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by Biccard, Bruce M and Madiba, Thandinkosi E and Kluyts, Hyla-Louise and Munlemvo, Dolly M and Madzimbamuto, Farai and Madzimbamuto, Farai D and Basenero, Apollo and Gordon, Christina Salmina and Gordon, Christina S and Youssouf, Coulibaly and Rakotoarison, RR and Rakotoarison, Sylvia R and Gobin, Veekash and Samateh, Ahmadou L and Sani, Chaibou M and Omigbodun, Akinyinka O and Amanor-Boadu, Simbo D and Tumukunde, Janat and Tumukunde, Janat T and Esterhuizen, JL and Esterhuizen, Tonya M and Manach, Yannick Le and Forget, Patrice and Elkhogia, Abdulaziz M and Mehyaoui, Ryad M and Mehyaoui, RM and Zoumeno, Eugene and Ndayisaba, Gabriel and Ndasi, Henry and Ndonga, Andrew KN and Ndonga, Andrew K N and Ngumi, Zipporah W W and Ngumi, Zipporah WW and Patel, MB and Patel, Ushmaben and Patel, Ushmah P and Ashebir, Daniel Zemenfes and Antwi-Kusi, Akwasi and Antwi-Kusi, Akwasi A K and Mbwele, Bernard and Sama, Hamza Doles and Elfiky, Mahmoud and Fawzy, Maher A and Fawzy, Maher and Pearse, Rupert M and Abadagan, Hippolyte and Abbas, N and Abdelatif, A Ibrahim and Abdoulaye, Traoré and Abd-rouf, A and Abduljalil, A and Abdulrahman, A and Abdurazig, S and Abokris, A and Abozaid, W and Abugassa, SOA and Abuhdema, F and Abujanah, SA and Abusamra, R and Abushnaf, A and Abusnina, SA and Abuzalout, TS and Ackermann, HM and Adamu, YB and Addanfour, A and Adeleke, DM and Adigun, TA and Adisa, AO and Adjignon, Sèhivè Valéry and Adu-Aryee, NA and Afolabi, BB and Agaba, AFX and Agaba, PKA and Aghadi, K and Agilla, H and Ahmed, Al-J and Ahmed, El-Z and Ahmed, M and Ahmed, B and Ahossi, Rene and Aji, SA and Akanyun, S and Akhideno, I and Akhter, M and Akinyemi, OA and Akkari, M and Akodjenou, Joseph and AL Samateh, AL and al Shams, ES and Alagbe-Briggs, OT and Alakkari, EA and Alalem, RB and Alashhab, M and Alatise, OI and Alatresh, A and Alayeb Alayeb, MSI and Albakosh, BA and Albert, F and Alberts, ANJD and Aldarrat, AD and ... and African Surg Outcomes Study ASOS and African Surgical Outcomes Study (ASOS) investigators
The Lancet, ISSN 0140-6736, 04/2018, Volume 391, Issue 10130, pp. 1589 - 1598
There is a need to increase access to surgical treatments in African countries, but perioperative complications represent a major global health-care burden.... 
