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Cukurova Medical Journal (Çukurova Üniversitesi Tıp Fakültesi Dergisi), ISSN 0250-5150, 03/2017, Volume 42, Issue 1, pp. 1 - 1
Journal Article
Cukurova Medical Journal, ISSN 2602-3032, 01/2017, Volume 42, Issue 1, pp. 1 - 12
Purpose: Bruton's tyrosine kinase (Btk) is known to be critical for B-lymphocyte development, proliferation and differentiation of B-cell lineages, convey... 
Tıp | Nrf2 and HO-1 | Nuclear Btk | Leukemia | Apoptosis
Journal Article
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 5759 - 5759
Resistance to the irreversible Bruton´s tyrosine kinase (BTK) inhibitors is the main cause of disease progression in patients with Chronic Lymphocytic Leukemia... 
Journal Article
The FEBS Journal, ISSN 1742-464X, 06/2011, Volume 278, Issue 12, p. 2001
The TEC family is ancient and constitutes the second largest family of cytoplasmic tyrosine kinases. In 1993, loss-of-function mutations in the BTK gene were... 
Proteins | Cellular biology | Genetics | Mutation | Kinases | Epidemiology
Journal Article
PLOS ONE, ISSN 1932-6203, 04/2017, Volume 12, Issue 4, p. e0174909
Bruton’s Tyrosine Kinase (BTK) is a cytoplasmic protein tyrosine kinase with a fundamental role in B-lymphocyte development and activation. The... 
Laboratories | Phages | Homology | Biochemistry | Biology | Kinases | Tissues | Western blotting | Proteins | Signal transduction | Cell activation | Libraries | Protein-tyrosine kinase | Tyrosine | Functional analysis | Src protein | Medical screening | Bruton's tyrosine kinase | Virology | Medicine | Screening | Lymphocytes B | Ligands | Ankyrin | Mutation | Binding sites
Journal Article
International Immunopharmacology, ISSN 1567-5769, 01/2020, Volume 78, p. 106042
Acute graft-versus-host disease (aGVHD) and kidney injury are the major complications after allogeneic hematopoietic stem cell transplantation (HSCT). Although... 
Tumor necrosis factor alpha | Fibroblast growth factor 23 | Lysosome | Acute graft versus host disease | αKlotho | Kidney injury | Hematopoietic stem cell transplantation | Interferon gamma
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2016, Volume 11, Issue 8, p. e0160255
Protein kinase B (AKT) phosphorylates numerous substrates on the consensus motif RXRXXpS/T, a docking site for 14-3-3 interactions. To identify novel... 
SURVIVAL | DOMAIN | PROTEIN-KINASE-B | AKT/PKB | PKB/AKT | PHOSPHORYLATION | PATHWAY | MULTIDISCIPLINARY SCIENCES | GROWTH | AKT | MECHANISMS | Phosphorylation | RNA Processing, Post-Transcriptional | Signal Transduction | TOR Serine-Threonine Kinases - metabolism | Humans | Cells, Cultured | Cercopithecus aethiops | Receptors, Antigen, B-Cell - metabolism | Mechanistic Target of Rapamycin Complex 2 | Receptors, Antigen, B-Cell - immunology | Mechanistic Target of Rapamycin Complex 1 | Multiprotein Complexes - metabolism | Animals | Mice | Oncogene Protein v-akt - metabolism | Proto-Oncogene Proteins c-akt - metabolism | COS Cells | Lymphocyte Activation - physiology | Proteins | Viral antibodies | RNA | Antibodies | Genetic transcription | Mass spectrometry | Protein kinases | Regulations | Transcription | Laboratories | Gene regulation | Science | Immunoblotting | AKT protein | Phylogeny | B-cell receptor | Kinases | Phosphatase | Signal transduction | Cell activation | Cell growth | Docking | RNA processing | Bioinformatics | Deoxyribonucleic acid--DNA | Binding | Splicing | Mass spectroscopy | Substrates | Zinc | Medicine | 14-3-3 protein | Hospitals | Inhibitors | Ribonucleic acids | Lymphocytes B | Proteomics | Receptor mechanisms | Regulatory proteins | Cancer | Biological Sciences | Biochemistry and Molecular Biology | Naturvetenskap | Natural Sciences | Biokemi och molekylärbiologi | Biologiska vetenskaper | Deoxyribonucleic acid | DNA
Journal Article
Journal Article
Journal Article
British Journal of Haematology, ISSN 0007-1048, 07/2016, Volume 174, Issue 1, pp. 117 - 126
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 09/2014, Volume 124, Issue 9, pp. 4067 - 4081
Journal Article
MOLECULAR AND CELLULAR BIOLOGY, ISSN 0270-7306, 08/2013, Volume 33, Issue 16, pp. 3214 - 3226
Bruton's tyrosine kinase (Btk) is crucial for B-lymphocyte activation and development. Mutations in the Btk gene cause X-linked agammaglobulinemia (XLA) in... 
FORKHEAD TRANSCRIPTION FACTOR | BRUTONS TYROSINE KINASE | PROTEIN | AKT/PKB | XID MICE | BIOCHEMISTRY & MOLECULAR BIOLOGY | X-LINKED AGAMMAGLOBULINEMIA | NUCLEAR EXPORT | KAPPA-B | SERINE PHOSPHORYLATION | CHRONIC MYELOID-LEUKEMIA | CELL BIOLOGY
Journal Article