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1. Full Text Randomised controlled trial of long-term maintenance corticosteroid therapy in patients with autoimmune pancreatitis
by Masamune, Atsushi and Nishimori, Isao and Kikuta, Kazuhiro and Tsuji, Ichiro and Mizuno, Nobumasa and Iiyama, Tatsuo and Kanno, Atsushi and Tachibana, Yuichi and Ito, Tetsuhide and Kamisawa, Terumi and Uchida, Kazushige and Hamano, Hideaki and Yasuda, Hiroaki and Sakagami, Junichi and Mitoro, Akira and Taguchi, Masashi and Kihara, Yasuyuki and Sugimoto, Hiroyuki and Hirooka, Yoshiki and Yamamoto, Satoshi and Inui, Kazuo and Inatomi, Osamu and Andoh, Akira and Nakahara, Kazuyuki and Miyakawa, Hiroyuki and Hamada, Shin and Kawa, Shigeyuki and Okazaki, Kazuichi and Shimosegawa, Tooru and Res Comm Intractable Pancreas Dis and Research Committee of Intractable Pancreas Diseases in Japan
Gut, ISSN 0017-5749, 03/2017, Volume 66, Issue 3, pp. 487 - 494
autoimmune disease | Pancreatic disease | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Prednisolone - adverse effects | Recurrence | Prednisolone - administration & dosage | Follow-Up Studies | Humans | Middle Aged | Male | Pancreatitis - drug therapy | Withholding Treatment | Disease-Free Survival | Anti-Inflammatory Agents - adverse effects | Time Factors | Anti-Inflammatory Agents - administration & dosage | Female | Aged | Maintenance Chemotherapy | Autoimmune Diseases - drug therapy | Usage | Care and treatment | Corticosteroids | Pancreatic diseases | Diagnosis | Patients | Health aspects | Studies | Disease | Pancreatic cancer | Index Medicus | Abridged Index Medicus
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2. Covered self-expandable metal stents with an anti-migration system improve patency duration without increased complications compared with uncovered stents for distal biliary obstruction caused by pancreatic carcinoma: A randomized multicenter trial
by Kitano, Masayuki and Yamashita, Yukitaka and Tanaka, Kiyohito and Konishi, Hideyuki and Yazumi, Shujiro and Nakai, Yoshitaka and Nishiyama, Osamu and Uehara, Hiroyuki and Mitoro, Akira and Sanuki, Tsuyoshi and Takaoka, Makoto and Koshitani, Tatsuya and Arisaka, Yoshifumi and Shiba, Masatsugu and Hoki, Noriyuki and Sato, Hideki and Sasaki, Yuichi and Sato, Masako and Hasegawa, Kazunori and Kawabata, Hideaki and Okabe, Yoshihiro and Mukai, Hidekazu
The American journal of gastroenterology, ISSN 0002-9270, 11/2013, Volume 108, Issue 11, pp. 1713 - 1722
Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Prosthesis Implantation | Cholestasis - mortality | Carcinoma - surgery | Humans | Middle Aged | Pancreatic Neoplasms - surgery | Carcinoma - mortality | Male | Survival Rate | Treatment Outcome | Cholestasis - surgery | Carcinoma - complications | Prosthesis Failure | Cholestasis - etiology | Aged, 80 and over | Female | Aged | Pancreatic Neoplasms - mortality | Pancreatic Neoplasms - complications | Stents
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3. Full Text Predictive parameter of tolvaptan effectiveness in cirrhotic ascites
by Kawaratani, Hideto and Fukui, Hiroshi and Moriya, Kei and Noguchi, Ryuichi and Namisaki, Tadashi and Uejima, Masakazu and Kitade, Mitsuteru and Takeda, Kosuke and Okura, Yasushi and Kaji, Kosuke and Nishimura, Norihisa and Takaya, Hiroaki and Aihara, Yousuke and Sawada, Yasuhiko and Sato, Shinya and Seki, Kenichiro and Mitoro, Akira and Yamao, Junichi and Yoshiji, Hitoshi
Hepatology research, ISSN 1386-6346, 08/2017, Volume 47, Issue 9, pp. 854 - 861
tolvaptan | blood urea nitrogen | hepatic ascites | urine sodium concentration | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Medical research | Urea | Alcoholism | Analysis | Body weight | Medicine, Experimental | Diuretics | Hepatitis C | Ascites | Liver cirrhosis | Urine | Drug abuse | Liver | Pleural effusion | Hepatocellular carcinoma | Body weight loss | Aldosterone | Thrombosis | Vasopressin | Cirrhosis | Hepatitis | Renin | Portal vein | Hepatitis B
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4. Full Text Rifaximin ameliorates hepatic encephalopathy and endotoxemia without affecting the gut microbiome diversity
by Kosuke Kaji Hiroaki Takaya Soichiro Saikawa Masanori Furukawa Shinya Sato Hideto Kawaratani Mitsuteru Kitade Kei Moriya Tadashi Namisaki Takemi Akahane Akira Mitoro Hitoshi Yoshiji
