X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (63) 63
oncology (45) 45
lung neoplasms - genetics (30) 30
cancer (29) 29
male (28) 28
female (24) 24
lung cancer (22) 22
tumors (20) 20
aged (19) 19
dna methylation (19) 19
index medicus (19) 19
middle aged (18) 18
lung neoplasms - pathology (17) 17
mutation (17) 17
expression (15) 15
gene (15) 15
methylation (15) 15
prognosis (15) 15
cell line, tumor (14) 14
animals (13) 13
carcinoma (13) 13
dna (13) 13
gene expression regulation, neoplastic (13) 13
genetics & heredity (13) 13
lung neoplasms - metabolism (12) 12
mice (12) 12
biochemistry & molecular biology (11) 11
carcinoma, non-small-cell lung - genetics (11) 11
immunohistochemistry (11) 11
mutations (11) 11
adenocarcinoma (10) 10
adult (10) 10
carcinoma, squamous cell - genetics (10) 10
cell biology (10) 10
gene expression (10) 10
head and neck neoplasms - genetics (10) 10
adenocarcinoma - genetics (9) 9
càncer de pulmó (9) 9
genetic aspects (9) 9
promoter regions, genetic (9) 9
analysis (8) 8
carcinoma, squamous cell - pathology (8) 8
nuclear proteins - genetics (8) 8
protein (8) 8
carcinoma, non-small-cell lung - pathology (7) 7
epigenetics (7) 7
head and neck neoplasms - pathology (7) 7
loss of heterozygosity (7) 7
oligonucleotide array sequence analysis (7) 7
polymerase chain reaction (7) 7
tumor-suppressor (7) 7
adn (6) 6
aged, 80 and over (6) 6
article (6) 6
cpg islands - genetics (6) 6
dna, neoplasm - genetics (6) 6
down-regulation (6) 6
gene silencing (6) 6
genes, tumor suppressor (6) 6
identification (6) 6
inactivation (6) 6
metilació (6) 6
neoplasm staging (6) 6
p53 (6) 6
p53 mutations (6) 6
peutz-jeghers-syndrome (6) 6
protein-serine-threonine kinases - genetics (6) 6
squamous-cell carcinoma (6) 6
adenocarcinoma - pathology (5) 5
base sequence (5) 5
biomarkers, tumor - genetics (5) 5
colorectal neoplasms - genetics (5) 5
multidisciplinary sciences (5) 5
pathology (5) 5
pathway (5) 5
promoter hypermethylation (5) 5
promoter regions, genetic - genetics (5) 5
proteins (5) 5
research (5) 5
signal transduction (5) 5
somatic mutations (5) 5
survival (5) 5
tumor-suppressor gene (5) 5
activation (4) 4
alleles (4) 4
biomarkers, tumor - analysis (4) 4
breast-cancer (4) 4
carcinoma, non-small-cell lung - mortality (4) 4
cell transformation, neoplastic - genetics (4) 4
cell-lines (4) 4
cells (4) 4
chemotherapy (4) 4
colorectal-cancer (4) 4
disease models, animal (4) 4
disease progression (4) 4
dna mutational analysis (4) 4
dna, mitochondrial - genetics (4) 4
dna, neoplasm - metabolism (4) 4
gene expression profiling (4) 4
genes (4) 4
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Cancer Research, ISSN 0008-5472, 07/2017, Volume 77, Issue 13 Supplement, pp. 5073 - 5073
Journal Article
Cancer Cell, ISSN 1535-6108, 08/2012, Volume 22, Issue 2, pp. 222 - 234
Here, we have investigated the role of the Notch pathway in the generation and maintenance of Kras -driven non-small cell lung carcinomas (NSCLCs). We... 
Journal Article
by George, Julie and Lim, Jing Shan and Jang, Se Jin and Cun, Yupeng and Ozretia, Luka and Kong, Gu and Leenders, Frauke and Lu, Xin and Fernández-Cuesta, Lynnette and Bosco, Graziella and Müller, Christian and Dahmen, Ilona and Jahchan, Nadine S and Park, Kwon-Sik and Yang, Dian and Karnezis, Anthony N and Vaka, Dedeepya and Torres, Angela and Wang, Maia Segura and Korbel, Jan O and Menon, Roopika and Chun, Sung-Min and Kim, Deokhoon and Wilkerson, Matt and Hayes, Neil and Engelmann, David and Pützer, Brigitte and Bos, Marc and Michels, Sebastian and Vlasic, Ignacija and Seidel, Danila and Pinther, Berit and Schaub, Philipp and Becker, Christian and Altmüller, Janine and Yokota, Jun and Kohno, Takashi and Iwakawa, Reika and Tsuta, Koji and Noguchi, Masayuki and Muley, Thomas and Hoffmann, Hans and Schnabel, Philipp A and Petersen, Iver and Chen, Yuan and Soltermann, Alex and Tischler, Verena and Choi, Chang-Min and Kim, Yong-Hee and Massion, Pierre P and Zou, Yong and Jovanovic, Dragana and Kontic, Milica and Wright, Gavin M and Russell, Prudence A and Solomon, Benjamin and Koch, Ina and Lindner, Michael and Muscarella, Lucia A and La Torre, Annamaria and Field, John K and Jakopovic, Marko and Knezevic, Jelena and Castaños-Vélez, Esmeralda and Roz, Luca and Pastorino, Ugo and Brustugun, Odd-Terje and Lund-Iversen, Marius and Thunnissen, Erik and Köhler, Jens and Schuler, Martin and Botling, Johan and Sandelin, Martin and Sanchez-Cespedes, Montserrat and Salvesen, Helga B and Achter, Viktor and Lang, Ulrich and Bogus, Magdalena and Schneider, Peter M and Zander, Thomas and Ansén, Sascha and Hallek, Michael and Wolf, Jürgen and Vingron, Martin and Yatabe, Yasushi and Travis, William D and Nürnberg, Peter and Reinhardt, Christian and Perner, Sven and Heukamp, Lukas and Büttner, Reinhard and Haas, Stefan A and Brambilla, Elisabeth and Peifer, Martin and Sage, Julien and Thomas, Roman K and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för immunologi, genetik och patologi and Lungmedicin och allergologi and Uppsala universitet and Institutionen för medicinska vetenskaper
Nature, ISSN 0028-0836, 08/2015, Volume 524, Issue 7563, pp. 47 - 53
We have sequenced the genomes of 110 small cell lung cancers (SCLC), one of the deadliest human cancers. In nearly all the tumours analysed we found bi-allelic... 
