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Frontiers in Physiology, ISSN 1664-042X, 2014, Volume 5, p. 98
Journal Article
Brain Behavior and Immunity, ISSN 0889-1591, 08/2019, Volume 80, pp. 146 - 162
Gintonin (GT), a ginseng-derived lysophosphatidic acid receptor ligand, regulates various cellular effects and represses inflammation. However, little is known... 
Gintonin | Huntington’s disease | Adeno-associated viral vector | Lysophosphatidic acid receptor | 3-Nitropropionic acid | Nuclear factor erythroid 2-related factor 2
Journal Article
Current Drug Targets, ISSN 1389-4501, 2012, Volume 13, Issue 13, pp. 1659 - 1664
Ginseng, the root of Panax ginseng C.A. Meyer, is one of the oldest herbal medicines and induces a variety of physiological and pharmacological effects.... 
LPA receptors | Gintonin | Ginseng | Novel LPA-ginseng protein complex | CA2+-ACTIVATED CL-CURRENT | PHOSPHOLIPASE-C | INVOLVEMENT | HIGH-AFFINITY | novel LPA-ginseng protein complex | LIPID MEDIATOR | INHIBITION | CELL-MIGRATION | PHARMACOLOGY & PHARMACY | XENOPUS OOCYTES | EXPRESSION | AUTOTAXIN | gintonin
Journal Article
Food and Chemical Toxicology, ISSN 0278-6915, 11/2018, Volume 121, p. 254
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1016/j.fct.2018.09.005 The... 
Oxidases | Analysis | Protein kinases
Journal Article
Frontiers in Pharmacology, ISSN 1663-9812, 05/2018, Volume 9, Issue MAY, p. 515
Gintonin is a ginseng-derived lysophosphatidic acid receptor (LPAR) ligand. Although previous and studies demonstrated the therapeutic role of gintonin against... 
Gintonin | Multi-target | Parkinson's disease | Lysophosphatidic acid receptor | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | Research | Glycolipids | Drug therapy | Risk factors
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 04/2013, Volume 705, Issue 1-3, pp. 119 - 125
Ginseng exhibits beneficial effects on GABA receptor-related anxiety and sleep disorders. However, little is known regarding the cellular and molecular bases... 
GABAA receptor | Panax ginseng | Ginsenoside Rg3 | Xenopus oocyte | GABA | Ginsenoside Rg | receptor | Oocytes - drug effects | Receptors, GABA-A - physiology | Ginsenosides - pharmacology | Animals | Oocytes - physiology | Xenopus laevis
Journal Article
Journal of Ginseng Research, ISSN 1226-8453, 2018
Background: Gintonin (GT), a novel ginseng-derived exogenous ligand of lysophosphatidic acid (LPA) receptors, has been shown to induce cell proliferation and... 
Gintonin | p62/SQSTM1 | Autophagy-related genes | LC3 puncta | Autophagic flux
Journal Article
Food and Chemical Toxicology, ISSN 0278-6915, 01/2019, Volume 123, p. 125
Serotonin syndrome is an adverse reaction due to increased serotonin (5-hydroxytryptophan: 5-HT) concentrations in the central nervous system (CNS). The full... 
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 07/2019, Volume 307, p. 136
Since reproductive toxicity is associated with oxidative stress, nuclear factor [kappa]B (NF[kappa]B), a redox-sensitive transcription factor, may be involved... 
Testosterone | Pituitary hormones | Genetic engineering | Peroxidase | Cocaine
Journal Article
Molecular Neurobiology, ISSN 0893-7648, 6/2014, Volume 49, Issue 3, pp. 1400 - 1421
Journal Article
Molecular Neurobiology, ISSN 0893-7648, 1/2019, Volume 56, Issue 1, pp. 39 - 55
Gintonin, a ginseng-derived glycolipoprotein isolated from ginseng, has been shown to be neuroprotective in several neurological disorders such as Alzheimer’s... 
Neurology | Gintonin | Neuroprotection | Neurosciences | Biomedicine | Nrf2/HO-1 pathway | Neurobiology | Neuroinflammation | MPTP | Parkinson’s disease | Cell Biology | Substantia Nigra - physiopathology | Tyrosine 3-Monooxygenase - metabolism | Heme Oxygenase-1 - metabolism | Substantia Nigra - pathology | Apoptosis - drug effects | Dopaminergic Neurons - pathology | Plant Extracts - pharmacology | Humans | Motor Activity - drug effects | Male | Gliosis - physiopathology | Glial Fibrillary Acidic Protein - metabolism | Gliosis - pathology | Neuroprotective Agents - pharmacology | Dopaminergic Neurons - metabolism | Inflammation Mediators - metabolism | Corpus Striatum - pathology | Disease Models, Animal | Biomarkers - metabolism | Parkinson Disease - complications | Parkinson Disease - pathology | Corpus Striatum - physiopathology | Mice, Inbred C57BL | Neurotoxins - toxicity | Parkinson Disease - physiopathology | Gliosis - complications | Rotenone | Up-Regulation - drug effects | Animals | Signal Transduction - drug effects | NF-E2-Related Factor 2 - metabolism | Cell Line, Tumor | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | Oxidative Stress - drug effects | alpha-Synuclein - metabolism | Animal models | Parkinson's disease | Mesencephalon | MPP | Synuclein | Accumulation | Neurotoxicity | Neurodegeneration | Neostriatum | Heme | Movement disorders | Dopamine receptors | Dopamine | Neurodegenerative diseases | Cytokines | Therapeutic applications | Heme oxygenase (decyclizing) | Inflammation | Nitric-oxide synthase | Neurological diseases | Oxygenase | Cell death | Nitric oxide | Mice | Ginseng | Apoptosis
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 02/2018, Volume 115, p. 318
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1016/j.freeradbiomed.2017.12.018... 
Analysis | Methamphetamine | Protein kinases
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 02/2018, Volume 115, pp. 318 - 337
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 01/2019, Volume 297, p. 95
We investigated whether protein kinase C[delta] (PKC[delta]) mediates cocaine-induced hepatotoxicity in mice. Cocaine treatment (60 mg/kg, i.p.) significantly... 
Cytochrome c | Antioxidants | Cysteine | RNA | Ligases | Cocaine | DNA-ligand interactions | Protein kinases
Journal Article
by Jo, MG and Ikram, M and Jo, MH and Yoo, L and Chung, KC and Nah, SY and Hwang, H and Rhim, H and Kim, MO
MOLECULAR NEUROBIOLOGY, ISSN 0893-7648, 01/2019, Volume 56, Issue 1, pp. 39 - 55
Gintonin, a ginseng-derived glycolipoprotein isolated from ginseng, has been shown to be neuroprotective in several neurological disorders such as Alzheimer's... 
Gintonin | Neuroprotection | OXIDATIVE STRESS | Parkinson's disease | INVOLVEMENT | Neuroinflammation | ALPHA-SYNUCLEIN | PATHOLOGY | NEUROSCIENCES | TAUROURSODEOXYCHOLIC ACID | CELL-DEATH | HO-1 pathway | Nrf2 | ACID RECEPTOR ACTIVATION | MOUSE MODEL | KOREAN RED GINSENG | MPTP | PARKINSONS-DISEASE
Journal Article
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