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Nature Communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 1136 - 11
Journal Article
NATURE MEDICINE, ISSN 1078-8956, 09/2019, Volume 25, Issue 9, pp. 1415 - 1415
Journal Article
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 1575 - 1575
Journal Article
Cancer Discovery, ISSN 2159-8274, 09/2018, Volume 8, Issue 9, pp. 1096 - 1111
Clinically relevant subtypes exist for pancreatic ductal adenocarcinoma (PDAC), but molecular characterization is not yet standard in clinical care. We... 
HETEROGENEITY | MEK | INHIBITION | ONCOLOGY | DUCTAL ADENOCARCINOMA | SUBTYPES | RESISTANCE | SOMATIC ERCC2 MUTATIONS | BRAF | SIGNATURE | FIBROBLASTS
Journal Article
Clinical cancer research : an official journal of the American Association for Cancer Research, ISSN 1078-0432, 01/2020, p. clincanres.3467.2019
ctDNA offers a promising, non-invasive approach to monitor therapeutic efficacy in real-time. We explored whether the quantitative percent change in ctDNA... 
Journal Article
CLINICAL CANCER RESEARCH, ISSN 1078-0432, 01/2020, Volume 26, Issue 2, pp. 439 - 449
Purpose: Although patients with advanced-stage non-small cell lung cancers (NSCLC) harboring MET exon 14 skipping mutations (METex14) often benefit from MET... 
IMPACT | ACTIVATION | MODELS | ONCOLOGY | TYROSINE KINASE | ADENOCARCINOMAS | ACQUIRED-RESISTANCE | CRIZOTINIB | ANTITUMOR-ACTIVITY | INSIGHT | CONFERS RESISTANCE
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 02/2019, Volume 37, Issue 4_suppl, pp. 562 - 562
562 Background: This study was designed to assess the capability of perioperative ctDNA analysis to predict surgical outcome and recurrence following... 
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 02/2018, Volume 36, Issue 4_suppl, pp. 272 - 272
272 Background: Curative resection is possible following neoadjuvant treatment for LAPC, yet there is no method to identify patients beforehand who will have a... 
Journal Article
OncoImmunology, ISSN 2162-4011, 05/2018, Volume 7, Issue 5, p. e1423172
Background: Approximately 50% of melanomas harbor BRAF mutations. Treatment with BRAF +/− MEK inhibition is associated with favorable changes in the tumor... 
Vemurafenib | BRAF | IL-2 | Combination therapy | Melanoma | SURVIVAL | DABRAFENIB | CRITERIA | RECOGNITION | IMMUNOLOGY | TUMORS | HIGH-DOSE IL-2 | CANCER-PATIENTS | MEK INHIBITION | ONCOLOGY | MUTATION | REGULATORY T-CELLS
Journal Article
Cancer Discovery, ISSN 2159-8274, 04/2018, Volume 8, Issue 4, pp. 417 - 427
Clonal heterogeneity associated with acquired resistance presents a critical therapeutic challenge. Whole-exome sequencing of paired tumor biopsies and... 
Journal Article
Cancer discovery, 04/2018, Volume 8, Issue 4, p. 417
Clonal heterogeneity associated with acquired resistance presents a critical therapeutic challenge. Whole-exome sequencing of paired tumor biopsies and... 
Journal Article
JCO Precision Oncology, ISSN 2473-4284, 11/2018, Issue 2, pp. 1 - 15
Purpose Third-generation epidermal growth factor receptor (EGFR) inhibitors like nazartinib are active against EGFR mutation–positive lung cancers with... 
Journal Article
JCO precision oncology, ISSN 2473-4284, 2018, Volume 2018
Third-generation epidermal growth factor receptor (EGFR) inhibitors like nazartinib are active against mutation-positive lung cancers with T790M-mediated... 
Journal Article
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