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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 09/2015, Volume 112, Issue 37, p. 11672
  In regions with high malaria endemicity, the withdrawal of chloroquine (CQ) as first-line treatment of Plasmodium falciparum infections has typically led to... 
Malaria | Genomes | Parasites | Mutation | Drug resistance | Adaptation
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2013, Volume 110, Issue 50, p. 20129
  Analysis of genome sequences of 159 isolates of Plasmodium falciparum from Senegal yields an extraordinarily high proportion (26.85%) of protein-coding genes... 
Malaria | Evolutionary biology | Parasitic protozoa | Population genetics | Life cycles | Polymorphism
Journal Article
Nature, ISSN 0028-0836, 2016, Volume 538, Issue 7625, pp. 344 - 349
Antimalarial drugs have thus far been chiefly derived from two sources-natural products and synthetic drug-like compounds. Here we investigate whether... 
IN-VITRO | TRANSFER-RNA SYNTHETASE | MALARIA CONTROL | PLASMODIUM-FALCIPARUM | MULTIDISCIPLINARY SCIENCES | DRUG DISCOVERY | LIVER | TARGETS | PROTEIN-SYNTHESIS | NEXT-GENERATION | HEPATIC STAGES | Azabicyclo Compounds - pharmacology | Plasmodium falciparum - enzymology | Malaria, Falciparum - prevention & control | Male | Plasmodium falciparum - cytology | Azetidines - pharmacology | Plasmodium falciparum - drug effects | Cytosol - enzymology | Malaria, Falciparum - transmission | Liver - drug effects | Azabicyclo Compounds - chemical synthesis | Azabicyclo Compounds - therapeutic use | Female | Safety | Antimalarials - chemical synthesis | Disease Models, Animal | Life Cycle Stages - drug effects | Malaria, Falciparum - drug therapy | Azabicyclo Compounds - administration & dosage | Azetidines - adverse effects | Phenylurea Compounds - therapeutic use | Antimalarials - therapeutic use | Macaca mulatta - parasitology | Phenylalanine-tRNA Ligase - antagonists & inhibitors | Drug Discovery | Antimalarials - pharmacology | Animals | Azetidines - administration & dosage | Phenylurea Compounds - chemical synthesis | Antimalarials - administration & dosage | Azetidines - therapeutic use | Phenylurea Compounds - administration & dosage | Mice | Phenylurea Compounds - pharmacology | Liver - parasitology | Plasmodium falciparum - growth & development | Prevention | Antimalarials | Disease transmission | Health aspects | Transfer RNA | Proteins | Cytochrome | Malaria | Liver | Parasites | Kinases | Drug resistance | Drug dosages
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 11/2015, Volume 373, Issue 21, pp. 2025 - 2037
Journal Article
Nature Biotechnology, ISSN 1087-0156, 12/2018, Volume 36, Issue 11, pp. 1067 - 1080
Although shotgun metagenomic sequencing of microbiome samples enables partial reconstruction of strain-level community structure, obtaining high-quality... 
MICROORGANISMS | STRAINS | SINGLE-CELL | BACTERIA | ACCURATE | METAGENOMICS | SEDIMENT | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | DIVERSITY | Science | Microbial genetics | Usage | Research | Analysis | Computer programs | Community structure | Sediment samplers | Microorganisms | Clouds | Microbiomes | Genomes | Assembly | Gene sequencing
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2015, Volume 112, Issue 37, pp. 11672 - 11677
Journal Article
Science Translational Medicine, ISSN 1946-6234, 05/2016, Volume 8, Issue 339, pp. 339ra71 - 339ra71
Journal Article
PloS one, 2017, Volume 12, Issue 8, p. e0182585
Immunocompromised individuals are at high risk of developing Clostridium difficile-associated disease (CDAD). Fecal microbiota transplantation (FMT) is a... 
Enterocolitis, Pseudomembranous - therapy | Humans | Middle Aged | Bacteria - classification | Hematopoietic Stem Cell Transplantation | Adult | Female | Male | Treatment Outcome | Aged | Immunocompromised Host | Fecal Microbiota Transplantation
Journal Article
Genome Biology, ISSN 1474-7596, 2014, Volume 15, Issue 11, pp. 511 - 511
Background: Drug resistance remains a major public health challenge for malaria treatment and eradication. Individual loci associated with drug resistance to... 
COMPENSATORY MUTATIONS | EVOLVABILITY | POPULATION | ACID | INHIBITION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | PLASMODIUM-FALCIPARUM | PERMEATION PATHWAYS | GENETICS & HEREDITY | VALIDATION | RED-BLOOD-CELLS | MOLECULAR-CLONING | Research
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