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Journal Article
by Collisson, Eric A and Campbell, Joshua D and Brooks, Angela N and Berger, Alice H and Lee, William and Chmielecki, Juliann and Beer, David G and Cope, Leslie and Creighton, Chad J and Danilova, Ludmila and Ding, Li and Getz, Gad and Hammerman, Peter S and Hayes, D. Neil and Hernandez, Bryan and Herman, James G and Heymach, John V and Jurisica, Igor and Kucherlapati, Raju and Kwiatkowski, David and Ladanyi, Marc and Robertson, Gordon and Schultz, Nikolaus and Shen, Ronglai and Sinha, Rileen and Sougnez, Carrie and Tsao, Ming-Sound and Travis, William D and Weinstein, John N and Wigle, Dennis A and Wilkerson, Matthew D and Chu, Andy and Cherniack, Andrew D and Hadjipanayis, Angela and Rosenberg, Mara and Weisenberger, Daniel J and Laird, Peter W and Radenbaugh, Amie and Ma, Singer and Stuart, Joshua M and Byers, Lauren Averett and Baylin, Stephen B and Govindan, Ramaswamy and Meyerson, Matthew and Gabriel, Stacey B and Cibulskis, Kristian and Kim, Jaegil and Stewart, Chip and Lichtenstein, Lee and Lander, Eric S and Lawrence, Michael S and Getz, E and Fulton, Robert and Fulton, Lucinda L and McLellan, Michael D and Wilson, Richard K and Ye, Kai and Fronick, Catrina C and Maher, Christopher A and Miller, Christopher A and Wendl, Michael C and Cabanski, Christopher and Mardis, Elaine and Wheeler, David and Balasundaram, Miruna and Butterfield, Yaron S. N and Carlsen, Rebecca and Chuah, Eric and Dhalla, Noreen and Guin, Ranabir and Hirst, Carrie and Lee, Darlene and Li, Haiyan I and Mayo, Michael and Moore, Richard A and Mungall, Andrew J and Schein, Jacqueline E and Sipahimalani, Payal and Tam, Angela and Varhol, Richard and Robertson, A. Gordon and Wye, Natasja and Thiessen, Nina and Holt, Robert A and Jones, Steven J.M and Marra, Marco A and Imielinski, Marcin and Onofrio, Robert C and Hodis, Eran and Zack, Travis and Helman, Elena and Pedamallu, Chandra Sekhar and Mesirov, Jill and Saksena, Gordon and Schumacher, Steven E and Carter, Scott L and Garraway, Levi and Beroukhim, Rameen and Lee, Semin and Mahadeshwar, Harshad S and ...
Nature, ISSN 0028-0836, 2014, Volume 511, Issue 7511, pp. 543 - 550
Journal Article
by McKay, J.D and Hung, R.J and Han, Y and Zong, X and Carreras-Torres, R and Christiani, D.C and Caporaso, N and Johansson, M and Li, Y and Byun, J.Y and Dunning, A and Pooley, K.A and Qian, D.C and Liu, G and Bojesen, S.E and Wu, X and Marchand, L. le and Albanes, D and Bickeböller, H and Alich, M.C and Bush, W.S and Tardon, A and Rennert, G and Teare, M.D and Field, J.K and Kiemeney, L.A and Lazarus, P and Haugen, A and Schabath, M.B and Anew, A.S and Shen, H and Hong, Y.C and Yuan, J.M and Bertazzi, P.A and Pesatori, A.C and Ye, Y and Diao, N and Su, L and Zhang, R and Brhane, Y and Leighl, N and Johansen, J.S and Mellemgaard, A and Saliba, W and Haiman, C.A and Wilkens, L.R and Fernandez-Somoano, A and Fernandez-Tardon, G and Heijden, H.F.M. van der and Kim, J.H and Hu, Z and Davies, M and Brunnström, H and Manjer, J and Melander, O and Muller, D and Overvad, K and Trichopoulou, A and Tumino, R and Doherty, J.A and Barnett, M.P and Chen, C and