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2016, 4th edition., World Health Organization classification of tumours, ISBN 9789283224372, 356 pages
Book
International Journal of Cancer, ISSN 0020-7136, 07/2016, Volume 139, Issue 2, pp. 396 - 403
In our study, we demonstrate that ccRCC cell lines with impaired function of pVHL to degrade HIFα express elevated levels of PD‐L1. In vitro analysis provided... 
ccRCC | HIF | pVHL | PD‐L1 | PD-L1 | CANCER-CELLS | PATHWAYS | ANTIBODY | IDENTIFICATION | HIF1-ALPHA | ESCAPE | TUMOR-SUPPRESSOR PVHL | THERAPY | ONCOLOGY | MUTATIONS | BLOCKADE | Immunohistochemistry | Gene Expression | Kidney Neoplasms - genetics | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Humans | Gene Expression Regulation, Neoplastic | Gene Silencing | Carcinoma, Renal Cell - genetics | Kidney Neoplasms - metabolism | B7-H1 Antigen - genetics | Case-Control Studies | Carcinoma, Renal Cell - metabolism | B7-H1 Antigen - metabolism | B7-H1 Antigen - blood | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Cell Line, Tumor | Von Hippel-Lindau Tumor Suppressor Protein - genetics | Mutation | Analysis | Cancer | Chemotherapy | Rodents | Kidney cancer | Hypoxia | Ligands | T cell receptors | Apoptosis | Drugs | Biotechnology | Hypoxia-inducible factor 1 | Correlation | Target recognition | PD-1 protein | Genes | Lymphocytes T | In vitro testing | Drug delivery | Inactivation | Immunosuppressive agents | Degradation | Inhibition | Hypoxia-inducible factors | Deactivation | Mortality | Immunosurveillance | Tumor cell lines | Patients | Surveillance | Cell death | PD-L1 protein | Reagents | VHL protein | Aberration | Neoplasia | Clear cell-type renal cell carcinoma | Tumors | Kidney transplantation | Index Medicus
Journal Article
Breast Cancer Research and Treatment, ISSN 0167-6806, 11/2010, Volume 124, Issue 2, pp. 497 - 507
Trastuzumab has conferred significant clinical benefits in HER-2-positive breast carcinomas. HER-2 status is determined by immunohistochemistry (IHC) and/or... 
Medicine & Public Health | Cost–effectiveness | Oncology | Adjuvant | Breast cancer | Predictive tests | Trastuzumab | Cost-effectiveness | ADJUVANT CHEMOTHERAPY | 1ST-LINE TREATMENT | EFFICACY | SAFETY | PROGNOSIS | MONOCLONAL-ANTIBODY | DOCETAXEL | HER-2 STATUS | LOCAL RECURRENCE | ONCOLOGY | TRASTUZUMAB THERAPY | Drug Costs | Predictive Value of Tests | Markov Chains | Receptor, ErbB-2 - genetics | Humans | Antibodies, Monoclonal - therapeutic use | Antineoplastic Agents - therapeutic use | Models, Economic | Mass Screening - methods | Antibodies, Monoclonal, Humanized | Breast Neoplasms - chemistry | Sensitivity and Specificity | Female | Chemotherapy, Adjuvant | Immunohistochemistry - economics | Quality-Adjusted Life Years | In Situ Hybridization, Fluorescence - economics | Biomarkers, Tumor - analysis | Mass Screening - economics | National Health Programs - economics | Treatment Outcome | Breast Neoplasms - drug therapy | Switzerland | Antineoplastic Agents - economics | Health Care Costs | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Cost-Benefit Analysis | Biomarkers, Tumor - genetics | Receptor, ErbB-2 - analysis | Antibodies, Monoclonal - economics | Immunohistochemistry | Cancer patients | Epidermal growth factor | Analysis | Adjuvant treatment | Economic aspects | Fluorescence | Cost benefit analysis | Cancer | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 09/2003, Volume 425, Issue 6955, pp. 307 - 311
Journal Article
Nature Genetics, ISSN 1061-4036, 06/2012, Volume 44, Issue 6, pp. 685 - 689
Journal Article
