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The New England Journal of Medicine, ISSN 0028-4793, 11/2018, Volume 379, Issue 22, pp. 2108 - 2121
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 1118 - 1118
Abstract Introduction: Intrinsic apoptosis is regulated by the BCL-2 family of proteins, which consists of both anti-apoptotic (BCL-2, BCL-XL, MCL-1) and... 
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2012, Volume 109, Issue 45, pp. 18529 - 18534
Journal Article
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 2616 - 2616
Journal Article
Journal of Neuro-Oncology, ISSN 0167-594X, 11/2018, Volume 140, Issue 2, pp. 317 - 328
Glioblastoma is the most common primary malignant brain tumor. No standard treatment exists for recurrent disease. Glioblastoma is associated with an... 
Neurology | Medicine & Public Health | Tumor mutational burden (TMB) | Glioblastoma (GBM) | Oncology | Programmed death-ligand 1 (PD-L1) | Atezolizumab | EFFICACY | BEVACIZUMAB | PD-1 BLOCKADE | DEATH-LIGAND 1 | ISOCITRATE DEHYDROGENASE MUTATIONS | CLINICAL NEUROLOGY | TEMOZOLOMIDE | TUMOR-INFILTRATING LYMPHOCYTES | ONCOLOGY | RANDOMIZED PHASE-III | GRADE GLIOMAS | EXPRESSION | Bevacizumab - therapeutic use | Follow-Up Studies | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Neoplasm Recurrence, Local - drug therapy | Antibodies, Monoclonal - therapeutic use | Lipids | Male | Antineoplastic Agents - therapeutic use | Neoplasm Recurrence, Local - mortality | Brain Neoplasms - metabolism | Glioblastoma - genetics | Antineoplastic Agents - adverse effects | Biomarkers, Tumor - metabolism | Adult | Female | Glioblastoma - metabolism | Brain Neoplasms - mortality | DNA Polymerase II - genetics | Neoplasm Recurrence, Local - metabolism | Brain Neoplasms - genetics | Poly-ADP-Ribose Binding Proteins - genetics | Isocitrate Dehydrogenase - genetics | Treatment Outcome | Brain Neoplasms - drug therapy | Administration, Intravenous | Neoplasm Recurrence, Local - genetics | Aged | Glioblastoma - drug therapy | Glioblastoma - mortality | Care and treatment | Chemotherapy | Relapse | Safety and security measures | Brain tumors | T cells | Glioblastoma multiforme | Diseases | Cancer | Toxicity | Brain cancer | Glioblastoma | Lymphocytes T | Patients | Bevacizumab | CD4 antigen | Immunosuppression | Immune checkpoint | Biomarkers | Safety | Apoptosis
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 09/2017, Volume 23, Issue 17, pp. 5238 - 5245
Journal Article
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 5707 - 5707
Journal Article
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 04/2008, Volume 28, Issue 7, pp. 2470 - 2480
Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
TCR | PHOSPHORYLATION | KINASE-C-THETA | CARMA1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | CD28 | IMMUNOLOGICAL SYNAPSE | LYMPHOCYTE-ACTIVATION | PKC-THETA | CUTTING EDGE | CELL BIOLOGY
Journal Article
Journal of Immunology, ISSN 0022-1767, 04/2011, Volume 186, Issue 8, pp. 4609 - 4617
Journal Article
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. CT028 - CT028
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2016, Volume 11, Issue 11, p. e0165856
Journal Article
Journal of Immunology, ISSN 0022-1767, 04/2016, Volume 196, Issue 7, pp. 2933 - 2938
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2017, Volume 35, Issue 15_suppl, pp. 5585 - 5585
Journal Article
Science Translational Medicine, ISSN 1946-6234, 02/2014, Volume 6, Issue 225, p. 225ra28
The density and type of lymphocytes that infiltrate colon tumors are predictive of the clinical outcome of colon cancer. High densities of T helper 17 (T(H)17)... 
SURVIVAL | MEDICINE, RESEARCH & EXPERIMENTAL | ROR-GAMMA-T | GENE | COLORECTAL-CANCER | INFLAMMATION | POLYPOSIS | MAST-CELLS | INTERLEUKIN-10 | SPECIFICATION | TH17 CELLS | CELL BIOLOGY | T-Lymphocytes, Regulatory - metabolism | Colonic Neoplasms - genetics | Colitis - genetics | Humans | Gene Expression Regulation, Neoplastic | Colitis - pathology | Colon - immunology | Colonic Neoplasms - metabolism | DNA-Binding Proteins - deficiency | Genes, APC | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | Th17 Cells - metabolism | Cell Transformation, Neoplastic - genetics | Colonic Neoplasms - immunology | Nuclear Receptor Subfamily 1, Group F, Member 3 - metabolism | Inflammation Mediators - metabolism | Lymphocytes, Tumor-Infiltrating - metabolism | Colitis - immunology | T Cell Transcription Factor 1 - metabolism | Binding Sites | Nuclear Receptor Subfamily 1, Group F, Member 3 - genetics | Wnt Signaling Pathway | Disease Models, Animal | Colon - pathology | Lymphocyte Activation | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Hepatocyte Nuclear Factor 1-alpha | Chromatin Assembly and Disassembly | Mice, Transgenic | DNA-Binding Proteins - genetics | Cell Transformation, Neoplastic - metabolism | beta Catenin - metabolism | Colon - metabolism | beta Catenin - genetics | T Cell Transcription Factor 1 - genetics | Cell Transformation, Neoplastic - immunology | Animals | Colonic Neoplasms - pathology | Colitis - metabolism | Cell Line, Tumor | Th17 Cells - immunology | Mice | Lymphocytes, Tumor-Infiltrating - immunology
Journal Article
Clinical cancer research : an official journal of the American Association for Cancer Research, ISSN 1078-0432, 07/2019, Volume 25, Issue 20, pp. 6061 - 6072
Atezolizumab (anti-programmed death-ligand 1 [PD-L1]) selectively targets PD-L1 to block its interaction with receptors programmed death 1 and B7.1, thereby... 
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 02/2019, Volume 105, Issue 2, pp. 486 - 495
To assess circulating biomarkers as predictors of antitumor response to atezolizumab (anti‐programmed death‐ligand 1 (PD‐L1), Tecentriq) serum pharmacokinetic... 
SURVIVAL | COMBINATIONS | GROWTH KINETICS | PEMBROLIZUMAB | ONCOLOGY | IMMUNOTHERAPY | END-POINTS | PHARMACOLOGY & PHARMACY | OPEN-LABEL | BLOCKADE | IPILIMUMAB | Research
Journal Article
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