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1. Full Text Radiation to the Gastric Fundus Increases the Risk of Anastomotic Leakage After Esophagectomy
by Goense, Lucas, MD and van Rossum, Peter S.N., MD and Ruurda, Jelle P., MD, PhD and van Vulpen, Marco, MD, PhD and Mook, Stella, MD, PhD and Meijer, Gert J., PhD and van Hillegersberg, Richard, MD, PhD
Annals of Thoracic Surgery, ISSN 0003-4975, 2016, Volume 102, Issue 6, pp. 1798 - 1804
Background Concerns have been raised regarding the toxicity of neoadjuvant chemoradiotherapy (nCRT) for esophageal cancer that could contribute to an increased... 
Surgery | Cardiothoracic Surgery | Journal Article | POSTOPERATIVE PULMONARY COMPLICATIONS | MORTALITY | SURGERY | LIMITED TRANSHIATAL RESECTION | CARDIAC & CARDIOVASCULAR SYSTEMS | MORBIDITY | RESPIRATORY SYSTEM | ADENOCARCINOMA | JUNCTIONAL CANCER | PREOPERATIVE CHEMORADIOTHERAPY | NEOADJUVANT CHEMORADIATION | RESECTABLE ESOPHAGEAL | Radiotherapy Dosage | Esophagectomy - adverse effects | Chemoradiotherapy - adverse effects | Humans | Middle Aged | Anastomotic Leak - etiology | Male | Esophageal Neoplasms - radiotherapy | Esophageal Neoplasms - surgery | Neoadjuvant Therapy - adverse effects | Female | Aged | Gastric Fundus | Cohort Studies | Radiation | Index Medicus | Abridged Index Medicus
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2. Full Text Calibration and discriminatory accuracy of prognosis calculation for breast cancer with the online Adjuvant! program: a hospital-based retrospective cohort study
by Mook, Stella, MD and Schmidt, Marjanka K, PhD and Rutgers, Emiel J, Prof and van de Velde, Anthonie O, BSc and Visser, Otto, MD and Rutgers, Sterre M, MSc and Armstrong, Nicola, PhD and van't Veer, Laura J, Dr and Ravdin, Peter M, MD
Lancet Oncology, The, ISSN 1470-2045, 2009, Volume 10, Issue 11, pp. 1070 - 1076
Summary Background Adjuvant! is a web-based program that calculates individualised 10-year survival probabilities and predicted benefit of adjuvant systemic... 
Hematology, Oncology and Palliative Medicine | STATEMENT | SURVIVAL | THERAPY | MODELS | ONCOLOGY | ASSIST | INDEX | CARCINOMA | Predictive Value of Tests | Breast Neoplasms - secondary | Age Factors | Humans | Middle Aged | Netherlands - epidemiology | Antineoplastic Agents - therapeutic use | Receptors, Estrogen - analysis | Patient Selection | Time Factors | Online Systems - standards | Adult | Female | Registries | Retrospective Studies | Chemotherapy, Adjuvant | Reproducibility of Results | Risk Assessment | Decision Support Techniques | Kaplan-Meier Estimate | Proportional Hazards Models | Treatment Outcome | Hospitalization | Lymphatic Metastasis | Calibration | Breast Neoplasms - drug therapy | Discriminant Analysis | Disease-Free Survival | Models, Biological | Breast Neoplasms - mortality | Aged | Breast Neoplasms - diagnosis | Internet | Neoplasm Staging | Practice Guidelines as Topic | Breast cancer | Prognosis | Research | Oncology, Experimental | Cancer
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3. Full Text Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney
by Wain, Louise V and Vaez, Ahmad and Jansen, Rick and Joehanes, Roby and van der Most, Peter J and Erzurumluoglu, A Mesut and O'Reilly, Paul F and Cabrera, Claudia P and Warren, Helen R and Rose, Lynda M and Verwoert, Germaine C and Hottenga, Jouke-Jan and Strawbridge, Rona J and Esko, Tonu and Arking, Dan E and Hwang, Shih-Jen and Guo, Xiuqing and Kutalik, Zoltan and Trompet, Stella and Shrine, Nick and Teumer, Alexander and Ried, Janina S and Bis, Joshua C and Smith, Albert V and Amin, Najaf and Nolte, Ilja M and Lyytikäinen, Leo-Pekka and Mahajan, Anubha and Wareham, Nicholas J and Hofer, Edith and Joshi, Peter K and Kristiansson, Kati and Traglia, Michela and Havulinna, Aki S and Goel, Anuj and Nalls, Mike A and Sõber, Siim and Vuckovic, gana and Luan, Jian'an and Del Greco M, Fabiola and Ayers, Kristin L and Marrugat, Jaume and Ruggiero, Daniela and Lopez, Lorna M and Niiranen, Teemu and Enroth, Stefan and Jackson, Anne U and Nelson, Christopher P and Huffman, Jennifer E and Zhang, Weihua and Marten, Jonathan and Gandin, Ilaria and Harris, Sarah E and Zemunik, Tatijana and Lu, Yingchang and Evangelou, Evangelos and Shah, Nabi and de Borst, Martin H and Mangino, Massimo and Prins, Bram P and Campbell, Archie and Li-Gao, Ruifang and Chauhan, Ganesh and Oldmeadow, Christopher and Abecasis, Gonçalo and Abedi, Maryam and Barbieri, Caterina M and Barnes, Michael R and Batini, Chiara and Beilby, John and Blake, Tineka and Boehnke, Michael and Bottinger, Erwin P and Braund, Peter S and Brown, Morris and Brumat, Marco and Campbell, Harry and Chambers, John C and Cocca, Massimiliano and Collins, Francis and Connell, John and Cordell, Heather J and Damman, Jeffrey J and Davies, Gail and de Geus, Eco J and de Mutsert, Renée and Deelen, Joris and Demirkale, Yusuf and Doney, Alex S F and Dörr, Marcus and Farrall, Martin and Ferreira, Teresa and Frånberg, Mattias and Gao, He and Gieaitis, Vilmantas and Gieger, Christian and Giulianini, Franco and Gow, Alan J and Hamsten, Anders and Harris, Tamara B and ... and Lifelines Cohort Study and Understanding Soc Sci Grp and BIOS Consortium and Understanding Society Scientific Group and Stockholms universitet and Numerisk analys och datalogi (NADA) and Naturvetenskapliga fakulteten
Hypertension, ISSN 0194-911X, 09/2017, Volume 70, Issue 3, pp. E4 - +
Elevated blood pressure is a major risk factor for cardiovascular disease and has a substantial genetic contribution. Genetic variation influencing blood... 
TARGET | blood pressure | COMMON VARIANTS | GWAS | METAANALYSIS | complex traits | PERIPHERAL-BLOOD | PULSE PRESSURE | INDIVIDUALS | CENTRIC ARRAY | cardiovascular risk | TRAITS | NETHERLANDS | hypertension | eSNP | PATHWAYS | DEPRESSION | PERIPHERAL VASCULAR DISEASE | REVEALS | Kardiologi | Clinical Medicine | Cardiac and Cardiovascular Systems | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin
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4. Full Text Contribution of human adipose tissue–derived stem cells and the secretome to the skin allograft survival in mice
by Lee, Sang Mook, MD, PhD and Lee, Sang Chul, MD, PhD and Kim, Say-June, MD, PhD
Journal of Surgical Research, ISSN 0022-4804, 2014, Volume 188, Issue 1, pp. 280 - 289
Abstract Background Despite considerable evidence showing the immunosuppressive properties of mesenchymal stem cells (MSCs) in vitro , such properties have not... 