by Peifer, Martin and Fernández-Cuesta, Lynnette and Sos, Martin L and George, Julie and Seidel, Danila and Kasper, Lawryn H and Plenker, Dennis and Leenders, Frauke and Sun, Ruping and Zander, Thomas and Menon, Roopika and Koker, Mirjam and Dahmen, Ilona and Müller, Christian and Di Cerbo, Vincenzo and Schildhaus, Hans-Ulrich and Altmüller, Janine and Baessmann, Ingelore and Becker, Christian and De Wilde, Bram and Vandesompele, Jo and Böhm, Diana and Ansén, Sascha and Gabler, Franziska and Wilkening, Ines and Heynck, Stefanie and Heuckmann, Johannes M and Lu, Xin and Carter, Scott L and Cibulskis, Kristian and Banerji, Shantanu and Getz, Gad and Park, Kwon-Sik and Rauh, Daniel and Grütter, Christian and Fischer, Matthias and Pasqualucci, Laura and Wright, Gavin and Wainer, Zoe and Russell, Prudence and Petersen, Iver and Chen, Yuan and Stoelben, Erich and Ludwig, Corinna and Schnabel, Philipp and Hoffmann, Hans and Muley, Thomas and Brockmann, Michael and Engel-Riedel, Walburga and Muscarella, Lucia A and Fazio, Vito M and Groen, Harry and Timens, Wim and Sietsma, Hannie and Thunnissen, Erik and Smit, Egber and Heideman, Daniëlle A. M and Snijders, Peter J. F and Cappuzzo, Federico and Ligorio, Claudia and Damiani, Stefania and Field, John and Solberg, Steinar and Brustugun, Odd Terje and Lund-Iversen, Marius and Sänger, Jörg and Clement, Joachim H and Soltermann, Alex and Moch, Holger and Weder, Walter and Solomon, Benjamin and Soria, Jean-Charles and Validire, Pierre and Besse, Benjamin and Brambilla, Elisabeth and Brambilla, Christian and Lantuejoul, Sylvie and Lorimier, Philippe and Schneider, Peter M and Hallek, Michael and Pao, William and Meyerson, Matthew and Sage, Julien and Shendure, Jay and Schneider, Robert and Büttner, Reinhard and Wolf, Jürgen and Nürnberg, Peter and Perner, Sven and Heukamp, Lukas C and Brindle, Paul K and Haas, Stefan and Thomas, Roman K
Nature Genetics, ISSN 1061-4036, 10/2012, Volume 44, Issue 10, pp. 1104 - 1110
Journal Article
Journal Article
International Journal of Cancer, ISSN 0020-7136, 07/2016, Volume 139, Issue 2, pp. 396 - 403
Journal Article
Nature Medicine, ISSN 1078-8956, 07/2017, Volume 23, Issue 7, pp. 869 - 877
Clear cell renal cell carcinomas (ccRCCs) frequently exhibit inactivation of the von Hippel-Lindau tumor-suppressor gene, VHL, and often harbor multiple... 
MEDICINE, RESEARCH & EXPERIMENTAL | ACTIVATION | TARGETED INACTIVATION | TUMOR PROGRESSION | HIF | BIOCHEMISTRY & MOLECULAR BIOLOGY | C-MYC | GENOME | CELL BIOLOGY | COMBINED DELETION | MOUSE MODEL | KIDNEY | EXPRESSION | Immunohistochemistry | Kidney Tubules, Proximal - cytology | Kidney Neoplasms - genetics | Humans | Kaplan-Meier Estimate | Carcinoma, Renal Cell - genetics | Survival Rate | Epithelial Cells | RNA, Messenger - metabolism | X-Ray Microtomography | Tumor Suppressor Protein p53 - genetics | Cilia - genetics | Animals | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Retinoblastoma Protein - genetics | Mice | Von Hippel-Lindau Tumor Suppressor Protein - genetics | Mutation | Retinoblastoma Binding Proteins - genetics | Ubiquitin-Protein Ligases - genetics | Disease Models, Animal | Transcription factors | RNA | Gene mutations | Genetic aspects | Research | DNA binding proteins | Carcinoma, Renal cell | Epithelial cells | Genes | Medical services | Inactivation | Acriflavine | Mimicry | Convergence | Gene sequencing | Alterations | Clonal deletion | Rodents | Cell cycle | Deletion | Inhibition | Hypoxia-inducible factors | Deactivation | Kidneys | Markers | Gene expression | Hypoxia | VHL protein | Neoplasia | Human behavior | Clear cell-type renal cell carcinoma | Tumors | Kidney transplantation | Cancer | Index Medicus
Journal Article