us to produce infectious HCV particles in vitro, and such system is... 
NON-A | RNA REPLICATION | GENOTYPE 1A | MULTIDISCIPLINARY SCIENCES | DOWN-REGULATION | S-PHASE | INFECTION | EXPRESSION | GENOME | LINES | PROGRESSION | Cell Line | Cell Cycle Checkpoints | Virus Replication | Humans | Gene Expression Regulation | Genotype | Hepacivirus - physiology | Viral Load | Infection | Vaccines | RNA | Hepatitis C virus | Analysis | Cell cycle | Cell culture | Laboratories | Research & development--R&D | Cloning | Particulates | Viruses | Genomes | RNA polymerase | Kinases | Ribonucleic acid--RNA | Virology | Proteins | Hepatitis | Liver cancer | Genotype & phenotype | Dilution | Cell growth | Infectious diseases | Transfection | Replication | Intracellular | Hepatitis C | Research & development | Ribonucleic acid | R&D
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17. Full Text Dysgeusia in a Patient with Guillain-Barré Syndrome Associated with Acute Hepatitis E: A Case Report and Literature Review
by Higuchi, Masa-aki and Fukae, Jiro and Tsugawa, Jun and Ouma, Shinji and Takahashi, Kazuaki and Mishiro, Shunji and Tsuboi, Yoshio
Internal Medicine, ISSN 0918-2918, 2015, Volume 54, Issue 12, pp. 1543 - 1546
Guillain-Barré syndrome (GBS) is usually triggered by viral or bacterial infection. In addition, it was recently reported that infection with hepatitis E virus... 
hepatitis E | IVIg | dysgeusia | Guillain-Barré syndrome | muscle weakness | Guillain-barré syndrome | Hepatitis E | Muscle weakness | Dysgeusia | MEDICINE, GENERAL & INTERNAL | NORTHERN CHINA | E INFECTION | Guillain-Barre syndrome | E VIRUS | TASTE | DISORDERS | Dysgeusia - virology | Acute Disease | Hepatitis E - drug therapy | Guillain-Barre Syndrome - drug therapy | Humans | Middle Aged | Male | RNA, Viral - blood | Hepatitis E virus - genetics | Hepatitis E - diagnosis | Paralysis - complications | Guillain-Barre Syndrome - diagnosis | Guillain-Barre Syndrome - immunology | Immunoglobulins, Intravenous - therapeutic use | Paralysis - virology | Hepatitis E - immunology | Paralysis - physiopathology | Odds Ratio | Hepatitis E virus - isolation & purification | Immunologic Factors - therapeutic use
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18. Full Text Diagnosis and treatment of eosinophilic esophagitis in Japan
by Kinoshita, Yoshikazu and Ishimura, Norihisa and Mishiro, Tsuyoshi and Ishihara, Shunji and Adachi, Kyoichi
Esophagus, ISSN 1612-9059, 1/2017, Volume 14, Issue 1, pp. 66 - 75
Patients in Japan affected by eosinophilic esophagitis (EoE), considered to be a dietary allergen related chronic esophageal disease, are slowly increasing.... 
Allergy | Medicine & Public Health | Gastroenterology | Esophagitis | Thoracic Surgery | Surgical Oncology | Gastric acid | Proton pump inhibitor | Atopy | ADULTS | CLINICAL-FEATURES | PREVALENCE | GASTROENTERITIS | CHILDREN | THERAPY | GASTROESOPHAGEAL-REFLUX DISEASE | GASTROINTESTINAL DISORDERS | GASTROENTEROLOGY & HEPATOLOGY | ASSOCIATION | ENDOSCOPIC FINDINGS | Medical colleges | Care and treatment | Corticosteroids | Diagnosis
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