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Journal of Biological Chemistry, ISSN 0021-9258, 10/2015, Volume 290, Issue 42, pp. 25609 - 25619
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 06/2019, Volume 27, Issue 11, pp. 2192 - 2200
During our continued search for strong skin whitening agents over the past ten years, we have investigated the efficacies of many tyrosinase inhibitors... 
Perkin reaction | B16F10 melanoma cells | Inhibitor | Skin whitening | Tyrosinase | 2,3-Diphenylacrylic acid | DESIGN | CHEMISTRY, MEDICINAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | MELANIN | INHIBITORS | PIGMENTATION | MELANOCYTES
Journal Article
Brain Research, ISSN 0006-8993, 02/2019, Volume 1704, pp. 47 - 58
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors and are considered promising therapeutic targets in several neurodegenerative... 
Neuroinflammation | PPAR α/γ dual agonist | MPTP | MHY908 | Parkinson’s disease
Journal Article
Brain Research, ISSN 0006-8993, 02/2019, Volume 1704, p. 47
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors and are considered promising therapeutic targets in several neurodegenerative... 
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 11/2018, Volume 26, Issue 21, pp. 5672 - 5681
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 09/2019, Volume 27, Issue 17, pp. 3929 - 3937
Journal Article
The journals of gerontology. Series A, Biological sciences and medical sciences, ISSN 1079-5006, 05/2019
Age-associated renal fibrosis is commonly observed, with a decline in renal function during aging. Although peroxisome proliferator-activated receptors α/β... 
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 01/2019, Volume 161, p. 78
Of the three enzymes that regulate the biosynthesis of melanin, tyrosinase and its related proteins TYRP-1 and TYRP-2, tyrosinase is the most important because... 
Biological products | Melanoma | Physiological aspects | Amides | Skin | Intermedin | Acetic acid | Free radicals (Chemistry)
Journal Article
Brain Research, ISSN 0006-8993, 02/2019, Volume 1704, pp. 47 - 58
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors and are considered promising therapeutic targets in several neurodegenerative... 
Neuroinflammation | Parkinson's disease | PPAR α/γ dual agonist | MPTP | MHY908 | GAMMA | PPAR alpha/gamma dual agonist | ALPHA ACTIVATION | INFLAMMATORY RESPONSES | PROLIFERATOR-ACTIVATED RECEPTORS | ALZHEIMERS-DISEASE | NEUROSCIENCES | PIOGLITAZONE | INHIBITION | MOUSE MODEL | THERAPEUTIC TARGET | EXPRESSION
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 10/2019, Volume 180, pp. 86 - 98
The aim of this study was to design and synthesize COX-1/COX-2 balanced inhibitors incorporating the structural motifs of anti-inflammatory ascidian... 
COX-1/COX-2 | Anti-Inflammatory | Balanced inhibition | Indole | NF-κB pathway | Ascidian metabolite | HYDRAZONES | OXIDATIVE STRESS | CHEMISTRY, MEDICINAL | CYCLOOXYGENASE-2 | NF-kappa B pathway | ANALOGS | RISK | GASTRIC DAMAGE | BIOLOGICAL EVALUATION | NITRIC-OXIDE | INDOLE SCHIFF-BASES | DERIVATIVES
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 09/2018, Volume 157, pp. 1192 - 1201
In a previous study, we synthesized endocyclic enone jasmonate derivatives that function as anti-inflammatory and PPAR-γ-activating entities by using key... 
15-Deoxy-Δ | , | Prostaglandin J | PPAR-γ ligand | Algal metabolites | Exocyclic enone
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 08/2018, Volume 26, Issue 14, p. 3882
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1016/j.bmc.2018.05.047 Thirteen... 
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 09/2018, Volume 157, p. 1192
In a previous study, we synthesized endocyclic enone jasmonate derivatives that function as anti-inflammatory and PPAR-[gamma]-activating entities by using key... 
Prostaglandins | Metabolites | Luciferase | Liver | Enantiomers
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 09/2018, Volume 157, pp. 1192 - 1201
In a previous study, we synthesized endocyclic enone jasmonate derivatives that function as anti-inflammatory and PPAR-γ-activating entities by using key... 
15-Deoxy-Δ12, 14-Prostaglandin J2 | PPAR-γ ligand | Exocyclic enone | Algal metabolites
Journal Article
Bioorganic Chemistry, ISSN 0045-2068, 06/2019, Volume 87, pp. 43 - 55
Abnormal melanogenesis results in excessive production of melanin, leading to pigmentation disorders. As a key and rate-limiting enzyme for melanogenesis,... 
Docking | B10F16 melanoma cells | Tyrosinase inhibitor | Anti-melanogenic | Cinnamamide | Melanin | DESIGN | ACID | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOWN-REGULATION | CHEMISTRY, ORGANIC | DEPIGMENTING ACTION | MELANOGENESIS | IN-VITRO | ARBUTIN | DERIVATIVES | Enzymes | Medical colleges | Free radicals (Chemistry) | Analysis | Melanoma
Journal Article
Drug Design, Development and Therapy, ISSN 1177-8881, 03/2017, Volume 11, pp. 827 - 839
Journal Article
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