Goodman, G.E and Cox, A and Taylor, F and Woll, P.J and Brüske, I and Wichmann, H.E and Manz, J and Muley, T.R and Risch, A and Rosenberger, A and Grankvist, K and Shepherd, F.A and Tsao, M.S and Haura, E.B and Bolca, C and Holcatova, I and Janout, V and Kontic, M and Lissowska, J and Mukeria, A and Ognjanovic, S and Orlowski, T.M and Scelo, G and Swiatkowska, B and Zaridze, D and Bakke, P and Skaug, V and Zienolddiny, S and Duell, E.J and Butler, L.M and Koh, W.P and Gao, Y.T and Houlston, R.S and McLaughlin, J and Stevens, V.L and Joubert, P and Lamontagne, M and Nickle, D.C and ... and SpiroMeta Consortium and Medicinska fakulteten and Institutionen för medicinsk biovetenskap and Institutionen för strålningsvetenskaper and Umeå universitet
Nature Genetics, ISSN 1061-4036, 2017, Volume 49, Issue 7, pp. 1126 - 1132
Journal Article
by George, Julie and Lim, Jing Shan and Jang, Se Jin and Cun, Yupeng and Ozretia, Luka and Kong, Gu and Leenders, Frauke and Lu, Xin and Fernández-Cuesta, Lynnette and Bosco, Graziella and Müller, Christian and Dahmen, Ilona and Jahchan, Nadine S and Park, Kwon-Sik and Yang, Dian and Karnezis, Anthony N and Vaka, Dedeepya and Torres, Angela and Wang, Maia Segura and Korbel, Jan O and Menon, Roopika and Chun, Sung-Min and Kim, Deokhoon and Wilkerson, Matt and Hayes, Neil and Engelmann, David and Pützer, Brigitte and Bos, Marc and Michels, Sebastian and Vlasic, Ignacija and Seidel, Danila and Pinther, Berit and Schaub, Philipp and Becker, Christian and Altmüller, Janine and Yokota, Jun and Kohno, Takashi and Iwakawa, Reika and Tsuta, Koji and Noguchi, Masayuki and Muley, Thomas and Hoffmann, Hans and Schnabel, Philipp A and Petersen, Iver and Chen, Yuan and Soltermann, Alex and Tischler, Verena and Choi, Chang-Min and Kim, Yong-Hee and Massion, Pierre P and Zou, Yong and Jovanovic, Dragana and Kontic, Milica and Wright, Gavin M and Russell, Prudence A and Solomon, Benjamin and Koch, Ina and Lindner, Michael and Muscarella, Lucia A and La Torre, Annamaria and Field, John K and Jakopovic, Marko and Knezevic, Jelena and Castaños-Vélez, Esmeralda and Roz, Luca and Pastorino, Ugo and Brustugun, Odd-Terje and Lund-Iversen, Marius and Thunnissen, Erik and Köhler, Jens and Schuler, Martin and Botling, Johan and Sandelin, Martin and Sanchez-Cespedes, Montserrat and Salvesen, Helga B and Achter, Viktor and Lang, Ulrich and Bogus, Magdalena and Schneider, Peter M and Zander, Thomas and Ansén, Sascha and Hallek, Michael and Wolf, Jürgen and Vingron, Martin and Yatabe, Yasushi and Travis, William D and Nürnberg, Peter and Reinhardt, Christian and Perner, Sven and Heukamp, Lukas and Büttner, Reinhard and Haas, Stefan A and Brambilla, Elisabeth and Peifer, Martin and Sage, Julien and Thomas, Roman K and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för immunologi, genetik och patologi and Lungmedicin och allergologi and Uppsala universitet and Institutionen för medicinska vetenskaper
Nature, ISSN 0028-0836, 08/2015, Volume 524, Issue 7563, pp. 47 - 53
We have sequenced the genomes of 110 small cell lung cancers (SCLC), one of the deadliest human cancers. In nearly all the tumours analysed we found bi-allelic... 