MORTALITY | SURGERY | STATEMENT | MEDICINE, GENERAL & INTERNAL | COST-EFFECTIVENESS | DISEASES | RESCUE | GLOBAL HEALTH | INCOME COUNTRIES | FAILURE | CARE | Medical personnel | Low income groups | Surgical outcomes | Medical research | Risk groups | Complications | Mortality | Critical care | Patients | Clinical outcomes | Studies | Hospitals | Risk assessment | Surgery | Population | Public health
Journal Article
by Kluyts, H.-L and Kluyts, Hyla-Louise and le Manach, Y and Munlemvo, Dolly M and Munlemvo, D.M and Madzimbamuto, Farai and Madzimbamuto, F and Basenero, Apollo and Basenero, A and Coulibaly, Y and Coulibaly, Youssouf and Rakotoarison, R.R and Rakotoarison, S and Rakotoarison, Sylvia R and Gobin, V and Gobin, Veekash and Samateh, Ahmadou L and Samateh, A.L and Chaibou, M.S and Omigbodun, A.O and Omigbodun, Akinyinka O and Amanor-Boadu, S.D and Amanor-Boadu, Simbo D and Tumukunde, J and Tumukunde, Janat and Madiba, Thandinkosi E and Madiba, T.E and Pearse, R.M and Pearse, Rupert M and Biccard, Bruce M and Biccard, B.M and Abadagan, Hippolyte and Abbas, N and Abdelatif, A. Ibrahim and Abdoulaye, Traoré and Abd-rouf, A and Abduljalil, A and Abdulrahman, A and Abdurazig, S and Abokris, A and Abozaid, W and Abugassa, S.O.A and Abuhdema, F and Abujanah, S.A and Abusamra, R and Abushnaf, A and Abusnina, S.A and Abuzalout, T.S and Ackermann, H.M and Adamu, Y.B and Addanfour, A and Adeleke, D.M and Adigun, T.A and Adisa, A.O and Adjignon, Sèhivè Valéry and Adu-Aryee, N.A and Afolabi, B.B and Agaba, P.K.A and Agaba, A.F.X and Aghadi, K and Agilla, H and Ahmed, M and Ahmed, B and Ahmed, El.-Z and Ahmed, Al.-J and Ahossi, Rene and Aji, S.A and Akanyun, S and Akhideno, I and Akhter, M and Akinyemi, O.A and Akkari, M and Akodjenou, Joseph and AL Samateh, A.L and al Shams, E.S and Alagbe-Briggs, O.T and Alakkari, E.A and Alalem, R.B and Alashhab, M and Alatise, O.I and Alatresh, A and Alayeb Alayeb, M.S.I and Albakosh, B.A and Albert, F and Alberts, A.N.J.D and Aldarrat, A.D and Alfari, A and Alfetore, A and Algbali, M and Algddar, A and Algedar, H.A and Alghafoud, I.A and Alghazali, A and Alhajj, M and Alhendery Alhendery, A and Alhoty, F.F.H and Ali, Y.A and Ali, A and Alioune, Beye Seïdina and Alkassem, M.A and ... and African Surgical Outcomes Study AS and African Surgical Outcomes Study (ASOS) investigators
British Journal of Anaesthesia, ISSN 0007-0912, 12/2018, Volume 121, Issue 6, pp. 1357 - 1363
The African Surgical Outcomes Study (ASOS) showed that surgical patients in Africa have a mortality twice the global average. Existing risk assessment tools... 
preoperative | mortality | risk assessment | risk stratification | surgery | DERIVATION | SCORE | SORT | ANESTHESIOLOGY | COHORT | OUTCOMES
Journal Article
Nature, ISSN 0028-0836, 06/2015, Volume 522, Issue 7555, pp. 216 - 220
Multiple sclerosis involves an aberrant autoimmune response and progressive failure of remyelination in the central nervous system. Prevention of neural... 
