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by Scott, IU and Oden, NL and VanVeldhuisen, PC and Ip, MS and Blodi, BA and Chan, CK and Bhargava, S and Figueroa, MJ and Musch, DC and Han, DP and Sadda, SR and Williams, GA and Wisniewski, S and Gaston, J and Figueroa, M and Bradley, L and De Stefano, J and Guan, E and Hoehn, A and Irazabal, A and Isman, S and King, J and Kondapaka, R and Kumar, H and Lahut, M and Lindblad, R and Lovett, R and Patschak, M and Rothwell, RS and Smith, R and Van Dyke, J and Watson, V and Yesko, L and Domalpally, A and Reed, S and Vargo, P and Reed, C and Abraham, P and Bement-Stump, B and Callahan, L and Dockter, M and Livermont, K and Nixon, R and Parks, D and Steinle, N and Thompson, A and Yu, DL and Bailey, S and Barth, J and Campbell, JP and Flaxel, C and Howell, C and Hui, J and Hwang, T and Ira, S and Lauer, A and Lin, P and Lundquist, A and Nolte, S and Pickell, S and Ryan, D and Schain, M and Steinkamp, P and Ukachukwu, C and Blefgen, S and Fujisaki, B and Liming, J and Mistretta, F and Petrolati, J and Berger, A and Darby, E and Dilts, V and Hamilton, R and Holm, L and McCarty, T and Medina, E and Misch, D and Moon, SJ and Owen, K and Randolph, J and Strickland, J and Sutherland, D and Tolentino, M and Varner, N and Balasubramaniam, U and Bojaj, S and Browning, D and Clark, L and Ennis, S and Fleming, C and Finch, A and Fredenberg, S and Gentile, A and Jackson, L and McClain, D and McOwen, M and Price, A and Punjabi, O and Rowland, B and Watson, L and ... and SCORE2 Investigator Grp and SCORE2 Investigator Group and for the SCORE2 Investigator Group
JAMA OPHTHALMOLOGY, ISSN 2168-6165, 12/2019, Volume 137, Issue 12, pp. 1389 - 1398
This secondary analysis of a randomized clinical trial investigates outcomes 1 year after cessation of the SCORE2 treatment schedule (24 months after... 
OPHTHALMOLOGY | RANIBIZUMAB | AFLIBERCEPT | Occlusion | Edema | Clinical trials | Retina | Vascular endothelial growth factor | Acuity | Bevacizumab
Journal Article
by Hutton, DW and Stein, JD and Glassman, AR and Bressler, NM and Jampol, LM and Sun, JK and Brown, JC and Antoszyk, AN and Browning, D and Price, AK and Fredenberg, SL and Herby, JT and Walker, MF and Fleming, CJ and McClain, AA and Karow, AS and Grupp, AC and Gallagher, KR and Ennis, SA and McClain, D and Mondello, JP and Finch, AK and Kimrey, K and Clark, LM and Jackson, LA and Watson, L and Kuopus, JA and Kerr, R and Bojaj, SJ and Held, SJ and Balasubramaniam, UM and McOwen, MD and Dunlap, M and Elman, MJ and Leder, HA and Starr, J and Belz, JL and Putzulo, CK and Salfer-Firestone, DY and Simpson, PM and Singletary, PV and Simmons, JL and Coffey, T and Sandler, DR and Davis, A and Metzger, AM and Sotirakos, P and Cain, T and Ketner, DJ and Friedman, SM and Moinfar, N and Williamson, KA and Sjoblom, K and Dawson, KL and Fagan, DF and Walters, PN and Carlton, S and McKinney, A and Baker, CW and Tilford, RH and Caldwell, TM and Lambert, LF and Orr, MJ and Palmer, MJ and Martin, TR and Camp, AB and Kettler, S and Williams, TR and Marcus, DM and Singh, H and Ortiz, SO and Acklie, TJ and Woodward, M and Roberts, CN and Floyd, GL and Hendrickson, J and Foster, LA and Coursey, C and Mims, V and Gardner, JC and Overton, KY and Ivey, K and Berger, BB and Jhaveri, CD and Moore, T and Gunderson, I and Walsh, RA and Manhart, GJ and Tracy, JJ and Riepen, D and Corak, B and Bravenec, CA and Nguyen, B and Reid, RM and Ren, Y and Stovall, CC and Ostrander, B and Pieramici, DJ and Castellarin, AA and Fishbein, S and ... and DRCR Retina Network and for the DRCR Retina Network
JAMA OPHTHALMOLOGY, ISSN 2168-6165, 12/2019, Volume 137, Issue 12, pp. 1424 - 1432
Importance The DRCR Retina Network Protocol S randomized clinical trial suggested that the mean visual acuity of eyes with proliferative diabetic retinopathy... 
