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01/1998, ISBN 9780493804149
Dissertation
FEBS Letters, ISSN 0014-5793, 2001, Volume 502, Issue 1, pp. 21 - 24
Journal Article
Journal Article
2003
Dissertation
Nature, ISSN 0028-0836, 07/2005, Volume 436, Issue 7049, pp. 356 - 362
Journal Article
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 11/2007, Volume 27, Issue 21, pp. 7727 - 7734
Obesity and type 2 diabetes are characterized by insulin resistance. Mice lacking the protein-tyrosine phosphatase PTP1B in all tissues are hypersensitive to... 
Journal Article
The American Journal of Physiology, ISSN 0002-9513, 04/2008, Volume 294, Issue 4, p. E785
Serum retinol-binding protein (RBP4) is secreted by liver and adipocytes and is implicated in systemic insulin resistance in rodents and humans. RBP4 normally... 
Physiological aspects | Binding proteins | Research
Journal Article
American Journal of Physiology, ISSN 0193-1849, 04/2008, Volume 294, Issue 4, p. E785
  Serum retinol-binding protein (RBP4) is secreted by liver and adipocytes and is implicated in systemic insulin resistance in rodents and humans. RBP4... 
Proteins | Diet | Rodents | Biochemistry | Metabolism | Insulin | Endocrinology
Journal Article
Acta Medica Saliniana, ISSN 0350-364X, 01/2009, Volume 38, Issue 1, p. 2
Journal Article
Journal Article
American Journal of Physiology, ISSN 0193-1849, 12/2009, Volume 297, Issue 6, p. E1420
  The synthetic retinoid Fenretinide (FEN) increases insulin sensitivity in obese rodents and is in early clinical trials for treatment of insulin resistance... 
Obesity | Medical treatment | Rodents | Glucose | Comparative analysis | Chemical compounds
Journal Article
Journal Article
Biochemical Journal, ISSN 0264-6021, 09/2011, Volume 438, Issue 2, pp. 369 - 378
Obesity is associated with induction of the ER (endoplasmic reticulum)-stress response signalling and insulin resistance. PTP1B (protein tyrosine phosphatase... 
Obesity | Insulin resistance | Endoplasmic reticulum (ER) stress | Metabolic syndrome | Protein tyrosine phosphatase 1B (PTP1B) | OXIDATIVE STRESS | ER STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | protein tyrosine phosphatase 1B (PTP1B) | endoplasmic reticulum (ER) stress | INSULIN SENSITIVITY | metabolic syndrome | SIGNAL-TRANSDUCTION | GLUCOSE-HOMEOSTASIS | LEPTIN ACTION | IN-VIVO | GENE-EXPRESSION | BINDING PROTEIN-1 | insulin resistance | HEPATIC STEATOSIS | obesity | Organ Specificity - drug effects | Class Ia Phosphatidylinositol 3-Kinase - metabolism | Liver - pathology | Liver - enzymology | Humans | Protein Transport - drug effects | RNA, Messenger - metabolism | X-Box Binding Protein 1 | Gene Knockdown Techniques | DNA-Binding Proteins - metabolism | Endoplasmic Reticulum - pathology | Organ Specificity - genetics | Cell Nucleus - metabolism | Liver - drug effects | Endoplasmic Reticulum - drug effects | Gene Deletion | Eukaryotic Initiation Factor-2 - metabolism | Protein Tyrosine Phosphatase, Non-Receptor Type 1 - genetics | Stress, Physiological - drug effects | Homeostasis - drug effects | Protein-Serine-Threonine Kinases - metabolism | Endoribonucleases - metabolism | RNA, Messenger - genetics | Protein Tyrosine Phosphatase, Non-Receptor Type 1 - deficiency | Regulatory Factor X Transcription Factors | Hep G2 Cells | Obesity - pathology | Transcription Factors - metabolism | Activating Transcription Factor 6 - metabolism | Protein Tyrosine Phosphatase, Non-Receptor Type 1 - metabolism | Animals | Signal Transduction - drug effects | Tunicamycin - pharmacology | Lipid Metabolism - drug effects | Glucose - metabolism | Thapsigargin - pharmacology | Mice | Obesity - enzymology | Cell Nucleus - drug effects | ER stress | PTP1B
Journal Article
Atherosclerosis, ISSN 0021-9150, 2012, Volume 223, Issue 2, pp. 532 - 532
Journal Article
International Journal of General Medicine, ISSN 1178-7074, 2012, Volume 5, pp. 403 - 411
Retinol-binding protein 4 (RBP4) is an adipokine identified as a marker of insulin resistance in mice and humans. Protein tyrosine phosphatase 1B (PTP1B)... 
Obesity | Glucose homeostasis | BIP | ER stress | GRP94 | RBP4 | PTP1B | TTR | UPR | Insulin resistance | Diabetes | Metformin | ATF4 | Proteins | Body mass index | Stress response | metformin | glucose homeostasis | diabetes | insulin resistance | obesity
Journal Article
Proceedings of SPIE - The International Society for Optical Engineering, ISSN 0277-786X, 10/2012, Volume 8458, pp. 845827 - 845827-8
In this paper we describe the first use of Optoelectronic Tweezers (OET), an optically controlled micromanipulation method, to measure the relative stiffness... 
Obesity | Optical micromanipulation | Optoelectronic tweezers | Cell stiffness | Erythrocytes
Conference Proceeding
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