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1. Full Text Long-term mortality and quality of life after septic shock: a follow-up observational study
by Nesseler, Nicolas and Defontaine, Anne and Launey, Yoann and Morcet, Jeff and Mallédant, Yannick and Seguin, Philippe
Intensive Care Medicine, ISSN 0342-4642, 5/2013, Volume 39, Issue 5, pp. 881 - 888
In septic shock, short-term outcomes are frequently reported, while long-term outcomes are not. The aim of this study was to evaluate mortality and... 
Pediatrics | Pain Medicine | Emergency Medicine | Pneumology/Respiratory System | Medicine & Public Health | Outcome | Mortality | Short-form 36 | Intensive / Critical Care Medicine | Septic shock | Anesthesiology | Quality of life | MULTICENTER | INTENSIVE-CARE | ADMISSION | SF-36 HEALTH SURVEY | SURVEY QUESTIONNAIRE | INFECTION | SURVIVORS | EPIDEMIOLOGY | SEVERE SEPSIS | CRITICAL CARE MEDICINE | France - epidemiology | Intensive Care Units | Prospective Studies | Age Factors | Health Status Indicators | Humans | Middle Aged | Risk Factors | Hospitals, University | Logistic Models | Male | Chi-Square Distribution | Shock, Septic - mortality | Statistics, Nonparametric | Aged, 80 and over | Quality of Life | Female | Surveys and Questionnaires | Aged | Length of Stay - statistics & numerical data | Patient outcomes | Life Sciences | Human health and pathology | Surgery
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2. Full Text Reduced phenotypic expression in genetic hemochromatosis with time: Role of exposure to non-genetic modifiers
by Deugnier, Yves and Morcet, Jeff and Lainé, Fabrice and Hamdi-Roze, Houda and Bollard, Anne-Sophie and Guyader, Dominique and Moirand, Romain and Bardou-Jacquet, Edouard
Journal of Hepatology, ISSN 0168-8278, 01/2019, Volume 70, Issue 1, pp. 118 - 125
Genetic hemochromatosis is mainly related to the homozygous p.Cys282Tyr (C282Y) mutation in the gene, which causes hepcidin deficiency. Its low penetrance... 
Phenotype | Tobacco | Genotype | Evolution | Alcohol | HFE hemochromatosis | BMI | FIBROSIS | IRON-OVERLOAD | HFE | HEPCIDIN | GASTROENTEROLOGY & HEPATOLOGY | Transferrin | Body weight | Liver | Ferritin | Tobacco smoking | Arthritis | Males | Risk factors | Cofactors | Genetic screening | Genetic factors | Diagnosis | Pancreas | Hemochromatosis | Diabetes mellitus | Fatigue | Homozygotes | Cirrhosis | Fibrosis | HFE protein | Diabetes | Females | Hepcidin | Smoking
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3. Full Text Analysis of a French cohort of patients with large granular lymphocyte leukemia: a report on 229 cases
by Benoît Bareau and Jérôme Rey and Mohamed Hamidou and Jean Donadieu and Jeff Morcet and Oumedaly Reman and Nicolas Schleinitz and Olivier Tournilhac and Mikael Roussel and Thierry Fest and Thierry Lamy
Haematologica, ISSN 0390-6078, 09/2010, Volume 95, Issue 9, pp. 1534 - 1541
Background Large granular lymphocyte leukemia is a rare lymphoproliferative disorder associated with autoimmune diseases and impaired hematopoiesis. This study... 
