Molecular Nutrition & Food Research, ISSN 1613-4125, 05/2019, Volume 63, Issue 9, pp. e1801239 - n/a
Scope Dietary polyphenols may protect against breast cancer. However, it is unknown whether polyphenols reach human malignant breast tumors in molecular forms...
polyphenols | breast cancer | methylxanthine | clinical trials | tissue disposition | ASSAY | FOOD SCIENCE & TECHNOLOGY | CAFFEINE | PREVENTION | RISK | RECEPTOR | CELL-PROLIFERATION | WOMEN | FRUIT | UROLITHINS | CONSUMPTION | Prevention | Care and treatment | Cancer patients | Metabolites | Resveratrol | Polyphenols | Breast cancer | Sulfates | Cancer | Caffeine | Profiling | Tissues | Cocoa | Anticancer properties | Xenoestrogens | Surgery | Urine | Citrus fruits | Metabolism | Phenolic compounds | Dihydroxybenzoic acid | Lemons | Chemotherapy | Diet | Biopsy | Phenols | Breast | Antitumor activity | Conjugation | Sulfate | Tumors
polyphenols | breast cancer | methylxanthine | clinical trials | tissue disposition | ASSAY | FOOD SCIENCE & TECHNOLOGY | CAFFEINE | PREVENTION | RISK | RECEPTOR | CELL-PROLIFERATION | WOMEN | FRUIT | UROLITHINS | CONSUMPTION | Prevention | Care and treatment | Cancer patients | Metabolites | Resveratrol | Polyphenols | Breast cancer | Sulfates | Cancer | Caffeine | Profiling | Tissues | Cocoa | Anticancer properties | Xenoestrogens | Surgery | Urine | Citrus fruits | Metabolism | Phenolic compounds | Dihydroxybenzoic acid | Lemons | Chemotherapy | Diet | Biopsy | Phenols | Breast | Antitumor activity | Conjugation | Sulfate | Tumors
Journal Article
Molecular Nutrition & Food Research, ISSN 1613-4125, 06/2014, Volume 58, Issue 6, pp. 1199 - 1211
Scope Urolithins are bioactive metabolites produced by the gut microbiota from ellagitannins (ETs) and ellagic acid (EA). We investigated whether urolithins...
Clinical trial | Colon cancer | Urolithins | Pomegranate | Ellagic acid | RESVERATROL | OXIDATIVE STRESS | FRUIT EXTRACT | FOOD SCIENCE & TECHNOLOGY | ELLAGITANNINS | IN-VITRO | ANTIOXIDANT | INFLAMMATION | JUICE | ACID-DERIVED METABOLITES | Coumarins - metabolism | Ellagic Acid - metabolism | Plant Extracts - pharmacology | Humans | Middle Aged | Colon - drug effects | Polyphenols - pharmacology | Male | Tandem Mass Spectrometry | Aged, 80 and over | Chromatography, Liquid | Adult | Female | Colorectal Neoplasms - metabolism | Body Mass Index | Punicaceae - chemistry | Limit of Detection | Reproducibility of Results | Coumarins - urine | Metabolomics - methods | Colon - metabolism | Coumarins - blood | Hydrolyzable Tannins - urine | Aged | Hydrolyzable Tannins - blood | Cancer patients | Care and treatment | Metabolites | Microbiota (Symbiotic organisms) | Colorectal cancer | Polyphenols | Liquid chromatography
Clinical trial | Colon cancer | Urolithins | Pomegranate | Ellagic acid | RESVERATROL | OXIDATIVE STRESS | FRUIT EXTRACT | FOOD SCIENCE & TECHNOLOGY | ELLAGITANNINS | IN-VITRO | ANTIOXIDANT | INFLAMMATION | JUICE | ACID-DERIVED METABOLITES | Coumarins - metabolism | Ellagic Acid - metabolism | Plant Extracts - pharmacology | Humans | Middle Aged | Colon - drug effects | Polyphenols - pharmacology | Male | Tandem Mass Spectrometry | Aged, 80 and over | Chromatography, Liquid | Adult | Female | Colorectal Neoplasms - metabolism | Body Mass Index | Punicaceae - chemistry | Limit of Detection | Reproducibility of Results | Coumarins - urine | Metabolomics - methods | Colon - metabolism | Coumarins - blood | Hydrolyzable Tannins - urine | Aged | Hydrolyzable Tannins - blood | Cancer patients | Care and treatment | Metabolites | Microbiota (Symbiotic organisms) | Colorectal cancer | Polyphenols | Liquid chromatography
Journal Article
Molecular Nutrition & Food Research, ISSN 1613-4125, 10/2015, Volume 59, Issue 10, pp. 1973 - 1986
Scope MicroRNAs (miRs) are proposed as colorectal cancer (CRC) biomarkers. Pomegranate ellagic acid and their microbiota metabolites urolithins exert...