OPHTHALMOLOGY | Edema | Diabetic retinopathy | Resource utilization | Retinopathy | Diabetes mellitus | Clinical trials | Retina | Patients | Acuity | Eye | Vision | Diabetes | Cost analysis | Vascular endothelial growth factor
Journal Article
by Bressler, NM and Odia, I and Maguire, M and Glassman, AR and Jampol, LM and MacCumber, MW and Shah, C and Rosberger, D and Sun, JK and Brown, JC and Antoszyk, AN and Browning, D and Price, AK and Fredenberg, SL and Herby, JT and Walker, MF and Fleming, CJ and McClain, AA and Karow, AS and Grupp, AC and Gallagher, KR and Ennis, SA and McClain, D and Mondelb, JP and Finch, AK and Kimrey, K and Clark, LM and Jackson, LA and Watson, L and Kuopus, JA and Kerr, R and Bojaj, SJ and Held, SJ and Balasubramaniam, UM and McOwen, MD and Dunlap, M and Elman, MJ and Leder, HA and Starr, J and Belz, JL and Putzulo, CK and Salfer-Firestone, DY and Simpson, PM and Singletary, PV and Simmons, JL and Coffey, T and Sandler, DR and Davis, A and Metzger, AM and Sotirakos, P and Cain, T and Ketner, DJ and Friedman, SM and Moinfar, N and Williamson, KA and Sjoblom, K and Dawson, KL and Fagan, DF and Walters, PN and Carlton, S and McKinney, A and Baker, CW and Tilford, RH and Caldwell, TM and Lambert, LF and Orr, MJ and Palmer, MJ and Martin, TR and Camp, AB and Kettler, S and Williams, TR and Marcus, DM and Singh, H and Ortiz, SO and Acklie, TJ and Woodward, M and Roberts, CN and Floyd, GL and Hendrickson, J and Foster, LA and Coursey, C and Mims, V and Gardner, JC and Overton, KY and Ivey, K and Berger, BB and Jhaveri, CD and Moore, T and Gunderson, I and Walsh, RA and Manhart, GJ and Tracy, JJ and Riepen, D and Corak, B and Bravenec, CA and Nguyen, B and Reid, RM and Ren, Y and Stovall, CC and Ostrander, B and ... and DRCR Retina Network and for the DRCR Retina Network
JAMA OPHTHALMOLOGY, ISSN 2168-6165, 09/2019, Volume 137, Issue 9, pp. 977 - 985
Key PointsQuestionWhat are the associations between changes in visual acuity and changes in optical coherence tomographic central subfield thickness across 3... 
