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PLoS Genetics, ISSN 1553-7390, 11/2013, Volume 9, Issue 11, p. e1003936
  Studies in fission yeast have previously identified evolutionarily conserved shelterin and Stn1-Ten1 complexes, and established Rad3ATR/Tel1ATM-dependent... 
Phosphorylation | Yeast | Genomes | Kinases | Experiments | Recruitment | Proteins | Plasmids | Deoxyribonucleic acid | DNA | Cell cycle | Stem cells | Regulation | Mutation | Chromosomes | Telomerase
Journal Article
Pathology and Oncology Research, ISSN 1219-4956, 07/2017, Volume 23, Issue 3, pp. 551 - 564
Journal Article
PLoS Genetics, ISSN 1553-7390, 05/2017, Volume 13, Issue 5, p. e1006776
The posttranslational modifiers SUMO and ubiquitin critically regulate the DNA damage response (DDR). Important crosstalk between these modifiers at DNA... 
E3 LIGASE | FISSION YEAST | DAMAGE RESPONSE | REPAIR | TOPOISOMERASE-II | DYSFUNCTIONAL TELOMERES | GENETICS & HEREDITY | CELL-CYCLE | NUCLEAR-PORES | SUMOYLATION | SCHIZOSACCHAROMYCES-POMBE | Genomic Instability | Schizosaccharomyces pombe Proteins - genetics | Chromosomal Proteins, Non-Histone - metabolism | Small Ubiquitin-Related Modifier Proteins - metabolism | Valosin Containing Protein | Cell Cycle Proteins - metabolism | Ubiquitin-Protein Ligases - metabolism | Adenosine Triphosphatases - metabolism | DNA-Binding Proteins - genetics | Chromosomal Proteins, Non-Histone - genetics | DNA-Binding Proteins - metabolism | Schizosaccharomyces - genetics | Small Ubiquitin-Related Modifier Proteins - genetics | Schizosaccharomyces - metabolism | Telomere-Binding Proteins - genetics | Genome, Fungal | DNA Repair | Schizosaccharomyces pombe Proteins - metabolism | Cell Cycle Proteins - genetics | Sumoylation | Adenosine Triphosphatases - genetics | Telomere-Binding Proteins - metabolism | Ubiquitin-Protein Ligases - genetics | Embryonic development | Cell development (Biology) | Analysis | Genetic aspects | Research | Genetic transcription | Ubiquitin-proteasome system | Hybrids | Yeast | DNA damage | Crosstalk | Chains | Biochemistry | Genomes | Translocase | DNA repair | Fission | Defects | Genomic instability | Degradation | Proteins | SUMO protein | Cell cycle | Genetics | Lesions | Damage | Repair | Telomerase | Ubiquitin-protein ligase | Deoxyribonucleic acid--DNA | Telomere-binding protein | Stability | TRF2 protein | Aberration | Deoxyribonucleic acid | DNA
Journal Article
PLoS Genetics, ISSN 1553-7390, 08/2009, Volume 5, Issue 8, p. e1000622
  The checkpoint kinases ATM and ATR are redundantly required for maintenance of stable telomeres in diverse organisms, including budding and fission yeasts,... 
