X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
phenothiazines (31) 31
azaphenothiazines (23) 23
index medicus (19) 19
anticancer activity (15) 15
humans (15) 15
chemistry, medicinal (14) 14
derivatives (13) 13
phenothiazines - chemistry (13) 13
phenothiazines - pharmacology (13) 13
animals (12) 12
molecular structure (12) 12
newly synthesized azaphenothiazines (12) 12
antineoplastic agents - pharmacology (11) 11
mice (11) 11
structure-activity relationship (11) 11
analysis (9) 9
antineoplastic agents - chemistry (9) 9
biochemistry & molecular biology (9) 9
lipophilicity (9) 9
apoptosis (8) 8
azinyl sulfides (8) 8
chemistry, analytical (8) 8
organic chemistry (8) 8
phenothiazines - chemical synthesis (8) 8
biochemical research methods (7) 7
cell line, tumor (7) 7
cell proliferation - drug effects (7) 7
dipyridothiazines (7) 7
antiproliferative activity (6) 6
cancer (6) 6
chemistry (6) 6
immunological-properties (6) 6
pharmacology & pharmacy (6) 6
phenothiazine (6) 6
thiazine ring formation (6) 6
anti-bacterial agents - pharmacology (5) 5
cell biology (5) 5
chemistry, organic (5) 5
dose-response relationship, drug (5) 5
drug screening assays, antitumor (5) 5
female (5) 5
inhibitors (5) 5
pyridine (5) 5
system (5) 5
thin-layer-chromatography (5) 5
2,7-diazaphenothiazines (4) 4
2d nmr spectra (4) 4
anti-bacterial agents - chemistry (4) 4
antineoplastic agents - chemical synthesis (4) 4
biochemistry, general (4) 4
cells (4) 4
chemistry, multidisciplinary (4) 4
congeneric classes (4) 4
double smiles rearrangement (4) 4
heterocyclic compounds (4) 4
leukocytes, mononuclear - drug effects (4) 4
log-p (4) 4
molecular lipophilicity (4) 4
nitrogen (4) 4
original research (4) 4
parameters (4) 4
phenothiazine derivatives (4) 4
quinobenzothiazines (4) 4
quinoline (4) 4
sulfides (4) 4
acetone (3) 3
alkaloids (3) 3
anti-inflammatory activity (3) 3
antibacterial activity (3) 3
anticancer (3) 3
anticancer properties (3) 3
antipsychotic agents - chemistry (3) 3
antipsychotic agents - pharmacology (3) 3
apoptosis - drug effects (3) 3
azaphenothiazine (3) 3
bacteria - drug effects (3) 3
biomedicine (3) 3
calibration (3) 3
care and treatment (3) 3
chemotherapy (3) 3
chromatography (3) 3
correlation analysis (3) 3
descriptors (3) 3
diquinothiazines (3) 3
drugs (3) 3
gene expressions (3) 3
human necessities (3) 3
hygiene (3) 3
immunology (3) 3
immunosuppression (3) 3
inhibition (3) 3
leukemia (3) 3
medical or veterinary science (3) 3
metallurgy (3) 3
mitogens (3) 3
ovarian cancer (3) 3
partition-coefficients (3) 3
pharmacology, toxicology and pharmaceutics (3) 3
pharmacology/toxicology (3) 3
pharmacy (3) 3
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal of Molecular Structure, ISSN 0022-2860, 11/2019, p. 127501
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 2011, Volume 46, Issue 8, pp. 3179 - 3189
This review summarizes recent medicinal chemistry investigations and in search for new phenothiazines of promising biological activities. New phenothiazine... 
Multi-drug resistance | Antifungal | Antibacterial | Azaphenothiazines | Anticancer | Phenothiazines | CHEMISTRY, MEDICINAL | MUSTARD TYPE PHENOTHIAZINES | SULFONE DERIVATIVES | ANTITUMOR-ACTIVITY | ANTICANCER ACTIVITY | ANTIMICROBIAL ACTIVITIES | RIBOFURANOSIDES | N-ACYLPHENOTHIAZINES | ANTITUBERCULAR ACTIVITY | INHIBITORS | MULTIDRUG-RESISTANCE | Analgesics - pharmacology | Drug Resistance, Multiple | Humans | Bacteria - drug effects | Cell Membrane Permeability | Trypanocidal Agents - chemistry | Antifungal Agents - chemistry | Structure-Activity Relationship | Anticonvulsants - pharmacology | Antiviral Agents - chemistry | Phenothiazines - pharmacology | Anti-Bacterial Agents - chemistry | Antineoplastic Agents - pharmacology | Immunosuppressive Agents - pharmacology | Antifungal Agents - pharmacology | Rabbits | Antiviral Agents - pharmacology | Anti-Inflammatory Agents - pharmacology | Solubility | Rats | Viruses - drug effects | Antineoplastic Agents - chemistry | Antimalarials - pharmacology | Animals | Anti-Inflammatory Agents - chemistry | Antipsychotic Agents - chemistry | Phenothiazines - chemistry | Trypanocidal Agents - pharmacology | Analgesics - chemistry | Anticonvulsants - chemistry | Antimalarials - chemistry | Hydrophobic and Hydrophilic Interactions | Anti-Bacterial Agents - pharmacology | Mice | Antipsychotic Agents - pharmacology | Immunosuppressive Agents - chemistry
Journal Article
Molecules, ISSN 1420-3049, 01/2019, Volume 24, Issue 2, p. 267
New 10-substituted derivatives of 3,6-diazaphenothiazine, containing the triple bond linker terminated with tertiary cyclic and acyclic amine groups, were... 
