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Neuron, ISSN 0896-6273, 2009, Volume 63, Issue 1, pp. 27 - 39
Examining the behavioral consequences of selective CNS neuronal activation is a powerful tool for elucidating mammalian brain function in health and disease.... 
SYSNEURO | MOLNEURO | M-CHANNEL | INHIBITION | IN-VIVO | G(I)-COUPLED RECEPTOR | CONDITIONAL EXPRESSION | MAMMALIAN NEURONS | LIGAND | OSCILLATIONS | NEUROSCIENCES | Membrane Potentials - genetics | Locomotion - genetics | Receptors, G-Protein-Coupled - metabolism | Gene Expression - genetics | Humans | Stereotyped Behavior - drug effects | Patch-Clamp Techniques - methods | Brain - metabolism | Dose-Response Relationship, Drug | Clozapine - pharmacology | Time Factors | Neurons - physiology | Behavior, Animal - drug effects | GTP-Binding Protein alpha Subunits, Gq-G11 - metabolism | Neurons - drug effects | Locomotion - drug effects | Membrane Potentials - drug effects | Stereotyped Behavior - physiology | GTP-Binding Protein alpha Subunits, Gq-G11 - genetics | Brain - cytology | Mice, Transgenic | Clozapine - analogs & derivatives | Hippocampus - cytology | Evoked Potentials - drug effects | Animals | Evoked Potentials - genetics | Doxycycline - pharmacology | Mice | Receptors, G-Protein-Coupled - genetics | In Vitro Techniques | Evolution, Molecular | Neurosciences | Neurons | Pharmacy | Genetic engineering | Universities and colleges | Seizures (Medicine) | Medical screening | Membrane proteins | Proteins | Blood-brain barrier | Rodents | Ligands | Behavior | Gene expression | Binding sites | Methods | Index Medicus
Journal Article
Brain, Behavior, and Immunity, ISSN 0889-1591, 2019
The loss of central norepinephrine (NE) released by neurons of the locus coeruleus (LC) occurs with aging, and is thought to be an important factor in... 
Chronic neuroinflammation | Parkinson's diseases | Nonmotor symptoms | Norepinephrine | Progressive neurodegeneration | Locus coeruleus | Motor symptoms
Journal Article
Nature, ISSN 0028-0836, 11/2015, Volume 527, Issue 7579, pp. 477 - 483
At least 120 non-olfactory G-protein-coupled receptors in the human genome are 'orphans' for which endogenous ligands are unknown, and many have no selective... 
EXTRACELLULAR ACIDIFICATION | ACTIVATION | COMPLEX | OGR1 | PROTEIN-COUPLED RECEPTOR | MULTIDISCIPLINARY SCIENCES | CAMP ACCUMULATION | SMOOTH-MUSCLE-CELLS | EXPRESSION | CANCER | Anti-Anxiety Agents - metabolism | Lorazepam - pharmacology | Memory - drug effects | Receptors, G-Protein-Coupled - metabolism | Humans | Anti-Anxiety Agents - analysis | Male | Receptors, G-Protein-Coupled - agonists | Lorazepam - analysis | Benzyl Alcohols - pharmacology | HEK293 Cells | Anti-Anxiety Agents - chemistry | Female | Triazines - chemistry | Allosteric Regulation - drug effects | Benzyl Alcohols - chemistry | Triazines - metabolism | Triazines - pharmacology | Lorazepam - metabolism | Anti-Anxiety Agents - pharmacology | Models, Molecular | Drug Discovery | Mice, Knockout | Triazines - analysis | Fear | Animals | Receptors, G-Protein-Coupled - deficiency | Signal Transduction - drug effects | Benzyl Alcohols - analysis | Allosteric Site | Lorazepam - chemistry | Receptors, G-Protein-Coupled - antagonists & inhibitors | Conditioning, Classical | Benzyl Alcohols - metabolism | Ligands | Mice | Receptors, G-Protein-Coupled - chemistry | Physiological aspects | Cell receptors | Identification and classification | Ligands (Biochemistry) | Lorazepam | Analysis | Proteins | Yeast | Rodents | Physiology | Genomes | Kinases | Index Medicus | proton-sensing | virtual screening | GPR68 | GPR65 | positive allosteric modulator (PAM) | functional selectivity | allosteric modulator
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 04/2013, Volume 38, Issue 5, pp. 854 - 862
Journal Article
Neurobiology of Learning and Memory, ISSN 1074-7427, 09/2019, Volume 163, pp. 107044 - 107044
Activity of hippocampal pyramidal cells is critical for certain forms of learning and memory, and work from our lab and others has shown that CA2 neuronal... 
RGS14 | Amygdala | Hippocampal CA2 | hM3Dq | DREADD | hM4Di | Fear conditioning | AGGRESSIVE-BEHAVIOR | BASOLATERAL AMYGDALA | VENTRAL HIPPOCAMPUS | SYNAPTIC PLASTICITY | NEUROSCIENCES | PSYCHOLOGY | PSYCHOLOGY, MULTIDISCIPLINARY | LONG-TERM-POTENTIATION | MEDIAL PREFRONTAL CORTEX | BEHAVIORAL SCIENCES | PERINEURONAL NETS | SEX-DIFFERENCES | DIFFERENT ANTEROGRADE AMNESIAS | DORSAL | Index Medicus
Journal Article
Neuropharmacology, ISSN 0028-3908, 09/2013, Volume 72, pp. 187 - 196
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 03/2018, Volume 38, Issue 11, pp. 2671 - 2682
Journal Article