2000, ISBN 9780415217125, xii, 265
Can moral disagreements be rationally resolved? Can universal human rights be defended in face of moral disagreements? The problem of moral disagreement is one...
Ethical problems | Philosophy | Ethics Philosophy | Ethics
Ethical problems | Philosophy | Ethics Philosophy | Ethics
Book
2015, ISBN 0820348155, xiii, 252
Book
1998, Contributions in philosophy, ISBN 0313305277, Volume no. 64, viii, 252
Book
The Lancet, ISSN 0140-6736, 05/2018, Volume 391, Issue 10135, pp. 2106 - 2106
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2013, Volume 62, Issue 16, pp. 1466 - 1473
Objectives This study sought to provide bedside evidence of the potential link between cardiac mitochondrial dysfunction and arrhythmia as reported in bench...
Cardiovascular | Internal Medicine | cardiac surgery | atrial fibrillation | diabetes | mitochondria | gene expression | CARDIAC & CARDIOVASCULAR SYSTEMS | METABOLISM | CHANNEL | DIABETIC HUMAN HEART | CARDIAC-SURGERY | ATRIAL-FIBRILLATION | Sects | Diabetes | Hypertension | Heart | Cardiac arrhythmia | Phosphorylation | Mortality | Cardiomyocytes | Permeability | Kinases | Retention | Studies | Heart rate | Mitochondria | Lipoproteins | Biopsy | Surgery | Blood pressure | Cardiology | Potassium
Cardiovascular | Internal Medicine | cardiac surgery | atrial fibrillation | diabetes | mitochondria | gene expression | CARDIAC & CARDIOVASCULAR SYSTEMS | METABOLISM | CHANNEL | DIABETIC HUMAN HEART | CARDIAC-SURGERY | ATRIAL-FIBRILLATION | Sects | Diabetes | Hypertension | Heart | Cardiac arrhythmia | Phosphorylation | Mortality | Cardiomyocytes | Permeability | Kinases | Retention | Studies | Heart rate | Mitochondria | Lipoproteins | Biopsy | Surgery | Blood pressure | Cardiology | Potassium
Journal Article
Circulation Research, ISSN 0009-7330, 08/2018, Volume 123, Issue 6, pp. 648 - 650
Although compelling evidence has demonstrated that the circadian rhythm exerts major effects on virtually all cardiovascular (patho) physiological processes,...
TRIAL | CARDIAC & CARDIOVASCULAR SYSTEMS | circadian rhythm | myocardial infarction | cardioprotection | cardiac surgery | chronotherapy | PERIPHERAL VASCULAR DISEASE | reperfusion injury | HEMATOLOGY
TRIAL | CARDIAC & CARDIOVASCULAR SYSTEMS | circadian rhythm | myocardial infarction | cardioprotection | cardiac surgery | chronotherapy | PERIPHERAL VASCULAR DISEASE | reperfusion injury | HEMATOLOGY
Journal Article
The Lancet, ISSN 0140-6736, 01/2018, Volume 391, Issue 10115, pp. 59 - 69
On-pump cardiac surgery provokes a predictable perioperative myocardial ischaemia–reperfusion injury which is associated with poor clinical outcomes. We...