NEUROENDOCRINE TUMORS | PATHWAY | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | IN-VIVO | GENES | CYCLE ARREST | NOTCH | C-KIT | MUTATIONS | CARCINOMA | Neurosecretory Systems - pathology | Receptors, Notch - metabolism | Chromosome Breakpoints | Genomics | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | Male | Receptors, Notch - genetics | Gene Expression Profiling | Tumor Suppressor Protein p53 - genetics | Small Cell Lung Carcinoma - metabolism | Tumor Suppressor Proteins - genetics | Neurosecretory Systems - metabolism | Female | Nuclear Proteins - genetics | Disease Models, Animal | Lung Neoplasms - genetics | Signal Transduction - genetics | Small Cell Lung Carcinoma - genetics | DNA-Binding Proteins - genetics | Mutation - genetics | Genome, Human - genetics | Small Cell Lung Carcinoma - pathology | Tumor Protein p73 | Animals | Cyclin D1 - genetics | Retinoblastoma Protein - genetics | Alleles | Cell Line, Tumor | Mice | Gene mutations | Analysis | Exome sequencing | Lung cancer, Small cell | Genetic aspects | Drug therapy | Cancer | Pathogenesis | Lung cancer | Genomes | Mutation | Kinases | Gene expression | Cancer therapies | Tumors | Index Medicus | Clinical Medicine | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Cancer and Oncology | Klinisk medicin | Cancer och onkologi
Journal Article
by Peifer, Martin and Fernández-Cuesta, Lynnette and Sos, Martin L and George, Julie and Seidel, Danila and Kasper, Lawryn H and Plenker, Dennis and Leenders, Frauke and Sun, Ruping and Zander, Thomas and Menon, Roopika and Koker, Mirjam and Dahmen, Ilona and Müller, Christian and Di Cerbo, Vincenzo and Schildhaus, Hans-Ulrich and Altmüller, Janine and Baessmann, Ingelore and Becker, Christian and De Wilde, Bram and Vandesompele, Jo and Böhm, Diana and Ansén, Sascha and Gabler, Franziska and Wilkening, Ines and Heynck, Stefanie and Heuckmann, Johannes M and Lu, Xin and Carter, Scott L and Cibulskis, Kristian and Banerji, Shantanu and Getz, Gad and Park, Kwon-Sik and Rauh, Daniel and Grütter, Christian and Fischer, Matthias and Pasqualucci, Laura and Wright, Gavin and Wainer, Zoe and Russell, Prudence and Petersen, Iver and Chen, Yuan and Stoelben, Erich and Ludwig, Corinna and Schnabel, Philipp and Hoffmann, Hans and Muley, Thomas and Brockmann, Michael and Engel-Riedel, Walburga and Muscarella, Lucia A and Fazio, Vito M and Groen, Harry and Timens, Wim and Sietsma, Hannie and Thunnissen, Erik and Smit, Egber and Heideman, Daniëlle A. M and Snijders, Peter J. F and Cappuzzo, Federico and Ligorio, Claudia and Damiani, Stefania and Field, John and Solberg, Steinar and Brustugun, Odd Terje and Lund-Iversen, Marius and Sänger, Jörg and Clement, Joachim H and Soltermann, Alex and Moch, Holger and Weder, Walter and Solomon, Benjamin and Soria, Jean-Charles and Validire, Pierre and Besse, Benjamin and Brambilla, Elisabeth and Brambilla, Christian and Lantuejoul, Sylvie and Lorimier, Philippe and Schneider, Peter M and Hallek, Michael and Pao, William and Meyerson, Matthew and Sage, Julien and Shendure, Jay and Schneider, Robert and Büttner, Reinhard and Wolf, Jürgen and Nürnberg, Peter and Perner, Sven and Heukamp, Lukas C and Brindle, Paul K and Haas, Stefan and Thomas, Roman K
Nature Genetics, ISSN 1061-4036, 10/2012, Volume 44, Issue 10, pp. 1104 - 1110
Journal Article
Journal of pathology, ISSN 0022-3417, 2013, Volume 230, Issue 3, pp. 270 - 276
Journal Article
International Archives of Occupational and Environmental Health, ISSN 0340-0131, 11/2018, Volume 91, Issue 8, pp. 937 - 950
Radon is a risk factor for lung cancer and uranium miners are more exposed than the general population. A genome-wide interaction analysis was carried out to... 