Surgery | Mesenchymal stem cell (MSC) | Secretome | Adipose tissue-derived stem cell (ASC) | Skin transplantation | Immunological tolerance | Conditioned media | SURGERY | RAT | PROLIFERATION | TRANSPLANTATION | MESENCHYMAL STROMAL CELLS | IN-VITRO | REPAIR | DONOR BONE-MARROW | LIVER | DIFFERENTIATION | GRAFT SURVIVAL | Immunosuppression - methods | Humans | Mice, Inbred C57BL | Adipose Tissue - cytology | Graft Survival | Male | Mesenchymal Stromal Cells - secretion | Transplantation, Homologous | Culture Media, Conditioned | Lymphocytes - physiology | Transplantation Tolerance | Animals | Transplants - cytology | Interleukin-6 - blood | Skin Transplantation | Mice | Mice, Inbred BALB C | Mesenchymal Stem Cell Transplantation | Adipose tissues | Transplantation of organs, tissues, etc | Skin | Stem cells | Index Medicus
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5. Full Text The predictive value of the 70-gene signature for adjuvant chemotherapy in early breast cancer
by Knauer, Michael and Mook, Stella and Rutgers, Emiel J. T and Bender, Richard A and Hauptmann, Michael and van de Vijver, Marc J and Koornstra, Rutger H. T and Bueno-de-Mesquita, Jolien M and Linn, Sabine C and van 't Veer, Laura J
Breast cancer research and treatment, ISSN 0167-6806, 2010, Volume 120, Issue 3, pp. 655 - 661
Multigene assays have been developed and validated to determine the prognosis of breast cancer. In this study, we assessed the additional predictive value of... 
Oncology | Adjuvant chemotherapy | Breast cancer | Medicine & Public Health | Gene expression profiling | Risk assessment | PROGNOSIS-SIGNATURE | RANDOMIZED-TRIALS | DOXORUBICIN | GENE-EXPRESSION PROFILES | PATHOLOGICAL RESPONSE | VALIDATION | DOCETAXEL | THERAPY | NEOADJUVANT CHEMOTHERAPY | ONCOLOGY | GRADE INDEX | Breast Neoplasms - surgery | Predictive Value of Tests | Adenocarcinoma - pathology | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Gene Expression Profiling | Breast Neoplasms - metabolism | Adenocarcinoma - metabolism | Anthracyclines - administration & dosage | Antineoplastic Agents, Hormonal - therapeutic use | Adult | Female | Adenocarcinoma - genetics | Chemotherapy, Adjuvant | Neoplasm Proteins - genetics | Radiotherapy, Adjuvant | Adenocarcinoma - radiotherapy | Risk Assessment | Neoplasm Proteins - biosynthesis | Antineoplastic Agents, Hormonal - administration & dosage | Combined Modality Therapy | Tumor Burden | Adenocarcinoma - drug therapy | Breast Neoplasms - drug therapy | Neoplasm Metastasis - genetics | Taxoids - administration & dosage | Breast Neoplasms - radiotherapy | Breast Neoplasms - genetics | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Breast Neoplasms - pathology | Aged | Neoplasm Invasiveness - genetics | Neoplasm Staging | Adenocarcinoma - surgery | Care and treatment | Prognosis | Analysis | Genes | Adjuvant treatment | Genetic aspects | Gene expression | Health aspects | Cancer
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6. Full Text Metastatic potential of T1 breast cancer can be predicted by the 70-gene MammaPrint signature
by Mook, Stella and Knauer, Michael and Bueno-De-Mesquita, Jolien M and Retel, Valesca P and Wesseling, Jelle and Linn, Sabine C and Van'T Veer, Laura J and Rutgers, Emiel J
Annals of surgical oncology, ISSN 1068-9265, 05/2010, Volume 17, Issue 5, pp. 1406 - 1413
Background: Mammographic screening and increased awareness has led to an increase in the detection of T1 breast tumors that are generally estimated as having... 
Oncology | Surgery | Medicine & Public Health | Surgical Oncology | SURVIVAL | MORTALITY | STATEMENT | SURGERY | PROGNOSIS-SIGNATURE | THERAPY | ONCOLOGY | SIZE | TUMOR | VALIDATION | CONSENSUS | CARCINOMA | Carcinoma, Ductal, Breast - genetics | Carcinoma, Lobular - pathology | Receptors, Estrogen - metabolism | Prognosis | Oligonucleotide Array Sequence Analysis | Humans | Receptor, ErbB-2 - metabolism | Survival Rate | Gene Expression Profiling | Lymphatic Metastasis | Breast Neoplasms - metabolism | Receptors, Progesterone - metabolism | Neoplasm Metastasis | Breast Neoplasms - genetics | Carcinoma, Lobular - genetics | Breast Neoplasms - pathology | Biomarkers, Tumor - metabolism | Carcinoma, Ductal, Breast - pathology | Female | Biomarkers, Tumor - genetics | Carcinoma, Lobular - metabolism | Neoplasm Staging | Carcinoma, Ductal, Breast - metabolism | Breast cancer | Research | Metastasis | Oncology, Experimental | Adjuvant treatment | Cancer
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7. Full Text Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6
by Prins, B.P and Mead, T.J and Brody, Jennifer A and Sveinbjornsson, G and Ntalla, Ioanna and Bihlmeyer, Nathan A and Berg, Marten and Bork-Jensen, Jette and Cappellani, Stefania and Van Duijvenboden, S and Klena, N.T and Gabriel, G.C and Liu, X and Gulec, C and Grarup, Niels and Haessler, Jeff and Hall, Leanne M and Iorio, A and Isaacs, A and Li-Gao, R and Lin, Honghuang and Liu, Ching-Ti and Lyytikäinen, L.-P and Marten, Jonathan and Mei, H and Müller-Nurasyid, M and Orini, M and Padmanabhan, Sandosh and Radmanesh, Farid and Ramirez, J and Robino, Antonietta and Schwartz, M and Setten, Jessica and Smith, Albert and Verweij, N and Warren, Helen and Weiss, S and Alonso, Alvaro and Arnar, D.O and Bots, Michiel and Boer, Rudolf and Dominiczak, Anna and Eijgelsheim, M and Ellinor, Patrick and Guo, Xiuqing and Felix, Stephan and Harris, Tamara and Hayward, Caroline and Heckbert, Susan and Huang, P.L and Jukema, Jan Wouter and Kähönen, Mika and Kors, Jan and Lambiase, Pier and Launer, Lenore and Li, Man and Linneberg, Allan and Nelson, Christopher P and Pedersen, Oluf and Perez, M and Peters, Annette and Polasek, Ozren and Psaty, B.M and Raitakari, Olli and Rice, Kenneth and Rotter, Jerome I and Sinner, Moritz and Soliman, Elsayed Z and Spector, Timothy and Strauch, K and Thorsteinsdottir, Unnur and Tinker, A and Trompet, Stella and Uitterlinden, Ané and Vaartjes, Ilonca and Meer, Peter and Völker, Uwe and Völzke, Henry and Waldenberger, M and Wilson, James and Xie, Z and Asselbergs, F.W and Dörr, Marcus and Duijn, Cornelia and Gasparini, Paolo and Gudbjartsson, Daniel and Gudnason, V and Hansen, Torben and Kääb, Stefan and Kanters, J.K and Kooperberg, Charles and Lehtimäki, Terho and Lin, H.J and Lubitz, S.A and Mook-Kanamori, D.O and Conti, F.J and Newton-Cheh, Christopher and Rosand, J and Rudan, Igor and Samani, N.J and ...
Genome Biology, ISSN 1474-7596, 07/2018, Volume 19, Issue 1, pp. 87 - 17
textabstractBackground: Genome-wide association studies conducted on QRS duration, an electrocardiographic measurement associated with heart failure and sudden... 