INFARCT SIZE | CLOCK GENES | HEART | MEDICINE, GENERAL & INTERNAL | CELLULAR BIOLOGY | ELEVATION | TIME | POSITION PAPER | EXPRESSION | CIRCADIAN DEPENDENCE | Signal Transduction | Humans | Middle Aged | Postoperative Complications - metabolism | Male | Treatment Outcome | Myocardial Reperfusion Injury - epidemiology | Postoperative Complications - epidemiology | Circadian Rhythm | Case-Control Studies | Nuclear Receptor Subfamily 1, Group D, Member 1 - antagonists & inhibitors | Incidence | Myocardial Reperfusion Injury - metabolism | Propensity Score | Heart Valve Prosthesis Implantation - adverse effects | Aged, 80 and over | Aortic Valve Stenosis - metabolism | Female | Aged | Aortic Valve Stenosis - surgery | Nuclear Receptor Subfamily 1, Group D, Member 1 - metabolism | Cohort Studies | Heart failure | Cardiac arrhythmia | Heart attacks | Heart surgery | Genes | Coronary artery | Clinical trials | Circadian rhythm | Patients | Clinical outcomes | Antagonism | Injury prevention | Ischemia | Coronary vessels | Surgery | Electrocardiography | Cardiology | Heart diseases
INFARCT SIZE | CLOCK GENES | HEART | MEDICINE, GENERAL & INTERNAL | CELLULAR BIOLOGY | ELEVATION | TIME | POSITION PAPER | EXPRESSION | CIRCADIAN DEPENDENCE | Signal Transduction | Humans | Middle Aged | Postoperative Complications - metabolism | Male | Treatment Outcome | Myocardial Reperfusion Injury - epidemiology | Postoperative Complications - epidemiology | Circadian Rhythm | Case-Control Studies | Nuclear Receptor Subfamily 1, Group D, Member 1 - antagonists & inhibitors | Incidence | Myocardial Reperfusion Injury - metabolism | Propensity Score | Heart Valve Prosthesis Implantation - adverse effects | Aged, 80 and over | Aortic Valve Stenosis - metabolism | Female | Aged | Aortic Valve Stenosis - surgery | Nuclear Receptor Subfamily 1, Group D, Member 1 - metabolism | Cohort Studies | Heart failure | Cardiac arrhythmia | Heart attacks | Heart surgery | Genes | Coronary artery | Clinical trials | Circadian rhythm | Patients | Clinical outcomes | Antagonism | Injury prevention | Ischemia | Coronary vessels | Surgery | Electrocardiography | Cardiology | Heart diseases
Journal Article
04/2018, ISBN 9783319664828
Book Chapter
1981, Travaux d'humanisme et Renaissance, Volume no 187, 2 v. (xiv, 1442 p.)
Book
The Journal of Membrane Biology, ISSN 0022-2631, 10/2017, Volume 250, Issue 5, pp. 471 - 481
Cardiac electrophysiology is regulated by the autonomic nervous system, and this has both pathophysiological, and possibly therapeutic importance. Furthermore,...
Life Sciences | Biochemistry, general | Temperature | Human Physiology | Cardiac electrophysiology | Autonomic regulation | ARRHYTHMIAS | NERVOUS-SYSTEM | PHYSIOLOGY | MYOCYTES | BIOCHEMISTRY & MOLECULAR BIOLOGY | CURRENTS | ATRIAL-FIBRILLATION | CELL BIOLOGY | SLICES | IONIC MECHANISMS | K+ CHANNEL | MOUSE HEARTS | Atrial Function - physiology | Microelectrodes | Ventricular Function - physiology | Mexiletine - pharmacology | Heart Atria | Male | Atrial Function - drug effects | Heart Ventricles | Carbachol - pharmacology | Animals | Isoproterenol - pharmacology | Myocardium | Female | Mice | Electrophysiological Phenomena | Electrophysiologic Techniques, Cardiac | Ventricular Function - drug effects | Medical colleges | Analysis | Heart | Conduction | Electrophysiology | Activation | Pharmacology | Velocity | Sodium | Carbachol | Autonomic nervous system | Modulation | Ion channels | Ventricle | Atria | Heart diseases
Life Sciences | Biochemistry, general | Temperature | Human Physiology | Cardiac electrophysiology | Autonomic regulation | ARRHYTHMIAS | NERVOUS-SYSTEM | PHYSIOLOGY | MYOCYTES | BIOCHEMISTRY & MOLECULAR BIOLOGY | CURRENTS | ATRIAL-FIBRILLATION | CELL BIOLOGY | SLICES | IONIC MECHANISMS | K+ CHANNEL | MOUSE HEARTS | Atrial Function - physiology | Microelectrodes | Ventricular Function - physiology | Mexiletine - pharmacology | Heart Atria | Male | Atrial Function - drug effects | Heart Ventricles | Carbachol - pharmacology | Animals | Isoproterenol - pharmacology | Myocardium | Female | Mice | Electrophysiological Phenomena | Electrophysiologic Techniques, Cardiac | Ventricular Function - drug effects | Medical colleges | Analysis | Heart | Conduction | Electrophysiology | Activation | Pharmacology | Velocity | Sodium | Carbachol | Autonomic nervous system | Modulation | Ion channels | Ventricle | Atria | Heart diseases
Journal Article
American Journal of Physiology, ISSN 0363-6143, 05/2018, Volume 314, Issue 5, p. C616
G protein-gated inwardly rectifying K+ (GIRK) channels are the major inwardly rectifying K+ currents in cardiac atrial myocytes and an important determinant of...