Clinical trials | microRNA | Colon cancer | Urolithins | Pomegranate | MicroRNA | MORTALITY | RESVERATROL | FOOD SCIENCE & TECHNOLOGY | PROLIFERATION | COMBINATION | CELL CARCINOMA | RECTAL-CANCER | POLYPHENOLS | PROFILE | METABOLISM | MIRNA | Colorectal Neoplasms - surgery | Colon - physiology | Double-Blind Method | Plant Extracts - pharmacology | Colorectal Neoplasms - genetics | Humans | Middle Aged | Colon - drug effects | Male | Preoperative Care | Aged, 80 and over | Female | Aged | Biomarkers, Tumor - genetics | Colorectal Neoplasms - diet therapy | MicroRNAs - genetics | Punicaceae | Gene Expression Regulation, Neoplastic - drug effects | Colorectal Neoplasms - pathology | Metabolites | Microbiota (Symbiotic organisms) | Analysis | Colonoscopy | Colorectal cancer | Biological markers
Clinical trials | microRNA | Colon cancer | Urolithins | Pomegranate | MicroRNA | MORTALITY | RESVERATROL | FOOD SCIENCE & TECHNOLOGY | PROLIFERATION | COMBINATION | CELL CARCINOMA | RECTAL-CANCER | POLYPHENOLS | PROFILE | METABOLISM | MIRNA | Colorectal Neoplasms - surgery | Colon - physiology | Double-Blind Method | Plant Extracts - pharmacology | Colorectal Neoplasms - genetics | Humans | Middle Aged | Colon - drug effects | Male | Preoperative Care | Aged, 80 and over | Female | Aged | Biomarkers, Tumor - genetics | Colorectal Neoplasms - diet therapy | MicroRNAs - genetics | Punicaceae | Gene Expression Regulation, Neoplastic - drug effects | Colorectal Neoplasms - pathology | Metabolites | Microbiota (Symbiotic organisms) | Analysis | Colonoscopy | Colorectal cancer | Biological markers
Journal Article
The Journal of Nutritional Biochemistry, ISSN 0955-2863, 04/2017, Volume 42, pp. 126 - 133
The clinical evidence of dietary polyphenols as colorectal cancer (CRC) chemopreventive compounds is very weak. Verification in humans of tissue-specific...
Colon tissues | Ellagitannins | Urolithins | Interindividual variability | Pomegranate extract | Clinical trial | Gene expression | RNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | MODEL | IDENTIFICATION | ELLAGIC ACID METABOLISM | BIOMARKERS | POLYPHENOLS | NUTRITION & DIETETICS | BETA-CAROTENE SUPPLEMENTATION | NORMALIZATION | PCR | Punicaceae - chemistry | Plant Extracts - chemistry | Reproducibility of Results | Plant Extracts - pharmacology | Colorectal Neoplasms - genetics | Humans | Gene Expression Regulation, Neoplastic | Male | Aged, 80 and over | Hydrolyzable Tannins - pharmacology | Female | Aged | Colorectal Neoplasms - diet therapy | Ellagic acid | Genes | Colorectal cancer | Genetic research | Clinical trials | Polyphenols | Genetic aspects | Cancer | Tumor proteins
Colon tissues | Ellagitannins | Urolithins | Interindividual variability | Pomegranate extract | Clinical trial | Gene expression | RNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | MODEL | IDENTIFICATION | ELLAGIC ACID METABOLISM | BIOMARKERS | POLYPHENOLS | NUTRITION & DIETETICS | BETA-CAROTENE SUPPLEMENTATION | NORMALIZATION | PCR | Punicaceae - chemistry | Plant Extracts - chemistry | Reproducibility of Results | Plant Extracts - pharmacology | Colorectal Neoplasms - genetics | Humans | Gene Expression Regulation, Neoplastic | Male | Aged, 80 and over | Hydrolyzable Tannins - pharmacology | Female | Aged | Colorectal Neoplasms - diet therapy | Ellagic acid | Genes | Colorectal cancer | Genetic research | Clinical trials | Polyphenols | Genetic aspects | Cancer | Tumor proteins
Journal Article
Food Research International, ISSN 0963-9969, 08/2013, Volume 53, Issue 1, pp. 403 - 408
Glucosinolates are sulphur-containing compounds present in species that are hydrolyzed by the plant enzyme myrosinase to isothiocyanates (ITC), which have...
Cooking | Myrosinase | Isothiocyanates | Sulforaphane | Brassica oleracea Italica Group × Alboglabra Group | Brassica oleracea Italica Group×Alboglabra Group | Group | FOOD SCIENCE & TECHNOLOGY | PREVENTION | EXCRETION | CRUCIFEROUS VEGETABLES | QUANTITATIVE-DETERMINATION | INGESTION | WATERCRESS | URINE | ARABIDOPSIS | Brassica oleracea Italica Group x Alboglabra | Broccoli | Brassica | Vegetables | Statistical analysis | Samples | Raw | Statistical methods | Ingestion
Cooking | Myrosinase | Isothiocyanates | Sulforaphane | Brassica oleracea Italica Group × Alboglabra Group | Brassica oleracea Italica Group×Alboglabra Group | Group | FOOD SCIENCE & TECHNOLOGY | PREVENTION | EXCRETION | CRUCIFEROUS VEGETABLES | QUANTITATIVE-DETERMINATION | INGESTION | WATERCRESS | URINE | ARABIDOPSIS | Brassica oleracea Italica Group x Alboglabra | Broccoli | Brassica | Vegetables | Statistical analysis | Samples | Raw | Statistical methods | Ingestion
Journal Article
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