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1. Full Text Different residues in the GABAA receptor benzodiazepine binding pocket mediate benzodiazepine efficacy and binding
by Morlock, Elaine V and Czajkowski, Cynthia
Molecular pharmacology, ISSN 0026-895X, 07/2011, Volume 80, Issue 1, pp. 14 - 22
Amino Acid Sequence | Benzodiazepines - pharmacology | Mutagenesis, Site-Directed | Xenopus laevis | Models, Molecular | Molecular Sequence Data | Rats | Receptors, GABA-A - chemistry | Sequence Homology, Amino Acid | Animals | Receptors, GABA-A - genetics | Receptors, GABA-A - metabolism | Benzodiazepines - metabolism | Binding Sites | Index Medicus
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2. Full Text Structural Requirements for Eszopiclone and Zolpidem Binding to the γ-Aminobutyric Acid Type-A (GABAA) Receptor Are Different
by Hanson, Susan M and Morlock, Elaine V and Satyshur, Kenneth A and Czajkowski, Cynthia
Journal of medicinal chemistry, ISSN 0022-2623, 11/2008, Volume 51, Issue 22, pp. 7243 - 7252
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Psychology. Psychoanalysis. Psychiatry | Hypnotics. Sedatives | Neurotransmitters. Neurotransmission. Receptors | Psychopharmacology | Pharmacology. Drug treatments | Biological and medical sciences | Gabaergic and benzodiazepinic system | Medical sciences | Neuropharmacology | Models, Chemical | Pyridines - chemistry | Humans | Piperazines - metabolism | Piperazines - chemistry | Structure-Activity Relationship | Receptors, GABA-A - chemistry | Eszopiclone | Azabicyclo Compounds - chemistry | Azabicyclo Compounds - metabolism | Cysteine - genetics | DNA Mutational Analysis | Computer Simulation | Cysteine - metabolism | Benzodiazepines - metabolism | Binding Sites | Cell Line | Mutagenesis, Site-Directed | Models, Molecular | GABA-A Receptor Agonists | Pyridines - metabolism | Hydrogen Bonding | Receptors, GABA-A - genetics | Benzodiazepines - chemistry | Ligands | Receptors, GABA-A - metabolism | Index Medicus
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3. Full Text Bladder cancer SNP panel predicts susceptibility and survival
by Andrew, Angeline S and Gui, Jiang and Sanderson, Arthur C and Mason, Rebecca A and Morlock, Elaine V and Schned, Alan R and Kelsey, Karl T and Marsit, Carmen J and Moore, Jason H and Karagas, Margaret R
Human genetics, ISSN 0340-6717, 6/2009, Volume 125, Issue 5, pp. 527 - 539
Human Genetics | Gene Function | Molecular Medicine | Biomedicine | Metabolic Diseases | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Classical genetics, quantitative genetics, hybrids | Human | Tumors of the urinary system | Urinary tract. Prostate gland | Urinary system involvement in other diseases. Miscellaneous | Nephrology. Urinary tract diseases | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | Genetic Predisposition to Disease | Urinary Bladder Neoplasms - mortality | Humans | Middle Aged | Risk Factors | Genotype | Male | Case-Control Studies | Urinary Bladder Neoplasms - genetics | Molecular Epidemiology | Alleles | Adult | Female | Aged | Models, Genetic | Polymorphism, Single Nucleotide | DNA, Neoplasm - genetics | Index Medicus | Original Investigation
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4. Full Text EGFR pathway polymorphisms and bladder cancer susceptibility and prognosis
by Mason, Rebecca A and Morlock, Elaine V and Karagas, Margaret R and Kelsey, Karl T and Marsit, Carmen J and Schned, Alan R and Andrew, Angeline S
Carcinogenesis (New York), ISSN 0143-3334, 7/2009, Volume 30, Issue 7, pp. 1155 - 1160
Life Sciences & Biomedicine | Oncology | Science & Technology | Tumors of the urinary system | Urinary tract. Prostate gland | Urinary system involvement in other diseases. Miscellaneous | Nephrology. Urinary tract diseases | Biological and medical sciences | Carcinogenesis, carcinogens and anticarcinogens | Medical sciences | Tumors | Receptor, Epidermal Growth Factor - genetics | Genetic Predisposition to Disease | Urinary Bladder Neoplasms - mortality | Signal Transduction | Humans | Middle Aged | Male | Risk | Case-Control Studies | Urinary Bladder Neoplasms - genetics | Aged, 80 and over | Adult | Female | Aged | Polymorphism, Single Nucleotide | Receptor, Epidermal Growth Factor - physiology | Index Medicus | Molecular Epidemiology