Large granular lymphocyte leukemia | LGL leukemia | NK lymphocytosis | RHEUMATOID-ARTHRITIS | LOW-DOSE METHOTREXATE | V-BETA REPERTOIRE | PROLIFERATIONS | CLINICAL-FEATURES | large granular lymphocyte leukemia | THERAPY | NEUTROPENIA | LYMPHOPROLIFERATIVE DISEASE | DISORDER | HEMATOLOGY | CYCLOSPORINE | France - epidemiology | Humans | Middle Aged | Male | Treatment Outcome | Killer Cells, Natural - pathology | Leukemia, Large Granular Lymphocytic - diagnosis | Leukemia, Large Granular Lymphocytic - epidemiology | Lymphocytosis - diagnosis | Adult | Female | Registries | Aged | T-Lymphocytes - pathology | Leukemia, Large Granular Lymphocytic - therapy | Cohort Studies | Life Sciences | Cancer | Original
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4. Full Text Non-invasive measurement of liver iron concentration using 3-Tesla magnetic resonance imaging: validation against biopsy
by d’Assignies, Gaspard and d’Assignies, Gaspard and Paisant, Anita and Paisant, Anita and Bardou-Jacquet, Edouard and Bardou-Jacquet, Edouard and Boulic, Anne and Boulic, Anne and Bannier, Elise and Bannier, Elise and Lainé, Fabrice and Lainé, Fabrice and Ropert, Martine and Ropert, Martine and Morcet, Jeff and Morcet, Jeff and Saint-Jalmes, Hervé and Saint-Jalmes, Hervé and Gandon, Yves and Gandon, Yves
European Radiology, ISSN 0938-7994, 5/2018, Volume 28, Issue 5, pp. 2022 - 2030
To evaluate the performance and limitations of the R2* and signal intensity ratio (SIR) methods for quantifying liver iron concentration (LIC) at 3 T.A total... 
Medicine & Public Health | Diagnostic Radiology | Magnetic resonance imaging | Liver | Internal Medicine | Iron | Haemosiderosis | Interventional Radiology | Imaging / Radiology | Ultrasound | Neuroradiology | Haemochromatosis | OVERLOAD | DIAGNOSIS | 1.5 T | MRI | QUANTIFICATION | THALASSEMIA | DISEASE | NEEDLE-BIOPSY | BURDEN | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | HEMOCHROMATOSIS | Liver - pathology | Reproducibility of Results | Prospective Studies | Humans | Liver - metabolism | Middle Aged | Magnetic Resonance Imaging - methods | Male | Iron Overload - diagnostic imaging | Algorithms | Iron Overload - metabolism | Biopsy | Sensitivity and Specificity | Female | Measurement | Resveratrol | Confidence intervals | Sensitivity | Sensitivity analysis | Nuclear magnetic resonance--NMR | Mathematical analysis | Patients | Metabolic disorders | Life Sciences | Bioengineering | Imaging
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5. Full Text SAT-410-Higher spleen iron content estimated by MRIT2 signal is associated with lower insulin-resistance in patients with dysmetabolic iron overload syndrome
by Cassandra, Rayer and Anita, Paisant and Jeff, Morcet and Yves, Deugnier and Yves, Gandon and Fabrice, Laine and Bardou-Jacquet, Edouard
Journal of Hepatology, ISSN 0168-8278, 04/2019, Volume 70, Issue 1, pp. e814 - e814
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6. Full Text Acoustic radiation force impulse imaging for assessing liver fibrosis in alcoholic liver disease
by Anita Kiani Vanessa Brun Fabrice Lainé Bruno Turlin Jeff Morcet Sophie Michalak Antonia Le Gruyer Ludivine Legros Edouard Bardou-Jacquet Yves Gandon Romain Moirand
世界胃肠病学杂志：英文版, ISSN 1007-9327, 2016, Volume 22, Issue 20, pp. 4926 - 4935
AIM: To evaluate the performance of elastography by ultrasound with acoustic radiation force impulse(ARFI) in determining fibrosis stage in patients with... 
