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JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2011, Volume 58, Issue 16, pp. 1715 - 1727
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 12, p. e15697
Background: The aged brain exhibits a loss in gray matter and a decrease in spines and synaptic densities that may represent a sequela for neurodegenerative... 
ISCHEMIC TOLERANCE | RICH MEMBRANE DOMAINS | AGE-RELATED-CHANGES | ALZHEIMERS-DISEASE | NEUROTROPHIC FACTOR | LIPID RAFTS | BIOLOGY | SPINAL-CORD-INJURY | AMYLOID PRECURSOR PROTEIN | RAT-BRAIN | NEUROBLASTOMA-CELLS | Membrane Microdomains | Signal Transduction | Neurodegenerative Diseases - metabolism | Synaptosomes - metabolism | Mice, Knockout | Brain - metabolism | Caveolin 1 - metabolism | Hippocampus - metabolism | Animals | Synapses - metabolism | Time Factors | Alzheimer Disease - metabolism | Aging | Mice | Neurons - metabolism | Nerve Degeneration | Disease Models, Animal | Brain | Nervous system diseases | Neurons | Analysis | Lipids | Alzheimer's disease | Neurophysiology | Protein binding | Caveolin-1 | Synaptogenesis | Rafts | Nervous system | Lipid rafts | Glutamic acid receptors | α-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors | Substantia grisea | Proteins | Cerebrovascular system | Genotype & phenotype | Signal transduction | Reperfusion | Ischemia | Neurodegeneration | Transgenic animals | Older people | Rodents | Degeneration | Synaptosomes | Localization | Stroke | Middle age | Neurodegenerative diseases | Caveolin | N-Methyl-D-aspartic acid receptors | Cholesterol | Neurological diseases | Signaling | Brain research | Gliosis | Glycosphingolipids | Tau protein | Plasma membranes | Sphingomyelin | Anesthesiology | Respiration | Postsynaptic density proteins | Alzheimers disease | Synapses | Hippocampus | Apoptosis | Dementia
Journal Article
Cold Spring Harbor Protocols, ISSN 1940-3402, 04/2012, Volume 7, Issue 4, pp. 453 - 456
Journal Article
Journal Article
Nature Neuroscience, ISSN 1097-6256, 11/2015, Volume 18, Issue 11, pp. 1617 - 1622
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2012, Volume 109, Issue 9, pp. 3377 - 3382
Lesch-Nyhan disease (LND) is an X-linked genetic disorder caused by mutations of the hypoxanthine guanine phosphoribosyltransferase (HPRJ) purine biosynthesis... 
Purines | Receptors | Messenger RNA | Purinergic receptors | Induced pluripotent stem cells | Neurons | Stem cells | Cell lines | Embryonic stem cells | Cells | Neurodevelopment | Neurotransmitters | PATHWAYS | MULTIDISCIPLINARY SCIENCES | NEURONAL DIFFERENTIATION | DISORDERS | BETA-CATENIN | NUCLEOTIDE | LESCH-NYHAN-DISEASE | neurodevelopment | neurotransmitters | GROWTH | CENTRAL-NERVOUS-SYSTEM | RECEPTORS | EXPRESSION | RNA, Small Interfering - genetics | Fibroblasts - enzymology | Glycogen Synthase Kinase 3 - physiology | MAP Kinase Signaling System - physiology | Humans | Glycogen Synthase Kinase 3 beta | Male | Gene Knockdown Techniques | Adenosine Triphosphate - pharmacology | Receptors, Purinergic P2Y1 - genetics | Lesch-Nyhan Syndrome - enzymology | Lentivirus - genetics | Receptors, Purinergic P2Y1 - physiology | Cell Line | Mitogen-Activated Protein Kinase 1 - physiology | Purines - metabolism | RNA, Messenger - genetics | Pluripotent Stem Cells - enzymology | Genes, Essential | beta Catenin - metabolism | Genetic Vectors - genetics | Mitogen-Activated Protein Kinase 3 - physiology | Purinergic P2Y Receptor Agonists - pharmacology | Neurogenesis - physiology | Hypoxanthine Phosphoribosyltransferase - physiology | Development and progression | Lesch-Nyhan syndrome | Genetic aspects | Health aspects | Cellular control mechanisms | Biological Sciences
Journal Article
Journal of Cancer Research and Clinical Oncology, ISSN 0171-5216, 8/2017, Volume 143, Issue 8, pp. 1395 - 1407
Journal Article
Journal Article
Circulation, ISSN 0009-7322, 11/2018, Volume 138, Issue Suppl_1 Suppl 1, pp. A14281 - A14281
Heart failure with preserved ejection fraction (HFpEF) comprises up to 50% of HF and has increased prevalence among older patients. However, current clinical... 
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2012, Volume 7, Issue 3, p. e32581
Journal Article
PeerJ, ISSN 2167-8359, 2017, Volume 2017, Issue 10, p. e3905
Small interference RNA has been widely used to suppress gene expression. Three different short hairpin RNAs (shRNAs) against dopamine D1 receptor (Drd1),... 
White matter degeneration | Innate immunity | Neuroinflammation | Drd1 | shRNA | Microglial activation | RNA INTERFERENCE | CELLS | ACTIVATION | DNA METHYLATION | MULTIDISCIPLINARY SCIENCES | MOUSE | INDUCTION | INTERFERON RESPONSE | DOPAMINE | EXPRESSION | VECTORS | Nervous system diseases | Multiple sclerosis | Models | Mice | Gene expression | Diseases
Journal Article