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1981, Volume 36, no. 3., 191-280.
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Biophysical Journal, ISSN 0006-3495, 02/2018, Volume 114, Issue 3, pp. 366a - 366a
Journal Article
Acta Crystallographica Section A Foundations and Advances, ISSN 2053-2733, 07/2018, Volume 74, Issue a1, pp. a340 - a340
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2008, Shohan., ISBN 4876624720, 426
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1974, Kokumin bunko, 808, 194
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Science (New York, N.Y.), ISSN 0036-8075, 11/2018, Volume 362, Issue 6415, pp. 644 - 645
Ribonuclease P (RNase P) recognizes precursor transfer RNA (pre-tRNA) and processes it to generate mature tRNAs that are used for assembling proteins. Unlike... 
Proteins | Ribonuclease P | RNA | Saccharomyces cerevisiae | RNA, Transfer | Ribonuclease A | Enzymes | Yeast | tRNA | Measuring instruments | Catalysis | Ribonucleic acid--RNA | Substrates | Transfer RNA
Journal Article
Nature, ISSN 0028-0836, 06/2017, Volume 546, Issue 7660, pp. 617 - 621
Intron removal requires assembly of the spliceosome on precursor mRNA (pre-mRNA) and extensive remodelling to form the spliceosome's catalytic centre. Here we... 
U4/U6.U5 TRI-SNRNP | COMPLEX | PROTEIN | MESSENGER-RNA | MULTIDISCIPLINARY SCIENCES | MOLECULAR ARCHITECTURE | U2 SNRNP | CRYO-EM STRUCTURE | REQUIRES ATP | RNA Helicases - metabolism | Ribonucleoprotein, U2 Small Nuclear - chemistry | Spliceosomes - chemistry | Saccharomyces cerevisiae - genetics | Ribonucleoprotein, U5 Small Nuclear - metabolism | RNA Splicing Factors - chemistry | RNA Helicases - chemistry | Ribonucleoprotein, U4-U6 Small Nuclear - metabolism | RNA Helicases - ultrastructure | RNA Splicing Factors - metabolism | Spliceosomes - metabolism | RNA Splicing | Ribonucleoprotein, U2 Small Nuclear - metabolism | Base Sequence | Protein Domains | RNA Precursors - metabolism | Ribonucleoproteins, Small Nuclear - chemistry | Protein Stability | Ribonucleoprotein, U5 Small Nuclear - chemistry | Saccharomyces cerevisiae Proteins - ultrastructure | Catalytic Domain | Biocatalysis | Introns - genetics | RNA Splice Sites - genetics | Models, Molecular | Nuclear Proteins - metabolism | RNA Precursors - genetics | Spliceosomes - ultrastructure | Nuclear Proteins - chemistry | Saccharomyces cerevisiae - chemistry | Cryoelectron Microscopy | RNA Precursors - ultrastructure | Models, Biological | Saccharomyces cerevisiae Proteins - metabolism | Protein Binding | Ribonucleoprotein, U4-U6 Small Nuclear - chemistry | RNA, Small Nuclear - chemistry | RNA, Small Nuclear - metabolism | Ribonucleoproteins, Small Nuclear - metabolism | Saccharomyces cerevisiae Proteins - chemistry | Yeast | Ribonucleoproteins (small nuclear) | Molecular structure | mRNA | Saccharomyces | Ribonucleoproteins (U2 small nuclear) | Electron microscopy | Ribonucleic acid--RNA | snRNA | Proteins | DNA helicase | Transmission electron microscopy | Ribonucleic acids | Catalysis | Atomic structure | Saccharomyces cerevisiae
Journal Article
Nature, ISSN 0028-0836, 02/2013, Volume 494, Issue 7435, pp. 638 - 643
Journal Article
Nature structural & molecular biology, ISSN 1545-9993, 10/2017, Volume 24, Issue 10, pp. 791 - 799
The spliceosome excises introns from pre-messenger RNAs using an RNA-based active site cradled by a dynamic protein scaffold. A recent revolution in... 
Journal Article
RNA, ISSN 1355-8382, 04/2015, Volume 21, Issue 4, pp. 699 - 700
When I started my own research group at the MRC Laboratory of Molecular biology in 1987 I was told to initiate a completely new project. I was fascinated by... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | Ribonucleoprotein, U1 Small Nuclear - metabolism | Ribonucleoprotein, U1 Small Nuclear - genetics | HeLa Cells | RNA - chemistry | Humans | RNA - genetics | Personal Reflections
Journal Article
Nature, ISSN 0028-0836, 07/2016, Volume 537, Issue 7619, pp. 197 - 201
Precursor mRNA (pre-mRNA) splicing proceeds by two consecutive transesterification reactions via a lariat-intron intermediate. Here we present the 3.8 angstrom... 
U4/U6.U5 TRI-SNRNP | IN-VITRO | ELECTRON CRYOMICROSCOPY | ACTIVE-SITE | CRYSTAL-STRUCTURE | CONFORMATIONAL REARRANGEMENT | MULTIDISCIPLINARY SCIENCES | SACCHAROMYCES-CEREVISIAE | U6 SNRNA | PRE-MESSENGER-RNA | CATALYTIC ACTIVATION | RNA Precursors - chemistry | RNA Helicases - metabolism | Spliceosomes - chemistry | RNA, Fungal - ultrastructure | Saccharomyces cerevisiae - genetics | Ribonucleoprotein, U5 Small Nuclear - metabolism | Saccharomyces cerevisiae - ultrastructure | Ribonucleoprotein, U4-U6 Small Nuclear - metabolism | RNA Splicing Factors - metabolism | Spliceosomes - metabolism | RNA Splicing | RNA, Small Nuclear - genetics | Base Sequence | RNA Precursors - metabolism | RNA, Fungal - genetics | Ribonucleoprotein, U5 Small Nuclear - chemistry | Saccharomyces cerevisiae Proteins - ultrastructure | Catalytic Domain | Introns - genetics | RNA Splice Sites - genetics | RNA, Fungal - chemistry | Adenosine Triphosphatases - metabolism | Models, Molecular | Exons - genetics | Magnesium - metabolism | Nuclear Proteins - metabolism | Spliceosomes - ultrastructure | Esterification | Saccharomyces cerevisiae - chemistry | RNA, Fungal - metabolism | Cryoelectron Microscopy | RNA Precursors - ultrastructure | Base Pairing | Saccharomyces cerevisiae Proteins - metabolism | Adenosine - metabolism | Ribonucleoprotein, U4-U6 Small Nuclear - chemistry | RNA, Small Nuclear - chemistry | RNA, Small Nuclear - metabolism | Saccharomyces cerevisiae Proteins - chemistry | Genetic aspects | Spliceosomes | Structure | Brewer's yeast | Methods | RNA splicing | Proteins | Enzymes | Molecular structure | Microscopy | Catalysis | Ribonucleic acid--RNA | Binding sites
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Environmental Toxicology and Chemistry, ISSN 0730-7268, 03/2015, Volume 34, Issue 3, p. 677
  Although species sensitivity distribution (SSD) is a key concept for quantitative ecological risk assessment, its application is limited owing to a lack of... 
Herbicides | Data analysis | Toxicity | Risk assessment | Algae | Environmental impact
Journal Article
Environmental Toxicology and Chemistry, ISSN 0730-7268, 03/2015, Volume 34, Issue 3, pp. 677 - 684
Journal Article
Nature, ISSN 0028-0836, 02/2016, Volume 530, Issue 7590, pp. 298 - 302
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Diabetes, ISSN 0012-1797, 11/2009, Volume 58, Issue 11, pp. 2574 - 2582
Journal Article
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