World journal of gastroenterology : WJG, ISSN 1007-9327, 2017, Volume 23, Issue 47, pp. 8355 - 8366
Rifaximin | Endotoxin | Gut microbiome | Liver cirrhosis | Hepatic encephalopathy | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Endotoxins - blood | Humans | Middle Aged | Male | Gastrointestinal Microbiome - physiology | Hepatic Encephalopathy - drug therapy | Case-Control Studies | Anti-Bacterial Agents - therapeutic use | Feces - microbiology | Rifamycins - therapeutic use | Aged, 80 and over | Female | Hepatic Encephalopathy - etiology | Liver Cirrhosis - complications | Endotoxemia - drug therapy | Ammonia - blood | Ammonia - toxicity | Treatment Outcome | Endotoxemia - etiology | Liver Cirrhosis - blood | Cognition - drug effects | Neuropsychological Tests | Gastrointestinal Microbiome - drug effects | Rifamycins - pharmacology | Hepatic Encephalopathy - blood | Aged | Anti-Bacterial Agents - pharmacology | Endotoxins - toxicity | Index Medicus | Case Control Study
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5. Full Text Combining probiotics and an angiotensin‐II type 1 receptor blocker has beneficial effects on hepatic fibrogenesis in a rat model of non‐alcoholic steatohepatitis
by Sawada, Yasuhiko and Kawaratani, Hideto and Kubo, Takuya and Fujinaga, Yukihisa and Furukawa, Masanori and Saikawa, Soichiro and Sato, Shinya and Seki, Kenichiro and Takaya, Hiroaki and Okura, Yasushi and Kaji, Kosuke and Shimozato, Naotaka and Mashitani, Tsuyoshi and Kitade, Mitsuteru and Moriya, Kei and Namisaki, Tadashi and Akahane, Takemi and Mitoro, Akira and Yamao, Junichi and Yoshiji, Hitoshi
Hepatology research, ISSN 1386-6346, 03/2019, Volume 49, Issue 3, pp. 284 - 295
non‐alcoholic steatohepatitis | probiotic | hepatic fibrosis | angiotensin‐II type 1 receptor blocker (ARB) | intestinal tight junction | angiotensin-II type 1 receptor blocker (ARB) | non-alcoholic steatohepatitis | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Probiotics | Liver diseases | Microbiota (Symbiotic organisms) | Choline | Liver | Angiotensin | Amino acids | Bone morphogenetic proteins | Permeability | Mitogens | Stellate cells | Animal models | Digestive system | Transforming growth factor | TLR4 protein | Lipopolysaccharides | Microbiota | Fatty liver | Diet | Intestine | Rodents | Fibrosis | Toll-like receptors | Intestinal microflora | Digestive tract
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6. Full Text HMGA2 is a driver of tumor metastasis
by Morishita, Asahiro and Zaidi, M. Raza and Mitoro, Akira and Sankarasharma, Devipriya and Szabolcs, Matthias and Okada, Yasunori and D'Armiento, Jeanine and Chada, Kiran
Cancer research (Chicago, Ill.), ISSN 0008-5472, 07/2013, Volume 73, Issue 14, pp. 4289 - 4299
Life Sciences & Biomedicine | Oncology | Science & Technology | Biological and medical sciences | Multiple tumors. Solid tumors. Tumors in childhood (general aspects) | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Tumors | Receptors, Transforming Growth Factor beta - genetics | Epithelial Cells - metabolism | Signal Transduction | Epithelial-Mesenchymal Transition - physiology | HCT116 Cells | Humans | Protein-Serine-Threonine Kinases - genetics | Epithelial Cells - pathology | Cell Movement - genetics | Cell Movement - physiology | HT29 Cells | Neoplasm Metastasis | Animals | Transforming Growth Factor beta - genetics | HMGA2 Protein - metabolism | MCF-7 Cells | Receptors, Transforming Growth Factor beta - metabolism | HMGA2 Protein - genetics | Cell Line, Tumor | Female | Mice | Transforming Growth Factor beta - metabolism | Protein-Serine-Threonine Kinases - metabolism | Index Medicus | epithelial-mesenchymal transition (EMT) | TGFβ type II receptor (TGFβRII) | High-mobility group A2 (HMGA2) | invasive front | metastasis
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7. Full Text Atorvastatin Augments Gemcitabine-Mediated Anti-Cancer Effects by Inhibiting Yes-Associated Protein in Human Cholangiocarcinoma Cells
by Kitagawa, Koh and Moriya, Kei and Kaji, Kosuke and Saikawa, Soichiro and Sato, Shinya and Nishimura, Norihisa and Namisaki, Tadashi and Akahane, Takemi and Mitoro, Akira and Yoshiji, Hitoshi
International journal of molecular sciences, ISSN 1661-6596, 10/2020, Volume 21, Issue 20, p. 7588
Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Index Medicus | TEAD transcriptional activation | yes-associated protein | gemcitabine | HMG-CoA reductase | atorvastatin | cholangiocarcinoma
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8. Full Text Blocking development of liver fibrosis augments hepatic progenitor cell‐derived liver regeneration in a mouse chronic liver injury model
by Kitade, Mitsuteru and Kaji, Kosuke and Nishimura, Norihisa and Seki, Kenichiro and Nakanishi, Keisuke and Tsuji, Yuki and Sato, Shinya and Saikawa, Soichiro and Takaya, Hiroaki and Kawaratani, Hideto and Namisaki, Tadashi and Moriya, Kei and Mitoro, Akira and Yoshiji, Hitoshi
Hepatology research, ISSN 1386-6346, 09/2019, Volume 49, Issue 9, pp. 1034 - 1045
hepatic progenitor cell | NOTCH | hepatic stellate cell | Jagged1 | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Immunohistochemistry | Somatotropin | Liver diseases | Analysis | Liver | Fibrosis | Angiotensin | Muscle proteins | Stellate cells | Epithelial cells | Smooth muscle | Cell differentiation | Progenitor cells | Hepatocytes | Actin | Stem cells | Extracellular matrix | Jagged1 protein | Angiotensin II | Bile
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9. Full Text Angiotensin receptor blockade attenuates cholangiocarcinoma cell growth by inhibiting the oncogenic activity of Yes-associated protein
by Saikawa, Soichiro and Kaji, Kosuke and Nishimura, Norihisa and Seki, Kenichiro and Sato, Shinya and Nakanishi, Keisuke and Kitagawa, Koh and Kawaratani, Hideto and Kitade, Mitsuteru and Moriya, Kei and Namisaki, Tadashi and Mitoro, Akira and Yoshiji, Hitoshi
Cancer letters, ISSN 0304-3835, 10/2018, Volume 434, pp. 120 - 129
Yes-associated protein | G protein-coupled receptor | Angiogenesis | Angiotensin receptor blocker | Cholangiocarcinoma | Life Sciences & Biomedicine | Oncology | Science & Technology | Medical colleges | Chemotherapy | Growth | Angiotensin | Stem cells | G proteins | Aldosterone | Membrane proteins | Cancer | Index Medicus
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10. Full Text Combined effect of a farnesoid X receptor agonist and dipeptidyl peptidase‐4 inhibitor on hepatic fibrosis
by Shimozato, Naotaka and Namisaki, Tadashi and Kaji, Kosuke and Kitade, Mitsuteru and Okura, Yasushi and Sato, Shinya and Moriya, Kei and Seki, Kenichiro and Kawaratani, Hideto and Takaya, Hiroaki and Sawada, Yasuhiko and Saikawa, Soichiro and Nakanishi, Keisuke and Furukawa, Masanori and Fujinaga, Yukihisa and Kubo, Takuya and Asada, Kiyoshi and Kitagawa, Koh and Tsuji, Yuki and Kaya, Daisuke and Ozutsumi, Takahiro and Akahane, Takemi and Mitoro, Akira and Yoshiji, Hitoshi
Hepatology research, ISSN 1386-6346, 10/2019, Volume 49, Issue 10, pp. 1147 - 1161
obeticholic acid | non‐alcoholic steatohepatitis | hepatic stellate cell | sitagliptin | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Tissue inhibitor of metalloproteinases | Stellate cells | Phosphorylation | Procollagen | Peptidase | Liver | Hydroxyproline | TLR4 protein | Permeability | Matrix metalloproteinase | Gene expression | Lipopolysaccharides | Acids | Diet | Intestine | Choline | Fibrosis | Toll-like receptors | Agonists | Metalloproteinase | Endotoxemia
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11. Full Text Platelet hyperaggregability is associated with decreased ADAMTS13 activity and enhanced endotoxemia in patients with acute cholangitis
by Takaya, Hiroaki and Kawaratani, Hideto and Kubo, Takuya and Seki, Kenichiro and Sawada, Yasuhiko and Kaji, Kosuke and Okura, Yasushi and Takeda, Kosuke and Kitade, Mitsuteru and Moriya, Kei and Namisaki, Tadashi and Mitoro, Akira and Matsumoto, Masanori and Fukui, Hiroshi and Yoshiji, Hitoshi
Hepatology research, ISSN 1386-6346, 02/2018, Volume 48, Issue 3, pp. E52 - E60
cytokine | acute cholangitis | ADAMTS13 | EAA | VWF | endotoxin | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Antigens | Enzymes | Medical research | Interleukins | Von Willebrand factor | Medicine, Experimental | Enzyme-linked immunosorbent assay | Interleukin 6 | Tumor necrosis factor | Cholangitis | Tumor necrosis factor-TNF | Inflammation | Platelets | Endotoxemia | Interleukin 8
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