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Nature, ISSN 0028-0836, 2017, Volume 552, Issue 7683, pp. 1 - 5
Journal Article
2003, 1a ed., ISBN 9788589126311, 62
Book
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2287 - 12
Journal Article
Cancer Cell, ISSN 1535-6108, 07/2018, Volume 34, Issue 1, pp. 148 - 162.e7
Targeting HER2 is effective in 24% of amplified metastatic colorectal cancer; however, secondary resistance occurs in most of the cases. We studied the... 
trastuzumab | targeted therapy | rapid autopsy | colorectal cancer | clonal evolution | HER2 amplification | lapatinib | liquid biopsy | ctDNA | resistance | BREAST-CANCER | HETEROGENEITY | PIK3CA MUTATIONS | THERAPY | AMPLIFICATION | SOLID TUMORS | GENE | ONCOLOGY | ACQUIRED-RESISTANCE | EGFR BLOCKADE | PATHOLOGICAL COMPLETE RESPONSE | CELL BIOLOGY | Predictive Value of Tests | ras Proteins - genetics | Liquid Biopsy | Class I Phosphatidylinositol 3-Kinases - genetics | Receptor, ErbB-2 - genetics | Colorectal Neoplasms - genetics | Humans | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Tomography, X-Ray Computed | Protein Kinase Inhibitors - adverse effects | Time Factors | DNA Mutational Analysis | Clinical Decision-Making | Colorectal Neoplasms - drug therapy | Female | Adenocarcinoma - genetics | Receptor, ErbB-2 - antagonists & inhibitors | Tumor Cells, Cultured | Liver Neoplasms - secondary | Lapatinib - adverse effects | Liver Neoplasms - genetics | Risk Factors | Liver Neoplasms - drug therapy | Trastuzumab - adverse effects | Mice, Transgenic | Treatment Outcome | Colorectal Neoplasms - diagnostic imaging | Trastuzumab - administration & dosage | Mice, SCID | Adenocarcinoma - drug therapy | Liver Neoplasms - diagnostic imaging | Adenocarcinoma - secondary | Disease Progression | Magnetic Resonance Imaging | Protein Kinase Inhibitors - administration & dosage | Drug Resistance, Neoplasm - genetics | Animals | Gene Amplification | Signal Transduction - drug effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Progression-Free Survival | Italy | Mice, Inbred NOD | Adenocarcinoma - diagnostic imaging | Colorectal Neoplasms - pathology | Lapatinib - administration & dosage | Genetic research | Genetic aspects | Metastasis | Analysis | Colorectal cancer | Cancer
Journal Article
CLINICAL CANCER RESEARCH, ISSN 1078-0432, 10/2019, Volume 25, Issue 20, pp. 6243 - 6259
Purpose: Patient-derived xenograft (PDX) models accurately recapitulate the tumor of origin in terms of histopathology, genomic landscape, and therapeutic... 
COLON-CANCER | DRUG-SENSITIVITY | IN-VITRO | INHIBITION | MODELS | ONCOLOGY | CONSENSUS MOLECULAR SUBTYPES | RESISTANCE | PRECISION MEDICINE | EGFR BLOCKADE | TUMOR HETEROGENEITY
Journal Article
Clinical Colorectal Cancer, ISSN 1533-0028, 06/2019, Volume 18, Issue 2, pp. 91 - 101.e3
The diagnosis of colorectal cancer (CRC) is routinely accomplished through histopathologic examination. Prognostic information and treatment decisions are... 
IDEA | Bioinformatics | Next generation sequencing | Colorectal cancer | Genetic alterations | Genetic aspects | Prognosis | Research | Gene mutations
Journal Article
Contrast Media & Molecular Imaging, ISSN 1555-4309, 07/2013, Volume 8, Issue 4, p. 350
  Despite spontaneous tumor growth in genetically engineered mice being one of the most recognized tools for the in vivo evaluation of novel diagnostic and... 
Journal Article
Contrast Media and Molecular Imaging, ISSN 1555-4309, 07/2013, Volume 8, Issue 4, pp. 350 - 360
Despite spontaneous tumor growth in genetically engineered mice being one of the most recognized tools for the in vivo evaluation of novel diagnostic and... 
Breast cancer
Journal Article
Cancer Immunology Research, ISSN 2326-6066, 02/2017, Volume 5, Issue 3 Supplement, pp. PR13 - PR13
Journal Article
ESMO Open, ISSN 2059-7029, 11/2019, Volume 4, Issue 6, p. e000572
BackgroundThe analysis of circulating free tumour DNA (ctDNA) in blood, commonly referred as liquid biopsy, is being used to characterise patients with solid... 
Journal Article
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