Heart | Conduction | Transcription | Potassium channels (inwardly-rectifying) | Electrophysiology | Action potential | Myocytes | Gene expression | Proteins | Electrical currents | Clonal deletion | Rodents | Isoforms | Acetylcholine | Potassium | Potassium currents
Heart | Conduction | Transcription | Potassium channels (inwardly-rectifying) | Electrophysiology | Action potential | Myocytes | Gene expression | Proteins | Electrical currents | Clonal deletion | Rodents | Isoforms | Acetylcholine | Potassium | Potassium currents
Journal Article
European Radiology, ISSN 0938-7994, 6/2019, Volume 29, Issue 6, pp. 3027 - 3035
To evaluate whether the epicardial adipose tissue (EAT) phenotype is associated with the electrophysiological properties of adjacent atrial myocardium in...
Adipose tissue | Medicine & Public Health | Diagnostic Radiology | Atrial fibrillation | Fibrosis | Internal Medicine | Inflammation | Interventional Radiology | Imaging / Radiology | Ultrasound | Neuroradiology | PERICARDIAL FAT | VOLUME | ABLATION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | COMPUTED-TOMOGRAPHY | SEVERITY | Prospective Studies | Follow-Up Studies | Humans | Middle Aged | Risk Factors | Adipose Tissue - pathology | Tomography, X-Ray Computed - methods | Male | Atrial Fibrillation - physiopathology | Atrial Fibrillation - surgery | Heart Atria - diagnostic imaging | Catheter Ablation - methods | Female | Pericardium - diagnostic imaging | Aged | Heart Atria - physiopathology | Atrial Fibrillation - diagnosis | Body Surface Potential Mapping - methods | Cardiac arrhythmia | Electric potential | Pathogenesis | Mapping | Risk factors | Fibrillation | Computed tomography | Voltage | Tomography | Electrocardiography | Attenuation | Heart diseases | Phenotypes | Medical instruments | Health risks | Risk analysis | Ablation | Patients | Coronary artery disease | Catheters | Computation | Myocardium | Cardiovascular diseases
Adipose tissue | Medicine & Public Health | Diagnostic Radiology | Atrial fibrillation | Fibrosis | Internal Medicine | Inflammation | Interventional Radiology | Imaging / Radiology | Ultrasound | Neuroradiology | PERICARDIAL FAT | VOLUME | ABLATION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | COMPUTED-TOMOGRAPHY | SEVERITY | Prospective Studies | Follow-Up Studies | Humans | Middle Aged | Risk Factors | Adipose Tissue - pathology | Tomography, X-Ray Computed - methods | Male | Atrial Fibrillation - physiopathology | Atrial Fibrillation - surgery | Heart Atria - diagnostic imaging | Catheter Ablation - methods | Female | Pericardium - diagnostic imaging | Aged | Heart Atria - physiopathology | Atrial Fibrillation - diagnosis | Body Surface Potential Mapping - methods | Cardiac arrhythmia | Electric potential | Pathogenesis | Mapping | Risk factors | Fibrillation | Computed tomography | Voltage | Tomography | Electrocardiography | Attenuation | Heart diseases | Phenotypes | Medical instruments | Health risks | Risk analysis | Ablation | Patients | Coronary artery disease | Catheters | Computation | Myocardium | Cardiovascular diseases
Journal Article
Diabetes, ISSN 0012-1797, 02/2016, Volume 65, Issue 2, pp. e1 - e2
Journal Article
European radiology, ISSN 0938-7994, 08/2019, pp. 1 - 11
This study was conducted in order to evaluate the accuracy of a compressed sensing (CS) real-time single-breath-hold cine sequence for the assessment of left...
Heart | Visualization | Sequences | Magnetic resonance | Disorders | Workflow | Real time | Heart valves | Image acquisition | Training | Magnetic resonance imaging | Regurgitation | Electrocardiography | Time compression | Ventricle | Detection | Ejection
Heart | Visualization | Sequences | Magnetic resonance | Disorders | Workflow | Real time | Heart valves | Image acquisition | Training | Magnetic resonance imaging | Regurgitation | Electrocardiography | Time compression | Ventricle | Detection | Ejection
Journal Article
Diabetes Care, ISSN 0149-5992, 2014, Volume 37, Issue 5, pp. 1425 - 1431
OBJECTIVERenal dysfunction is a key risk factor for all-cause mortality in patients with type 2 diabetes (T2D). Circulating tumor necrosis factor receptor 1...