Proteins | Enzymes | Yeast | Deoxyribonucleic acid | DNA | Organisms | Experiments | Telomerase | Binding sites
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2013, Volume 8, Issue 11, p. e79649
Journal Article
by Thorsson, Vesteinn and Thorsson, Vésteinn and Gibbs, Richard A and Gibbs, David L and Brown, Scott D and Wolf, Gregory and Wolf, Denise and Bortone, Dante S and Ou Yang, Tai-Hsien and Porta-Pardo, Eduard and Gao, Galen F and Gao, Jianjiong and Plaisier, Christopher L and Eddy, James A and Ziv, Elad and Culhane, Aedin C and Paull, Evan O and Sivakumar, I.K. Ashok and Gentles, Andrew J and Malhotra, Raunaq and Farshidfar, Farshad and Colaprico, Antonio and Parker, Joel S and Mose, Lisle E and Vo, Nam Sy and Liu, Wenbin and Liu, Jianfang and Liu, Jia and Liu, Yuexin and Liu, Xiuping and Rader, Janet and Dhankani, Varsha and Reynolds, Sheila and Reynolds, Sheila M and Bowlby, Reanne and Califano, Andrea and Cherniack, Andrew D and Anastassiou, Dimitris and Bedognetti, Davide and Mokrab, Younes and Newman, Aaron M and Rao, Arvind and Chen, Amy and Chen, Chu and Chen, Ken and Krasnitz, Alexander and Hu, Jianhong and Hu, Hai and Malta, Tathiane M and Noushmehr, Houtan and Pedamallu, Chandra Sekhar and Bullman, Susan and Ojesina, Akinyemi I and Lamb, Andrew and Zhou, Wanding and Shen, Hui and Choueiri, Toni K and Weinstein, John N and Guinney, Justin and Saltz, Joel and Holt, Robert and Holt, Robert A and Rabkin, Charles S and Caesar-Johnson, Samantha J and Demchok, John A and Felau, Ina and Kasapi, Melpomeni and Ferguson, Martin L and Hutter, Carolyn M and Sofia, Heidi J and Tarnuzzer, Roy and Wang, Jioajiao and Wang, Min and Wang, Linghua and Wang, Zhining and Wang, Timothy and Wang, Jing and Yang, Ju Dong and Yang, Hannah and Yang, Liming and Yang, Ian and Zenklusen, Jean C and Zhang, Jiashan (Julia) and Zhang, Jiexin and Zhang, Lizhi and Zhang, Wei and Zhang, Hongzheng and Zhang, Hailei and Zhang, Hongxin and Chudamani, Sudha and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Sun, Yichao and Sun, Qiang and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and ... and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network
Immunity, ISSN 1074-7613, 04/2018, Volume 48, Issue 4, pp. 812 - 830.e14
We performed an extensive immunogenomic analysis of more than 10,000 tumors comprising 33 diverse cancer types by utilizing data compiled by TCGA. Across... 
tumor immunology | immunotherapy | cancer genomics | integrative network analysis | immuno-oncology | tumor microenvironment | immune subtypes | immunomodulatory | Immunology | Infectious Diseases | Immunology and Allergy | GENOMIC ANALYSES | INFORMATION | T-CELL-RECEPTOR | REGULATORY NETWORK | CLASSIFICATION | IMMUNOLOGY | SEQUENCING DATA | SOMATIC MUTATIONS | COMPREHENSIVE ANALYSIS | PREDICTION | REVEALS | Transforming Growth Factor beta - immunology | Prognosis | Humans | Middle Aged | Th1-Th2 Balance - physiology | Male | Neoplasms - classification | Wound Healing - immunology | Young Adult | Transforming Growth Factor beta - genetics | Neoplasms - genetics | Neoplasms - immunology | Interferon-gamma - immunology | Adolescent | Aged, 80 and over | Adult | Female | Aged | Interferon-gamma - genetics | Wound Healing - genetics | Genomics - methods | Child | Macrophages - immunology | Cell proliferation | Cluster analysis | Transcription | Copy number | p53 Protein | Lung cancer | Genomics | Aneuploidy | Lymphocytes T | Genomes | Cell interactions | Macrophages | Immunotherapy | DNA methylation | Deoxyribonucleic acid--DNA | Immune system | Medical research | Wound healing | Immunomodulation | MiRNA | Stockholders | Inflammation | T cell receptors | Communications networks | Gene expression | White blood cells | Inventors | Medical prognosis | γ-Interferon | Mutation | Cancer | Tumors | Immune Subtypes | Integrative Network Analysis | Cancer Genomics | Immuno-oncology | Tumor immunology
Journal Article