Environmental Health | GWAS | Occupational Medicine/Industrial Medicine | Environment | Gene–environment interaction | Rehabilitation | Radon progeny | Occupational exposure | DNA repair | MORTALITY | RESIDENTIAL RADON | ASSOCIATION ANALYSIS | Gene-environment interaction | SUSCEPTIBILITY | DNA-REPAIR GENES | SMOKING | ANCESTRY | RADIATION | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | MUTATIONS | EXPOSURE | Lung Neoplasms - genetics | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Occupational Exposure - adverse effects | Humans | Middle Aged | Risk Factors | Genotype | Male | Carcinogens, Environmental - toxicity | Nerve Tissue Proteins - genetics | Case-Control Studies | Linkage Disequilibrium | Mining | Neoplasms, Radiation-Induced - genetics | Occupational Diseases - genetics | Uranium | Genetic Markers - radiation effects | Female | Ubiquitination - radiation effects | Receptors, Nicotinic - genetics | DNA Damage - radiation effects | Radon - toxicity | Uranium industry | Lung cancer | Oncology, Experimental | Genomics | Genetic research | Genetic aspects | Research | Health aspects | Risk factors | Cancer | Genes | Linkage disequilibrium | Lung | DNA damage | Radiation | Genomes | Consortia | Ubiquitination | Miners | Occupational health | Repair | Deoxyribonucleic acid--DNA | Radiation effects | Radon | Dealkylation | MiRNA | Health risks | Exposure | Sampling methods | Radiation protection | Radiation damage | Index Medicus
Journal Article
by Hammerman, Peter S and Voet, Doug and Lawrence, Michael S and Voet, Doug and Jing, Rui and Cibulskis, Kristian and Sivachenko, Andrey and Stojanov, Petar and McKenna, Aaron and Lander, Eric S and Gabriel, Stacey and Getz, Gad and Imielinski, Marcin and Helman, Elena and Hernandez, Bryan and Pho, Nam H and Meyerson, Matthew and Chu, Andy and Hye-Chun, Jung E and Mungall, Andrew J and Pleasance, Erin and Robertson, A. Gordon and Sipahimalani, Payal and Stoll, Dominik and Balasundaram, Miruna and Birol, Inanc and Butterfield, Yaron S.N and Chuah, Eric and Coope, Robin J.N and Corbett, Richard and Dhalla, Noreen and Guin, Ranabir and He, An and Hirst, Carrie and Hirst, Martin and Holt, Robert A and Lee, Darlene and Li, Haiyan I and Mayo, Michael and Moore, Richard A and Mungall, Karen and Nip, Ka Ming and Olshen, Adam and Schein, Jacqueline E and Slobodan, Jared R and Tam, Angela and Thiessen, Nina and Varhol, Richard and Zeng, Thomas and Zhao, Yongjun and Jones, Steven J.M and Marra, Marco A and Saksena, Gordon and Cherniack, Andrew D and Schumacher, Stephen E and Tabak, Barbara and Carter, Scott L and Nguyen, Huy and Onofrio, Robert C and Crenshaw, Andrew and Ardlie, Kristin and Beroukhim, Rameen and Winckler, Wendy and Protopopov, Alexei and Zhang, Jianhua and Hadjipanayis, Angela and Lee, Semin and Xi, Ruibin and Yang, Lixing and Ren, Xiaojia and Zhang, Hailei and Shukla, Sachet and Chen, Peng-Chieh and Haseley, Psalm and Lee, Eunjung and Chin, Lynda and Park, Peter J and Kucherlapati, Raju and Socci, Nicholas D and Liang, Yupu and Schultz, Nikolaus and Borsu, Laetitia and Lash, Alex E and Viale, Agnes and Sander, Chris and Ladanyi, Marc and Auman, J. Todd and Hoadley, Katherine A and Wilkerson, Matthew D and Shi, Yan and Liquori, Christina and Meng, Shaowu and Li, Ling and Turman, Yidi J and Topal, Michael D and Tan, Donghui and Waring, Scot and Buda, Elizabeth and Walsh, Jesse and Jones, Corbin D and ... and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network and The Cancer Genome Atlas Research Network
Nature, ISSN 0028-0836, 09/2012, Volume 489, Issue 7417, pp. 519 - 525
Journal Article