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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2010, Volume 107, Issue 43, pp. 18439 - 18444
Very long-chain fatty acids (VLCFAs) exert a variety of cellular functions and are associated with numerous diseases. However, the precise pathway behind their... 
Enzymes | Messenger RNA | Substrate specificity | HeLa cells | Small interfering RNA | Ceramides | Lipids | Sphingolipids | Mammals | Fatty acids | Monounsaturated fatty acid | Polyunsaturated fatty acid | Acyl-CoA | Lipid metabolism | Saturated fatty acid | acyl-CoA | CERAMIDE SYNTHASE 2 | MULTIDISCIPLINARY SCIENCES | lipid metabolism | IDENTIFICATION | SACCHAROMYCES-CEREVISIAE | MASS-SPECTROMETRY | saturated fatty acid | CHAIN FATTY-ACIDS | ELONGATION | BIOSYNTHESIS | GENE FAMILY | SKIN FUNCTION | monounsaturated fatty acid | polyunsaturated fatty acid | ADIPOSE-TISSUE | Acyl Coenzyme A - biosynthesis | Sphingolipids - biosynthesis | Sphingolipids - chemistry | RNA, Small Interfering - genetics | Acetyltransferases - metabolism | Membrane Microdomains - metabolism | Saccharomyces cerevisiae - genetics | Humans | Substrate Specificity | Male | DNA Primers - genetics | RNA, Messenger - metabolism | Acetyltransferases - genetics | Gene Knockdown Techniques | Saccharomyces cerevisiae - metabolism | Tissue Distribution | Base Sequence | Acetyltransferases - antagonists & inhibitors | Female | Membrane Proteins - metabolism | Sphingosine N-Acyltransferase - metabolism | Recombinant Proteins - metabolism | Cell Line | Tumor Suppressor Proteins - metabolism | Fatty Acids - chemistry | RNA, Messenger - genetics | Recombinant Proteins - genetics | Acyl Coenzyme A - chemistry | HeLa Cells | In Vitro Techniques | Fatty Acids - biosynthesis | Research | Molecular biology | Health aspects | Biological Sciences
Journal Article
Journal Article
Bioscience, Biotechnology, and Biochemistry, ISSN 0916-8451, 01/2013, Volume 77, Issue 1, pp. 194 - 197
We have previously reported that phytoceramide and phytosphingosine (PHS) stimulated the transcriptional activity of peroxisome proliferator-activated receptor... 
PPAR | phytoceramide | sphingolipid δ-desaturase/C4-hydroxylase isoform 2 (DES2) | sphingolipid | phytosphingosine | Sphingolipid | Phytosphingosine | Sphingolipid δ-desaturase/C4- hydroxylase isoform 2 (DES2) | Phytoceramide | CHOLESTEROL | BIOCHEMISTRY & MOLECULAR BIOLOGY | FOOD SCIENCE & TECHNOLOGY | SPHINGOLIPIDS | OBESITY | METABOLISM | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | SPHINGOMYELIN | LIVER | MICE | CHEMISTRY, APPLIED | RECEPTORS | sphingolipid delta-desaturase/C4-hydroxylase isoform 2 (DES2) | Tumor Necrosis Factor-alpha - metabolism | Tumor Necrosis Factor-alpha - genetics | Body Weight - drug effects | Diet, High-Fat - adverse effects | Diabetes Mellitus, Type 2 - diet therapy | Diabetes Mellitus, Type 2 - metabolism | PPAR gamma - metabolism | Glucose Intolerance - prevention & control | Multienzyme Complexes - deficiency | Sphingosine - administration & dosage | Adiponectin - genetics | Adiponectin - metabolism | Diabetes Mellitus, Type 2 - etiology | Chemokine CCL2 - metabolism | Oxidoreductases - deficiency | PPAR gamma - genetics | Ceramides - administration & dosage | Intestine, Small - chemistry | Gene Expression | Glucose Tolerance Test | Administration, Oral | Oxidoreductases - genetics | Liver - metabolism | Chemokine CCL2 - genetics | Multienzyme Complexes - genetics | Liver - chemistry | Mice, Knockout | Sphingosine - analogs & derivatives | Animals | Glucose - metabolism | Mice | Intestine, Small - metabolism
Journal Article
Cell Biology International, ISSN 1065-6995, 07/2018, Volume 42, Issue 7, pp. 823 - 831
Sphingomyelin (SM) is required for cells to proliferate, but the reason is not fully understood. In order to asses this question, we employed a cell line, ZS,... 
mTOR | lipid microdomains | sphingomyelin | sphingomyelin synthase | amino acid | GLUT1 | MECHANISM | TRANSPORTER EXPRESSION | CELL BIOLOGY | HAMSTER OVARY CELLS | AVAILABILITY | GROWTH | SYNTHASES | RESISTANCE | SMS1 | CAVEOLIN-1 | TOR protein | Cyclodextrin | Sphingomyelin | Amino acids | Embryo fibroblasts | Rapamycin | Embryos
Journal Article
BBA - Molecular and Cell Biology of Lipids, ISSN 1388-1981, 05/2014, Volume 1841, Issue 5, pp. 793 - 798
Journal Article
Cell Biology International, ISSN 1065-6995, 07/2018, Volume 42, Issue 7, pp. 823 - 831
Journal Article
Journal Article
Journal Article