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PloS one, ISSN 1932-6203, 2012, Volume 7, Issue 7, p. e40976
Journal Article
Nature (London), ISSN 1476-4687, 2010, Volume 468, Issue 7326, pp. 968 - 972
Oncogenic mutations in the serine/threonine kinase B-RAF (also known as BRAF) are found in 50-70% of malignant melanomas(1). Pre-clinical studies have... 
TRANSFORMATION | CELLS | ACTIVATION | TUMOR PROGRESSION | GENE | SIGNALING PATHWAY | MULTIDISCIPLINARY SCIENCES | SENSITIVITY | BRAF | MUTATIONS | CANCER | Allosteric Regulation | Humans | Gene Expression Regulation, Neoplastic | Melanoma - enzymology | Gene Expression Profiling | MAP Kinase Signaling System | Mitogen-Activated Protein Kinase Kinases - metabolism | Melanoma - genetics | Indoles - pharmacology | Proto-Oncogene Proteins B-raf - metabolism | Proto-Oncogene Proteins B-raf - chemistry | Melanoma - metabolism | Proto-Oncogene Proteins - metabolism | Gene Library | Proto-Oncogene Proteins c-raf - genetics | MAP Kinase Kinase Kinases - genetics | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | Proto-Oncogene Proteins - genetics | Clinical Trials as Topic | MAP Kinase Kinase Kinases - metabolism | Enzyme Activation - drug effects | Open Reading Frames - genetics | Sulfonamides - pharmacology | Proto-Oncogene Proteins c-raf - metabolism | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Drug Resistance, Neoplasm - genetics | Sulfonamides - therapeutic use | Protein Kinase Inhibitors - therapeutic use | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Cell Line, Tumor | Indoles - therapeutic use | Protein Kinase Inhibitors - pharmacology | Drug Resistance, Neoplasm - drug effects | Mitogen-Activated Protein Kinases - metabolism | Protein research | Research | Properties | Protein kinases | Cancer cells | Cell lines | Biochemistry | Mutation | Kinases | Genes | Cancer
Journal Article
Nature (London), ISSN 1476-4687, 2009, Volume 461, Issue 7264, pp. 614 - 620
Journal Article
Nature communications, ISSN 2041-1723, 2018, Volume 9, Issue 1, pp. 3542 - 1
... A. Barrera1,6, Nicholas C. Huston1,7, Ari E. Friedland1, Xuebing Wu2, Jonathan S. Gootenberg 3, Omar O. Abudayyeh4, Vic E. Myer1, Christopher J. Wilson 1 and Patrick D... 
Medicine | Micro to mainframe links | Hypertext | Colleges & universities | HyperText Markup Language | Genetics | Biochemistry | Biophysics
Journal Article
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2014, Volume 111, Issue 8, pp. 3128 - 3133
Journal Article
BMC genomics, ISSN 1471-2164, 2018, Volume 19, Issue 1, pp. 212 - 10
Background: Understanding the diversity of repair outcomes after introducing a genomic cut is essential for realizing the therapeutic potential of genomic... 
CRISPR/CAS9 | NGS | Translocation detection | Next generation sequencing | Gene editing | UDiTaS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | DOUBLE-STRANDED BREAKS | MUTATIONS | CLEAVAGE
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2015, Volume 10, Issue 9, p. e0138486