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Annals of Nutrition & Metabolism, ISSN 0250-6807, 10/2017, Volume 71, p. 140
Amino acids are known as building blocks of proteins and substrates of metabolic and biosynthetic reactions. However amino acids are also recognized as the... 
TOR protein | Cell proliferation | Biotechnology | Phosphorylation | Nutrient transport | Amino acids | Rapamycin | Leucine | Tumor cell lines | Metabolism | Nutrient uptake | Molecular chains | Substrates | Proteins | Signal transduction | Signaling | Pathways | Phosphoproteins | Proteomics | Cell lines | Nutrients | Transport | Transporter | Cancer
Journal Article
The Japanese Journal of SURGICAL METABOLISM and NUTRITION, ISSN 0389-5564, 2017, Volume 51, Issue 3, pp. 62 - 62
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2006, Volume 103, Issue 6, pp. 1723 - 1726
Journal Article
Journal Article
Cancer Science, ISSN 1347-9032, 11/2014, Volume 105, Issue 11, pp. 1496 - 1502
Journal Article
Cancer Science, ISSN 1347-9032, 10/2016, Volume 107, Issue 10, pp. 1499 - 1505
System l amino acid transporter 1 (LAT1) is highly expressed in various types of human cancer, and contributes to cancer growth and survival. Recently, we have... 
system l amino acid transporter 1 | mammalian target of rapamycin | esophageal cancer | molecular target | 2‐Aminobicyclo‐(2,2,1)‐heptane‐2‐carboxylic acid | 2-Aminobicyclo-(2,2,1)-heptane-2-carboxylic acid | APOPTOSIS | HIGH EXPRESSION | AUTOPHAGY | ESTABLISHMENT | 1)-heptane-2-carboxylic acid | LAT1 | HEAVY-CHAIN | ONCOLOGY | CLONING | 2-Aminobicyclo- | GROWTH | PROGNOSTIC-SIGNIFICANCE | PROGRESSION | Lactate Dehydrogenases - metabolism | Amino Acid Transport System L - metabolism | TOR Serine-Threonine Kinases - metabolism | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Humans | Amino Acid Transport System L - antagonists & inhibitors | Transcriptome | Male | Gene Expression Profiling | Antineoplastic Agents - administration & dosage | Molecular Targeted Therapy | Esophageal Neoplasms - pathology | Fusion Regulatory Protein-1 - genetics | Amino Acids - metabolism | Esophageal Neoplasms - metabolism | Antineoplastic Agents - pharmacology | Biological Transport - drug effects | Disease Models, Animal | Esophageal Squamous Cell Carcinoma | Amino Acid Transport System L - genetics | Xenograft Model Antitumor Assays | Animals | Carcinoma, Squamous Cell - drug therapy | Esophageal Neoplasms - genetics | Signal Transduction - drug effects | Cell Cycle Checkpoints - drug effects | Cell Line, Tumor | Fusion Regulatory Protein-1 - metabolism | Cell Proliferation - drug effects | Mice | Esophageal Neoplasms - drug therapy | Prevention | Glucose metabolism | Squamous cell carcinoma | Analysis | Amino acids | Health aspects | Esophageal cancer | Cancer | TOR protein | Cell proliferation | Phosphorylation | Therapeutic applications | Rapamycin | Carboxylic acids | Leucine | Tumor cell lines | Cancer therapies | Esophagus | Cell growth | Medical prognosis | Cell lines | Penicillin | Cell cycle | Drug dosages | Deoxyribonucleic acid--DNA | G1 phase | Original
Journal Article
Journal Article
Nature Structural and Molecular Biology, ISSN 1545-9993, 06/2019, Volume 26, Issue 6, pp. 510 - 517
The L-type amino acid transporter 1 (LAT1 or SLC7A5) transports large neutral amino acids across the membrane and is crucial for brain drug delivery and tumor... 
SYSTEM | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL PROLIFERATION | CELL BIOLOGY | LAT1 | HEAVY-CHAIN | BIOPHYSICS | MUTATIONS | MOLECULAR-BASIS | EXPRESSION | BINDING | INSIGHTS | Amino acids | Glycoproteins | Research | Drugs | Brain | Drug delivery systems | Brain tumors | Glycoprotein | Antibodies | Drug delivery | Epitopes | Cholesterol | Polysaccharides | Transporter | Assembly
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2016, Volume 113, Issue 3, pp. 775 - 780
Journal Article
Journal of Surgical Oncology, ISSN 0022-4790, 03/2016, Volume 113, Issue 4, pp. 381 - 389
Background Amino acid transporters are highly expressed in various human cancers. L‐type amino acid transporter 1 (LAT1) and system alanine‐serine‐cysteine... 
LAT1 | esophageal cancer |