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5. Full Text HSD3B and Gene-Gene Interactions in a Pathway-Based Analysis of Genetic Susceptibility to Bladder Cancer
by Andrew, Angeline S and Hu, Ting and Gu, Jian and Gui, Jiang and Ye, Yuanqing and Marsit, Carmen J and Kelsey, Karl T and Schned, Alan R and Tanyos, Sam A and Pendleton, Eben M and Mason, Rebecca A and Morlock, Elaine V and Zens, Michael S and Li, Zhongze and Moore, Jason H and Wu, Xifeng and Karagas, Margaret R
PloS one, ISSN 1932-6203, 12/2012, Volume 7, Issue 12, pp. e51301 - e51301
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Genetic Predisposition to Disease - genetics | Humans | Middle Aged | Male | Multienzyme Complexes - genetics | Signal Transduction - genetics | Progesterone Reductase - genetics | Case-Control Studies | Urinary Bladder Neoplasms - genetics | Epistasis, Genetic | Urinary Bladder Neoplasms - pathology | Polymorphism, Single Nucleotide - genetics | Adult | Female | Aged | Steroid Isomerases - genetics | Telomeres | Oncology, Experimental | Genes | Physiological aspects | Genetic aspects | Disease susceptibility | Research | Bladder cancer | Apoptosis | Cancer | Dehydrogenases | Bladder | Cotton, Norris | Lymphocytes T | Epistasis | Single-nucleotide polymorphism | Hormones | Males | Medical diagnosis | DNA repair | Carcinogenesis | Signal transduction | Carcinogens | Cell activation | Cell growth | Urinary bladder | Transcription activation | Network analysis | Cell cycle | Population | Genotypes | Deoxyribonucleic acid--DNA | Enzymes | Statistical analysis | Health risks | Cell division | Immunosurveillance | Genetic diversity | Regression analysis | Metabolism | Gene expression | Biological activity | Medicine | Studies | Population (statistical) | Surveillance | 3' Untranslated regions | GATA-3 protein | Biomarkers | CD81 antigen | Health risk assessment | Females | Prostate cancer | Tumors | Index Medicus | Deoxyribonucleic acid | DNA
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6. Full Text Different Residues in the GABA(A) Receptor Benzodiazepine Binding Pocket Mediate Benzodiazepine Efficacy and Binding
by Morlock, Elaine V and Czajkowski, Cynthia
Molecular pharmacology, ISSN 0026-895X, 07/2011, Volume 80, Issue 1, pp. 14 - 22
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology
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7. Full Text Different Residues in the GABAA Receptor Benzodiazepine Binding Pocket Mediate Benzodiazepine Efficacy and BindingS
by Morlock, Elaine V and Czajkowski, Cynthia
Molecular pharmacology, ISSN 0026-895X, 7/2011, Volume 80, Issue 1, pp. 14 - 22
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8. Full Text Survival and Lifetime Costs Associated With First‐Line Bevacizumab Use in Older Patients With Metastatic Colorectal Cancer
by Shankaran, Veena and Mummy, David and Koepl, Lisel and Bansal, Aasthaa and Mirick, Dana K and Yu, Elaine and Morlock, Rob and Ogale, Sarika and Ramsey, Scott D
The oncologist (Dayton, Ohio), ISSN 1083-7159, 08/2014, Volume 19, Issue 8, pp. 892 - 899
Clinical effectiveness | Elderly | Metastatic colorectal cancer | Lifetime costs | Bevacizumab | Life Sciences & Biomedicine | Oncology | Science & Technology | Colorectal Neoplasms - epidemiology | Quality-Adjusted Life Years | Humans | Proportional Hazards Models | Antineoplastic Combined Chemotherapy Protocols | Male | Colorectal Neoplasms - economics | Antibodies, Monoclonal, Humanized - economics | Health Care Costs | Antibodies, Monoclonal, Humanized - administration & dosage | Cost-Benefit Analysis | Aged, 80 and over | Female | Aged | Colorectal Neoplasms - pathology | Index Medicus | Outcomes Research
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9. Full Text Structural requirements for eszopiclone and zolpidem binding to the GABAA receptor are different
by Hanson, Susan M and Morlock, Elaine V and Satyshur, Kenneth A and Czajkowski, Cynthia
Journal of medicinal chemistry, ISSN 0022-2623, 11/2008, Volume 51, Issue 22, pp. 7243 - 7252
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