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by Thygesen, Kristian and Alpert, Joseph S and Jaffe, Allan S and Simoons, Maarten L and Chaitman, Bernard R and White, Harvey D and Katus, Hugo A and Apple, Fred S and Lindahl, Bertil and Morrow, David A and Clemmensen, Peter M and Johanson, Per and Hod, Hanoch and Underwood, Richard and Bax, Jeroen J and Bonow, Robert O and Pinto, Fausto and Gibbons, Raymond J and Fox, Keith A and Atar, Dan and Newby, L. Kristin and Galvani, Marcello and Hamm, Christian W and Uretsky, Barry F and Gabriel Steg, Ph and Wijns, William and Bassand, Jean-Pierre and Menasché, Phillippe and Ravkilde, Jan and Ohman, E. Magnus and Antman, Elliott M and Wallentin, Lars C and Armstrong, Paul W and Januzzi, James L and Nieminen, Markku S and Gheorghiade, Mihai and Filippatos, Gerasimos and Luepker, Russell V and Fortmann, Stephen P and Rosamond, Wayne D and Levy, Dan and Wood, David and Smith, Sidney C and Hu, Dayi and Lopez-Sendon, José-Luis and Robertson, Rose Marie and Weaver, Douglas and Tendera, Michal and Bove, Alfred A and Parkhomenko, Alexander N and Vasilieva, Elena J and Mendis, Shanti and Baumgartner, Helmut and Ceconi, Claudio and Dean, Veronica and Deaton, Christi and Fagard, Robert and Funck-Brentano, Christian and Hasdai, David and Hoes, Arno and Kirchhof, Paulus and Knuuti, Juhani and Kolh, Philippe and McDonagh, Theresa and Moulin, Cyril and Popescu, Bogdan A and Reiner, Željko and Sechtem, Udo and Sirnes, Per Anton and Torbicki, Adam and Vahanian, Alec and Windecker, Stephan and Morais, Joao and Aguiar, Carlos and Almahmeed, Wael and Arnar, David O and Barili, Fabio and Bloch, Kenneth D and Bolger, Ann F and Bøtker, Hans Erik and Bozkurt, Biykem and Bugiardini, Raffaele and Cannon, Christopher and de Lemos, James and Eberli, Franz R and Escobar, Edgardo and Hlatky, Mark and James, Stefan and Kern, Karl B and Moliterno, David J and Mueller, Christian and Neskovic, Aleksandar N and Pieske, Burkert Mathias and Schulman, Steven P and Storey, Robert F and Taubert, Kathryn A and Vranckx, Pascal and Wagner, Daniel R and Classification Subcommittee and Heart Failure Subcommittee and Authors/Task Force Members Chairpersons and ECG Subcommittee and Imaging Subcommittee and Trials & Registries Subcommittee and Biomarker Subcommittee and Intervention Subcommittee and Global Perspective Subcommittee and ESC Committee for Practice Guidelines (CPG) and the Writing Group on behalf of the Joint ESC/ACCF/AHA/WHF Task Force for the Universal Definition of Myocardial Infarction and Epidemiology Subcommittee and Document Reviewers and Joint ESC ACCF AHA WHF Task Force and Writing Group on the Joint ESC/ACCF/AHA/WHF Task Force for the Universal Definition of Myocardial Infarction
European heart journal, ISSN 1522-9645, 10/2012, Volume 33, Issue 20, pp. 2551 - 2567
Journal Article
The New England journal of medicine, ISSN 1533-4406, 01/2012, Volume 366, Issue 1, pp. 20 - 33
In this trial, vorapaxar, a protease-activated–receptor 1 antagonist that inhibits thrombin-induced platelet activation, was not effective in reducing the... 
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Follow-Up Studies | Angioplasty | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Male | Pyridines - adverse effects | Cardiovascular Diseases - mortality | Female | Drug Therapy, Combination | Platelet Aggregation Inhibitors - therapeutic use | Platelet Aggregation Inhibitors - adverse effects | Pyridines - therapeutic use | Double-Blind Method | Receptor, PAR-1 - antagonists & inhibitors | Kaplan-Meier Estimate | Combined Modality Therapy | Lactones - adverse effects | Lactones - therapeutic use | Acute Coronary Syndrome - drug therapy | Intracranial Hemorrhages - chemically induced | Coronary Artery Bypass | Acute Coronary Syndrome - therapy | Aged | Hemorrhage - chemically induced | Antagonists (Biochemistry) | Drugs | Dose-response relationship (Biochemistry) | Dosage and administration | Product/Service Evaluations | Drug therapy | Coronary heart disease | Myocardial infarction | Cerebral infarction | Stroke | Heart attacks | Proteinase-activated receptor 1 | Thrombin | Cardiovascular disease | Hemorrhage | Bleeding | Investigations | Manuscripts | Ischemia | Blood platelets | Acute coronary syndromes | Research centers | Index Medicus | Abridged Index Medicus | Malalties cardiovasculars | Bypass cardiopulmonar | Medicaments | Bypass cardiopulmonary | Plaquetes sanguínies | Cardiovascular diseases
Journal Article
The Lancet (British edition), ISSN 0140-6736, 11/2013, Volume 382, Issue 9906, pp. 1714 - 1722
Journal Article
The New England journal of medicine, ISSN 1533-4406, 04/2012, Volume 366, Issue 15, pp. 1404 - 1413
Patients with atherosclerotic vascular disease were randomly assigned to receive the thrombin antagonist vorapaxar or placebo. Vorapaxar reduced the rate of... 
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Male | Risk | Secondary Prevention | Pyridines - adverse effects | Cardiovascular Diseases - mortality | Female | Platelet Aggregation Inhibitors - therapeutic use | Platelet Aggregation Inhibitors - adverse effects | Pyridines - therapeutic use | Double-Blind Method | Hemorrhage - epidemiology | Receptor, PAR-1 - antagonists & inhibitors | Kaplan-Meier Estimate | Peripheral Arterial Disease - drug therapy | Stroke - drug therapy | Lactones - adverse effects | Lactones - therapeutic use | Retreatment | Myocardial Infarction - drug therapy | Brain Ischemia - drug therapy | Intracranial Hemorrhages - chemically induced | Intracranial Hemorrhages - epidemiology | Aged | Hemorrhage - chemically induced | Prevention | Drugs | Aggregation | Dose-response relationship (Biochemistry) | Atheroembolism | Blood platelets | Atherosclerosis | Product/Service Evaluations | Dosage and administration | Drug therapy | Myocardial infarction | Cerebral infarction | Stroke | Aspirin | Heart attacks | Proteinase-activated receptor 1 | Thrombin | Hemorrhage | Patients | Bleeding | Disease prevention | Ischemia | Arteriosclerosis | Death | Cardiovascular diseases | Health risk assessment | Index Medicus | Abridged Index Medicus | Computer Science | Medical Imaging
Journal Article