force | impulse;Fibrosis | liver | radiation | disease;Elastography;Noninvasive;Acoustic | Alcoholic | Elastography | Noninvasive | Acoustic radiation force impulse | Fibrosis | Alcoholic liver disease | Non-invasive | ARFI ELASTOGRAPHY | FOOD-INTAKE | CHRONIC HEPATITIS-C | SAMPLING VARIABILITY | BIOPSY | STIFFNESS MEASUREMENT | TRANSIENT ELASTOGRAPHY | VALUES | INDEX | GASTROENTEROLOGY & HEPATOLOGY | NONINVASIVE ASSESSMENT | Liver Cirrhosis, Alcoholic - diagnostic imaging | Severity of Illness Index | Predictive Value of Tests | Liver - pathology | Reproducibility of Results | Prospective Studies | Liver Cirrhosis, Alcoholic - therapy | Area Under Curve | Liver Cirrhosis, Alcoholic - pathology | Humans | Middle Aged | Male | Biopsy | Liver - diagnostic imaging | Adult | Female | ROC Curve | Elasticity Imaging Techniques | Life Sciences | Prospective Study
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7. Full Text Determination of capillary hemoglobin levels using the HemoCue system in intensive care patients
by Seguin, Philippe, MD, PhD and Kleiber, Agathe, MD and Chanavaz, Charles, MD and Morcet, Jeff, BSc and Mallédant, Yannick, MD
Journal of Critical Care, ISSN 0883-9441, 2010, Volume 26, Issue 4, pp. 423 - 427
Abstract Purpose The study aimed to compare hemoglobin (Hb) values determined using the portable HemoCue system (HemoCue Hb 201+; HemoCue AB, Ängelholm,... 
Critical Care | Hemoglobinometer | HemoCue | Intensive care | Hemoglobin measurement | Anemia | BLOOD-LOSS | RELIABILITY | CRITICAL CARE MEDICINE | Intensive Care Units | Prospective Studies | Point-of-Care Systems | Humans | Middle Aged | Critical Illness | Female | Hemoglobinometry - instrumentation | Male | Capillaries | Hemoglobins - analysis | Hemoglobin | Hépatology and Gastroenterology | Hemoglobinometry | Life Sciences | Human health and pathology | Hemoglobins
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8. Full Text Decreased iron burden in overweight C282Y homozygous women: Putative role of increased hepcidin production
by Desgrippes, Romain and Lainé, Fabrice and Morcet, Jeff and Perrin, Michèle and Manet, Ghislain and Jezequel, Caroline and Bardou‐Jacquet, Edouard and Ropert, Martine and Deugnier, Yves
Hepatology, ISSN 0270-9139, 05/2013, Volume 57, Issue 5, pp. 1784 - 1792
An excess of visceral adipose tissue could be involved as a modulator of the penetrance of HFE hemochromatosis since fat mass is associated with overexpression... 
OVERLOAD | HFE HEMOCHROMATOSIS | SUBCUTANEOUS ADIPOSE-TISSUE | GENE | INSULIN-RESISTANCE | IN-VIVO | LIVER | HEREDITARY HEMOCHROMATOSIS | OBESE | GASTROENTEROLOGY & HEPATOLOGY | PHENOTYPIC-EXPRESSION | Multivariate Analysis | Hemochromatosis Protein | Humans | Middle Aged | Hemochromatosis - blood | Male | Case-Control Studies | Ferritins - blood | Overweight - epidemiology | Hepcidins | Insulin Resistance - physiology | Adult | Female | Retrospective Studies | Antimicrobial Cationic Peptides - blood | Hemochromatosis - genetics | Iron - blood | Body Mass Index | Comorbidity | Membrane Proteins - genetics | Phlebotomy | Histocompatibility Antigens Class I - genetics | Homozygote | Overweight - blood | Hemochromatosis - epidemiology | Transferrin - metabolism | Cohort Studies | Confidence intervals | Body mass index | Iron | Multivariate analysis | Hepatology | Life Sciences | Human health and pathology | Hépatology and Gastroenterology
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9. Full Text Long‐term results of combined liver‐kidney transplantation for primary hyperoxaluria type 1: The French Experience
by Compagnon, Philippe and Metzler, Philippe and Samuel, Didier and Camus, Christophe and Niaudet, Patrick and Durrbach, Antoine and Lang, Philippe and Azoulay, Daniel and Duvoux, Christophe and Bayle, Francois and Rivalan, Joseph and Merville, Pierre and Pascal, Gerard and Thervet, Eric and Bensman, Albert and Rostaing, Lionel and Deschenes, Georges and Morcet, Jeff and Feray, Cyrille and Boudjema, Karim
Liver Transplantation, ISSN 1527-6465, 12/2014, Volume 20, Issue 12, pp. 1475 - 1485
Primary hyperoxaluria type 1 (PH1) is a hepatic metabolic defect leading to end‐stage renal failure. The posttransplant recurrence of kidney disease can... 
