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Fetal Diagnosis and Therapy, ISSN 1015-3837, 12/2014, Volume 36, Issue 4, pp. 282 - 286
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2011, Volume 108, Issue 43, pp. 17773 - 17778
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2009, Volume 106, Issue 8, pp. 2835 - 2840
The phosphatidylinositol 3-kinase subunit PIK3CA is frequently mutated in human cancers. Here we used gene targeting to "knock in" PIK3CA mutations into human... 
Cell growth | Phosphorylation | Epithelial cells | Chlorides | Cell lines | Colorectal cancer | Lead | Lithium | Genetic mutation | Heterologous transplantation | GSK3β | Phosphatidylinositol 3-kinase | MTOR | Cancer | CANCER-CELLS | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | GLYCOGEN-SYNTHASE KINASE-3-BETA | BREAST-CANCER | lithium | GENE | GROWTH | mTOR | HIGH-FREQUENCY | cancer | GSK3 beta | MUTATIONS | phosphatidylinositol 3-kinase | MAMMARY EPITHELIAL-CELLS | Protein Kinases - metabolism | Colorectal Neoplasms - genetics | Humans | Glycogen Synthase Kinase 3 beta | Transplantation, Heterologous | Extracellular Signal-Regulated MAP Kinases - metabolism | Mammary Glands, Human - metabolism | Breast Neoplasms - enzymology | Proto-Oncogene Proteins c-akt - metabolism | Oncogenes | Colorectal Neoplasms - enzymology | Glycogen Synthase Kinase 3 - metabolism | Gene Knock-In Techniques | Phosphatidylinositol 3-Kinases - genetics | Animals | Breast Neoplasms - genetics | Class I Phosphatidylinositol 3-Kinases | Breast Neoplasms - pathology | Mice, Nude | Cell Line, Tumor | Mice | TOR Serine-Threonine Kinases | Mutation | Colorectal Neoplasms - pathology | Phosphatidylinositol | Care and treatment | Gene mutations | Physiological aspects | Genetic aspects | Health aspects | Phosphotransferases | Risk factors | Biological Sciences
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 08/2010, Volume 120, Issue 8, pp. 2655 - 2658
Targeted cancer therapeutics can be effective when patients are preselected to maximize the chance of response. Increasingly, molecular markers such as... 
Journal Article
Nature Communications, ISSN 2041-1723, 2014, Volume 5, Issue 1, pp. 4961 - 4961
Journal Article
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 09/2015, Volume 112, Issue 37, pp. 11583 - 11588
Journal Article
PROTEOMICS, ISSN 1615-9853, 01/2015, Volume 15, Issue 2-3, pp. 318 - 326
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2015, Volume 112, Issue 37, pp. 11583 - 11588
The tumor protein 53 ( ) tumor suppressor gene is the most frequently somatically altered gene in human cancers. Here we show expression of ( ) is induced by... 
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2014, Volume 111, Issue 49, pp. 17606 - 17611
Tamoxifen is effective for treating estrogen receptor-alpha (ER) positive breast cancers. However, few molecular mediators of tamoxifen resistance have been... 
Tumor cell line | Cell growth | Estrogens | Cell lines | Genetic loci | Breast cancer | Gene expression regulation | Gene expression | Tumors | Cancer | Oncology, Experimental | Estrogen | Genetic research | Genetic aspects | Dosage and administration | Research | Tamoxifen | Drug resistance | Drug therapy
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 09/2015, Volume 112, Issue 37, p. 11583
  The tumor protein 53 (TP53) tumor suppressor gene is the most frequently somatically altered gene in human cancers. Here we show expression of N-Myc... 
Proteins | Cellular biology | Homeostasis | Genomes | Physiology | Gene expression | Tumors
Journal Article
Fetal Diagnosis and Therapy: clinical advances and basic research, ISSN 1015-3837, 12/2014, Volume 36, Issue 4, pp. 282 - 286
Objective: To develop a microarray-based method for noninvasive prenatal testing (NIPT) and compare it with next-generation sequencing. Methods: Maternal... 
Journal Article
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 09/2015, Volume 112, Issue 37, pp. 11583 - 11583
The tumor protein 53 (TP53) tumor suppressor gene is the most frequently somatically altered gene in human cancers. Here we show expression of N-Myc... 
Journal Article
Breast Cancer Research, ISSN 1465-5411, 02/2012, Volume 14, Issue 1, pp. R27 - R27
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2014, Volume 111, Issue 49, p. 17606
  Tamoxifen is effective for treating estrogen receptor-alpha (ER) positive breast cancers. However, few molecular mediators of tamoxifen resistance have been... 
Prescription drugs | Estrogen | Breast cancer | Metastasis | Gene expression | Drug resistance
Journal Article
Cancer Research, ISSN 0008-5472, 06/2013, Volume 73, Issue 11, pp. 3248 - 3261
Journal Article