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Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2013, Volume 288, Issue 45, pp. 32539 - 32552
Journal Article
Acta crystallographica. Section F, Structural biology communications, ISSN 2053-230X, 04/2015, Volume 71, Issue Pt 5
P. falciparum orotate phosphoribosyltransferase, a potential target for antimalarial drugs and a conduit for prodrugs, crystallized as a structure with eight... 
CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND SUPERFLUIDITY | CHANNELING | POTENTIALS | DIMERS | INTERACTIONS | MOLECULES
Journal Article
Acta Crystallographica Section F Structural Biology Communications, ISSN 2053-230X, 05/2015, Volume 71, Issue 5, pp. 600 - 608
The most severe form of malaria is caused by the obligate parasitePlasmodium falciparum. Orotate phosphoribosyltransferase (OPRTase) is the fifth enzyme in... 
Journal Article
Journal Article
Journal Article
Molecular & Biochemical Parasitology, ISSN 0166-6851, 11/2016, Volume 210, Issue 1-2, pp. 1 - 4
Journal Article
Malaria Journal, ISSN 1475-2875, 11/2016, Volume 15, Issue 1, p. 569
Journal Article
Molecular & Biochemical Parasitology, ISSN 0166-6851, 11/2009, Volume 168, Issue 1, pp. 74 - 83
The plant-like, bifunctional dihydrofolate reductase-thymidylate synthase (DHFR-TS) from malaria parasites has been a good target for drug development.... 
Inhibitor | Kinetics | Malaria | Enzyme | RNA binding | GENES ENCODING ENZYMES | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | BIOCHEMICAL-CHARACTERIZATION | BACILLUS-STEAROTHERMOPHILUS | FOLATE ANTAGONISTS | THYMIDYLATE SYNTHASE INHIBITORS | PYRIDOXAL 5'-PHOSPHATE | DIHYDROFOLATE-REDUCTASE | MALARIA PARASITE | PARASITOLOGY | Coenzymes - pharmacology | Plasmodium falciparum - enzymology | Glycine Hydroxymethyltransferase - genetics | Recombinant Fusion Proteins - isolation & purification | Gene Expression | Pyridoxal Phosphate - pharmacology | Enzyme Inhibitors - pharmacology | Substrate Specificity | Glycine Hydroxymethyltransferase - metabolism | RNA, Messenger - metabolism | Glycine Hydroxymethyltransferase - isolation & purification | Recombinant Fusion Proteins - metabolism | Serine - metabolism | Tetrahydrofolates - metabolism | Recombinant Fusion Proteins - antagonists & inhibitors | Animals | Chromatography, Affinity | Escherichia coli - genetics | Cloning, Molecular | Protein Binding | Recombinant Fusion Proteins - genetics | Folic Acid Antagonists - pharmacology | Glycine Hydroxymethyltransferase - antagonists & inhibitors | Phosphates | Plasmodium falciparum | Messenger RNA | Physiological aspects | Amino acids | Dihydrofolate reductase | Ethers | Muscle proteins | Folic acid | enzyme | inhibitor | kinetics | RNA-binding
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2010, Volume 285, Issue 21, pp. 15916 - 15922
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 03/2010, Volume 396, Issue 5, pp. 1244 - 1259
Purine nucleoside phosphorylases (PNPs) and uridine phosphorylases (UPs) are closely related enzymes involved in purine and pyrimidine salvage, respectively,... 
pyrimidine salvage | nucleoside phosphorylase | gene annotation | nucleotide metabolism | sleeping sickness | Sleeping sickness | Nucleoside phosphorylase | Pyrimidine salvage | Gene annotation | Nucleotide metabolism | PYRIMIDINE METABOLISM | PURINE | PROTEIN-STRUCTURE | LIGAND COMPLEXES | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | BRUCEI | PLASMODIUM-FALCIPARUM | PURIFICATION | GIARDIA-LAMBLIA | EXPRESSION | Protozoan Proteins - antagonists & inhibitors | Protein Multimerization | Molecular Sequence Data | Substrate Specificity | Crystallography, X-Ray | Genes, Protozoan | DNA Primers - genetics | Protozoan Proteins - genetics | Trypanosoma brucei brucei - enzymology | Protozoan Proteins - metabolism | RNA Interference | Base Sequence | Protein Structure, Quaternary | Protozoan Proteins - chemistry | Binding Sites | Uridine Phosphorylase - genetics | Recombinant Proteins - metabolism | Amino Acid Sequence | Catalytic Domain | Models, Molecular | Recombinant Proteins - chemistry | Uridine Phosphorylase - antagonists & inhibitors | Recombinant Proteins - genetics | Trypanosoma brucei brucei - genetics | Sequence Homology, Amino Acid | Metals - metabolism | Uridine Phosphorylase - metabolism | DNA, Protozoan - genetics | Uridine Phosphorylase - chemistry | Enzymes | RNA | Crystals | Polyols | Phosphorylase | Alkaloids | Pyrimidines | Particle accelerators | Polyethylene glycol | Physiological aspects | Nucleosides | Hydrolases | Structure
Journal Article
Antimicrobial agents and chemotherapy, ISSN 0066-4804, 07/2019, Volume 63, Issue 10
Artemisinin Combination Therapy (ACT) has been used to treat uncomplicated infections in India since 2004. Since 2008 decreasing artemisinin effectiveness has... 
RSA | kelch | PARASITE CLEARANCE | MICROBIOLOGY | Indian Plasmodium falciparum | EMERGENCE | GENOME | CAMBODIA | UGANDA | POLYMORPHISMS | artemisinin sensitivity | RESISTANCE | MALARIA | PHARMACOLOGY & PHARMACY | MUTATIONS | ASSOCIATION
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2003, Volume 278, Issue 27, p. 24324
Thermal inactivation of glucose oxidase (GOD; β- d -glucose: oxygen oxidoreductase), from Aspergillus niger , followed first order kinetics both in the... 
Journal Article
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