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Das Historisch-Politische Buch, ISSN 0018-2605, 06/2019, Volume 67, Issue 2, pp. 258 - 259
Journal Article
2013, Methods in Molecular Biology, Methods and Protocols, ISBN 9781627033107, Volume 986
The major reason for the elevated costs of drug development in the pharmaceutical industry is the high attrition rate. In Target Identification and Validation... 
Medicine | Toxicology | Biochemistry
Web Resource
Zeitschrift der Savigny-Stiftung für Rechtsgeschichte: Germanistische Abteilung, ISSN 0323-4045, 08/2010, Volume 127, Issue 1, pp. 914 - 916
Journal Article
Current Drug Targets, ISSN 1389-4501, 10/2010, Volume 11, Issue 10, pp. 1325 - 1335
Aneuploidy is one of the major hallmarks of cancer cells and several paths towards aneuploidy have been described. However, the relevance for tumor initiation... 
Molecular modelling | Mitosis | Cell cycle | Aneuploidy | Drug development | Stress | Cancer | Tumors
Journal Article
Magnetic Resonance in Medicine, ISSN 0740-3194, 06/2017, Volume 77, Issue 6, pp. 2097 - 2106
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 06/2008, Volume 4, Issue 6, pp. 357 - 365
Cdc7 is an essential kinase that promotes DNA replication by activating origins of replication. Here, we characterized the potent Cdc7 inhibitor PHA-767491 (1)... 
YEAST | IN-VITRO PHOSPHORYLATION | APOPTOSIS | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | HUMAN CDC7-RELATED KINASE | S-PHASE | AGENTS | HUMAN CANCER-CELLS | HUMAN HOMOLOG | CYCLE | Phosphorylation | DNA Replication - drug effects | Humans | Structure-Activity Relationship | Minichromosome Maintenance Complex Component 2 | Cell Cycle Proteins - antagonists & inhibitors | Cell Cycle Proteins - chemistry | Dose-Response Relationship, Drug | Protein Kinase Inhibitors - chemistry | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Cell Cycle Proteins - genetics | DNA - biosynthesis | Antineoplastic Agents - pharmacology | Molecular Structure | Cell Death - drug effects | DNA - drug effects | Protein-Serine-Threonine Kinases - genetics | Rats | Antineoplastic Agents - chemistry | Mice, SCID | Nuclear Proteins - chemistry | Piperidones - pharmacology | Xenograft Model Antitumor Assays | Piperidones - chemistry | Pyrroles - pharmacology | Animals | Mice, Nude | Small Molecule Libraries | Fibroblasts - drug effects | Nuclear Proteins - antagonists & inhibitors | Cell Line, Tumor | Pyrroles - chemistry | Cell Proliferation - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Protein-Serine-Threonine Kinases - chemistry | HeLa Cells | Cell Cycle - drug effects | Biochemistry | Inhibitor drugs | Kinases | DNA damage | Cancer
Journal Article
BMC Musculoskeletal Disorders, ISSN 1471-2474, 01/2018, Volume 19, Issue 1, pp. 9 - 7
Background: Chondrosarcoma is the second most common primary malignant bone tumor. Because of their heterogeneity, with differences in invasive and metastatic... 
MMP | Chondrosarcoma | Matrix metalloproteinases | Prognosis | Metastasis | Grading | SURVIVAL | INTEGRIN | LYMPH-NODES | TISSUE INHIBITORS | RHEUMATOLOGY | CELL CARCINOMA | BREAST-CANCER | MATRIX-METALLOPROTEINASE-9 | OSTEOSARCOMA | PROGNOSTIC-SIGNIFICANCE | ORTHOPEDICS | Genetic aspects | Research | Gene expression
Journal Article
Circulation, ISSN 0009-7322, 06/2013, Volume 127, Issue 23, pp. 2264 - 2271
Journal Article
Journal Article
Journal of Child Psychology and Psychiatry, ISSN 0021-9630, 01/2013, Volume 54, Issue 6, pp. 686 - 694
Journal Article
Neoplasia, ISSN 1476-5586, 09/2009, Volume 11, Issue 9, pp. 934 - 944
Journal Article
Current Drug Targets, ISSN 1389-4501, 2010, Volume 11, Issue 10, pp. 1325 - 1335
Journal Article
Clinical Neurophysiology, ISSN 1388-2457, 03/2018, Volume 129, Issue 3, pp. 526 - 540
In consistent orthographies, isolated reading disorders (iRD) and isolated spelling disorders (iSD) are nearly as common as combined reading-spelling disorders... 
Word processing | Dyslexia | Phonological lexical decision task | ERP | Reading disorder | Spelling disorder | READERS | CONFLICT | N400 | RECOGNITION | REGULAR ORTHOGRAPHIES | TIME-COURSE | POTENTIALS | NEUROSCIENCES | CLINICAL NEUROLOGY | DEVELOPMENTAL DYSLEXIA | SPECIALIZATION | Medicine, Experimental | Medical research | Neurophysiology
Journal Article