PATHWAYS | TUMOR-NECROSIS-FACTOR | CARDIOVASCULAR EVENTS | ENDOCRINOLOGY & METABOLISM | RECEPTORS 1 | RISK | MELLITUS | OUTCOMES | Kidney Failure, Chronic - mortality | Prognosis | Prospective Studies | Receptors, Tumor Necrosis Factor, Type I - blood | Follow-Up Studies | Humans | Middle Aged | Risk Factors | Male | Biomarkers - blood | Diabetic Nephropathies - blood | Glomerular Filtration Rate - physiology | Cause of Death | Diabetic Nephropathies - mortality | Diabetes Mellitus, Type 2 - blood | Kidney Failure, Chronic - blood | Diabetes Mellitus, Type 2 - mortality | Adult | Female | Aged | Diabetes Mellitus, Type 2 - complications | Kidney Failure, Chronic - etiology | Type 2 diabetes | Chronic kidney failure | Tumor necrosis factor | Patient outcomes | Mortality | France | Risk factors
PATHWAYS | TUMOR-NECROSIS-FACTOR | CARDIOVASCULAR EVENTS | ENDOCRINOLOGY & METABOLISM | RECEPTORS 1 | RISK | MELLITUS | OUTCOMES | Kidney Failure, Chronic - mortality | Prognosis | Prospective Studies | Receptors, Tumor Necrosis Factor, Type I - blood | Follow-Up Studies | Humans | Middle Aged | Risk Factors | Male | Biomarkers - blood | Diabetic Nephropathies - blood | Glomerular Filtration Rate - physiology | Cause of Death | Diabetic Nephropathies - mortality | Diabetes Mellitus, Type 2 - blood | Kidney Failure, Chronic - blood | Diabetes Mellitus, Type 2 - mortality | Adult | Female | Aged | Diabetes Mellitus, Type 2 - complications | Kidney Failure, Chronic - etiology | Type 2 diabetes | Chronic kidney failure | Tumor necrosis factor | Patient outcomes | Mortality | France | Risk factors
Journal Article
Diabetologia, ISSN 0012-186X, 4/2016, Volume 59, Issue 4, pp. 861 - 862
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1007/s00125-015-3840-0
Type 2 diabetes | Medicine & Public Health | Human Physiology | Atrial fibrillation | Metabolic Diseases | Internal Medicine | Diabetic nephropathy | Albuminuria | FIBRILLATION | ENDOCRINOLOGY & METABOLISM | RISK | CORRELATE | Albuminuria - complications | Humans | Atrial Fibrillation - etiology | Hypertension - complications | Female | Male | Blood Pressure - physiology | Diabetes Mellitus, Type 2 - complications | Complications and side effects | Diabetic nephropathies | Life Sciences | Human health and pathology
Type 2 diabetes | Medicine & Public Health | Human Physiology | Atrial fibrillation | Metabolic Diseases | Internal Medicine | Diabetic nephropathy | Albuminuria | FIBRILLATION | ENDOCRINOLOGY & METABOLISM | RISK | CORRELATE | Albuminuria - complications | Humans | Atrial Fibrillation - etiology | Hypertension - complications | Female | Male | Blood Pressure - physiology | Diabetes Mellitus, Type 2 - complications | Complications and side effects | Diabetic nephropathies | Life Sciences | Human health and pathology
Journal Article
Biochemistry Research International, ISSN 2090-2247, 2012, Volume 2012, pp. 951539 - 12
Anthracyclines remain the cornerstone of treatment in many malignancies but these agents have a cumulative dose relationship with cardiotoxicity. Development...
Review
Review
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2012, Volume 7, Issue 8, p. e41836
Aims: Metabolic syndrome induces cardiac dysfunction associated with mitochondria abnormalities. As low levels of carbon monoxide (CO) may improve myocardial...