NEUROENDOCRINE TUMORS | PATHWAY | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | IN-VIVO | GENES | CYCLE ARREST | NOTCH | C-KIT | MUTATIONS | CARCINOMA | Neurosecretory Systems - pathology | Receptors, Notch - metabolism | Chromosome Breakpoints | Genomics | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | Male | Receptors, Notch - genetics | Gene Expression Profiling | Tumor Suppressor Protein p53 - genetics | Small Cell Lung Carcinoma - metabolism | Tumor Suppressor Proteins - genetics | Neurosecretory Systems - metabolism | Female | Nuclear Proteins - genetics | Disease Models, Animal | Lung Neoplasms - genetics | Signal Transduction - genetics | Small Cell Lung Carcinoma - genetics | DNA-Binding Proteins - genetics | Mutation - genetics | Genome, Human - genetics | Small Cell Lung Carcinoma - pathology | Tumor Protein p73 | Animals | Cyclin D1 - genetics | Retinoblastoma Protein - genetics | Alleles | Cell Line, Tumor | Mice | Gene mutations | Analysis | Exome sequencing | Lung cancer, Small cell | Genetic aspects | Drug therapy | Cancer | Pathogenesis | Lung cancer | Genomes | Mutation | Kinases | Gene expression | Cancer therapies | Tumors | Clinical Medicine | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Cancer and Oncology | Klinisk medicin | Cancer och onkologi
Journal Article
Nature, ISSN 0028-0836, 07/2017, Volume 547, Issue 7662, p. 246
This corrects the article DOI: 10.1038/nature04585. 
Journal Article
Nature, ISSN 0028-0836, 07/2017, Volume 547, Issue 7662, p. 246
Journal Article
Nature, ISSN 0028-0836, 07/2017, Volume 547, Issue 7662, pp. 246 - 246
Journal Article
Journal of Thoracic Oncology, ISSN 1556-0864, 02/2011, Volume 6, Issue 2, pp. 244 - 285
Journal Article
Nature Medicine, ISSN 1078-8956, 03/2016, Volume 22, Issue 3, pp. 270 - 277
Patients with advanced Kirsten rat sarcoma viral oncogene homolog (KRAS)-mutant lung adenocarcinoma are currently treated with standard chemotherapy because of... 
MEDICINE, RESEARCH & EXPERIMENTAL | TYROSINE KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | C-RAF | TUMOR | DOMAIN RECEPTOR 1 | CELL-SURVIVAL | CANCER | CELL BIOLOGY | K-RAS ONCOGENE | PATHWAY | POOR-PROGNOSIS | EXPRESSION | Neoplasm Transplantation | Paclitaxel - pharmacology | Adenocarcinoma of Lung | Apoptosis - drug effects | Proto-Oncogene Proteins p21(ras) - genetics | Humans | Middle Aged | Male | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Receptors, Notch | Antibodies, Monoclonal, Humanized - pharmacology | Neoplasms, Experimental - genetics | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Female | Adenocarcinoma - genetics | Gene Expression Regulation, Neoplastic - drug effects | Gene Expression Regulation, Neoplastic - genetics | Lung Neoplasms - genetics | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | Antibodies, Monoclonal | Cisplatin - pharmacology | Discoidin Domain Receptor 1 | Reverse Transcriptase Polymerase Chain Reaction | Dasatinib - pharmacology | Animals | Membrane Proteins - antagonists & inhibitors | Signal Transduction - drug effects | Cell Line, Tumor | Aged | Cell Proliferation - drug effects | Mice | Mutation | Adenocarcinoma | Care and treatment | Physiological aspects | Development and progression | Genetic aspects | Cellular signal transduction | Research | Gene expression | Signaling | Inhibitor drugs | Drug therapy | Lung cancer
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 11/2013, Volume 31, Issue 32, pp. 4140 - 4147
Journal Article