SURGERY | OXALATE DYNAMICS | COMBINED LIVER/KIDNEY TRANSPLANTATION | PERITONEAL-DIALYSIS | CHILDREN | TRANSPLANTATION | CROSS-MATCH | PRIMARY OXALOSIS | LIVING DONOR | GRAFT-SURVIVAL | GASTROENTEROLOGY & HEPATOLOGY | SEQUENTIAL LIVER | CHRONIC-RENAL-FAILURE | Hyperoxaluria, Primary - surgery | Reoperation | Liver Transplantation | Kidney Failure, Chronic - surgery | Follow-Up Studies | Hyperoxaluria, Primary - mortality | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Child, Preschool | Graft Survival | Infant | Male | Treatment Outcome | Hyperoxaluria - complications | Kidney Transplantation | Young Adult | Hyperoxaluria - surgery | Adolescent | Adult | Female | France | Child
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10. Full Text Pulse oximetry and high-dose vasopressors: a comparison between forehead reflectance and finger transmission sensors
by Nesseler, Nicolas and Frénel, Jean-Vincent and Launey, Yoann and Morcet, Jeff and Mallédant, Yannick and Seguin, Philippe
Intensive Care Medicine, ISSN 0342-4642, 10/2012, Volume 38, Issue 10, pp. 1718 - 1722
Pulse oximetry (SpO2) measured at finger site via transmission mode may fail in situations of hypoperfusion. Forehead sensors using reflectance technology... 
Shock | Pediatrics | Emergency Medicine | Intensive / Critical Care Medicine | Pain Medicine | Reflectance technology | Pneumology/Respiratory System | Medicine & Public Health | Finger transmission sensor | Forehead reflectance sensor | Anesthesiology | Pulse oximetry | Vasopressor therapy | PERIPHERAL PERFUSION | INTENSIVE-CARE-UNIT | ACCURACY | CRITICAL CARE MEDICINE | Intensive Care Units | Vasoconstrictor Agents - administration & dosage | Prospective Studies | Humans | Middle Aged | Forehead - blood supply | Shock - physiopathology | Critical Illness | Epinephrine - administration & dosage | Norepinephrine - administration & dosage | Pulse - instrumentation | Shock - drug therapy | Oximetry - instrumentation | Fingers - blood supply | Aged, 80 and over | Adult | Aged | Epinephrine | Hépatology and Gastroenterology | Oximetry | Pulse | Life Sciences | Human health and pathology | Forehead | Vasoconstrictor Agents | Fingers | Norepinephrine
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11. Full Text Management of gastric neuro-endocrine tumours in a large French national cohort (GTE)
by Manfredi, Sylvain and Walter, Thomas and Baudin, Eric and Coriat, Romain and Ruszniewski, Philippe and Lecomte, Thierry and Laurenty, Anne-Pascale and Goichot, Bernard and Rohmer, Vincent and Roquin, Guillaume and Cojocarasu, Oana-Zvetlana and Lombard-Bohas, Catherine and Lepage, Côme and Morcet, Jeff and Cadiot, Guillaume
Endocrine, ISSN 1355-008X, 9/2017, Volume 57, Issue 3, pp. 504 - 511
Gastric neuro-endocrine tumours are rare. European guidelines for the management of neuro-endocrine tumours have been published in 2012. The aim of our survey... 