OXIDATIVE STRESS | BIOGENESIS | MOLECULE | PROTEIN-KINASE | RESPIRATION | MULTIDISCIPLINARY SCIENCES | IN-VIVO | MICE | HEME OXYGENASE-1 | AUTOPHAGY | EXPRESSION | Dietary Fats - adverse effects | Mitochondria, Heart - metabolism | Heart Diseases - metabolism | Heart Diseases - physiopathology | Humans | Myocardial Contraction - drug effects | Metabolic Syndrome - metabolism | Metabolic Syndrome - chemically induced | Metabolic Syndrome - drug therapy | Autophagy - drug effects | Heart Diseases - etiology | Animals | Carbon Monoxide - pharmacology | Signal Transduction - drug effects | Metabolic Syndrome - physiopathology | Female | Heart Diseases - drug therapy | Mice | Organometallic Compounds - pharmacology | Antimetabolites - pharmacology | Heart | Biosynthesis | Carbon monoxide | Oxidative stress | Cardiomyopathy | Kinases | Metabolic syndrome | Autophagy | ADP | High fat diet | Proteins | Signal transduction | Mitochondria | Ischemia | Rodents | Physiology | Membrane potential | Heart diseases | Fitness equipment | Abnormalities | Contractility | Electron microscopy | Insulin | Muscle contraction | Signaling | Diet | Hypoxia | Diabetes | Ventricle | Electron transport | Metabolic disorders | Phagocytosis
OXIDATIVE STRESS | BIOGENESIS | MOLECULE | PROTEIN-KINASE | RESPIRATION | MULTIDISCIPLINARY SCIENCES | IN-VIVO | MICE | HEME OXYGENASE-1 | AUTOPHAGY | EXPRESSION | Dietary Fats - adverse effects | Mitochondria, Heart - metabolism | Heart Diseases - metabolism | Heart Diseases - physiopathology | Humans | Myocardial Contraction - drug effects | Metabolic Syndrome - metabolism | Metabolic Syndrome - chemically induced | Metabolic Syndrome - drug therapy | Autophagy - drug effects | Heart Diseases - etiology | Animals | Carbon Monoxide - pharmacology | Signal Transduction - drug effects | Metabolic Syndrome - physiopathology | Female | Heart Diseases - drug therapy | Mice | Organometallic Compounds - pharmacology | Antimetabolites - pharmacology | Heart | Biosynthesis | Carbon monoxide | Oxidative stress | Cardiomyopathy | Kinases | Metabolic syndrome | Autophagy | ADP | High fat diet | Proteins | Signal transduction | Mitochondria | Ischemia | Rodents | Physiology | Membrane potential | Heart diseases | Fitness equipment | Abnormalities | Contractility | Electron microscopy | Insulin | Muscle contraction | Signaling | Diet | Hypoxia | Diabetes | Ventricle | Electron transport | Metabolic disorders | Phagocytosis
Journal Article
Diabetologia, ISSN 0012-186X, 12/2018, Volume 61, Issue 12, pp. 2643 - 2653
Aims/hypothesisN-terminal pro-B-type natriuretic peptide (NT-proBNP) is the gold standard prognostic biomarker for diagnosis and occurrence of heart failure....
Heart failure | Type 2 diabetes | NT-proBNP | Prognosis | BNP | Adrenomedullin | Biomarkers | CARDIOVASCULAR EVENTS | RISK | MELLITUS | MIDREGIONAL PROADRENOMEDULLIN | GENE | DISEASE | ENDOCRINOLOGY & METABOLISM | OUTCOMES | ASSOCIATION | Prospective Studies | Humans | Middle Aged | Adrenomedullin - blood | Male | Biomarkers - blood | Heart Failure - pathology | Heart Failure - blood | Neuropeptides - blood | Diabetes Mellitus, Type 2 - blood | Peptide Fragments - blood | Female | Aged | Diabetes Mellitus, Type 2 - pathology | Natriuretic Peptide, Brain - blood | Heart | Vasodilators | Analysis | Natriuretic peptides | Brain natriuretic peptide | Plasma | Epidermal growth factor receptors | Diabetes mellitus | Cardiovascular disease | Congestive heart failure | Coronary artery disease | Risk factors | Heart rate | Vasoactive agents | Diabetes | Health risk assessment | Diabetes mellitus (non-insulin dependent) | Proteinuria
Heart failure | Type 2 diabetes | NT-proBNP | Prognosis | BNP | Adrenomedullin | Biomarkers | CARDIOVASCULAR EVENTS | RISK | MELLITUS | MIDREGIONAL PROADRENOMEDULLIN | GENE | DISEASE | ENDOCRINOLOGY & METABOLISM | OUTCOMES | ASSOCIATION | Prospective Studies | Humans | Middle Aged | Adrenomedullin - blood | Male | Biomarkers - blood | Heart Failure - pathology | Heart Failure - blood | Neuropeptides - blood | Diabetes Mellitus, Type 2 - blood | Peptide Fragments - blood | Female | Aged | Diabetes Mellitus, Type 2 - pathology | Natriuretic Peptide, Brain - blood | Heart | Vasodilators | Analysis | Natriuretic peptides | Brain natriuretic peptide | Plasma | Epidermal growth factor receptors | Diabetes mellitus | Cardiovascular disease | Congestive heart failure | Coronary artery disease | Risk factors | Heart rate | Vasoactive agents | Diabetes | Health risk assessment | Diabetes mellitus (non-insulin dependent) | Proteinuria
Journal Article
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