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Journal Article
Science, ISSN 0036-8075, 12/2014, Volume 346, Issue 6214, pp. 1242 - 1246
Journal Article
Science, ISSN 0036-8075, 05/2016, Volume 352, Issue 6286, pp. 725 - 729
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2015, Volume 112, Issue 48, pp. E6614 - E6623
Journal Article
Molecular Systems Biology, ISSN 1744-4292, 07/2014, Volume 10, Issue 7, pp. 733 - n/a
Journal Article
Molecular Systems Biology, ISSN 1744-4292, 08/2019, Volume 15, Issue 8, pp. e8679 - n/a
A recent study by Haapaniemi et al (2018) reported that intact p53 signaling hampers CRISPR ‐based functional genomic screens. Brown et al report good... 
Index Medicus
Journal Article
Nature Climate Change, ISSN 1758-678X, 06/2015, Volume 5, Issue 6, pp. 501 - 503
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 03/2016, Volume 7, Issue 1, p. 10955
Mitochondrial Ca2+ uptake through the recently discovered Mitochondrial Calcium Uniporter (MCU) is controlled by its gatekeeper Mitochondrial Calcium Uptake 1... 
SYSTEM | ACTIVATION | PROTEIN | RAT | LIVER-REGENERATION | MULTIDISCIPLINARY SCIENCES | CALCIUM UNIPORTER | GATEKEEPER | STRESS | MCU | PERMEABILITY TRANSITION
Journal Article
Science, ISSN 0036-8075, 2/2013, Volume 339, Issue 6119, pp. 590 - 595
Journal Article
Nature Medicine, ISSN 1078-8956, 01/2017, Volume 23, Issue 1, pp. 60 - 68
Forward genetic screens with CRISPR-Cas9 genome editing enable high-resolution detection of genetic vulnerabilities in cancer cells. We conducted genome-wide... 
MEDICINE, RESEARCH & EXPERIMENTAL | RNF43 | HUMAN-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MECHANISMS | CANCER | CELL BIOLOGY | ESSENTIAL GENES | INHIBITION | GROWTH | MUTATIONAL LANDSCAPE | WNT | RECEPTORS | Frizzled Receptors - antagonists & inhibitors | Neoplasm Transplantation | Oncogene Proteins - genetics | Pancreatic Neoplasms - metabolism | Colorectal Neoplasms - genetics | Humans | Carcinoma, Pancreatic Ductal - metabolism | Molecular Targeted Therapy | RNA, Messenger - metabolism | Carcinoma, Pancreatic Ductal - genetics | Adenocarcinoma - metabolism | Flow Cytometry | Organoids - metabolism | Clustered Regularly Interspaced Short Palindromic Repeats | Adenocarcinoma - genetics | Real-Time Polymerase Chain Reaction | Colorectal Neoplasms - metabolism | Frizzled Receptors - metabolism | Pancreatic Neoplasms - genetics | DNA-Binding Proteins - genetics | Mice, SCID | Reverse Transcriptase Polymerase Chain Reaction | Antibodies - pharmacology | Animals | Wnt Signaling Pathway - drug effects | Wnt Signaling Pathway - genetics | Cell Cycle Checkpoints - drug effects | Fluorescent Antibody Technique | Organoids - drug effects | Cell Line, Tumor | Mice | Care and treatment | Pancreatic cancer | Innovations | Development and progression | Genotype | Genetic engineering | Cellular signal transduction | Genetic aspects | Health aspects | Cell proliferation | Adenocarcinoma | Therapy | Wnt protein | Frizzled protein | Xenotransplantation | Colorectal carcinoma | Antibodies | Genomes | Cell surface | Genetic screening | Proteins | Receptors | Organoids | Xenografts | Inhibition | Pancreas | Recombinant | CRISPR | Immunoglobulins | Screens | Signaling | Mutation | Cancer | Tumors | Index Medicus
Journal Article