Treatment | Medicine & Public Health | Cohort | Science, Humanities and Social Sciences, multidisciplinary | Internal Medicine | Gastric neuro-endocrine tumour | Diabetes | Survival | Endocrinology | POPULATION | SOMATOSTATIN ANALOGS | MULTICENTER | PROGNOSIS | GUIDELINES | DIGESTIVE ENDOCRINE TUMORS | CARCINOID-TUMORS | ENDOCRINOLOGY & METABOLISM | TERM-FOLLOW-UP | TYPE-1 | STOMACH | Prospective Studies | Follow-Up Studies | Humans | Middle Aged | Male | Stomach Neoplasms - pathology | Practice Patterns, Physicians | Young Adult | Neoplasm Grading | Aged, 80 and over | Adult | Female | Registries | Pancreatic Neoplasms - mortality | France | Child | Neuroendocrine Tumors - pathology | Intestinal Neoplasms - mortality | Pancreatic Neoplasms - pathology | Stomach Neoplasms - therapy | Combined Modality Therapy | Intestinal Neoplasms - pathology | Intestinal Neoplasms - therapy | Adolescent | Neuroendocrine Tumors - mortality | Survival Analysis | Aged | Neuroendocrine Tumors - therapy | Neoplasm Staging | Stomach Neoplasms - mortality | Health Care Surveys | Cohort Studies | Pancreatic Neoplasms - therapy | Practice Guidelines as Topic | Endocrine gland diseases | Chemotherapy | Usage | Care and treatment | Diagnosis | Cancer
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12. Full Text Curcuma decreases serum hepcidin levels in healthy volunteers: a placebo‐controlled, randomized, double‐blind, cross‐over study
by Lainé, Fabrice and Laviolle, Bruno and Bardou‐Jacquet, Edouard and Fatih, Nadia and Jezequel, Caroline and Collet, Nicolas and Ropert, Martine and Morcet, Jeff and Hamon, Catherine and Reymann, Jean‐Michel and Loréal, Olivier
Fundamental & Clinical Pharmacology, ISSN 0767-3981, 10/2017, Volume 31, Issue 5, pp. 567 - 573
Hepcidin, secreted by hepatocytes, controls iron metabolism by limiting iron egress in plasma. Hepcidin is upregulated during inflammation through the... 
iron metabolism | hepcidin | curcuma | healthy volunteers | FERROPORTIN | STAT3 | IRON OVERLOAD | REGULATOR | CHRONIC DISEASE | METABOLISM | INFLAMMATION | PHARMACOLOGY & PHARMACY | MICE | ANEMIA | EXPRESSION | Double-Blind Method | Administration, Oral | Humans | Hepcidins - blood | Male | Biomarkers - blood | Healthy Volunteers | Blood Glucose - drug effects | Cross-Over Studies | Plant Extracts - administration & dosage | Young Adult | Pilot Projects | Adult | Curcuma | Blood Glucose - metabolism | Medicine, Experimental | Medical research | Ferritin | Transferrin | Transcription | Anemia | Saturation | Stat3 protein | Iron | Egress | In vitro testing | Bioavailability | Metabolism | Randomization | Synthesis | Hepatocytes | Curcumin | Hepcidin | Life Sciences | Pharmacology | Pharmaceutical sciences
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13. Full Text Worse Outcomes of Patients With HFE Hemochromatosis With Persistent Increases in Transferrin Saturation During Maintenance Therapy
by Bardou-Jacquet, Edouard and Lainé, Fabrice and Guggenbuhl, Pascal and Morcet, Jeff and Jézéquel, Caroline and Guyader, Dominique and Moirand, Romain and Deugnier, Yves
Clinical Gastroenterology and Hepatology, ISSN 1542-3565, 2017, Volume 15, Issue 10, pp. 1620 - 1627
Background & Aims Even if patients with hemochromatosis maintain low serum levels of ferritin, they still have an increased risk of general and joint symptoms,... 