BAX/BCL-2 ratio | CDKN1A | Dipyridothiazines | Antiproliferative activity | Phenothiazines | Dialkylaminoalkynyl substituents | TP53 | Apoptosis | CELLS | dialkylaminoalkynyl substituents | BIOCHEMISTRY & MOLECULAR BIOLOGY | AZAPHENOTHIAZINES | apoptosis | phenothiazines | CHEMISTRY, MULTIDISCIPLINARY | antiproliferative activity | dipyridothiazines | H3
Journal Article
Medicinal Chemistry Research, ISSN 1054-2523, 11/2016, Volume 25, Issue 11, pp. 2425 - 2433
Journal Article
Journal of Enzyme Inhibition and Medicinal Chemistry, ISSN 1475-6366, 01/2019, Volume 34, Issue 1, pp. 1298 - 1306
10H-1,9-diazaphenothiazine was obtained in the sulphurisation reaction of diphenylamine with elemental sulphur and transformed into new 10-substituted... 
gene expressions | anticancer activity | Phenothiazines | 2D NMR spectra | dipyridothiazines | DOUBLE SMILES REARRANGEMENT | APOPTOSIS | CHEMISTRY, MEDICINAL | PYRIDINE CHEMISTRY | BIOCHEMISTRY & MOLECULAR BIOLOGY | AZAPHENOTHIAZINES | BINDING
Journal Article
Journal of Chromatographic Science, ISSN 0021-9665, 04/2018, Volume 56, Issue 4, pp. 376 - 381
Abstract The lipophilicity of new two series of anticancer active 10-substituted 1,6- and 3,6-diazaphenothiazines has been investigated using reversed-phase... 
CHEMISTRY, ANALYTICAL | LOG-P | QUINOBENZOTHIAZINES | THIN-LAYER-CHROMATOGRAPHY | MOLECULAR LIPOPHILICITY | BIOLOGICAL-ACTIVITY | DRUG DISCOVERY | PHENOTHIAZINES | BIOCHEMICAL RESEARCH METHODS | PARAMETERS | 2,7-DIAZAPHENOTHIAZINES | DERIVATIVES
Journal Article
Medicinal Chemistry Research, ISSN 1054-2523, 4/2015, Volume 24, Issue 4, pp. 1408 - 1418
A new type of tricyclic azaphenothiazines—1,8-diazaphenothiazines—was obtained in the reaction of 2,3- and 3,4-disubstituted pyridines. The reaction ran as the... 
Biochemistry, general | Biomedicine | Antiproliferative activity | Thiazine ring formation | Phenothiazines | Anticancer activity | Pharmacology/Toxicology | Diazaphenothiazines | Cell Biology | SYSTEM | CHEMISTRY, MEDICINAL | SMILES REARRANGEMENT | CANCER | Colon cancer | Pyridine | Medical examination | Analysis | Leukemia | Resveratrol | Blood | Phenothiazine | Original Research
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 09/2017, Volume 138, pp. 774 - 806
Journal Article
International Immunopharmacology, ISSN 1567-5769, 11/2016, Volume 40, p. 265
Several, previously selected azaphenothiazines, as strongly antiproliferative agents in in vitro models, were subjected to evaluation for their potential... 
Drugs | Ovalbumin | Animal models | Hypersensitivity (delayed) | Hypersensitivity | Pharmacology | Feet | Side effects | Immunosuppression | Rodents | Mice | Carrageenan | In vitro methods and tests | Immune system
Journal Article
Journal of Molecular Structure, ISSN 0022-2860, 04/2017, Volume 1133, pp. 398 - 404
Phenothiazines are reported to exhibit very promising anticancer, antibacterial, antifungal, anti-inflammatory activities, reversal of multidrug resistance and... 
Dipyrido-1,4-thiazines | Double Smiles rearrangement | X-ray analysis | Thiazine ring formation | Phenothiazines | 2D NMR spectra | SYSTEM | CRYSTAL-STRUCTURE | NEWLY SYNTHESIZED AZAPHENOTHIAZINES | CHEMISTRY, PHYSICAL | 2,7-DIAZAPHENOTHIAZINES | SULFIDE | ANTICANCER ACTIVITY | C18H14N2OS | DERIVATIVES | Alkaloids | Sulfides | Drug resistance in microorganisms | Pyridine | Analysis
Journal Article