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by Rohde, Luis Eduardo Paim and Montera, Marcelo Westerlund and Bocchi, Edimar Alcides and Bocchi, Edimar Alcides and Clausell, Nadine Oliveira and Albuquerque, Denilson Campos de and de Albuquerque, Denilson Campos and Rassi, Salvador and Colafranceschi, Alexandre Siciliano and Freitas Junior, Aguinaldo Figueiredo de and de Freitas Junior, Aguinaldo Figueiredo and Ferraz, Almir Sergio and Biolo, Andreia and Barretto, Antonio C. Pereira and Barretto, Antonio C Pereira and Ribeiro, Antonio Luiz Pinho and Ribeiro, Antonio Luiz Pinho and Polanczyk, Carisi Anne and Gualandro, Danielle Menosi and Gualandro, Danielle Menosi and Almeida, Dirceu Rodrigues and Silva, Eneida Rejane Rabelo da and da Silva, Eneida Rejane Rabelo and Figueiredo, Estêvão Lanna and Figueiredo, Estêvão Lanna and Mesquita, Evandro Tinoco and Marcondes-Braga, Fabiana G and Marcondes-Braga, Fabiana G and Cruz, Fátima das Dores da and da Cruz, Fátima das Dores and Ramires, Felix José Alvarez and Ramires, Felix José Alvarez and Atik, Fernando Antibas and Bacal, Fernando and Bacal, Fernando and Souza, Germano Emilio Conceição and Souza, Germano Emilio Conceição and Almeida Junior, Gustavo Luiz Gouvêa de and de Almeida Junior, Gustavo Luiz Gouvêa and Ribeiro, Gustavo Calado de Aguiar and Ribeiro, Gustavo Calado de Aguiar and Villacorta Junior, Humberto and Vieira, Jefferson Luís and Souza Neto, João David de and Neto, João David de Souza and Rossi Neto, João Manoel and Neto, João Manoel Rossi and Neto, Jose Albuquerque de Figueiredo and Figueiredo Neto, Jose Albuquerque de and Moura, Lidia Ana Zytynsky and Moura, Lidia Ana Zytynsky and Goldraich, Livia Adams and Beck-da-Silva, Luis and Danzmann, Luiz Claudio and Danzmann, Luiz Claudio and Canesin, Manoel Fernandes and Bittencourt, Marcelo Imbroinise and Garcia, Marcelo Iorio and Bonatto, Marcely Gimenes and Bonatto, Marcely Gimenes and Simões, Marcus Vinícius and Moreira, Maria da Consolação Vieira and Moreira, Maria da Consolação Vieira and da Silva, Miguel Morita Fernandes and Silva, Miguel Morita Fernandes da and de Olivera Junior, Mucio Tavares and Olivera Junior, Mucio Tavares de and Silvestre, Odilson Marcos and Schwartzmann, Pedro Vellosa and Bestetti, Reinaldo Bulgarelli and Rocha, Ricardo Mourilhe and Simões, Ricardo and Simões, Ricardo and Pereira, Sabrina Bernardez and Mangini, Sandrigo and Mangini, Sandrigo and Alves, Sílvia Marinho Martins and Alves, Sílvia Marinho Martins and Ferreira, Silvia Moreira Ayub and Ferreira, Silvia Moreira Ayub and Issa, Victor Sarli and Issa, Victor Sarli and Barzilai, Vitor Salvatore and Martins, Wolney de Andrade
Arquivos brasileiros de cardiologia, ISSN 0066-782X, 09/2018, Volume 111, Issue 3, pp. 436 - 539
Journal Article
02/2020
Un compuesto de la siguiente fórmula (II)**Fórmula** en donde: X es un átomo de nitrógeno o CH; Y es un átomo de nitrógeno o CH; Z es un átomo de nitrógeno o... 
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | METALLURGY | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
07/2019
The present invention relates to amide derivatives which have blocking activities of voltage gated sodium channels as the TTX-S channels, and which are useful in the treatment or prevention of... 
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | METALLURGY | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
10/2018
The present invention relates to pyrrolopyridinone derivatives which have blocking activities of voltage gated sodium channels as the TTX-S channels, and which are useful in the treatment or... 
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | METALLURGY | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
01/2019
The present invention relates to pyrazolopyridine derivatives which have blocking activities of voltage gated sodium channels as the TTX-S channels, and which are useful in the treatment or prevention... 
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | METALLURGY | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
12/2017
...-carbocíclico o mono o bi-heterocíclico que puede contener de 0 a 4 heteroátomos seleccionados entre O, N y S; B es -NR2- o -(C>=O)-; C es -(C>=O)- o -NR2... 
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | METALLURGY | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
05/2017
Un compuesto de la siguiente fórmula (II)**Fórmula** en la que R1 se selecciona independientemente entre el grupo que consiste en -CF3, -CHF2, -OCF3, - OCHF2,... 
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | METALLURGY | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
09/2015
The present invention relates to pyrazolopyridine derivatives which have blocking activities of voltage gated sodium channels as the TTX-S channels, and which are useful in the treatment or prevention... 
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | METALLURGY | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
11/2014
The present invention relates to pyrrolopyridinone derivatives which have blocking activities of voltage gated sodium channels as the TTX-S channels, and which are useful in the treatment or... 
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | METALLURGY | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
11/2014
The present invention relates to amide derivatives which have blocking activities of voltage gated sodium channels as the TTX-S channels, and which are useful in the treatment or prevention of... 
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | METALLURGY | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
07/2013
The present invention relates to arylamide derivatives which have blocking activities of voltage gated sodium channels as the TTX-S channels, and which are useful in the treatment or prevention of... 
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | METALLURGY | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent