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International Journal of Hematology, ISSN 0925-5710, 8/2018, Volume 108, Issue 2, pp. 130 - 138
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 09/2019, Volume 116, Issue 36, pp. 17963 - 17969
Many neurodegenerative diseases are characterized by the accumulation of abnormal protein aggregates in the brain. In Parkinson's disease (PD), α-synuclein... 
Microbeams | Brain | Autopsies | Parkinson's disease | Neurodegenerative diseases | Fibrils | Parkinsons disease | X-ray diffraction | Synuclein | Accumulation | Lewy bodies | Neurological diseases | Diffraction patterns | Supports | Aggregates | Autopsy | Amyloid | Amyloidosis | Movement disorders | Index Medicus
Journal Article
Nihon Naika Gakkai Zasshi, ISSN 0021-5384, 03/2018, Volume 107, Issue 3, pp. 464 - 469
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 1 - 13
Parkinson’s disease (PD) is a neurodegenerative disease caused by the loss of dopaminergic neurons in the substantia nigra. A characteristic pathological... 
Proteins | Dopamine | Parkinson's disease | Neurodegenerative diseases | Substantia nigra | Antisense oligonucleotides | mRNA | Nucleic acids | Synuclein | Movement disorders | Dopamine receptors
Journal Article
Molecular Brain, ISSN 1756-6606, 2012, Volume 5, Issue 1, pp. 35 - 35
Journal Article
Nature Communications, ISSN 2041-1723, 04/2016, Volume 7, Issue 1, pp. 11067 - 11067
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2016, Volume 11, Issue 4, pp. e0153789 - e0153789
Journal Article
The Journal of neuroscience : the official journal of the Society for Neuroscience, ISSN 0270-6474, 07/2019, p. 295
Neuropathic pain is a chronic condition that occurs frequently after nerve injury and induces hypersensitivity or allodynia characterized by aberrant neuronal... 
Index Medicus
Journal Article
Journal of Cerebral Blood Flow & Metabolism, ISSN 0271-678X, 02/2010, Volume 30, Issue 2, pp. 299 - 310
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2015, Volume 10, Issue 10, pp. e0141629 - e0141629
Mutations in PLA2G6 have been proposed to be the cause of neurodegeneration with brain iron accumulation type 2. The present study aimed to clarify the... 
NEURODEGENERATIVE DISORDERS | DOCOSAHEXAENOIC ACID | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | NITRIC-OXIDE | MITOCHONDRIAL DYSFUNCTION | PLA2G6 MUTATION | RAT-BRAIN | INFANTILE NEUROAXONAL DYSTROPHY | PHENOTYPIC SPECTRUM | Group VI Phospholipases A2 - deficiency | Humans | Transcriptional Activation | Nerve Degeneration - genetics | Mitochondria - metabolism | Mitochondria - pathology | Group VI Phospholipases A2 - metabolism | Iron - metabolism | Nerve Degeneration - pathology | Mice, Knockout | Mitochondrial Membranes - metabolism | Brain - metabolism | Animals | Cation Transport Proteins - metabolism | Group VI Phospholipases A2 - genetics | Iron Regulatory Protein 2 - genetics | Mitochondrial Membranes - pathology | Brain - pathology | Cation Transport Proteins - genetics | Female | Mice | Iron Regulatory Protein 2 - metabolism | Disease Models, Animal | Influence | Cellular signal transduction | Calcium, Dietary | Phospholipases | Research | Analysis | Brain | Calcium | Disease | Metals | Homeostasis | Lipid peroxidation | Lipids | Iron | Kinases | Males | Accumulation | Western blotting | Neuroblastoma cells | Proteins | Mitochondria | Neurodegeneration | Rodents | Genetics | Degeneration | University graduates | Enzymes | Phospholipase A2 | Nutrient deficiency | siRNA | Perl | Divalent metal transporter-1 | Metabolism | Ablation | Medicine | Phospholipase | Neurology | Mutation | Laboratory animals | ATP | Transporter | Regulatory proteins | Index Medicus
Journal Article
Journal of Neuropathology and Experimental Neurology, ISSN 0022-3069, 08/2011, Volume 70, Issue 8, pp. 686 - 697
Loss-of-function mutations in the ubiquitin ligase parkin are the major cause of recessively inherited early-onset Parkinson disease (PD). Impairment of parkin... 
α-Synuclein | Neuroprotection | Adeno-associated virus | Osmotic minipump | Parkinson disease | MPTP | Parkin | UBIQUITIN LIGASE | PHOSPHORYLATION | PATHOLOGY | VIRAL VECTORS | NEUROSCIENCES | RAT MODEL | CLINICAL NEUROLOGY | CELL-DEATH | RECESSIVE JUVENILE PARKINSONISM | S-NITROSYLATION | GENE-THERAPY | MICE | alpha-Synuclein | Chromatography, High Pressure Liquid - methods | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine - administration & dosage | Humans | Microinjections - methods | Motor Activity - drug effects | Male | Green Fluorescent Proteins - genetics | Statistics as Topic | Corpus Striatum - metabolism | MPTP Poisoning - complications | Nerve Degeneration - prevention & control | Neurons - physiology | MPTP Poisoning - pathology | Oncogene Protein v-akt - metabolism | Corpus Striatum - pathology | Neurotoxins - administration & dosage | Transduction, Genetic - methods | Dopamine - metabolism | Disease Models, Animal | Mesencephalon - pathology | Mice, Inbred C57BL | Tumor Suppressor Protein p53 - metabolism | Ubiquitin-Protein Ligases - metabolism | bcl-2-Associated X Protein - metabolism | Nerve Degeneration - pathology | Gene Expression Regulation - drug effects | Rotarod Performance Test | Animals | Cell Count - methods | Analysis of Variance | MPTP Poisoning - metabolism | Signal Transduction - drug effects | Genetic Vectors - physiology | Mice | MPTP Poisoning - chemically induced | Nerve Degeneration - etiology | Ubiquitin-Protein Ligases - genetics | alpha-Synuclein - metabolism | Ubiquitin-Protein Ligases - therapeutic use | Index Medicus
Journal Article
NEUROREPORT, ISSN 0959-4965, 02/2014, Volume 25, Issue 3, pp. 146 - 146
In mouse and monkey models of Parkinson's disease (PD), we have previously shown that intracerebral injection of adeno-associated viral vector encoding parkin,... 
NEURONS | NEUROSCIENCES | MODEL
Conference Proceeding