Gastroenterology and Hepatology | Arthropathy | Iron Regulation | Treatment | Hepcidin Deficiency | DIAGNOSIS | HEPCIDIN | MECHANISMS | HEREDITARY HEMOCHROMATOSIS | BOUND IRON | ARTHRITIS | GENETIC HEMOCHROMATOSIS | GUIDELINE | GASTROENTEROLOGY & HEPATOLOGY | ASSOCIATION | EXPRESSION | Tertiary Care Centers | Humans | Middle Aged | Ferritins - analysis | Joints - pathology | Male | Treatment Outcome | Hemochromatosis - pathology | Transferrin - analysis | Young Adult | Time Factors | Hemochromatosis Protein - genetics | Adolescent | Aged, 80 and over | Adult | Female | Aged | France | Longitudinal Studies | Hemochromatosis - genetics | Serum - chemistry | Care and treatment | Transferrin | Hemochromatosis | Patient outcomes | Ferritin | Medical research | Analysis | Medicine, Experimental | Life Sciences | Human health and pathology | Hépatology and Gastroenterology
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14. Full Text Reduced phenotypic expression in genetic hemochromatosis with time role of exposure to nongenetic modifiers
by Deugnier, Yves and Morcet, Jeff and Lainé, Fabrice and Hamdi-Rozé, Houda and Bollard, Anne-Sophie and Guyader, Dominique and Moirand, Romain and Bardou-Jacquet, Edouard
Journal of Hepatology, ISSN 0168-8278, 2018, Volume 70, Issue 1, pp. 118 - 125
Genetic hemochromatosis is mainly related to the homozygous genotype for the HFE p.Cys282Tyr (C282Y) mutation leading to hepcidin deficiency. Its low... 
Life Sciences
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15. Full Text Early effects of erythropoietin on serum hepcidin and serum iron bioavailability in healthy volunteers
by Lainé, Fabrice and Lainé, Fabrice and Laviolle, Bruno and Laviolle, Bruno and Ropert, Martine and Ropert, Martine and Bouguen, Guillaume and Bouguen, Guillaume and Morcet, Jeff and Morcet, Jeff and Hamon, Catherine and Hamon, Catherine and Massart, Catherine and Massart, Catherine and Westermann, Mark and Westermann, Mark and Deugnier, Yves and Deugnier, Yves and Loréal, Olivier and Loréal, Olivier
European Journal of Applied Physiology, ISSN 1439-6319, 4/2012, Volume 112, Issue 4, pp. 1391 - 1397
Hepcidin regulates plasma iron bioavailability and subsequently iron availability for erythropoiesis. rHuEPO has been reported to decrease hepcidin expression... 
Biomedicine | Healthy volunteers | Human Physiology | Erythropoietin | Sports Medicine | Occupational Medicine/Industrial Medicine | Iron | Hepcidin | Pharmacokinetic | OVERLOAD | SPORT SCIENCES | PHYSIOLOGY | ALTERED ERYTHROPOIESIS | UTILIZING MARKERS | RETICULOCYTE PRODUCTION-RATE | C/EBP-ALPHA | METABOLISM | ABUSE | ANTIMICROBIAL PEPTIDE | ABSORPTION | EXPRESSION | Injections, Intravenous | Humans | Iron-Binding Proteins - blood | Biological Availability | Male | Young Adult | Ferritins - blood | Time Factors | Hepcidins | Placebos | Adult | Substance Abuse Detection | Antimicrobial Cationic Peptides - blood | France | Iron - blood | Erythropoietin - administration & dosage | Double-Blind Method | Enzyme-Linked Immunosorbent Assay | Receptors, Cell Surface - blood | Hematinics - administration & dosage | Recombinant Proteins - administration & dosage | Cross-Over Studies | Growth Differentiation Factor 15 - blood | Transferrin - metabolism | Doping in Sports | Usage | Transferrin | Analysis | Glycoproteins | Enzyme-linked immunosorbent assay | Receptors, Cell Surface | Recombinant Proteins | Growth Differentiation Factor 15 | Life Sciences | Iron-Binding Proteins | Hematinics | Hépatology and Gastroenterology | Antimicrobial Cationic Peptides | Human health and pathology | Ferritins
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