Conduction | Exome chip | ADAMTS6 | Meta-analysis | MORTALITY | COMMON VARIANTS | POPULATION | VENTRICULAR CONDUCTION | ARRHYTHMIC DEATH | WORSENING HEART-FAILURE | PR INTERVAL | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | QRS DURATION | GENOME-WIDE ASSOCIATION | ELECTROCARDIOGRAPHIC PARAMETERS | Gene Expression | Genome-Wide Association Study | Heart Conduction System - metabolism | Humans | Middle Aged | Open Reading Frames | European Continental Ancestry Group | Male | Myocardium - pathology | Gene Expression Profiling | Genetic Loci | Whole Exome Sequencing | Exome | Animals | Heart Conduction System - physiopathology | Myocardium - metabolism | Electrocardiography | Female | Mice | Polymorphism, Single Nucleotide | African Continental Ancestry Group | ADAMTS Proteins - genetics | Connexin 43 - genetics | Heart | Secretion | Genomes | Connexin 43 | Kinases | Depolarization | Consortia | Software | Metalloproteinase | Gene loci | Mutation | Ventricle | Bioinformatics | Heart diseases | Genotypes
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8. Full Text Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity
by Kilpelainen, Tuomas O and Bentley, Amy R and Noordam, Raymond and Sung, Yun Ju and Schwander, Karen and Winkler, Thomas W and Jakupovic, Hermina and Chasman, Daniel I and Manning, Alisa and Ntalla, Ioanna and Aschard, Hugues and Brown, Michael R and de las Fuentes, Lisa and Franceschini, Nora and Guo, Xiuqing and Vojinovic, Dina and Aslibekyan, Stella and Feitosa, Mary F and Kho, Minjung and Musani, Solomon K and Richard, Melissa and Wang, Heming and Wang, Zhe and Bartz, Traci M and Bielak, Lawrence F and Campbell, Archie and Smith, Albert V and Amini, Marzyeh and Zhao, Jing Hua and Nolte, Ilja M and van der Most, Peter J and Verweij, Niek and de Vries, Paul S and Demirkan, Ayse and Alizadeh, Behrooz Z and Boezen, H. Marike and Franke, Lude and Navis, Gerjan and Rots, Marianne and Swertz, Morris and Wolffenbuttel, Bruce H. R and Wijmenga, Cisca and Snieder, Harold and van der Ende, M. Yldau and Zhao, Wei and Oldehinkel, Albertine J and Penninx, Brenda W. J. H and van der Harst, Pim and Van Vliet-Ostaptchouk, Jana V and Wang, Ya X and Lifelines Cohort Study and Lund University and et al and EpiHealth: Epidemiology for Health and Genetic and Molecular Epidemiology and Genetisk och molekylär epidemiologi and Lunds universitet and EXODIAB: Excellence in Diabetes Research in Sweden
Nature Communications, ISSN 2041-1723, 01/2019, Volume 10, Issue 1, p. 376
Many genetic loci affect circulating lipid levels, but it remains unknown whether lifestyle factors, such as physical activity, modify these genetic effects.... 
INDIVIDUALS | METAANALYSIS | CARBOXYLASE | SNP | WIDE ASSOCIATION | REVEAL | EXERCISE | Lipids - genetics | Microtubule-Associated Proteins - genetics | Cholesterol - blood | Humans | Middle Aged | Asian Continental Ancestry Group - genetics | Genetic Loci - genetics | Male | Young Adult | Exercise | Lipids - blood | Aged, 80 and over | Brazil | Adult | Cholesterol, LDL - blood | Female | Lipid Metabolism - genetics | African Continental Ancestry Group - genetics | European Continental Ancestry Group - genetics | Genome-Wide Association Study | Hispanic Americans - genetics | Membrane Proteins - genetics | Genotype | Transcription Factors - genetics | Cholesterol, HDL - genetics | Nerve Tissue Proteins - genetics | Muscle Proteins - genetics | Cholesterol, LDL - genetics | LIM-Homeodomain Proteins - genetics | Adolescent | Triglycerides - blood | Cholesterol, HDL - blood | Aged | Triglycerides - genetics | Calcium-Binding Proteins - genetics | Kardiologi | Medicinsk genetik | Basic Medicine | Medical Genetics | Clinical Medicine | Cardiac and Cardiovascular Systems | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Klinisk medicin
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