OPHTHALMOLOGY | RETINOPATHY | OUTCOMES | OPTICAL COHERENCE TOMOGRAPHY | Edema | Diabetes mellitus | Clinical trials | Retina | Diabetes | Vascular endothelial growth factor | Patients | Acuity | Bevacizumab
Journal Article
by Jampol, Lee M and Glassman, Adam R and Liu, Danni and Aiello, Lloyd Paul and Bressler, Neil M and Duh, Elia J and Quaggin, Susan and Wells, John A and Wykoff, Charles C and Browning, David and Antoszyk, Andrew N and Price, Angela K and Fredenberg, Sherry L and Herby, Jenna T and Fleming, Christina J and McClain, Ashley A and Ennis, Sarah A and Gallagher, Kelly R and Karow, Angella S and Grupp, Autumn C and Puskas, Danielle and Watson, Lynn and Bojaj, Swann J and Balasubramaniam, Uma M and McClain, Donna and Styles, Donna R and Kuopus, Jeff A and Kimrey, Kathryn and Clark, Loraine M and Jackson, Lisa A and McOwen, Michael D and Dunlap, Matt and Held, Susannah J and Pieramici, Dante J and Nasir, Ma'an A and Castellarin, Alessandro A and Dhoot, Dilsher and Fishbein, Sarah and Giust, Jack and Wan, Lisha and Hanna, Michelle S and Rabena, Melvin D and Smith, Jerry and Bone, Layne J and Avery, Kelly and Giust, Matthew and Walker, Aimee and Shook, Aimee H and Esau, Sara and Ruvalcaba, Nitce L and Wells, John A and Clark, W. Lloyd and Johnson, David L and Payne, John F and Swinford, Tiffany R and Taylor, Mallie M and Garrison, Cassandra L and Miller, Peggy D and Houlahan, Amber R and O'Neill, Charlotte A and Floyd, Ashley and Parker, Crystal C and Sease, Courtney and Graham, Tara and Spencer, Robin and Ogbuewu, Tiffany N and Studebaker, Ashley and Huggins, Tyler and Spivey, Robbin and Jones, Brian and Williams, Ashley and Petty, Ron and Poston, Erin L and Ward, G. Michael and Baker, Carl W and Tilford, Ron H and Caldwell, Tracey M and Lambert, Lynnette F and Palmer, Mary J and Martin, Tracey R and Williams, Tana R and Kettler, Samantha and Camp, Alecia B and Silva, Paolo S and Arrigg, Paul G and Sharuk, George S and Shah, Sabera T and Sun, Jennifer K and Westerfeld, Corey and Andreoli, Christopher Michael and Aiello, Lloyd Paul and Schlossman, Deborah and Murtha, Timothy and Kwak, Hanna and Flores, Flor M and Stockman, Margaret E and Kieser, Troy and Krigman, Michael N and Bestourous, Leila and Weimann, Elizabeth S and ... and Diabetic Retinopathy Clinical Research Network and Diabet Retinopathy Clinical Res Ne
Ophthalmology, ISSN 0161-6420, 07/2018, Volume 125, Issue 7, pp. 1054 - 1063
To assess systemic vascular endothelial growth factor (VEGF)-A levels after treatment with intravitreous aflibercept, bevacizumab, or ranibizumab.... 
METAANALYSIS | PHARMACOKINETICS | BEVACIZUMAB | INJECTION | OPHTHALMOLOGY | RETINOPATHY | SERUM | RANIBIZUMAB | PREMATURITY | DEGENERATION
Journal Article
by Maturi, Raj K and Glassman, Adam R and Liu, Danni and Beck, Roy W and Bhavsar, Abdhish R and Bressler, Neil M and Jampol, Lee M and Melia, Michele and Punjabi, Omar S and Salehi-Had, Hani and Sun, Jennifer K and Browning, David and Antoszyk, Andrew N and Price, Angela K and Herby, Jenna T and Jones, Taylor S and Fredenberg, Sherry L and Mahr, Courtney and Fleming, Christina J and Ennis, Sarah A and Breglio, Erica and Karow, Angella S and Jackson, Lisa A and Balasubramaniam, Uma M and Bojaj, Swann J and McClain, Donna and Watson, Lynn and Clark, Loraine M and Kimrey, Kathryn and Kuopus, Jeff A and Simchik, Carol A and Rowland, Beverly O and Finch, Autumn K and McOwen, Michael D and Ahmed, Sara and Khodai, Amy L and Ramirez, Stephanie and Mireles, Michael J and Ma, Mary and Lee, Scott F and Rivero, Monica J and Castillo, Lily and Harless, Ashley M and Novak, Carolee K and Ellingwood, Nicole and White, Lorraine and Ware, Alisha and Weng, Christina Y and Coffee, Robert E and Carvounis, Petros Euthymiou and Blacutt, Wendy and Olfson, Margaret M and Schuetzle, Karri and Hemati, Pejman and Leger, April and Barnett, Dana B and Morales, Joseph F and Jones, Jacob M and Emerson, Geoffrey G and Dupont, Joan and Gilchrist, Andrea and Crannick, Dave A and Gaid, Gaid and Kinney, Erin C and Schoenecker, Hannah N and Evans, Alanna C and Gould, Nora and Scherer, Tonja and Vang, Denise and Ghuman, A. Thomas and Sharma, Ashish G and Raskauskas, Paul A and Knips, Eileen and Ryan, Cheryl and Kiesel, Cheryl and Peters, Crystal Y and Greenhoe, Laura and Torres, Natalie N and Leslie, Anita H and Dyshanowitz, Danielle and Kiesel, Raymond K and Bailey, Steven T and Flaxel, Christina J and Hwang, Thomas S and Lauer, Andreas K and Schain, Mitchell and Hanel, Shelley A and Lundquist, Ann D and Nolte, Susan K and Ira, Shirley D and Ryan, Dawn M and Pickell, Scott R and Steinkamp, Peter N and Barth, Jordan and Ukachukwu, Chiedozie and Hui, Jocelyn T and Howell, Chris S and Dhoot, Dilsher and Castellarin, Alessandro A and Pieramici, Dante J and ... and Diabet Retinopathy Clinical Res Ne and Diabetic Retinopathy Clinical Research Network and for the Diabetic Retinopathy Clinical Research Network
JAMA Ophthalmology, ISSN 2168-6165, 01/2018, Volume 136, Issue 1, pp. 29 - 38
IMPORTANCE Some eyes have persistent diabetic macular edema (DME) following anti-vascular endothelial growth factor (anti-VEGF) therapy for DME. Subsequently... 
OPHTHALMOLOGY | INTRAVITREAL IMPLANT | MONOTHERAPY | BEVACIZUMAB | 3-YEAR | LASER | Care and treatment | Dexamethasone | Analysis | Clinical trials | Eye diseases | Dosage and administration | Drug therapy | Online First | Original Investigation | Research
Journal Article
Journal Article
Epilepsia, ISSN 0013-9580, 01/2014, Volume 55, Issue 1, pp. 184 - 192
Summary Purpose The contribution of glial cells, mainly astrocytes and microglia, to the pathophysiology of epilepsy is increasingly appreciated. Glia play a... 
Astroglia | Cytokines | Inflammation | Connexin 43 | Glia | Antiepileptic drugs | Cellular viability | Microglia | SEIZURE SUSCEPTIBILITY | STATUS EPILEPTICUS | CEREBROSPINAL-FLUID | CLINICAL NEUROLOGY | IN-VITRO | GAP-JUNCTIONS | TUBEROUS SCLEROSIS COMPLEX | BRAIN INFLAMMATION | CULTURED ASTROCYTES | RAT HIPPOCAMPUS | TNF-ALPHA | Gabapentin | Rats, Wistar | Coculture Techniques | Epilepsy - physiopathology | Anticonvulsants - pharmacology | Epilepsy - etiology | Valproic Acid - pharmacology | Neuroglia - drug effects | Dose-Response Relationship, Drug | Microglia - physiology | Inflammation - drug therapy | Amines - therapeutic use | Phenytoin - pharmacology | Valproic Acid - therapeutic use | gamma-Aminobutyric Acid - therapeutic use | Transforming Growth Factor beta1 - biosynthesis | Astrocytes - drug effects | Carbamazepine - pharmacology | Cyclohexanecarboxylic Acids - therapeutic use | Enzyme-Linked Immunosorbent Assay | Microglia - drug effects | Cells, Cultured | Neuroglia - physiology | Anticonvulsants - therapeutic use | Carbamazepine - therapeutic use | Connexin 43 - biosynthesis | Rats | gamma-Aminobutyric Acid - pharmacology | Blotting, Western | Astrocytes - physiology | Animals | Gap Junctions - physiology | Phenytoin - therapeutic use | Cyclohexanecarboxylic Acids - pharmacology | Epilepsy - drug therapy | Gap Junctions - drug effects | Amines - pharmacology | Inflammation - physiopathology | Drugs | Enzymes | Divalproex | Analysis | Epilepsy | Bone morphogenetic proteins | Cytochemistry | Valproic acid | Drug therapy | Transforming growth factors | Tumor necrosis factor-TNF | Drug dosages | Rodents | Antiepileptic agents
Journal Article