MYELIN BASIC-PROTEIN | TRANSCRIPTS | GLUCOCORTICOIDS | MULTIPLE-SCLEROSIS | LYSOLECITHIN | RNA-SEQ | MULTIDISCIPLINARY SCIENCES | SPINAL-CORD | CENTRAL-NERVOUS-SYSTEM | DIFFERENTIATION | OLIGODENDROCYTE PROGENITOR CELLS | Oligodendroglia - metabolism | Encephalomyelitis, Autoimmune, Experimental - metabolism | Humans | Cerebellum - drug effects | Myelin Sheath - drug effects | Male | Receptors, Glucocorticoid - metabolism | Demyelinating Diseases - metabolism | MAP Kinase Signaling System | Myelin Sheath - metabolism | Oligodendroglia - drug effects | Female | Oligodendroglia - cytology | Demyelinating Diseases - pathology | Demyelinating Diseases - drug therapy | Disease Models, Animal | Multiple Sclerosis - metabolism | Germ Layers - drug effects | Germ Layers - pathology | Encephalomyelitis, Autoimmune, Experimental - pathology | Lysophosphatidylcholines | Pluripotent Stem Cells - cytology | Germ Layers - metabolism | Tissue Culture Techniques | Cerebellum - metabolism | Encephalomyelitis, Autoimmune, Experimental - drug therapy | Cerebellum - pathology | Pluripotent Stem Cells - metabolism | Phenotype | Regeneration - drug effects | Animals | Cell Differentiation - drug effects | Miconazole - pharmacology | Pluripotent Stem Cells - drug effects | Multiple Sclerosis - pathology | Mice | Clobetasol - pharmacology | Mitogen-Activated Protein Kinases - metabolism | Multiple Sclerosis - drug therapy | Medical research | Myelination | Multiple sclerosis | Stem cells | Physiological aspects | Medicine, Experimental | Research | Drugs | Proteins | Blood-brain barrier | Laboratories | Rodents | Clinical trials | FDA approval | Gene expression
Journal Article
by Bishop, David G and Bishop, David and Dyer, Robert A and Maswime, Salome and Rodseth, Reitze N and van Dyk, Dominique and Kluyts, Hyla-Louise and Tumukunde, Janat and Tumukunde, Janat T and Madzimbamuto, Farai D and Madzimbamuto, Farai and Elkhogia, Abdulaziz M and Ndonga, Andrew KN and Ndonga, Andrew K N and Ngumi, Zipporah W W and Ngumi, Zipporah WW and Omigbodun, Akinyinka O and Amanor-Boadu, Simbo D and Zoumenou, Eugene and Basenero, Apollo and Munlemvo, Dolly M and Youssouf, Coulibaly and Ndayisaba, Gabriel and Antwi-Kusi, Akwasi and Gobin, Veekash and Forget, Patrice and Mbwele, Bernard and Ndasi, Henry and Rakotoarison, RR and Rakotoarison, Sylvia R and Samateh, Ahmadou L and Mehyaoui, RM and Mehyaoui, Ryad and Patel-Mujajati, Ushmaben and Sani, Chaibou M and Esterhuizen, Tonya M and Esterhuizen, JL and Madiba, Thandinkosi E and Pearse, Rupert M and Biccard, Bruce M and Abadagan, Hippolyte and Abbas, N and Abdelatif, A Ibrahim and Abdoulaye, Traoré and Abd-rouf, A and Abduljalil, A and Abdulrahman, A and Abdurazig, S and Abokris, A and Abozaid, W and Abugassa, SOA and Abuhdema, F and Abujanah, SA and Abusamra, R and Abushnaf, A and Abusnina, SA and Abuzalout, TS and Ackermann, HM and Adamu, YB and Addanfour, A and Adeleke, DM and Adigun, TA and Adisa, AO and Adjignon, Sèhivè Valéry and Adu-Aryee, NA and Afolabi, BB and Agaba, AFX and Agaba, PKA and Aghadi, K and Agilla, H and Ahmed, El-Z and Ahmed, M and Ahmed, B and Ahmed, Al-J and Ahossi, Rene and Aji, SA and Akanyun, S and Akhideno, I and Akhter, M and Akinyemi, OA and Akkari, M and Akodjenou, Joseph and AL Samateh, AL and al Shams, ES and Alagbe-Briggs, OT and Alakkari, EA and Alalem, RB and Alashhab, M and Alatise, OI and Alatresh, A and Alayeb Alayeb, MSI and Albakosh, BA and Albert, F and Alberts, ANJD and Aldarrat, AD and Alfari, A and Alfetore, A and Algbali, M and Algddar, A and Algedar, HA and ... and ASOS Investigators and ASOS investigators
The Lancet Global Health, ISSN 2214-109X, 04/2019, Volume 7, Issue 4, pp. e513 - e522
Maternal and neonatal mortality is high in Africa, but few large, prospective studies have been done to investigate the risk factors associated with these poor... 
MORTALITY | STATEMENT | MIDDLE-INCOME COUNTRIES | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | MISS | HEALTH | DEATHS | PATIENT OUTCOMES
Journal Article